PhosphoNET

           
Protein Info 
   
Short Name:  PABPN1
Full Name:  Polyadenylate-binding protein 2
Alias:  Nuclear poly(A)-binding protein 1; Oculopharyngeal muscular dystrophy; OPMD; PAB2; PABII; PABP2; Pol; Poly (A) binding protein, nuclear 1; Poly(A) binding protein 2; Poly(A)-binding protein II; PolyA binding protein II; Polyadenylate-binding nuclear protein 1; Polyadenylate-binding protein 2
Type:  RNA binding protein
Mass (Da):  32749
Number AA:  306
UniProt ID:  Q86U42
International Prot ID:  IPI00005792
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005654  GO:0030529   Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006936  GO:0000398  GO:0016973 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19GAAGGRGSGPGRRRH
Site 2Y46APGGAGDYGNGLESE
Site 3S52DYGNGLESEELEPEE
Site 4S90 APGPGPGSGAPGSQE
Site 5S95PGSGAPGSQEEEEEP
Site 6S150VEKQMNMSPPPGNAG
Site 7S162NAGPVIMSIEEKMEA
Site 8S173KMEADARSIYVGNVD
Site 9Y175EADARSIYVGNVDYG
Site 10S209TILCDKFSGHPKGFA
Site 11Y217GHPKGFAYIEFSDKE
Site 12S221GFAYIEFSDKESVRT
Site 13S225IEFSDKESVRTSLAL
Site 14S229DKESVRTSLALDESL
Site 15S235TSLALDESLFRGRQI
Site 16T249IKVIPKRTNRPGIST
Site 17T256TNRPGISTTDRGFPR
Site 18T257NRPGISTTDRGFPRA
Site 19Y266RGFPRARYRARTTNY
Site 20T270RARYRARTTNYNSSR
Site 21T271ARYRARTTNYNSSRS
Site 22Y273YRARTTNYNSSRSRF
Site 23S275ARTTNYNSSRSRFYS
Site 24S276RTTNYNSSRSRFYSG
Site 25Y281NSSRSRFYSGFNSRP
Site 26S282SSRSRFYSGFNSRPR
Site 27S286RFYSGFNSRPRGRVY
Site 28Y293SRPRGRVYRGRARAT
Site 29S301RGRARATSWYSPY__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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