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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC7B
Full Name:
Tetratricopeptide repeat protein 7B
Alias:
Tetratricopeptide repeat 7B; Tetratricopeptide repeat 7-like-1; Tetratricopeptide repeat domain 7B; Tetratricopeptide repeat protein 7-like-1; TPR repeat protein 7B; TTC7L1
Type:
Mass (Da):
94179
Number AA:
843
UniProt ID:
Q86TV6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
K
A
G
S
R
L
E
T
E
I
E
R
C
R
S
Site 2
S34
P
E
L
V
K
Q
L
S
A
K
L
I
A
N
D
Site 3
S51
A
E
L
L
L
G
E
S
K
L
E
Q
Y
L
K
Site 4
Y56
G
E
S
K
L
E
Q
Y
L
K
E
H
P
L
R
Site 5
S67
H
P
L
R
Q
G
A
S
P
R
G
P
K
P
Q
Site 6
T76
R
G
P
K
P
Q
L
T
E
V
R
K
H
L
T
Site 7
S93
L
D
R
G
N
L
K
S
E
F
L
Q
E
S
N
Site 8
Y108
L
I
M
A
K
L
N
Y
V
E
G
D
Y
K
E
Site 9
Y113
L
N
Y
V
E
G
D
Y
K
E
A
L
N
I
Y
Site 10
Y120
Y
K
E
A
L
N
I
Y
A
R
V
G
L
D
D
Site 11
S158
C
L
E
K
L
P
I
S
S
S
T
S
N
L
H
Site 12
S159
L
E
K
L
P
I
S
S
S
T
S
N
L
H
V
Site 13
S160
E
K
L
P
I
S
S
S
T
S
N
L
H
V
D
Site 14
T161
K
L
P
I
S
S
S
T
S
N
L
H
V
D
R
Site 15
S162
L
P
I
S
S
S
T
S
N
L
H
V
D
R
E
Site 16
T174
D
R
E
Q
D
V
I
T
C
Y
E
K
A
G
D
Site 17
Y176
E
Q
D
V
I
T
C
Y
E
K
A
G
D
I
A
Site 18
S196
E
I
E
R
V
I
L
S
N
I
Q
N
R
S
P
Site 19
S202
L
S
N
I
Q
N
R
S
P
K
P
G
P
A
P
Site 20
Y229
L
Q
R
A
H
V
L
Y
F
K
N
G
N
L
T
Site 21
T254
R
A
V
E
T
R
T
T
Q
N
L
R
M
T
I
Site 22
T260
T
T
Q
N
L
R
M
T
I
A
R
Q
L
A
E
Site 23
Y278
R
G
M
C
E
Q
S
Y
W
N
P
L
E
D
P
Site 24
S289
L
E
D
P
P
C
Q
S
P
L
D
D
P
L
R
Site 25
T301
P
L
R
K
G
A
N
T
K
T
Y
T
L
T
R
Site 26
T303
R
K
G
A
N
T
K
T
Y
T
L
T
R
R
A
Site 27
Y304
K
G
A
N
T
K
T
Y
T
L
T
R
R
A
R
Site 28
T305
G
A
N
T
K
T
Y
T
L
T
R
R
A
R
V
Site 29
T307
N
T
K
T
Y
T
L
T
R
R
A
R
V
Y
S
Site 30
Y313
L
T
R
R
A
R
V
Y
S
G
E
N
I
F
C
Site 31
S314
T
R
R
A
R
V
Y
S
G
E
N
I
F
C
P
Site 32
S346
A
N
R
D
A
V
L
S
R
I
P
E
H
K
S
Site 33
S353
S
R
I
P
E
H
K
S
D
R
L
I
S
L
Q
Site 34
S358
H
K
S
D
R
L
I
S
L
Q
S
A
S
V
V
Site 35
Y379
A
L
G
R
R
G
Q
Y
E
M
L
S
E
C
L
Site 36
S383
R
G
Q
Y
E
M
L
S
E
C
L
E
R
A
M
Site 37
T432
R
L
K
P
D
D
A
T
I
P
L
L
A
A
K
Site 38
T457
E
A
E
K
F
A
K
T
V
V
D
V
G
E
K
Site 39
T485
L
T
Y
S
L
Q
A
T
D
A
S
L
R
G
M
Site 40
S488
S
L
Q
A
T
D
A
S
L
R
G
M
Q
E
V
Site 41
S509
L
A
F
Q
R
A
H
S
L
S
P
T
D
H
Q
Site 42
S511
F
Q
R
A
H
S
L
S
P
T
D
H
Q
A
A
Site 43
T513
R
A
H
S
L
S
P
T
D
H
Q
A
A
F
Y
Site 44
S560
H
L
L
A
L
L
L
S
A
Q
K
H
Y
H
D
Site 45
S594
F
S
K
V
K
L
Q
S
L
C
R
G
P
D
E
Site 46
Y617
L
Q
I
W
K
S
C
Y
N
L
T
N
P
S
D
Site 47
T620
W
K
S
C
Y
N
L
T
N
P
S
D
S
G
R
Site 48
S623
C
Y
N
L
T
N
P
S
D
S
G
R
G
S
S
Site 49
S625
N
L
T
N
P
S
D
S
G
R
G
S
S
L
L
Site 50
S629
P
S
D
S
G
R
G
S
S
L
L
D
R
T
I
Site 51
S630
S
D
S
G
R
G
S
S
L
L
D
R
T
I
A
Site 52
T635
G
S
S
L
L
D
R
T
I
A
D
R
R
Q
L
Site 53
T644
A
D
R
R
Q
L
N
T
I
T
L
P
D
F
S
Site 54
T646
R
R
Q
L
N
T
I
T
L
P
D
F
S
D
P
Site 55
S651
T
I
T
L
P
D
F
S
D
P
E
T
G
S
V
Site 56
T655
P
D
F
S
D
P
E
T
G
S
V
H
A
T
S
Site 57
S657
F
S
D
P
E
T
G
S
V
H
A
T
S
V
A
Site 58
T661
E
T
G
S
V
H
A
T
S
V
A
A
S
R
V
Site 59
S662
T
G
S
V
H
A
T
S
V
A
A
S
R
V
E
Site 60
S666
H
A
T
S
V
A
A
S
R
V
E
Q
A
L
S
Site 61
S673
S
R
V
E
Q
A
L
S
E
V
A
S
S
L
Q
Site 62
S677
Q
A
L
S
E
V
A
S
S
L
Q
S
S
A
P
Site 63
S678
A
L
S
E
V
A
S
S
L
Q
S
S
A
P
K
Site 64
S681
E
V
A
S
S
L
Q
S
S
A
P
K
Q
G
P
Site 65
S682
V
A
S
S
L
Q
S
S
A
P
K
Q
G
P
L
Site 66
Y734
P
M
S
H
N
V
L
Y
M
R
G
Q
I
A
E
Site 67
S745
Q
I
A
E
L
R
G
S
M
D
E
A
R
R
W
Site 68
Y753
M
D
E
A
R
R
W
Y
E
E
A
L
A
I
S
Site 69
S760
Y
E
E
A
L
A
I
S
P
T
H
V
K
S
M
Site 70
T762
E
A
L
A
I
S
P
T
H
V
K
S
M
Q
R
Site 71
S781
L
H
Q
L
G
R
Y
S
L
A
E
K
I
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation