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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DKFZP451C023
Full Name:
Sarcalumenin
Alias:
Hypothetical protein DKFZp451C023; sarcalumenin; SRCA
Type:
Endoplasmic reticulum; Calcium-binding protein
Mass (Da):
100788
Number AA:
932
UniProt ID:
Q86TD4
International Prot ID:
IPI00328534
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0033018
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
G
Q
A
E
L
Q
V
S
A
S
G
G
T
E
D
Site 2
S42
N
L
L
E
N
H
F
S
A
G
D
A
S
L
E
Site 3
S47
H
F
S
A
G
D
A
S
L
E
E
K
E
R
A
Site 4
Y56
E
E
K
E
R
A
L
Y
A
D
T
A
P
Q
D
Site 5
Y70
D
K
K
L
L
L
H
Y
P
D
G
R
E
A
E
Site 6
S78
P
D
G
R
E
A
E
S
P
K
K
T
P
A
S
Site 7
T82
E
A
E
S
P
K
K
T
P
A
S
A
A
S
A
Site 8
S85
S
P
K
K
T
P
A
S
A
A
S
A
G
P
D
Site 9
S88
K
T
P
A
S
A
A
S
A
G
P
D
P
E
A
Site 10
S96
A
G
P
D
P
E
A
S
L
S
N
A
S
A
T
Site 11
S98
P
D
P
E
A
S
L
S
N
A
S
A
T
E
S
Site 12
S101
E
A
S
L
S
N
A
S
A
T
E
S
P
P
P
Site 13
T103
S
L
S
N
A
S
A
T
E
S
P
P
P
G
E
Site 14
S105
S
N
A
S
A
T
E
S
P
P
P
G
E
R
D
Site 15
S130
K
N
G
P
P
V
A
S
A
L
P
P
G
G
A
Site 16
S150
E
E
W
P
E
P
S
S
G
E
G
Q
G
E
E
Site 17
T168
F
G
L
P
T
E
G
T
A
S
G
E
A
G
G
Site 18
S170
L
P
T
E
G
T
A
S
G
E
A
G
G
Q
A
Site 19
S211
E
P
K
A
E
G
A
S
P
H
S
E
G
D
G
Site 20
S214
A
E
G
A
S
P
H
S
E
G
D
G
V
G
P
Site 21
S229
L
N
A
E
A
E
G
S
P
G
P
G
E
E
P
Site 22
T258
E
S
E
P
D
I
D
T
Q
A
S
E
G
T
E
Site 23
S277
P
G
P
A
A
E
A
S
A
E
P
G
G
A
Q
Site 24
S285
A
E
P
G
G
A
Q
S
V
K
A
G
D
T
E
Site 25
S294
K
A
G
D
T
E
E
S
Q
A
P
E
M
T
E
Site 26
S308
E
E
D
A
D
E
A
S
S
E
E
E
S
G
D
Site 27
S309
E
D
A
D
E
A
S
S
E
E
E
S
G
D
G
Site 28
S313
E
A
S
S
E
E
E
S
G
D
G
S
G
S
E
Site 29
S317
E
E
E
S
G
D
G
S
G
S
E
E
E
G
G
Site 30
S319
E
S
G
D
G
S
G
S
E
E
E
G
G
V
P
Site 31
S327
E
E
E
G
G
V
P
S
E
E
E
S
E
E
D
Site 32
S331
G
V
P
S
E
E
E
S
E
E
D
S
G
D
G
Site 33
S335
E
E
E
S
E
E
D
S
G
D
G
A
S
S
E
Site 34
T352
E
G
A
S
E
E
A
T
E
P
Q
E
A
G
E
Site 35
S378
D
L
Q
E
A
E
E
S
Q
E
G
G
D
P
Q
Site 36
T432
E
L
P
E
A
T
G
T
T
S
H
R
D
R
G
Site 37
S434
P
E
A
T
G
T
T
S
H
R
D
R
G
A
Q
Site 38
T449
P
G
P
E
E
L
N
T
E
S
M
G
S
E
T
Site 39
S473
E
G
H
Q
G
R
E
S
P
I
I
V
A
Q
E
Site 40
S495
E
A
P
L
R
D
R
S
H
I
E
K
T
L
M
Site 41
S509
M
L
N
E
D
K
P
S
D
D
Y
S
A
V
L
Site 42
Y512
E
D
K
P
S
D
D
Y
S
A
V
L
Q
R
L
Site 43
S513
D
K
P
S
D
D
Y
S
A
V
L
Q
R
L
R
Site 44
Y523
L
Q
R
L
R
K
I
Y
H
S
S
I
K
P
L
Site 45
S525
R
L
R
K
I
Y
H
S
S
I
K
P
L
E
Q
Site 46
Y534
I
K
P
L
E
Q
S
Y
K
Y
N
E
L
R
Q
Site 47
Y536
P
L
E
Q
S
Y
K
Y
N
E
L
R
Q
H
E
Site 48
T545
E
L
R
Q
H
E
I
T
D
G
E
I
T
S
K
Site 49
Y571
G
K
S
T
M
I
N
Y
L
L
G
L
E
N
T
Site 50
Y580
L
G
L
E
N
T
R
Y
Q
L
Y
T
G
A
E
Site 51
Y583
E
N
T
R
Y
Q
L
Y
T
G
A
E
P
T
T
Site 52
T584
N
T
R
Y
Q
L
Y
T
G
A
E
P
T
T
S
Site 53
S591
T
G
A
E
P
T
T
S
E
F
T
V
L
M
H
Site 54
T594
E
P
T
T
S
E
F
T
V
L
M
H
G
P
K
Site 55
S617
M
A
A
D
S
A
R
S
F
S
P
L
E
K
F
Site 56
S619
A
D
S
A
R
S
F
S
P
L
E
K
F
G
Q
Site 57
T650
E
R
V
T
F
V
D
T
P
G
I
I
E
N
R
Site 58
Y664
R
K
Q
Q
E
R
G
Y
P
F
N
D
V
C
Q
Site 59
S707
R
Q
L
K
G
R
E
S
Q
I
R
I
I
L
N
Site 60
Y748
V
T
E
P
P
R
V
Y
V
S
S
F
W
P
Q
Site 61
S751
P
P
R
V
Y
V
S
S
F
W
P
Q
E
Y
K
Site 62
T761
P
Q
E
Y
K
P
D
T
H
Q
E
L
F
L
Q
Site 63
S772
L
F
L
Q
E
E
I
S
L
L
E
D
L
N
Q
Site 64
Y809
H
A
L
L
V
D
R
Y
L
Q
T
Y
K
D
K
Site 65
Y813
V
D
R
Y
L
Q
T
Y
K
D
K
M
T
F
F
Site 66
T818
Q
T
Y
K
D
K
M
T
F
F
S
D
G
E
L
Site 67
S821
K
D
K
M
T
F
F
S
D
G
E
L
V
F
K
Site 68
Y838
V
E
D
P
D
K
F
Y
I
F
K
T
I
L
A
Site 69
Y860
D
L
P
N
R
E
A
Y
K
D
F
F
G
I
N
Site 70
S876
I
S
S
F
K
L
L
S
Q
Q
C
S
Y
M
G
Site 71
T895
E
K
I
E
R
A
I
T
Q
E
L
P
G
L
L
Site 72
T919
G
A
L
N
C
D
K
T
G
C
S
E
T
P
K
Site 73
T924
D
K
T
G
C
S
E
T
P
K
N
R
Y
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation