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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AlphaK2
Full Name:
Alpha-protein kinase 2
Alias:
Alpha-kinase 2; ALPK2; EC 2.7.11.-; HAK; Heart alpha-kinase
Type:
Protein kinase, atypical; EC 2.7.11.-;
ATYPICAL
group; Alpha family
Mass (Da):
237013
Number AA:
2170
UniProt ID:
Q86TB3
International Prot ID:
IPI00792557
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
C
F
L
S
T
L
L
S
Q
K
V
P
E
K
S
Site 2
S27
S
Q
K
V
P
E
K
S
D
A
V
L
R
C
I
Site 3
Y46
P
K
P
E
V
T
W
Y
K
N
G
Q
A
I
D
Site 4
S55
N
G
Q
A
I
D
G
S
G
I
I
S
N
Y
E
Site 5
Y61
G
S
G
I
I
S
N
Y
E
F
F
E
N
Q
Y
Site 6
S107
A
S
V
E
V
E
C
S
S
E
N
P
Q
L
S
Site 7
S108
S
V
E
V
E
C
S
S
E
N
P
Q
L
S
P
Site 8
S114
S
S
E
N
P
Q
L
S
P
N
L
E
D
D
R
Site 9
S154
Y
K
E
E
E
S
I
S
P
G
T
P
R
S
A
Site 10
T157
E
E
S
I
S
P
G
T
P
R
S
A
D
S
S
Site 11
S160
I
S
P
G
T
P
R
S
A
D
S
S
P
S
K
Site 12
S163
G
T
P
R
S
A
D
S
S
P
S
K
S
N
H
Site 13
S164
T
P
R
S
A
D
S
S
P
S
K
S
N
H
S
Site 14
S166
R
S
A
D
S
S
P
S
K
S
N
H
S
L
S
Site 15
S168
A
D
S
S
P
S
K
S
N
H
S
L
S
L
Q
Site 16
S171
S
P
S
K
S
N
H
S
L
S
L
Q
S
L
G
Site 17
S173
S
K
S
N
H
S
L
S
L
Q
S
L
G
N
L
Site 18
S176
N
H
S
L
S
L
Q
S
L
G
N
L
D
I
S
Site 19
S183
S
L
G
N
L
D
I
S
V
S
S
S
E
N
P
Site 20
S185
G
N
L
D
I
S
V
S
S
S
E
N
P
L
G
Site 21
S187
L
D
I
S
V
S
S
S
E
N
P
L
G
V
K
Site 22
T199
G
V
K
G
T
R
H
T
G
E
A
Y
D
P
S
Site 23
S206
T
G
E
A
Y
D
P
S
N
T
E
E
I
A
N
Site 24
S220
N
G
L
L
F
L
N
S
S
H
I
Y
E
K
Q
Site 25
S221
G
L
L
F
L
N
S
S
H
I
Y
E
K
Q
D
Site 26
Y224
F
L
N
S
S
H
I
Y
E
K
Q
D
R
C
C
Site 27
S259
P
H
D
E
G
L
R
S
S
Q
Q
N
P
K
V
Site 28
S260
H
D
E
G
L
R
S
S
Q
Q
N
P
K
V
Q
Site 29
Y269
Q
N
P
K
V
Q
K
Y
I
S
F
S
L
P
L
Site 30
S271
P
K
V
Q
K
Y
I
S
F
S
L
P
L
S
E
Site 31
Y284
S
E
A
T
A
H
I
Y
P
G
D
S
A
V
A
Site 32
S296
A
V
A
N
K
Q
P
S
P
Q
L
S
S
E
D
Site 33
S300
K
Q
P
S
P
Q
L
S
S
E
D
S
D
S
D
Site 34
S301
Q
P
S
P
Q
L
S
S
E
D
S
D
S
D
Y
Site 35
S304
P
Q
L
S
S
E
D
S
D
S
D
Y
E
L
C
Site 36
S306
L
S
S
E
D
S
D
S
D
Y
E
L
C
P
E
Site 37
Y308
S
E
D
S
D
S
D
Y
E
L
C
P
E
I
T
Site 38
T317
L
C
P
E
I
T
L
T
Y
T
E
E
F
S
D
Site 39
T319
P
E
I
T
L
T
Y
T
E
E
F
S
D
D
D
Site 40
S323
L
T
Y
T
E
E
F
S
D
D
D
L
E
Y
L
Site 41
Y329
F
S
D
D
D
L
E
Y
L
E
C
S
D
V
M
Site 42
S333
D
L
E
Y
L
E
C
S
D
V
M
T
D
Y
S
Site 43
Y339
C
S
D
V
M
T
D
Y
S
N
A
V
W
Q
R
Site 44
T351
W
Q
R
N
L
L
G
T
E
H
V
F
L
L
E
Site 45
S359
E
H
V
F
L
L
E
S
D
D
E
E
M
E
F
Site 46
S379
G
G
C
E
H
F
L
S
G
M
G
C
G
S
R
Site 47
S385
L
S
G
M
G
C
G
S
R
V
S
G
D
A
G
Site 48
S405
A
G
F
C
G
H
H
S
Q
P
Q
E
V
G
V
Site 49
S414
P
Q
E
V
G
V
R
S
S
R
V
S
K
H
G
Site 50
S415
Q
E
V
G
V
R
S
S
R
V
S
K
H
G
P
Site 51
S418
G
V
R
S
S
R
V
S
K
H
G
P
S
S
P
Site 52
S424
V
S
K
H
G
P
S
S
P
Q
T
G
M
T
L
Site 53
T427
H
G
P
S
S
P
Q
T
G
M
T
L
I
L
G
Site 54
T430
S
S
P
Q
T
G
M
T
L
I
L
G
P
H
Q
Site 55
T440
L
G
P
H
Q
D
G
T
S
S
V
T
E
Q
G
Site 56
S441
G
P
H
Q
D
G
T
S
S
V
T
E
Q
G
R
Site 57
S442
P
H
Q
D
G
T
S
S
V
T
E
Q
G
R
Y
Site 58
Y449
S
V
T
E
Q
G
R
Y
K
L
P
T
A
P
E
Site 59
T453
Q
G
R
Y
K
L
P
T
A
P
E
A
A
E
N
Site 60
Y462
P
E
A
A
E
N
D
Y
P
G
I
Q
G
E
T
Site 61
S472
I
Q
G
E
T
R
D
S
H
Q
A
R
E
E
F
Site 62
S481
Q
A
R
E
E
F
A
S
D
N
L
L
N
M
D
Site 63
S490
N
L
L
N
M
D
E
S
V
R
E
T
E
M
K
Site 64
T494
M
D
E
S
V
R
E
T
E
M
K
L
L
S
G
Site 65
S500
E
T
E
M
K
L
L
S
G
E
S
E
N
S
G
Site 66
S503
M
K
L
L
S
G
E
S
E
N
S
G
M
S
Q
Site 67
S506
L
S
G
E
S
E
N
S
G
M
S
Q
C
W
E
Site 68
S509
E
S
E
N
S
G
M
S
Q
C
W
E
T
A
A
Site 69
S527
V
G
G
K
D
L
W
S
K
R
G
S
R
K
S
Site 70
S531
D
L
W
S
K
R
G
S
R
K
S
A
R
V
R
Site 71
S534
S
K
R
G
S
R
K
S
A
R
V
R
Q
P
G
Site 72
S556
P
N
A
N
L
R
E
S
T
T
E
G
T
L
H
Site 73
T557
N
A
N
L
R
E
S
T
T
E
G
T
L
H
L
Site 74
S566
E
G
T
L
H
L
C
S
A
K
E
S
A
E
P
Site 75
S570
H
L
C
S
A
K
E
S
A
E
P
P
L
T
Q
Site 76
T576
E
S
A
E
P
P
L
T
Q
S
D
K
R
E
T
Site 77
S578
A
E
P
P
L
T
Q
S
D
K
R
E
T
S
H
Site 78
T583
T
Q
S
D
K
R
E
T
S
H
T
T
A
A
A
Site 79
S584
Q
S
D
K
R
E
T
S
H
T
T
A
A
A
T
Site 80
T586
D
K
R
E
T
S
H
T
T
A
A
A
T
G
R
Site 81
T591
S
H
T
T
A
A
A
T
G
R
S
S
H
A
D
Site 82
S595
A
A
A
T
G
R
S
S
H
A
D
A
R
E
C
Site 83
S605
D
A
R
E
C
A
I
S
T
Q
A
E
Q
E
A
Site 84
T614
Q
A
E
Q
E
A
K
T
L
Q
T
S
T
D
S
Site 85
T617
Q
E
A
K
T
L
Q
T
S
T
D
S
V
S
K
Site 86
T619
A
K
T
L
Q
T
S
T
D
S
V
S
K
E
G
Site 87
S621
T
L
Q
T
S
T
D
S
V
S
K
E
G
N
T
Site 88
S623
Q
T
S
T
D
S
V
S
K
E
G
N
T
N
C
Site 89
T639
G
E
G
M
Q
V
N
T
L
F
E
T
S
Q
V
Site 90
S644
V
N
T
L
F
E
T
S
Q
V
P
D
W
S
D
Site 91
S650
T
S
Q
V
P
D
W
S
D
P
P
Q
V
Q
V
Site 92
T660
P
Q
V
Q
V
Q
E
T
V
R
E
T
I
S
C
Site 93
T664
V
Q
E
T
V
R
E
T
I
S
C
S
Q
M
P
Site 94
S666
E
T
V
R
E
T
I
S
C
S
Q
M
P
A
F
Site 95
S668
V
R
E
T
I
S
C
S
Q
M
P
A
F
S
E
Site 96
S674
C
S
Q
M
P
A
F
S
E
P
A
G
E
E
S
Site 97
S681
S
E
P
A
G
E
E
S
P
F
T
G
T
T
T
Site 98
T684
A
G
E
E
S
P
F
T
G
T
T
T
I
S
F
Site 99
T686
E
E
S
P
F
T
G
T
T
T
I
S
F
S
N
Site 100
T687
E
S
P
F
T
G
T
T
T
I
S
F
S
N
L
Site 101
T688
S
P
F
T
G
T
T
T
I
S
F
S
N
L
G
Site 102
S692
G
T
T
T
I
S
F
S
N
L
G
G
V
H
K
Site 103
S703
G
V
H
K
E
N
A
S
L
A
Q
H
S
E
V
Site 104
T714
H
S
E
V
K
P
C
T
C
G
P
Q
H
E
E
Site 105
Y739
N
F
R
E
D
L
K
Y
E
Q
S
I
S
E
A
Site 106
S742
E
D
L
K
Y
E
Q
S
I
S
E
A
N
D
E
Site 107
S744
L
K
Y
E
Q
S
I
S
E
A
N
D
E
T
M
Site 108
T750
I
S
E
A
N
D
E
T
M
S
P
G
V
F
S
Site 109
S752
E
A
N
D
E
T
M
S
P
G
V
F
S
R
H
Site 110
S775
F
R
E
P
V
A
V
S
V
A
S
P
E
P
T
Site 111
T782
S
V
A
S
P
E
P
T
D
T
A
L
T
L
E
Site 112
T784
A
S
P
E
P
T
D
T
A
L
T
L
E
N
V
Site 113
T818
D
Q
G
T
C
F
D
T
I
D
S
L
V
G
R
Site 114
Y830
V
G
R
P
V
D
K
Y
S
P
Q
E
I
C
S
Site 115
S831
G
R
P
V
D
K
Y
S
P
Q
E
I
C
S
V
Site 116
S837
Y
S
P
Q
E
I
C
S
V
D
T
E
L
A
E
Site 117
S850
A
E
G
Q
N
K
V
S
D
L
C
S
S
N
D
Site 118
S854
N
K
V
S
D
L
C
S
S
N
D
K
T
L
E
Site 119
S855
K
V
S
D
L
C
S
S
N
D
K
T
L
E
V
Site 120
T859
L
C
S
S
N
D
K
T
L
E
V
F
F
Q
T
Site 121
S872
Q
T
Q
V
S
E
T
S
V
S
T
C
K
S
S
Site 122
S874
Q
V
S
E
T
S
V
S
T
C
K
S
S
K
D
Site 123
S878
T
S
V
S
T
C
K
S
S
K
D
G
N
S
V
Site 124
S879
S
V
S
T
C
K
S
S
K
D
G
N
S
V
M
Site 125
S884
K
S
S
K
D
G
N
S
V
M
S
P
L
F
T
Site 126
S887
K
D
G
N
S
V
M
S
P
L
F
T
S
T
F
Site 127
S899
S
T
F
T
L
N
I
S
H
T
A
S
E
G
A
Site 128
S903
L
N
I
S
H
T
A
S
E
G
A
T
G
E
N
Site 129
Y919
A
K
V
E
N
S
T
Y
P
L
A
S
T
V
H
Site 130
T924
S
T
Y
P
L
A
S
T
V
H
A
G
Q
E
Q
Site 131
S933
H
A
G
Q
E
Q
P
S
P
S
N
S
G
G
L
Site 132
S935
G
Q
E
Q
P
S
P
S
N
S
G
G
L
D
E
Site 133
S937
E
Q
P
S
P
S
N
S
G
G
L
D
E
T
Q
Site 134
T943
N
S
G
G
L
D
E
T
Q
L
L
S
S
E
N
Site 135
S947
L
D
E
T
Q
L
L
S
S
E
N
N
P
L
V
Site 136
S963
F
K
E
G
G
D
K
S
P
S
P
S
A
A
D
Site 137
S965
E
G
G
D
K
S
P
S
P
S
A
A
D
T
T
Site 138
S967
G
D
K
S
P
S
P
S
A
A
D
T
T
A
T
Site 139
T971
P
S
P
S
A
A
D
T
T
A
T
P
A
S
Y
Site 140
T972
S
P
S
A
A
D
T
T
A
T
P
A
S
Y
S
Site 141
T974
S
A
A
D
T
T
A
T
P
A
S
Y
S
S
I
Site 142
S977
D
T
T
A
T
P
A
S
Y
S
S
I
V
S
F
Site 143
S980
A
T
P
A
S
Y
S
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W
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Site 144
S983
A
S
Y
S
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P
W
E
K
P
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Site 145
T991
F
P
W
E
K
P
T
T
L
T
A
N
N
E
C
Site 146
T1005
C
F
Q
A
T
R
E
T
E
D
T
S
T
V
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Site 147
T1008
A
T
R
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E
D
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A
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Site 148
T1010
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A
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Y1022
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Site 150
S1026
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Site 151
S1044
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S1049
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S1053
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Site 154
S1068
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S1078
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Site 156
S1097
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S1099
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Site 158
S1107
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Site 159
S1111
D
N
L
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D
Site 160
T1113
L
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A
D
F
R
Site 161
S1121
V
D
R
A
D
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R
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Y
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E
N
F
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E
Site 162
Y1122
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R
A
D
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Site 163
S1131
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Site 164
S1141
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Q
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Site 165
S1143
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V
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Q
Q
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Site 166
S1147
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Site 167
S1149
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Q
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F
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Site 168
S1156
S
A
P
D
F
Q
Q
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L
P
T
T
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A
A
Site 169
T1160
F
Q
Q
S
L
P
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A
A
Q
E
E
R
Site 170
T1172
E
E
R
N
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H
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P
A
S
S
Site 171
S1175
N
L
V
P
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A
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S
R
E
G
Site 172
S1178
P
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A
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G
Q
Site 173
S1179
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Site 174
S1187
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Site 175
T1191
G
Q
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W
G
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Site 176
S1205
E
T
A
G
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Site 177
S1209
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E
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Site 178
S1222
S
D
I
L
L
E
E
S
K
E
Y
R
P
G
N
Site 179
Y1225
L
L
E
E
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K
E
Y
R
P
G
N
W
E
A
Site 180
T1240
G
N
K
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K
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A
S
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S
E
Site 181
S1246
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T
L
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A
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A
S
E
I
W
P
P
R
Q
Site 182
T1255
I
W
P
P
R
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T
N
S
E
S
K
A
S
Site 183
S1257
P
P
R
Q
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T
N
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E
S
K
A
S
D
G
Site 184
S1259
R
Q
L
T
N
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E
S
K
A
S
D
G
G
L
Site 185
S1262
T
N
S
E
S
K
A
S
D
G
G
L
I
I
P
Site 186
S1299
E
I
A
A
L
A
H
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P
E
D
A
E
S
A
Site 187
S1305
H
S
P
E
D
A
E
S
A
L
A
D
S
R
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Site 188
S1313
A
L
A
D
S
R
E
S
H
K
G
E
E
P
T
Site 189
S1322
K
G
E
E
P
T
I
S
V
H
W
R
S
L
S
Site 190
S1327
T
I
S
V
H
W
R
S
L
S
S
R
G
F
S
Site 191
S1329
S
V
H
W
R
S
L
S
S
R
G
F
S
Q
P
Site 192
S1330
V
H
W
R
S
L
S
S
R
G
F
S
Q
P
R
Site 193
S1334
S
L
S
S
R
G
F
S
Q
P
R
L
L
E
S
Site 194
S1342
Q
P
R
L
L
E
S
S
V
D
P
V
D
E
K
Site 195
S1352
P
V
D
E
K
E
L
S
V
T
D
S
L
S
A
Site 196
T1354
D
E
K
E
L
S
V
T
D
S
L
S
A
A
S
Site 197
S1356
K
E
L
S
V
T
D
S
L
S
A
A
S
E
T
Site 198
S1358
L
S
V
T
D
S
L
S
A
A
S
E
T
G
G
Site 199
S1361
T
D
S
L
S
A
A
S
E
T
G
G
K
E
N
Site 200
T1386
K
Q
L
K
M
D
H
T
A
F
F
K
K
F
L
Site 201
S1402
C
P
K
I
L
E
S
S
V
D
P
I
D
E
I
Site 202
S1410
V
D
P
I
D
E
I
S
V
I
E
Y
T
R
A
Site 203
Y1414
D
E
I
S
V
I
E
Y
T
R
A
G
K
P
E
Site 204
T1425
G
K
P
E
P
S
E
T
T
P
Q
G
A
R
E
Site 205
T1426
K
P
E
P
S
E
T
T
P
Q
G
A
R
E
G
Site 206
S1436
G
A
R
E
G
G
Q
S
N
D
G
N
M
G
H
Site 207
S1463
C
L
Q
G
T
I
L
S
E
N
R
I
S
R
S
Site 208
S1468
I
L
S
E
N
R
I
S
R
S
Q
E
G
S
M
Site 209
S1470
S
E
N
R
I
S
R
S
Q
E
G
S
M
K
Q
Site 210
S1474
I
S
R
S
Q
E
G
S
M
K
Q
E
A
E
Q
Site 211
T1489
I
Q
P
E
E
A
K
T
A
I
W
Q
V
L
Q
Site 212
S1506
E
G
G
E
R
I
P
S
G
C
S
I
G
Q
I
Site 213
S1516
S
I
G
Q
I
Q
E
S
S
D
G
S
L
G
E
Site 214
S1517
I
G
Q
I
Q
E
S
S
D
G
S
L
G
E
A
Site 215
S1520
I
Q
E
S
S
D
G
S
L
G
E
A
E
Q
S
Site 216
S1527
S
L
G
E
A
E
Q
S
K
K
D
K
A
E
L
Site 217
S1536
K
D
K
A
E
L
I
S
P
T
S
P
L
S
S
Site 218
S1560
L
G
V
D
T
H
N
S
T
G
Q
I
H
D
V
Site 219
Y1580
V
E
P
R
K
R
Q
Y
V
F
P
V
S
Q
K
Site 220
S1585
R
Q
Y
V
F
P
V
S
Q
K
R
G
T
I
E
Site 221
T1590
P
V
S
Q
K
R
G
T
I
E
N
E
R
G
K
Site 222
S1601
E
R
G
K
P
L
P
S
S
P
D
L
T
R
F
Site 223
S1602
R
G
K
P
L
P
S
S
P
D
L
T
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F
P
Site 224
T1606
L
P
S
S
P
D
L
T
R
F
P
C
T
S
S
Site 225
T1611
D
L
T
R
F
P
C
T
S
S
P
E
G
N
V
Site 226
S1612
L
T
R
F
P
C
T
S
S
P
E
G
N
V
T
Site 227
S1613
T
R
F
P
C
T
S
S
P
E
G
N
V
T
D
Site 228
T1619
S
S
P
E
G
N
V
T
D
F
L
I
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H
K
Site 229
T1640
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V
L
Q
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G
E
T
K
P
P
S
S
S
S
Site 230
S1644
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G
E
T
K
P
P
S
S
S
S
S
S
A
K
Site 231
S1645
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E
T
K
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P
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S
S
S
S
S
A
K
T
Site 232
S1646
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T
K
P
P
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S
S
S
S
S
A
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T
L
Site 233
S1647
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K
P
P
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S
S
S
S
A
K
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A
Site 234
S1648
K
P
P
S
S
S
S
S
S
A
K
T
L
A
F
Site 235
S1649
P
P
S
S
S
S
S
S
A
K
T
L
A
F
I
Site 236
T1652
S
S
S
S
S
A
K
T
L
A
F
I
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G
E
Site 237
S1657
A
K
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F
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G
E
R
E
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E
K
Site 238
S1684
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L
G
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A
K
K
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R
E
K
S
L
Site 239
S1690
K
S
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E
R
E
K
S
L
E
A
R
A
G
K
Site 240
S1698
L
E
A
R
A
G
K
S
P
G
T
L
T
A
V
Site 241
T1701
R
A
G
K
S
P
G
T
L
T
A
V
T
G
S
Site 242
T1703
G
K
S
P
G
T
L
T
A
V
T
G
S
E
E
Site 243
S1720
R
K
P
E
A
P
G
S
G
H
L
A
E
G
V
Site 244
S1752
K
E
N
I
R
K
N
S
A
F
L
K
K
M
P
Site 245
S1764
K
M
P
K
L
E
T
S
L
S
H
T
E
E
K
Site 246
S1766
P
K
L
E
T
S
L
S
H
T
E
E
K
Q
D
Site 247
T1768
L
E
T
S
L
S
H
T
E
E
K
Q
D
P
K
Site 248
S1778
K
Q
D
P
K
K
P
S
C
K
R
E
G
R
A
Site 249
S1801
A
E
M
F
P
E
H
S
G
N
V
K
L
S
C
Site 250
T1818
A
E
I
H
E
D
S
T
I
C
W
T
K
D
S
Site 251
S1827
C
W
T
K
D
S
K
S
I
A
Q
V
Q
R
S
Site 252
S1834
S
I
A
Q
V
Q
R
S
A
G
D
N
S
T
V
Site 253
S1839
Q
R
S
A
G
D
N
S
T
V
S
F
A
I
V
Site 254
T1840
R
S
A
G
D
N
S
T
V
S
F
A
I
V
Q
Site 255
S1849
S
F
A
I
V
Q
A
S
P
K
D
Q
G
L
Y
Site 256
Y1856
S
P
K
D
Q
G
L
Y
Y
C
C
I
K
N
S
Site 257
Y1857
P
K
D
Q
G
L
Y
Y
C
C
I
K
N
S
Y
Site 258
S1882
A
E
V
L
K
Q
L
S
S
R
Q
D
T
K
G
Site 259
S1883
E
V
L
K
Q
L
S
S
R
Q
D
T
K
G
C
Site 260
T1887
Q
L
S
S
R
Q
D
T
K
G
C
E
E
I
E
Site 261
S1896
G
C
E
E
I
E
F
S
Q
L
I
F
K
E
D
Site 262
S1908
K
E
D
F
L
H
D
S
Y
F
G
G
R
L
R
Site 263
Y1909
E
D
F
L
H
D
S
Y
F
G
G
R
L
R
G
Site 264
T1920
R
L
R
G
Q
I
A
T
E
E
L
H
F
G
E
Site 265
T1937
H
R
K
A
F
R
S
T
V
M
H
G
L
M
P
Site 266
Y1975
D
E
L
I
Q
R
N
Y
K
L
A
A
Q
E
C
Site 267
Y1983
K
L
A
A
Q
E
C
Y
V
Q
N
T
A
R
Y
Site 268
T1987
Q
E
C
Y
V
Q
N
T
A
R
Y
Y
A
K
I
Site 269
Y1991
V
Q
N
T
A
R
Y
Y
A
K
I
Y
A
A
E
Site 270
Y2026
R
P
E
N
N
I
P
Y
A
T
V
E
E
E
L
Site 271
T2028
E
N
N
I
P
Y
A
T
V
E
E
E
L
I
G
Site 272
Y2040
L
I
G
E
F
V
K
Y
S
I
R
D
G
K
E
Site 273
S2041
I
G
E
F
V
K
Y
S
I
R
D
G
K
E
I
Site 274
S2055
I
N
F
L
R
R
E
S
E
A
G
Q
K
C
C
Site 275
T2095
L
T
D
V
G
I
A
T
L
A
K
G
Y
K
G
Site 276
Y2124
A
L
H
Q
C
N
K
Y
C
K
M
L
G
L
K
Site 277
S2132
C
K
M
L
G
L
K
S
L
Q
N
N
N
Q
K
Site 278
S2148
K
Q
P
S
I
G
K
S
K
V
Q
T
N
S
M
Site 279
T2152
I
G
K
S
K
V
Q
T
N
S
M
T
I
K
K
Site 280
S2154
K
S
K
V
Q
T
N
S
M
T
I
K
K
A
G
Site 281
T2164
I
K
K
A
G
P
E
T
P
G
E
K
K
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation