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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VIGR
Full Name:
G-protein coupled receptor 126
Alias:
FLJ14937; G protein-coupled receptor 126; GP126; GPR126
Type:
Receptor, GPCR
Mass (Da):
136695
Number AA:
1221
UniProt ID:
Q86SQ4
International Prot ID:
IPI00423340
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007218
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S49
R
V
V
L
S
N
P
S
G
T
F
T
S
P
C
Site 2
T51
V
L
S
N
P
S
G
T
F
T
S
P
C
Y
P
Site 3
T53
S
N
P
S
G
T
F
T
S
P
C
Y
P
N
D
Site 4
S54
N
P
S
G
T
F
T
S
P
C
Y
P
N
D
Y
Site 5
Y57
G
T
F
T
S
P
C
Y
P
N
D
Y
P
N
S
Site 6
Y61
S
P
C
Y
P
N
D
Y
P
N
S
Q
A
C
M
Site 7
Y96
E
E
A
P
N
C
I
Y
D
S
L
S
L
D
N
Site 8
S98
A
P
N
C
I
Y
D
S
L
S
L
D
N
G
E
Site 9
S100
N
C
I
Y
D
S
L
S
L
D
N
G
E
S
Q
Site 10
S106
L
S
L
D
N
G
E
S
Q
T
K
F
C
G
A
Site 11
S119
G
A
T
A
K
G
L
S
F
N
S
S
A
N
E
Site 12
S122
A
K
G
L
S
F
N
S
S
A
N
E
M
H
V
Site 13
S123
K
G
L
S
F
N
S
S
A
N
E
M
H
V
S
Site 14
S130
S
A
N
E
M
H
V
S
F
S
S
D
F
S
I
Site 15
S132
N
E
M
H
V
S
F
S
S
D
F
S
I
Q
K
Site 16
S136
V
S
F
S
S
D
F
S
I
Q
K
K
G
F
N
Site 17
S145
Q
K
K
G
F
N
A
S
Y
I
R
V
A
V
S
Site 18
Y167
L
P
Q
T
S
D
A
Y
Q
V
S
V
A
K
S
Site 19
S197
T
K
V
G
H
E
D
S
D
W
T
A
F
S
Y
Site 20
S203
D
S
D
W
T
A
F
S
Y
S
N
A
S
F
T
Site 21
Y204
S
D
W
T
A
F
S
Y
S
N
A
S
F
T
Q
Site 22
T210
S
Y
S
N
A
S
F
T
Q
L
L
S
F
G
K
Site 23
S214
A
S
F
T
Q
L
L
S
F
G
K
A
K
S
G
Site 24
Y222
F
G
K
A
K
S
G
Y
F
L
S
I
S
D
S
Site 25
S225
A
K
S
G
Y
F
L
S
I
S
D
S
K
C
L
Site 26
Y272
G
V
N
F
K
R
N
Y
E
T
V
P
C
D
S
Site 27
S295
N
G
K
L
L
L
G
S
N
Q
N
E
I
V
S
Site 28
Y308
V
S
L
K
G
D
I
Y
N
F
R
L
W
N
F
Site 29
S323
T
M
N
A
K
I
L
S
N
L
S
C
N
V
K
Site 30
S384
L
C
Q
A
T
V
N
S
P
S
T
T
P
P
T
Site 31
S386
Q
A
T
V
N
S
P
S
T
T
P
P
T
V
T
Site 32
T387
A
T
V
N
S
P
S
T
T
P
P
T
V
T
T
Site 33
T388
T
V
N
S
P
S
T
T
P
P
T
V
T
T
N
Site 34
T391
S
P
S
T
T
P
P
T
V
T
T
N
M
P
V
Site 35
T399
V
T
T
N
M
P
V
T
N
R
I
D
K
Q
R
Site 36
S458
V
N
I
S
F
H
L
S
A
G
E
D
K
I
K
Site 37
S469
D
K
I
K
V
K
R
S
L
E
D
E
P
R
L
Site 38
S507
K
L
L
K
N
N
E
S
L
D
E
G
L
R
L
Site 39
T516
D
E
G
L
R
L
H
T
V
N
V
R
Q
L
G
Site 40
Y534
A
M
E
E
P
K
G
Y
Y
W
P
S
I
Q
P
Site 41
Y544
P
S
I
Q
P
S
E
Y
V
L
P
C
P
D
K
Site 42
S557
D
K
P
G
F
S
A
S
R
I
C
F
Y
N
A
Site 43
S603
A
D
G
Q
N
L
T
S
A
N
I
T
N
I
V
Site 44
T607
N
L
T
S
A
N
I
T
N
I
V
E
Q
V
K
Site 45
T626
K
E
E
N
I
D
I
T
L
G
S
T
L
M
N
Site 46
S642
F
S
N
I
L
S
S
S
D
S
D
L
L
E
S
Site 47
S644
N
I
L
S
S
S
D
S
D
L
L
E
S
S
S
Site 48
S649
S
D
S
D
L
L
E
S
S
S
E
A
L
K
T
Site 49
S651
S
D
L
L
E
S
S
S
E
A
L
K
T
I
D
Site 50
T656
S
S
S
E
A
L
K
T
I
D
E
L
A
F
K
Site 51
S668
A
F
K
I
D
L
N
S
T
S
H
V
N
I
T
Site 52
S670
K
I
D
L
N
S
T
S
H
V
N
I
T
T
R
Site 53
S702
N
F
S
I
G
L
P
S
N
N
E
S
Y
F
Q
Site 54
S706
G
L
P
S
N
N
E
S
Y
F
Q
M
D
F
E
Site 55
Y707
L
P
S
N
N
E
S
Y
F
Q
M
D
F
E
S
Site 56
S734
P
N
L
L
E
N
L
S
P
E
D
S
V
L
V
Site 57
S738
E
N
L
S
P
E
D
S
V
L
V
R
R
A
Q
Site 58
T747
L
V
R
R
A
Q
F
T
F
F
N
K
T
G
L
Site 59
T764
D
V
G
P
Q
R
K
T
L
V
S
Y
V
M
A
Site 60
S828
G
C
V
A
H
R
D
S
D
A
S
E
T
V
C
Site 61
S831
A
H
R
D
S
D
A
S
E
T
V
C
L
C
N
Site 62
S852
V
L
M
D
L
P
R
S
A
S
Q
L
D
A
R
Site 63
S854
M
D
L
P
R
S
A
S
Q
L
D
A
R
N
T
Site 64
T861
S
Q
L
D
A
R
N
T
K
V
L
T
F
I
S
Site 65
Y896
F
E
K
L
R
R
D
Y
P
S
K
I
L
M
N
Site 66
S898
K
L
R
R
D
Y
P
S
K
I
L
M
N
L
S
Site 67
T965
A
L
V
K
V
F
N
T
Y
I
R
R
Y
I
L
Site 68
Y999
S
R
N
N
N
E
V
Y
G
K
E
S
Y
G
K
Site 69
S1055
C
G
R
N
G
K
R
S
N
R
T
L
R
E
E
Site 70
T1058
N
G
K
R
S
N
R
T
L
R
E
E
V
L
R
Site 71
S1140
R
F
R
L
A
D
N
S
D
W
S
K
T
A
T
Site 72
T1147
S
D
W
S
K
T
A
T
N
I
I
K
K
S
S
Site 73
S1153
A
T
N
I
I
K
K
S
S
D
N
L
G
K
S
Site 74
S1160
S
S
D
N
L
G
K
S
L
S
S
S
S
I
G
Site 75
S1162
D
N
L
G
K
S
L
S
S
S
S
I
G
S
N
Site 76
S1164
L
G
K
S
L
S
S
S
S
I
G
S
N
S
T
Site 77
S1165
G
K
S
L
S
S
S
S
I
G
S
N
S
T
Y
Site 78
S1168
L
S
S
S
S
I
G
S
N
S
T
Y
L
T
S
Site 79
S1170
S
S
S
I
G
S
N
S
T
Y
L
T
S
K
S
Site 80
T1171
S
S
I
G
S
N
S
T
Y
L
T
S
K
S
K
Site 81
Y1172
S
I
G
S
N
S
T
Y
L
T
S
K
S
K
S
Site 82
T1174
G
S
N
S
T
Y
L
T
S
K
S
K
S
S
S
Site 83
S1175
S
N
S
T
Y
L
T
S
K
S
K
S
S
S
T
Site 84
S1177
S
T
Y
L
T
S
K
S
K
S
S
S
T
T
Y
Site 85
S1179
Y
L
T
S
K
S
K
S
S
S
T
T
Y
F
K
Site 86
S1181
T
S
K
S
K
S
S
S
T
T
Y
F
K
R
N
Site 87
T1183
K
S
K
S
S
S
T
T
Y
F
K
R
N
S
H
Site 88
Y1184
S
K
S
S
S
T
T
Y
F
K
R
N
S
H
T
Site 89
S1189
T
T
Y
F
K
R
N
S
H
T
D
N
V
S
Y
Site 90
T1191
Y
F
K
R
N
S
H
T
D
N
V
S
Y
E
H
Site 91
S1195
N
S
H
T
D
N
V
S
Y
E
H
S
F
N
K
Site 92
Y1196
S
H
T
D
N
V
S
Y
E
H
S
F
N
K
S
Site 93
S1199
D
N
V
S
Y
E
H
S
F
N
K
S
G
S
L
Site 94
S1203
Y
E
H
S
F
N
K
S
G
S
L
R
Q
C
F
Site 95
S1205
H
S
F
N
K
S
G
S
L
R
Q
C
F
H
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation