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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPCR149
Full Name:
Probable G-protein coupled receptor 149
Alias:
G protein-coupled receptor 149; GP149; GPR149; G-protein coupled receptor PGR10; IEDA; PGR10
Type:
Unknown function
Mass (Da):
80965
Number AA:
731
UniProt ID:
Q86SP6
International Prot ID:
IPI00328434
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
L
F
L
S
N
L
S
T
N
D
S
Site 2
S9
S
L
F
L
S
N
L
S
T
N
D
S
S
L
W
Site 3
T10
L
F
L
S
N
L
S
T
N
D
S
S
L
W
K
Site 4
S13
S
N
L
S
T
N
D
S
S
L
W
K
E
N
H
Site 5
S14
N
L
S
T
N
D
S
S
L
W
K
E
N
H
N
Site 6
S57
G
S
I
Y
S
L
I
S
L
L
K
M
Q
N
R
Site 7
Y100
W
P
N
E
V
P
G
Y
F
Q
F
L
C
T
T
Site 8
Y129
K
A
T
L
L
V
S
Y
N
F
Y
T
M
H
R
Site 9
S140
T
M
H
R
G
V
G
S
Q
T
A
S
R
R
S
Site 10
T142
H
R
G
V
G
S
Q
T
A
S
R
R
S
G
Q
Site 11
S144
G
V
G
S
Q
T
A
S
R
R
S
G
Q
V
L
Site 12
S147
S
Q
T
A
S
R
R
S
G
Q
V
L
G
V
V
Site 13
S227
E
E
P
P
R
L
H
S
N
Y
Q
E
I
S
R
Site 14
Y229
P
P
R
L
H
S
N
Y
Q
E
I
S
R
G
A
Site 15
S233
H
S
N
Y
Q
E
I
S
R
G
A
S
I
P
G
Site 16
S237
Q
E
I
S
R
G
A
S
I
P
G
T
P
P
T
Site 17
T241
R
G
A
S
I
P
G
T
P
P
T
A
G
R
V
Site 18
S250
P
T
A
G
R
V
V
S
L
S
P
E
D
A
P
Site 19
S252
A
G
R
V
V
S
L
S
P
E
D
A
P
G
P
Site 20
S260
P
E
D
A
P
G
P
S
L
R
R
S
G
G
C
Site 21
S264
P
G
P
S
L
R
R
S
G
G
C
S
P
S
S
Site 22
S268
L
R
R
S
G
G
C
S
P
S
S
D
T
V
F
Site 23
S270
R
S
G
G
C
S
P
S
S
D
T
V
F
G
P
Site 24
S271
S
G
G
C
S
P
S
S
D
T
V
F
G
P
G
Site 25
T273
G
C
S
P
S
S
D
T
V
F
G
P
G
A
P
Site 26
T295
C
R
R
E
N
R
G
T
L
Y
G
T
R
S
F
Site 27
Y297
R
E
N
R
G
T
L
Y
G
T
R
S
F
T
V
Site 28
T303
L
Y
G
T
R
S
F
T
V
S
V
A
Q
K
R
Site 29
S305
G
T
R
S
F
T
V
S
V
A
Q
K
R
F
A
Site 30
Y383
I
N
C
R
Q
N
A
Y
A
V
A
S
D
G
K
Site 31
S402
K
G
F
E
F
N
L
S
F
Q
K
S
Y
G
I
Site 32
Y410
F
Q
K
S
Y
G
I
Y
K
I
A
H
E
D
Y
Site 33
Y417
Y
K
I
A
H
E
D
Y
Y
D
D
D
E
N
S
Site 34
Y418
K
I
A
H
E
D
Y
Y
D
D
D
E
N
S
I
Site 35
T438
M
N
S
E
C
E
T
T
K
D
P
Q
R
D
N
Site 36
S457
N
A
I
K
V
E
I
S
T
T
P
S
L
D
S
Site 37
T459
I
K
V
E
I
S
T
T
P
S
L
D
S
S
T
Site 38
S461
V
E
I
S
T
T
P
S
L
D
S
S
T
Q
R
Site 39
S465
T
T
P
S
L
D
S
S
T
Q
R
G
I
N
K
Site 40
T466
T
P
S
L
D
S
S
T
Q
R
G
I
N
K
C
Site 41
T479
K
C
T
N
T
D
I
T
E
A
K
Q
D
S
N
Site 42
S493
N
N
K
K
D
A
F
S
D
K
T
G
G
D
I
Site 43
T496
K
D
A
F
S
D
K
T
G
G
D
I
N
Y
E
Site 44
Y502
K
T
G
G
D
I
N
Y
E
E
T
T
F
S
E
Site 45
T506
D
I
N
Y
E
E
T
T
F
S
E
G
P
E
R
Site 46
S508
N
Y
E
E
T
T
F
S
E
G
P
E
R
R
L
Site 47
S516
E
G
P
E
R
R
L
S
H
E
E
S
Q
K
P
Site 48
S520
R
R
L
S
H
E
E
S
Q
K
P
D
L
S
D
Site 49
S526
E
S
Q
K
P
D
L
S
D
W
E
W
C
R
S
Site 50
S533
S
D
W
E
W
C
R
S
K
S
E
R
T
P
R
Site 51
S535
W
E
W
C
R
S
K
S
E
R
T
P
R
Q
R
Site 52
T538
C
R
S
K
S
E
R
T
P
R
Q
R
S
G
Y
Site 53
S543
E
R
T
P
R
Q
R
S
G
Y
A
L
A
I
P
Site 54
Y545
T
P
R
Q
R
S
G
Y
A
L
A
I
P
L
C
Site 55
S559
C
A
F
Q
G
T
V
S
L
H
A
P
T
G
K
Site 56
T567
L
H
A
P
T
G
K
T
L
S
L
S
T
Y
E
Site 57
S569
A
P
T
G
K
T
L
S
L
S
T
Y
E
V
S
Site 58
S571
T
G
K
T
L
S
L
S
T
Y
E
V
S
A
E
Site 59
Y573
K
T
L
S
L
S
T
Y
E
V
S
A
E
G
Q
Site 60
T583
S
A
E
G
Q
K
I
T
P
A
S
K
K
I
E
Site 61
S586
G
Q
K
I
T
P
A
S
K
K
I
E
V
Y
R
Site 62
Y592
A
S
K
K
I
E
V
Y
R
S
K
S
V
G
H
Site 63
S594
K
K
I
E
V
Y
R
S
K
S
V
G
H
E
P
Site 64
S596
I
E
V
Y
R
S
K
S
V
G
H
E
P
N
S
Site 65
S603
S
V
G
H
E
P
N
S
E
D
S
S
S
T
F
Site 66
S606
H
E
P
N
S
E
D
S
S
S
T
F
V
D
T
Site 67
S607
E
P
N
S
E
D
S
S
S
T
F
V
D
T
S
Site 68
S608
P
N
S
E
D
S
S
S
T
F
V
D
T
S
V
Site 69
T609
N
S
E
D
S
S
S
T
F
V
D
T
S
V
K
Site 70
T613
S
S
S
T
F
V
D
T
S
V
K
I
H
L
E
Site 71
T633
D
N
E
E
A
L
D
T
V
S
I
I
S
N
I
Site 72
S635
E
E
A
L
D
T
V
S
I
I
S
N
I
S
Q
Site 73
S641
V
S
I
I
S
N
I
S
Q
S
S
T
Q
V
R
Site 74
S644
I
S
N
I
S
Q
S
S
T
Q
V
R
S
P
S
Site 75
T645
S
N
I
S
Q
S
S
T
Q
V
R
S
P
S
L
Site 76
S649
Q
S
S
T
Q
V
R
S
P
S
L
R
Y
S
R
Site 77
S651
S
T
Q
V
R
S
P
S
L
R
Y
S
R
K
E
Site 78
S655
R
S
P
S
L
R
Y
S
R
K
E
N
R
F
V
Site 79
S663
R
K
E
N
R
F
V
S
C
D
L
G
E
T
A
Site 80
Y672
D
L
G
E
T
A
S
Y
S
L
F
L
P
T
S
Site 81
S673
L
G
E
T
A
S
Y
S
L
F
L
P
T
S
N
Site 82
T678
S
Y
S
L
F
L
P
T
S
N
P
D
G
D
I
Site 83
S679
Y
S
L
F
L
P
T
S
N
P
D
G
D
I
N
Site 84
S688
P
D
G
D
I
N
I
S
I
P
D
T
V
E
A
Site 85
T692
I
N
I
S
I
P
D
T
V
E
A
H
R
Q
N
Site 86
S700
V
E
A
H
R
Q
N
S
K
R
Q
H
Q
E
R
Site 87
Y710
Q
H
Q
E
R
D
G
Y
Q
E
E
I
Q
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation