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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DSG4
Full Name:
Desmoglein-4
Alias:
Cadherin family member 13
Type:
Mass (Da):
113824
Number AA:
1040
UniProt ID:
Q86SJ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T43
N
G
T
T
K
W
Q
T
V
R
R
Q
K
R
E
Site 2
S65
C
R
E
G
E
D
N
S
K
R
N
P
I
A
K
Site 3
T120
S
V
V
D
R
E
I
T
P
L
F
L
I
Y
C
Site 4
S204
K
I
V
S
Q
E
P
S
G
A
P
M
F
I
L
Site 5
T544
D
M
W
D
V
R
S
T
N
A
T
S
A
I
L
Site 6
T665
R
Q
P
E
G
L
G
T
R
F
A
P
V
P
E
Site 7
S694
H
P
E
D
R
D
V
S
N
I
C
A
P
M
T
Site 8
T701
S
N
I
C
A
P
M
T
A
S
N
T
Q
D
R
Site 9
T705
A
P
M
T
A
S
N
T
Q
D
R
M
D
S
S
Site 10
S711
N
T
Q
D
R
M
D
S
S
E
I
Y
T
N
T
Site 11
S712
T
Q
D
R
M
D
S
S
E
I
Y
T
N
T
Y
Site 12
Y715
R
M
D
S
S
E
I
Y
T
N
T
Y
A
A
G
Site 13
T716
M
D
S
S
E
I
Y
T
N
T
Y
A
A
G
G
Site 14
T718
S
S
E
I
Y
T
N
T
Y
A
A
G
G
T
V
Site 15
Y719
S
E
I
Y
T
N
T
Y
A
A
G
G
T
V
E
Site 16
T724
N
T
Y
A
A
G
G
T
V
E
G
G
V
S
G
Site 17
S760
S
G
A
A
R
K
R
S
S
T
M
G
T
L
R
Site 18
S761
G
A
A
R
K
R
S
S
T
M
G
T
L
R
D
Site 19
T762
A
A
R
K
R
S
S
T
M
G
T
L
R
D
Y
Site 20
T765
K
R
S
S
T
M
G
T
L
R
D
Y
A
D
A
Site 21
Y769
T
M
G
T
L
R
D
Y
A
D
A
D
I
N
M
Site 22
Y782
N
M
A
F
L
D
S
Y
F
S
E
K
A
Y
A
Site 23
S784
A
F
L
D
S
Y
F
S
E
K
A
Y
A
Y
A
Site 24
Y788
S
Y
F
S
E
K
A
Y
A
Y
A
D
E
D
E
Site 25
Y806
A
N
D
C
L
L
I
Y
D
H
E
G
V
G
S
Site 26
S813
Y
D
H
E
G
V
G
S
P
V
G
S
I
G
C
Site 27
S831
I
V
D
D
L
D
E
S
C
M
E
T
L
D
P
Site 28
T835
L
D
E
S
C
M
E
T
L
D
P
K
F
R
T
Site 29
Y875
L
P
L
L
G
P
N
Y
F
V
N
E
S
S
G
Site 30
T884
V
N
E
S
S
G
L
T
P
S
E
V
E
F
Q
Site 31
S886
E
S
S
G
L
T
P
S
E
V
E
F
Q
E
E
Site 32
S897
F
Q
E
E
M
A
A
S
E
P
V
V
H
G
D
Site 33
Y959
V
P
A
E
L
A
D
Y
N
N
V
I
Y
A
E
Site 34
Y964
A
D
Y
N
N
V
I
Y
A
E
R
V
L
A
S
Site 35
S971
Y
A
E
R
V
L
A
S
P
G
V
P
D
M
S
Site 36
S978
S
P
G
V
P
D
M
S
N
S
S
T
T
E
G
Site 37
S980
G
V
P
D
M
S
N
S
S
T
T
E
G
C
M
Site 38
S981
V
P
D
M
S
N
S
S
T
T
E
G
C
M
G
Site 39
T982
P
D
M
S
N
S
S
T
T
E
G
C
M
G
P
Site 40
T1016
P
D
L
P
I
G
Q
T
V
G
S
T
S
P
M
Site 41
S1019
P
I
G
Q
T
V
G
S
T
S
P
M
T
S
R
Site 42
S1021
G
Q
T
V
G
S
T
S
P
M
T
S
R
H
R
Site 43
T1024
V
G
S
T
S
P
M
T
S
R
H
R
V
T
R
Site 44
S1025
G
S
T
S
P
M
T
S
R
H
R
V
T
R
Y
Site 45
Y1032
S
R
H
R
V
T
R
Y
S
N
I
H
Y
T
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation