PhosphoNET

           
Protein Info 
   
Short Name:  NPM2
Full Name:  Nucleoplasmin-2
Alias: 
Type: 
Mass (Da):  24152
Number AA:  214
UniProt ID:  Q86SE8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S5___MNLSSASSTEEK
Site 2S8MNLSSASSTEEKAVT
Site 3T9NLSSASSTEEKAVTT
Site 4T15STEEKAVTTVLWGCE
Site 5T29ELSQERRTWTFRPQL
Site 6T31SQERRTWTFRPQLEG
Site 7S41PQLEGKQSCRLLLHT
Site 8T79DKKMQPVTIASLQAS
Site 9S86TIASLQASVLPMVSM
Site 10S116GSGPVFLSGQERYEA
Site 11T127RYEASDLTWEEEEEE
Site 12S154EDEDADISLEEQSPV
Site 13S159DISLEEQSPVKQVKR
Site 14S191EEEEIRASVRDKSPV
Site 15S196RASVRDKSPVKKAKA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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