PhosphoNET

           
Protein Info 
   
Short Name:  MEGF8
Full Name:  Multiple epidermal growth factor-like domains protein 8
Alias:  Epidermal growth factor-like protein 4
Type: 
Mass (Da):  303100
Number AA:  2845
UniProt ID:  Q7Z7M0
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S20LALAVLGSLSPGARA
Site 2S1169DCGCSFHSHCRKRGP
Site 3S1198CERCRPGSFGNATGS
Site 4Y1250QLCSPGYYGDPRAGG
Site 5S1258GDPRAGGSCFRECGG
Site 6S1790RPRLFHASALLGDTM
Site 7T1796ASALLGDTMVVLGGR
Site 8T2690RRHLQEMTKMASRPF
Site 9T2701SRPFAKVTVCFPPDP
Site 10T2709VCFPPDPTAPASAWK
Site 11S2713PDPTAPASAWKPAGL
Site 12S2728PPPAFRRSEPFLAPL
Site 13T2769GLRAGPITLEPTEDG
Site 14Y2813LRHRLHEYCGGGGGA
Site 15S2823GGGGAGGSGHGTGAG
Site 16T2827AGGSGHGTGAGRKGL
Site 17S2836AGRKGLLSQDNLTSM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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