PhosphoNET

           
Protein Info 
   
Short Name:  Slob
Full Name:  PX domain-containing protein kinase-like protein
Alias:  Modulator of Na,K-ATPase; MONaKA; PXK
Type:  Protein-serine kinase, Other group, Slob family
Mass (Da):  64950
Number AA:  578
UniProt ID:  Q7Z7A4
International Prot ID:  IPI00479912
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0019898  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0003779  GO:0035091 PhosphoSite+ KinaseNET
Biological Process:  GO:0007154  GO:0006954  GO:0032780 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S27LTAAIEASQSLQSHT
Site 2S29AAIEASQSLQSHTEY
Site 3Y36SLQSHTEYIIRVQRG
Site 4S45IRVQRGISVENSWQI
Site 5S49RGISVENSWQIVRRY
Site 6Y56SWQIVRRYSDFDLLN
Site 7S57WQIVRRYSDFDLLNN
Site 8Y99RQKGLQNYLNVITTN
Site 9Y124KFLDPNNYSANYTEI
Site 10T129NNYSANYTEIALQQV
Site 11Y163GWRIRKKYFLMKIKN
Site 12S179PKERLVLSWADLGPD
Site 13Y188ADLGPDKYLSDKDFQ
Site 14S190LGPDKYLSDKDFQCL
Site 15T213HPYIYRVTFATANES
Site 16Y239GTLKDLIYKAKPKDP
Site 17Y251KDPFLKKYCNPKKIQ
Site 18T267LELQQIKTYGRQILE
Site 19Y268ELQQIKTYGRQILEV
Site 20Y286LHDKGFPYGHLHASN
Site 21S292PYGHLHASNVMLDGD
Site 22S315NSLLGLPSFYRSYFS
Site 23S319GLPSFYRSYFSQFRK
Site 24Y320LPSFYRSYFSQFRKI
Site 25S322SFYRSYFSQFRKINT
Site 26Y343HCFGHLLYEMTYGRP
Site 27T346GHLLYEMTYGRPPDS
Site 28Y347HLLYEMTYGRPPDSV
Site 29S353TYGRPPDSVPVDSFP
Site 30S358PDSVPVDSFPPAPSM
Site 31T386ACKNGMPTISRLLQM
Site 32S404SDVLLTTSEKPQFKI
Site 33T444IHQHRRLTRAQSHHG
Site 34S448RRLTRAQSHHGSEEE
Site 35S452RAQSHHGSEEERKKR
Site 36S467KILARKKSKRSALEN
Site 37S470ARKKSKRSALENSEE
Site 38S475KRSALENSEEHSAKY
Site 39S479LENSEEHSAKYSNSN
Site 40Y482SEEHSAKYSNSNNSA
Site 41S483EEHSAKYSNSNNSAG
Site 42S485HSAKYSNSNNSAGSG
Site 43S488KYSNSNNSAGSGASS
Site 44S491NSNNSAGSGASSPLT
Site 45S495SAGSGASSPLTSPSS
Site 46T498SGASSPLTSPSSPTP
Site 47S499GASSPLTSPSSPTPP
Site 48S501SSPLTSPSSPTPPST
Site 49S502SPLTSPSSPTPPSTS
Site 50T504LTSPSSPTPPSTSGI
Site 51S507PSSPTPPSTSGISAL
Site 52T508SSPTPPSTSGISALP
Site 53S509SPTPPSTSGISALPP
Site 54S512PPSTSGISALPPPPP
Site 55S541EAPAQLSSQAVNGMS
Site 56S554MSRGALLSSIQNFQK
Site 57S555SRGALLSSIQNFQKG
Site 58T569GTLRKAKTCDHSAPK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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