PhosphoNET

           
Protein Info 
   
Short Name:  YTHDF3
Full Name:  YTH domain family protein 3
Alias:  YTH domain 3; YTH domain, 3; YTHD3
Type:  Uncharacterized cytoplasm protein
Mass (Da):  63861
Number AA:  585
UniProt ID:  Q7Z739
International Prot ID:  IPI00396131
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0044424  GO:0044464 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSATSVDQR
Site 2S18KGQGNKVSVQNGSIH
Site 3S23KVSVQNGSIHQKDAV
Site 4Y38NDDDFEPYLSSQTNQ
Site 5S40DDFEPYLSSQTNQSN
Site 6S41DFEPYLSSQTNQSNS
Site 7S46LSSQTNQSNSYPPMS
Site 8S48SQTNQSNSYPPMSDP
Site 9Y49QTNQSNSYPPMSDPY
Site 10S53SNSYPPMSDPYMPSY
Site 11Y56YPPMSDPYMPSYYAP
Site 12S59MSDPYMPSYYAPSIG
Site 13Y60SDPYMPSYYAPSIGF
Site 14Y61DPYMPSYYAPSIGFP
Site 15S70PSIGFPYSLGEAAWS
Site 16S77SLGEAAWSTAGDQPM
Site 17Y86AGDQPMPYLTTYGQM
Site 18Y90PMPYLTTYGQMSNGE
Site 19Y100MSNGEHHYIPDGVFS
Site 20S107YIPDGVFSQPGALGN
Site 21T115QPGALGNTPPFLGQH
Site 22S134FPGNADFSTWGTSGS
Site 23T135PGNADFSTWGTSGSQ
Site 24T138ADFSTWGTSGSQGQS
Site 25S139DFSTWGTSGSQGQST
Site 26S141STWGTSGSQGQSTQS
Site 27S145TSGSQGQSTQSSAYS
Site 28T146SGSQGQSTQSSAYSS
Site 29S148SQGQSTQSSAYSSSY
Site 30S149QGQSTQSSAYSSSYG
Site 31Y151QSTQSSAYSSSYGYP
Site 32S152STQSSAYSSSYGYPP
Site 33S153TQSSAYSSSYGYPPS
Site 34S154QSSAYSSSYGYPPSS
Site 35Y155SSAYSSSYGYPPSSL
Site 36Y157AYSSSYGYPPSSLGR
Site 37S160SSYGYPPSSLGRAIT
Site 38S161SYGYPPSSLGRAITD
Site 39T167SSLGRAITDGQAGFG
Site 40T177QAGFGNDTLSKVPGI
Site 41S179GFGNDTLSKVPGISS
Site 42S186SKVPGISSIEQGMTG
Site 43T192SSIEQGMTGLKIGGD
Site 44T201LKIGGDLTAAVTKTV
Site 45S230NSVPPVSSAAPKPTS
Site 46S237SAAPKPTSWAAIARK
Site 47T291SVVKAPPTQPVLPPQ
Site 48S316QPPPLVQSQLPQQQP
Site 49S372NQNNGAGSENFGLGV
Site 50S383GLGVVPVSASPSSVE
Site 51S385GVVPVSASPSSVEVH
Site 52S423GRVFIIKSYSEDDIH
Site 53S425VFIIKSYSEDDIHRS
Site 54Y435DIHRSIKYSIWCSTE
Site 55S436IHRSIKYSIWCSTEH
Site 56S440IKYSIWCSTEHGNKR
Site 57Y452NKRLDAAYRSLNGKG
Site 58S454RLDAAYRSLNGKGPL
Site 59Y485EMKSVVDYNAYAGVW
Site 60Y488SVVDYNAYAGVWSQD
Site 61T530NNDNKPVTNSRDTQE
Site 62T535PVTNSRDTQEVPLEK
Site 63Y566IFDDFAHYEKRQEEE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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