PhosphoNET

           
Protein Info 
   
Short Name:  TMCO2
Full Name:  Transmembrane and coiled-coil domain-containing protein 2
Alias: 
Type: 
Mass (Da):  20071
Number AA:  182
UniProt ID:  Q7Z6W1
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MSTSSSSSWDNLL
Site 2S8MSTSSSSSWDNLLES
Site 3S15SWDNLLESLSLSTVW
Site 4S17DNLLESLSLSTVWNW
Site 5S34ASFLGETSAPQQTSL
Site 6S40TSAPQQTSLGLLDNL
Site 7S58VQIILRISFLILLGI
Site 8Y68ILLGIGIYALWKRSI
Site 9S96YKLYKKGSHIFEALL
Site 10S122DNNNLFLSLGLQEKI
Site 11T135KILKKLKTVENKMKN
Site 12T154IVAQKPATKRDCSSE
Site 13S159PATKRDCSSEPYCSC
Site 14S160ATKRDCSSEPYCSCS
Site 15Y163RDCSSEPYCSCSDCQ
Site 16S165CSSEPYCSCSDCQSP
Site 17S167SEPYCSCSDCQSPLS
Site 18S171CSCSDCQSPLSTSGF
Site 19S174SDCQSPLSTSGFTSP
Site 20T175DCQSPLSTSGFTSPI
Site 21S176CQSPLSTSGFTSPI_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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