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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TFAP2D
Full Name:
Transcription factor AP-2-delta
Alias:
Activating enhancer-binding protein 2-delta;Transcription factor AP-2-beta-like 1
Type:
Mass (Da):
49578
Number AA:
452
UniProt ID:
Q7Z6R9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
A
E
I
R
H
D
G
S
N
S
Y
R
L
M
Q
Site 2
S21
I
R
H
D
G
S
N
S
Y
R
L
M
Q
L
G
Site 3
T37
L
E
S
V
A
N
S
T
V
A
Y
S
S
S
S
Site 4
Y40
V
A
N
S
T
V
A
Y
S
S
S
S
P
L
T
Site 5
S41
A
N
S
T
V
A
Y
S
S
S
S
P
L
T
Y
Site 6
S42
N
S
T
V
A
Y
S
S
S
S
P
L
T
Y
S
Site 7
S43
S
T
V
A
Y
S
S
S
S
P
L
T
Y
S
T
Site 8
S44
T
V
A
Y
S
S
S
S
P
L
T
Y
S
T
T
Site 9
T47
Y
S
S
S
S
P
L
T
Y
S
T
T
G
T
E
Site 10
Y48
S
S
S
S
P
L
T
Y
S
T
T
G
T
E
F
Site 11
S49
S
S
S
P
L
T
Y
S
T
T
G
T
E
F
A
Site 12
T53
L
T
Y
S
T
T
G
T
E
F
A
S
P
Y
F
Site 13
S57
T
T
G
T
E
F
A
S
P
Y
F
S
T
N
H
Site 14
Y59
G
T
E
F
A
S
P
Y
F
S
T
N
H
Q
Y
Site 15
T67
F
S
T
N
H
Q
Y
T
P
L
H
H
Q
S
F
Site 16
T86
Q
H
S
H
P
A
V
T
P
D
A
Y
S
L
N
Site 17
Y90
P
A
V
T
P
D
A
Y
S
L
N
S
L
H
H
Site 18
S91
A
V
T
P
D
A
Y
S
L
N
S
L
H
H
S
Site 19
S94
P
D
A
Y
S
L
N
S
L
H
H
S
Q
Q
Y
Site 20
Y101
S
L
H
H
S
Q
Q
Y
Y
Q
Q
I
H
H
G
Site 21
Y102
L
H
H
S
Q
Q
Y
Y
Q
Q
I
H
H
G
E
Site 22
S124
H
N
A
R
A
L
K
S
S
C
L
D
E
Q
R
Site 23
S125
N
A
R
A
L
K
S
S
C
L
D
E
Q
R
R
Site 24
Y140
E
L
G
C
L
D
A
Y
R
R
H
D
L
S
L
Site 25
S146
A
Y
R
R
H
D
L
S
L
M
S
H
G
S
Q
Site 26
S149
R
H
D
L
S
L
M
S
H
G
S
Q
Y
G
M
Site 27
S152
L
S
L
M
S
H
G
S
Q
Y
G
M
H
P
D
Site 28
S181
G
A
D
D
L
Q
G
S
V
E
A
Q
C
G
L
Site 29
T202
G
V
I
R
R
G
G
T
C
V
V
N
P
T
D
Site 30
S219
C
S
V
P
G
R
L
S
L
L
S
S
T
S
K
Site 31
S222
P
G
R
L
S
L
L
S
S
T
S
K
Y
K
V
Site 32
S223
G
R
L
S
L
L
S
S
T
S
K
Y
K
V
T
Site 33
S225
L
S
L
L
S
S
T
S
K
Y
K
V
T
I
A
Site 34
S239
A
E
V
K
R
R
L
S
P
P
E
C
L
N
A
Site 35
S258
G
I
L
R
R
A
K
S
K
N
G
G
R
C
L
Site 36
T287
R
R
K
A
A
N
V
T
L
L
T
S
L
V
E
Site 37
Y306
H
L
A
R
D
F
G
Y
T
C
E
T
E
F
P
Site 38
T307
L
A
R
D
F
G
Y
T
C
E
T
E
F
P
A
Site 39
T310
D
F
G
Y
T
C
E
T
E
F
P
A
K
A
V
Site 40
T341
R
K
K
M
I
L
A
T
K
Q
I
C
K
E
F
Site 41
S353
K
E
F
Q
D
L
L
S
Q
D
R
S
P
L
G
Site 42
S357
D
L
L
S
Q
D
R
S
P
L
G
S
S
R
P
Site 43
S361
Q
D
R
S
P
L
G
S
S
R
P
T
P
I
L
Site 44
T365
P
L
G
S
S
R
P
T
P
I
L
D
L
D
I
Site 45
T377
L
D
I
Q
R
H
L
T
H
F
S
L
I
T
H
Site 46
S403
S
T
F
Q
T
V
L
S
E
M
L
N
Y
L
E
Site 47
Y408
V
L
S
E
M
L
N
Y
L
E
K
H
T
T
H
Site 48
T414
N
Y
L
E
K
H
T
T
H
K
N
G
G
A
A
Site 49
S423
K
N
G
G
A
A
D
S
G
Q
G
H
A
N
S
Site 50
S430
S
G
Q
G
H
A
N
S
E
K
A
P
L
R
K
Site 51
T438
E
K
A
P
L
R
K
T
S
E
A
A
V
K
E
Site 52
S439
K
A
P
L
R
K
T
S
E
A
A
V
K
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation