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Updated November 2019
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Protein Info
Short Name:
RAI1
Full Name:
Retinoic acid-induced protein 1
Alias:
DKFZP434A139; KIAA1820; MGC12824; Retinoic acid induced 1; SMCR; SMS
Type:
Transcription factor
Mass (Da):
203352
Number AA:
1906
UniProt ID:
Q7Z5J4
International Prot ID:
IPI00449923
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
F
H
G
K
Q
Q
N
Y
Q
Q
T
S
Q
E
T
Site 2
S21
Q
Q
N
Y
Q
Q
T
S
Q
E
T
S
R
L
E
Site 3
S25
Q
Q
T
S
Q
E
T
S
R
L
E
N
Y
R
Q
Site 4
Y30
E
T
S
R
L
E
N
Y
R
Q
P
S
Q
A
G
Site 5
S34
L
E
N
Y
R
Q
P
S
Q
A
G
L
S
C
D
Site 6
S39
Q
P
S
Q
A
G
L
S
C
D
R
Q
R
L
L
Site 7
Y50
Q
R
L
L
A
K
D
Y
Y
N
P
Q
P
Y
P
Site 8
Y51
R
L
L
A
K
D
Y
Y
N
P
Q
P
Y
P
S
Site 9
Y56
D
Y
Y
N
P
Q
P
Y
P
S
Y
E
G
G
A
Site 10
S58
Y
N
P
Q
P
Y
P
S
Y
E
G
G
A
G
T
Site 11
Y59
N
P
Q
P
Y
P
S
Y
E
G
G
A
G
T
P
Site 12
T65
S
Y
E
G
G
A
G
T
P
S
G
T
A
A
A
Site 13
Y78
A
A
V
A
A
D
K
Y
H
R
G
S
K
A
L
Site 14
S82
A
D
K
Y
H
R
G
S
K
A
L
P
T
Q
Q
Site 15
T87
R
G
S
K
A
L
P
T
Q
Q
G
L
Q
G
R
Site 16
Y100
G
R
P
A
F
P
G
Y
G
V
Q
D
S
S
P
Site 17
S105
P
G
Y
G
V
Q
D
S
S
P
Y
P
G
R
Y
Site 18
S106
G
Y
G
V
Q
D
S
S
P
Y
P
G
R
Y
A
Site 19
Y108
G
V
Q
D
S
S
P
Y
P
G
R
Y
A
G
E
Site 20
Y112
S
S
P
Y
P
G
R
Y
A
G
E
E
S
L
Q
Site 21
S117
G
R
Y
A
G
E
E
S
L
Q
A
W
G
A
P
Site 22
Y141
L
P
A
G
V
A
K
Y
D
E
N
L
M
K
K
Site 23
T149
D
E
N
L
M
K
K
T
A
V
P
P
S
R
Q
Site 24
S154
K
K
T
A
V
P
P
S
R
Q
Y
A
E
Q
G
Site 25
Y157
A
V
P
P
S
R
Q
Y
A
E
Q
G
A
Q
V
Site 26
S170
Q
V
P
F
R
T
H
S
L
H
V
Q
Q
P
P
Site 27
Y185
P
P
Q
Q
P
L
A
Y
P
K
L
Q
R
Q
K
Site 28
S199
K
L
Q
N
D
I
A
S
P
L
P
F
P
Q
G
Site 29
T207
P
L
P
F
P
Q
G
T
H
F
P
Q
H
S
Q
Site 30
S213
G
T
H
F
P
Q
H
S
Q
S
F
P
T
S
S
Site 31
S215
H
F
P
Q
H
S
Q
S
F
P
T
S
S
T
Y
Site 32
S219
H
S
Q
S
F
P
T
S
S
T
Y
S
S
S
V
Site 33
S220
S
Q
S
F
P
T
S
S
T
Y
S
S
S
V
Q
Site 34
T221
Q
S
F
P
T
S
S
T
Y
S
S
S
V
Q
G
Site 35
Y222
S
F
P
T
S
S
T
Y
S
S
S
V
Q
G
G
Site 36
S223
F
P
T
S
S
T
Y
S
S
S
V
Q
G
G
G
Site 37
S224
P
T
S
S
T
Y
S
S
S
V
Q
G
G
G
Q
Site 38
S225
T
S
S
T
Y
S
S
S
V
Q
G
G
G
Q
G
Site 39
S235
G
G
G
Q
G
A
H
S
Y
K
S
C
T
A
P
Site 40
Y236
G
G
Q
G
A
H
S
Y
K
S
C
T
A
P
T
Site 41
S238
Q
G
A
H
S
Y
K
S
C
T
A
P
T
A
Q
Site 42
T252
Q
P
H
D
R
P
L
T
A
S
S
S
L
A
P
Site 43
S254
H
D
R
P
L
T
A
S
S
S
L
A
P
G
Q
Site 44
S256
R
P
L
T
A
S
S
S
L
A
P
G
Q
R
V
Site 45
Y269
R
V
Q
N
L
H
A
Y
Q
S
G
R
L
S
Y
Site 46
S271
Q
N
L
H
A
Y
Q
S
G
R
L
S
Y
D
Q
Site 47
S275
A
Y
Q
S
G
R
L
S
Y
D
Q
Q
Q
Q
Q
Site 48
Y276
Y
Q
S
G
R
L
S
Y
D
Q
Q
Q
Q
Q
Q
Site 49
Y305
H
A
Q
E
T
L
H
Y
Q
N
L
A
K
Y
Q
Site 50
Y311
H
Y
Q
N
L
A
K
Y
Q
H
Y
G
Q
Q
G
Site 51
Y314
N
L
A
K
Y
Q
H
Y
G
Q
Q
G
Q
G
Y
Site 52
Y321
Y
G
Q
Q
G
Q
G
Y
C
Q
P
D
A
A
V
Site 53
T330
Q
P
D
A
A
V
R
T
P
E
Q
Y
Y
Q
T
Site 54
Y334
A
V
R
T
P
E
Q
Y
Y
Q
T
F
S
P
S
Site 55
Y335
V
R
T
P
E
Q
Y
Y
Q
T
F
S
P
S
S
Site 56
T337
T
P
E
Q
Y
Y
Q
T
F
S
P
S
S
S
H
Site 57
S339
E
Q
Y
Y
Q
T
F
S
P
S
S
S
H
S
P
Site 58
S341
Y
Y
Q
T
F
S
P
S
S
S
H
S
P
A
R
Site 59
S342
Y
Q
T
F
S
P
S
S
S
H
S
P
A
R
S
Site 60
S343
Q
T
F
S
P
S
S
S
H
S
P
A
R
S
V
Site 61
S345
F
S
P
S
S
S
H
S
P
A
R
S
V
G
R
Site 62
S349
S
S
H
S
P
A
R
S
V
G
R
S
P
S
Y
Site 63
S353
P
A
R
S
V
G
R
S
P
S
Y
S
S
T
P
Site 64
S355
R
S
V
G
R
S
P
S
Y
S
S
T
P
S
P
Site 65
Y356
S
V
G
R
S
P
S
Y
S
S
T
P
S
P
L
Site 66
S357
V
G
R
S
P
S
Y
S
S
T
P
S
P
L
M
Site 67
S358
G
R
S
P
S
Y
S
S
T
P
S
P
L
M
P
Site 68
T359
R
S
P
S
Y
S
S
T
P
S
P
L
M
P
N
Site 69
S361
P
S
Y
S
S
T
P
S
P
L
M
P
N
L
E
Site 70
Y372
P
N
L
E
N
F
P
Y
S
Q
Q
P
L
S
T
Site 71
S373
N
L
E
N
F
P
Y
S
Q
Q
P
L
S
T
G
Site 72
S378
P
Y
S
Q
Q
P
L
S
T
G
A
F
P
A
G
Site 73
S399
F
M
P
L
L
N
P
S
P
T
D
A
T
S
S
Site 74
T401
P
L
L
N
P
S
P
T
D
A
T
S
S
V
D
Site 75
S405
P
S
P
T
D
A
T
S
S
V
D
T
Q
A
G
Site 76
S406
S
P
T
D
A
T
S
S
V
D
T
Q
A
G
N
Site 77
T409
D
A
T
S
S
V
D
T
Q
A
G
N
C
K
P
Site 78
S428
K
L
P
E
N
L
L
S
D
L
S
L
Q
S
L
Site 79
S440
Q
S
L
T
A
L
T
S
Q
V
E
N
I
S
N
Site 80
S470
K
G
V
K
N
L
V
S
R
T
P
E
Q
H
K
Site 81
T472
V
K
N
L
V
S
R
T
P
E
Q
H
K
S
Q
Site 82
S478
R
T
P
E
Q
H
K
S
Q
H
C
S
P
E
G
Site 83
S482
Q
H
K
S
Q
H
C
S
P
E
G
S
G
Y
S
Site 84
S486
Q
H
C
S
P
E
G
S
G
Y
S
A
E
P
A
Site 85
Y488
C
S
P
E
G
S
G
Y
S
A
E
P
A
G
T
Site 86
S489
S
P
E
G
S
G
Y
S
A
E
P
A
G
T
P
Site 87
T495
Y
S
A
E
P
A
G
T
P
L
S
E
P
P
S
Site 88
S498
E
P
A
G
T
P
L
S
E
P
P
S
S
T
P
Site 89
S502
T
P
L
S
E
P
P
S
S
T
P
Q
S
T
H
Site 90
S503
P
L
S
E
P
P
S
S
T
P
Q
S
T
H
A
Site 91
T504
L
S
E
P
P
S
S
T
P
Q
S
T
H
A
E
Site 92
S507
P
P
S
S
T
P
Q
S
T
H
A
E
P
Q
E
Site 93
Y517
A
E
P
Q
E
A
D
Y
L
S
G
S
E
D
P
Site 94
S519
P
Q
E
A
D
Y
L
S
G
S
E
D
P
L
E
Site 95
S521
E
A
D
Y
L
S
G
S
E
D
P
L
E
R
S
Site 96
S528
S
E
D
P
L
E
R
S
F
L
Y
C
N
Q
A
Site 97
Y531
P
L
E
R
S
F
L
Y
C
N
Q
A
R
G
S
Site 98
S538
Y
C
N
Q
A
R
G
S
P
A
R
V
N
S
N
Site 99
S544
G
S
P
A
R
V
N
S
N
S
K
A
K
P
E
Site 100
S546
P
A
R
V
N
S
N
S
K
A
K
P
E
S
V
Site 101
S552
N
S
K
A
K
P
E
S
V
S
T
C
S
V
T
Site 102
S554
K
A
K
P
E
S
V
S
T
C
S
V
T
S
P
Site 103
T555
A
K
P
E
S
V
S
T
C
S
V
T
S
P
D
Site 104
S557
P
E
S
V
S
T
C
S
V
T
S
P
D
D
M
Site 105
T559
S
V
S
T
C
S
V
T
S
P
D
D
M
S
T
Site 106
S560
V
S
T
C
S
V
T
S
P
D
D
M
S
T
K
Site 107
S565
V
T
S
P
D
D
M
S
T
K
S
D
D
S
F
Site 108
T566
T
S
P
D
D
M
S
T
K
S
D
D
S
F
Q
Site 109
S568
P
D
D
M
S
T
K
S
D
D
S
F
Q
S
L
Site 110
S571
M
S
T
K
S
D
D
S
F
Q
S
L
H
G
S
Site 111
S574
K
S
D
D
S
F
Q
S
L
H
G
S
L
P
L
Site 112
S578
S
F
Q
S
L
H
G
S
L
P
L
D
S
F
S
Site 113
S585
S
L
P
L
D
S
F
S
K
F
V
A
G
E
R
Site 114
S609
L
A
Q
E
D
L
A
S
E
I
L
G
L
Q
E
Site 115
S631
K
A
W
A
E
A
P
S
L
V
K
D
S
S
K
Site 116
S636
A
P
S
L
V
K
D
S
S
K
P
P
F
S
L
Site 117
S637
P
S
L
V
K
D
S
S
K
P
P
F
S
L
E
Site 118
S642
D
S
S
K
P
P
F
S
L
E
N
H
S
A
C
Site 119
S652
N
H
S
A
C
L
D
S
V
A
K
S
A
W
P
Site 120
S656
C
L
D
S
V
A
K
S
A
W
P
R
P
G
E
Site 121
S670
E
P
E
A
L
P
D
S
L
Q
L
D
K
G
G
Site 122
S683
G
G
N
A
K
D
F
S
P
G
L
F
E
D
P
Site 123
S691
P
G
L
F
E
D
P
S
V
A
F
A
T
P
D
Site 124
T696
D
P
S
V
A
F
A
T
P
D
P
K
K
T
T
Site 125
T702
A
T
P
D
P
K
K
T
T
G
P
L
S
F
G
Site 126
S707
K
K
T
T
G
P
L
S
F
G
T
K
P
T
L
Site 127
T732
A
F
D
C
F
P
D
T
T
A
A
S
S
A
D
Site 128
T733
F
D
C
F
P
D
T
T
A
A
S
S
A
D
S
Site 129
S736
F
P
D
T
T
A
A
S
S
A
D
S
A
N
P
Site 130
S740
T
A
A
S
S
A
D
S
A
N
P
F
A
W
P
Site 131
S776
L
E
Q
G
G
K
A
S
D
G
I
S
K
G
D
Site 132
S780
G
K
A
S
D
G
I
S
K
G
D
T
H
E
A
Site 133
T784
D
G
I
S
K
G
D
T
H
E
A
S
A
C
L
Site 134
S788
K
G
D
T
H
E
A
S
A
C
L
G
F
Q
E
Site 135
S805
P
P
G
E
K
V
A
S
L
P
G
D
F
K
Q
Site 136
T847
D
S
R
H
C
C
S
T
A
D
F
G
D
L
P
Site 137
T859
D
L
P
L
L
P
P
T
S
R
K
E
D
L
E
Site 138
S860
L
P
L
L
P
P
T
S
R
K
E
D
L
E
A
Site 139
S872
L
E
A
E
E
E
Y
S
S
L
C
E
L
L
G
Site 140
S873
E
A
E
E
E
Y
S
S
L
C
E
L
L
G
S
Site 141
S880
S
L
C
E
L
L
G
S
P
E
Q
R
P
G
M
Site 142
S892
P
G
M
Q
D
P
L
S
P
K
A
P
L
I
C
Site 143
S910
E
V
E
E
V
L
D
S
K
A
G
W
G
S
P
Site 144
S916
D
S
K
A
G
W
G
S
P
C
H
L
S
G
E
Site 145
S921
W
G
S
P
C
H
L
S
G
E
S
V
I
L
L
Site 146
S936
G
P
T
V
G
T
E
S
K
V
Q
S
W
F
E
Site 147
S940
G
T
E
S
K
V
Q
S
W
F
E
S
S
L
S
Site 148
S944
K
V
Q
S
W
F
E
S
S
L
S
H
M
K
P
Site 149
S945
V
Q
S
W
F
E
S
S
L
S
H
M
K
P
G
Site 150
S947
S
W
F
E
S
S
L
S
H
M
K
P
G
E
E
Site 151
S965
G
E
R
A
P
G
D
S
T
T
S
D
A
S
L
Site 152
T966
E
R
A
P
G
D
S
T
T
S
D
A
S
L
A
Site 153
T967
R
A
P
G
D
S
T
T
S
D
A
S
L
A
Q
Site 154
S968
A
P
G
D
S
T
T
S
D
A
S
L
A
Q
K
Site 155
S971
D
S
T
T
S
D
A
S
L
A
Q
K
P
N
K
Site 156
S997
E
P
V
P
R
G
K
S
L
R
S
R
R
V
H
Site 157
S1000
P
R
G
K
S
L
R
S
R
R
V
H
R
G
L
Site 158
S1013
G
L
P
E
A
E
D
S
P
C
R
A
P
V
L
Site 159
S1029
K
D
L
L
L
P
E
S
C
T
G
P
P
Q
G
Site 160
T1031
L
L
L
P
E
S
C
T
G
P
P
Q
G
Q
M
Site 161
S1049
G
A
P
G
R
G
A
S
E
G
L
P
R
M
C
Site 162
T1057
E
G
L
P
R
M
C
T
R
S
L
T
A
L
S
Site 163
S1059
L
P
R
M
C
T
R
S
L
T
A
L
S
E
P
Site 164
T1061
R
M
C
T
R
S
L
T
A
L
S
E
P
R
T
Site 165
S1064
T
R
S
L
T
A
L
S
E
P
R
T
P
G
P
Site 166
T1068
T
A
L
S
E
P
R
T
P
G
P
P
G
L
T
Site 167
T1075
T
P
G
P
P
G
L
T
T
T
P
A
P
P
D
Site 168
T1076
P
G
P
P
G
L
T
T
T
P
A
P
P
D
K
Site 169
T1077
G
P
P
G
L
T
T
T
P
A
P
P
D
K
L
Site 170
S1094
K
Q
R
A
A
F
K
S
G
K
R
V
G
K
P
Site 171
S1102
G
K
R
V
G
K
P
S
P
K
A
A
S
S
P
Site 172
S1107
K
P
S
P
K
A
A
S
S
P
S
N
P
A
A
Site 173
S1108
P
S
P
K
A
A
S
S
P
S
N
P
A
A
L
Site 174
S1110
P
K
A
A
S
S
P
S
N
P
A
A
L
P
V
Site 175
S1119
P
A
A
L
P
V
A
S
D
S
S
P
M
G
S
Site 176
S1121
A
L
P
V
A
S
D
S
S
P
M
G
S
K
T
Site 177
S1122
L
P
V
A
S
D
S
S
P
M
G
S
K
T
K
Site 178
S1126
S
D
S
S
P
M
G
S
K
T
K
E
T
D
S
Site 179
T1128
S
S
P
M
G
S
K
T
K
E
T
D
S
P
S
Site 180
T1131
M
G
S
K
T
K
E
T
D
S
P
S
T
P
G
Site 181
S1133
S
K
T
K
E
T
D
S
P
S
T
P
G
K
D
Site 182
S1135
T
K
E
T
D
S
P
S
T
P
G
K
D
Q
R
Site 183
T1136
K
E
T
D
S
P
S
T
P
G
K
D
Q
R
S
Site 184
S1143
T
P
G
K
D
Q
R
S
M
I
L
R
S
R
T
Site 185
T1150
S
M
I
L
R
S
R
T
K
T
Q
E
I
F
H
Site 186
T1152
I
L
R
S
R
T
K
T
Q
E
I
F
H
S
K
Site 187
S1158
K
T
Q
E
I
F
H
S
K
R
R
R
P
S
E
Site 188
S1164
H
S
K
R
R
R
P
S
E
G
R
L
P
N
C
Site 189
T1174
R
L
P
N
C
R
A
T
K
K
L
L
D
N
S
Site 190
S1181
T
K
K
L
L
D
N
S
H
L
P
A
T
F
K
Site 191
T1186
D
N
S
H
L
P
A
T
F
K
V
S
S
S
P
Site 192
S1192
A
T
F
K
V
S
S
S
P
Q
K
E
G
R
V
Site 193
S1200
P
Q
K
E
G
R
V
S
Q
R
A
R
V
P
K
Site 194
S1215
P
G
A
G
S
K
L
S
D
R
P
L
H
A
L
Site 195
S1226
L
H
A
L
K
R
K
S
A
F
M
A
P
V
P
Site 196
S1243
K
R
N
L
V
L
R
S
R
S
S
S
S
S
N
Site 197
S1245
N
L
V
L
R
S
R
S
S
S
S
S
N
A
S
Site 198
S1246
L
V
L
R
S
R
S
S
S
S
S
N
A
S
G
Site 199
S1247
V
L
R
S
R
S
S
S
S
S
N
A
S
G
N
Site 200
S1248
L
R
S
R
S
S
S
S
S
N
A
S
G
N
G
Site 201
S1249
R
S
R
S
S
S
S
S
N
A
S
G
N
G
G
Site 202
S1252
S
S
S
S
S
N
A
S
G
N
G
G
D
G
K
Site 203
S1266
K
E
E
R
P
E
G
S
P
T
L
F
K
R
M
Site 204
T1268
E
R
P
E
G
S
P
T
L
F
K
R
M
S
S
Site 205
S1274
P
T
L
F
K
R
M
S
S
P
K
K
A
K
P
Site 206
S1275
T
L
F
K
R
M
S
S
P
K
K
A
K
P
T
Site 207
T1290
K
G
N
G
E
P
A
T
K
L
P
P
P
E
T
Site 208
T1297
T
K
L
P
P
P
E
T
P
D
A
C
L
K
L
Site 209
T1316
A
F
Q
G
A
M
K
T
K
V
L
P
P
R
K
Site 210
S1340
V
Q
K
I
T
S
P
S
L
K
K
F
A
C
K
Site 211
S1352
A
C
K
A
P
G
A
S
P
G
N
P
L
S
P
Site 212
S1358
A
S
P
G
N
P
L
S
P
S
L
S
D
K
D
Site 213
S1360
P
G
N
P
L
S
P
S
L
S
D
K
D
R
G
Site 214
S1362
N
P
L
S
P
S
L
S
D
K
D
R
G
L
K
Site 215
S1374
G
L
K
G
A
G
G
S
P
V
G
V
E
E
G
Site 216
T1387
E
G
L
V
N
V
G
T
G
Q
K
L
P
T
S
Site 217
S1394
T
G
Q
K
L
P
T
S
G
A
D
P
L
C
R
Site 218
T1404
D
P
L
C
R
N
P
T
N
R
S
L
K
G
K
Site 219
S1407
C
R
N
P
T
N
R
S
L
K
G
K
L
M
N
Site 220
S1415
L
K
G
K
L
M
N
S
K
K
L
S
S
T
D
Site 221
S1419
L
M
N
S
K
K
L
S
S
T
D
C
F
K
T
Site 222
T1421
N
S
K
K
L
S
S
T
D
C
F
K
T
E
A
Site 223
T1426
S
S
T
D
C
F
K
T
E
A
F
T
S
P
E
Site 224
T1430
C
F
K
T
E
A
F
T
S
P
E
A
L
Q
P
Site 225
S1431
F
K
T
E
A
F
T
S
P
E
A
L
Q
P
G
Site 226
S1448
A
L
A
P
K
K
R
S
R
K
G
R
A
G
A
Site 227
T1476
L
G
P
A
L
L
L
T
P
R
D
R
A
S
G
Site 228
S1482
L
T
P
R
D
R
A
S
G
T
Q
G
A
S
E
Site 229
T1484
P
R
D
R
A
S
G
T
Q
G
A
S
E
D
N
Site 230
S1488
A
S
G
T
Q
G
A
S
E
D
N
S
G
G
G
Site 231
S1492
Q
G
A
S
E
D
N
S
G
G
G
G
K
K
P
Site 232
S1508
M
E
E
L
G
L
A
S
Q
P
P
E
G
R
P
Site 233
T1520
G
R
P
C
Q
P
Q
T
R
A
Q
K
Q
P
G
Site 234
T1529
A
Q
K
Q
P
G
H
T
N
Y
S
S
Y
S
K
Site 235
Y1531
K
Q
P
G
H
T
N
Y
S
S
Y
S
K
R
K
Site 236
S1533
P
G
H
T
N
Y
S
S
Y
S
K
R
K
R
L
Site 237
S1535
H
T
N
Y
S
S
Y
S
K
R
K
R
L
T
R
Site 238
T1541
Y
S
K
R
K
R
L
T
R
G
R
A
K
N
T
Site 239
T1549
R
G
R
A
K
N
T
T
S
S
P
C
K
G
R
Site 240
S1551
R
A
K
N
T
T
S
S
P
C
K
G
R
A
K
Site 241
Y1579
E
P
E
I
R
L
K
Y
I
S
S
C
K
R
L
Site 242
S1581
E
I
R
L
K
Y
I
S
S
C
K
R
L
R
S
Site 243
S1582
I
R
L
K
Y
I
S
S
C
K
R
L
R
S
D
Site 244
S1588
S
S
C
K
R
L
R
S
D
S
R
T
P
A
F
Site 245
S1590
C
K
R
L
R
S
D
S
R
T
P
A
F
S
P
Site 246
T1592
R
L
R
S
D
S
R
T
P
A
F
S
P
F
V
Site 247
S1596
D
S
R
T
P
A
F
S
P
F
V
R
V
E
K
Site 248
T1609
E
K
R
D
A
F
T
T
I
C
T
V
V
N
S
Site 249
S1616
T
I
C
T
V
V
N
S
P
G
D
A
P
K
P
Site 250
S1628
P
K
P
H
R
K
P
S
S
S
A
S
S
S
S
Site 251
S1629
K
P
H
R
K
P
S
S
S
A
S
S
S
S
S
Site 252
S1630
P
H
R
K
P
S
S
S
A
S
S
S
S
S
S
Site 253
S1632
R
K
P
S
S
S
A
S
S
S
S
S
S
S
S
Site 254
S1633
K
P
S
S
S
A
S
S
S
S
S
S
S
S
F
Site 255
S1634
P
S
S
S
A
S
S
S
S
S
S
S
S
F
S
Site 256
S1635
S
S
S
A
S
S
S
S
S
S
S
S
F
S
L
Site 257
S1636
S
S
A
S
S
S
S
S
S
S
S
F
S
L
D
Site 258
S1637
S
A
S
S
S
S
S
S
S
S
F
S
L
D
A
Site 259
S1638
A
S
S
S
S
S
S
S
S
F
S
L
D
A
A
Site 260
S1639
S
S
S
S
S
S
S
S
F
S
L
D
A
A
G
Site 261
S1641
S
S
S
S
S
S
F
S
L
D
A
A
G
A
S
Site 262
T1651
A
A
G
A
S
L
A
T
L
P
G
G
S
I
L
Site 263
S1663
S
I
L
Q
P
R
P
S
L
P
L
S
S
T
M
Site 264
S1667
P
R
P
S
L
P
L
S
S
T
M
H
L
G
P
Site 265
S1668
R
P
S
L
P
L
S
S
T
M
H
L
G
P
V
Site 266
Y1706
L
G
D
L
C
G
P
Y
Y
P
E
H
C
L
P
Site 267
Y1707
G
D
L
C
G
P
Y
Y
P
E
H
C
L
P
K
Site 268
S1733
E
G
T
C
E
E
A
S
L
P
L
E
R
T
L
Site 269
T1739
A
S
L
P
L
E
R
T
L
K
G
P
E
C
A
Site 270
T1771
A
K
Q
G
P
L
R
T
S
A
R
G
L
S
R
Site 271
S1772
K
Q
G
P
L
R
T
S
A
R
G
L
S
R
R
Site 272
S1777
R
T
S
A
R
G
L
S
R
R
L
Q
S
C
Y
Site 273
S1782
G
L
S
R
R
L
Q
S
C
Y
C
C
D
G
R
Site 274
Y1784
S
R
R
L
Q
S
C
Y
C
C
D
G
R
E
D
Site 275
S1808
K
G
R
K
H
E
C
S
K
E
A
P
A
E
P
Site 276
Y1880
G
C
L
H
T
Y
H
Y
P
C
A
S
D
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation