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Updated November 2019
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Protein Info
Short Name:
ZNF438
Full Name:
Zinc finger protein 438
Alias:
Type:
Mass (Da):
91836
Number AA:
828
UniProt ID:
Q7Z4V0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
Q
N
S
V
S
V
P
P
K
D
E
G
Site 2
S15
P
P
K
D
E
G
E
S
N
I
P
S
G
T
I
Site 3
S19
E
G
E
S
N
I
P
S
G
T
I
Q
S
R
K
Site 4
S32
R
K
G
L
Q
N
K
S
Q
F
R
T
I
A
P
Site 5
T36
Q
N
K
S
Q
F
R
T
I
A
P
K
I
V
P
Site 6
S55
S
R
M
L
P
C
H
S
P
S
R
S
D
Q
V
Site 7
S57
M
L
P
C
H
S
P
S
R
S
D
Q
V
N
L
Site 8
S59
P
C
H
S
P
S
R
S
D
Q
V
N
L
G
P
Site 9
S67
D
Q
V
N
L
G
P
S
I
N
S
K
L
L
G
Site 10
T77
S
K
L
L
G
M
S
T
Q
N
Y
A
L
M
Q
Site 11
S112
P
I
Q
K
P
R
M
S
L
P
E
N
L
K
L
Site 12
Y124
L
K
L
P
I
P
R
Y
Q
P
P
R
N
S
K
Site 13
S130
R
Y
Q
P
P
R
N
S
K
A
S
R
K
K
P
Site 14
S133
P
P
R
N
S
K
A
S
R
K
K
P
I
L
I
Site 15
S160
T
Q
M
C
P
Q
M
S
P
S
P
P
H
H
P
Site 16
S162
M
C
P
Q
M
S
P
S
P
P
H
H
P
E
L
Site 17
Y171
P
H
H
P
E
L
L
Y
K
P
S
P
F
E
E
Site 18
S174
P
E
L
L
Y
K
P
S
P
F
E
E
V
P
S
Site 19
S181
S
P
F
E
E
V
P
S
L
E
Q
A
P
A
S
Site 20
S190
E
Q
A
P
A
S
I
S
T
A
A
L
T
N
G
Site 21
T195
S
I
S
T
A
A
L
T
N
G
S
D
H
G
D
Site 22
S198
T
A
A
L
T
N
G
S
D
H
G
D
L
R
P
Site 23
T208
G
D
L
R
P
P
V
T
N
T
H
G
S
L
N
Site 24
T219
G
S
L
N
P
P
A
T
P
A
S
S
T
P
E
Site 25
S222
N
P
P
A
T
P
A
S
S
T
P
E
E
P
A
Site 26
S223
P
P
A
T
P
A
S
S
T
P
E
E
P
A
K
Site 27
T224
P
A
T
P
A
S
S
T
P
E
E
P
A
K
Q
Site 28
T234
E
P
A
K
Q
D
L
T
A
L
S
G
K
A
H
Site 29
S237
K
Q
D
L
T
A
L
S
G
K
A
H
F
V
S
Site 30
S244
S
G
K
A
H
F
V
S
K
I
T
S
S
K
P
Site 31
T247
A
H
F
V
S
K
I
T
S
S
K
P
S
A
V
Site 32
S248
H
F
V
S
K
I
T
S
S
K
P
S
A
V
A
Site 33
S252
K
I
T
S
S
K
P
S
A
V
A
S
E
K
F
Site 34
S256
S
K
P
S
A
V
A
S
E
K
F
K
E
Q
V
Site 35
T268
E
Q
V
D
L
A
K
T
M
T
N
L
S
P
T
Site 36
Y297
G
K
L
P
I
P
P
Y
S
R
M
K
T
M
E
Site 37
S298
K
L
P
I
P
P
Y
S
R
M
K
T
M
E
V
Site 38
T302
P
P
Y
S
R
M
K
T
M
E
V
Y
K
I
K
Site 39
Y306
R
M
K
T
M
E
V
Y
K
I
K
S
D
A
N
Site 40
S310
M
E
V
Y
K
I
K
S
D
A
N
I
A
G
F
Site 41
T332
D
C
D
K
I
P
S
T
T
E
G
F
N
A
A
Site 42
S352
R
L
P
V
P
Q
V
S
Q
Q
S
A
C
E
S
Site 43
S359
S
Q
Q
S
A
C
E
S
A
F
C
P
P
T
K
Site 44
T365
E
S
A
F
C
P
P
T
K
L
D
L
N
H
K
Site 45
T373
K
L
D
L
N
H
K
T
K
L
N
S
G
A
A
Site 46
Y403
F
Q
G
K
R
R
K
Y
I
I
N
K
C
R
D
Site 47
Y433
K
L
G
T
L
K
K
Y
R
S
I
M
P
K
P
Site 48
S435
G
T
L
K
K
Y
R
S
I
M
P
K
P
I
M
Site 49
S452
P
T
L
A
S
L
A
S
P
T
T
L
Q
S
Q
Site 50
S473
Q
D
V
L
L
N
N
S
L
T
P
K
Y
L
G
Site 51
Y478
N
N
S
L
T
P
K
Y
L
G
C
K
Q
D
N
Site 52
S486
L
G
C
K
Q
D
N
S
S
S
P
K
P
S
S
Site 53
S487
G
C
K
Q
D
N
S
S
S
P
K
P
S
S
V
Site 54
S488
C
K
Q
D
N
S
S
S
P
K
P
S
S
V
F
Site 55
S492
N
S
S
S
P
K
P
S
S
V
F
R
N
G
F
Site 56
S493
S
S
S
P
K
P
S
S
V
F
R
N
G
F
S
Site 57
T528
H
L
R
D
H
M
N
T
H
T
N
R
R
P
Y
Site 58
T530
R
D
H
M
N
T
H
T
N
R
R
P
Y
S
C
Site 59
Y535
T
H
T
N
R
R
P
Y
S
C
R
I
C
R
K
Site 60
S536
H
T
N
R
R
P
Y
S
C
R
I
C
R
K
S
Site 61
S543
S
C
R
I
C
R
K
S
Y
V
R
P
G
S
L
Site 62
Y544
C
R
I
C
R
K
S
Y
V
R
P
G
S
L
S
Site 63
S549
K
S
Y
V
R
P
G
S
L
S
T
H
M
K
L
Site 64
S551
Y
V
R
P
G
S
L
S
T
H
M
K
L
H
H
Site 65
S595
E
V
H
R
V
V
I
S
T
E
P
A
P
S
E
Site 66
S601
I
S
T
E
P
A
P
S
E
L
Q
P
G
D
I
Site 67
S615
I
P
K
N
R
D
M
S
V
R
G
M
E
G
S
Site 68
S622
S
V
R
G
M
E
G
S
L
E
R
E
N
K
S
Site 69
S629
S
L
E
R
E
N
K
S
N
L
E
E
D
F
L
Site 70
T682
E
G
R
L
Q
E
G
T
F
P
G
S
K
G
T
Site 71
S698
E
E
L
V
Q
H
A
S
P
D
W
K
R
H
P
Site 72
S715
G
K
P
E
K
V
H
S
S
S
E
E
S
H
A
Site 73
S716
K
P
E
K
V
H
S
S
S
E
E
S
H
A
C
Site 74
S717
P
E
K
V
H
S
S
S
E
E
S
H
A
C
P
Site 75
S720
V
H
S
S
S
E
E
S
H
A
C
P
R
L
K
Site 76
S748
M
E
N
E
G
P
Q
S
G
T
N
K
P
R
E
Site 77
T756
G
T
N
K
P
R
E
T
C
Q
G
P
E
C
P
Site 78
T767
P
E
C
P
G
L
H
T
F
L
L
W
S
H
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation