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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GDF7
Full Name:
Growth/differentiation factor 7
Alias:
Type:
Mass (Da):
46950
Number AA:
450
UniProt ID:
Q7Z4P5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
A
G
A
G
P
V
R
S
P
G
G
G
G
G
G
Site 2
T52
G
G
G
G
G
G
R
T
L
A
Q
A
A
G
A
Site 3
S79
A
A
R
R
A
A
G
S
G
F
R
N
G
S
V
Site 4
S85
G
S
G
F
R
N
G
S
V
V
P
H
H
F
M
Site 5
Y96
H
H
F
M
M
S
L
Y
R
S
L
A
G
R
A
Site 6
T120
S
G
H
G
R
A
D
T
I
T
G
F
T
D
Q
Site 7
T122
H
G
R
A
D
T
I
T
G
F
T
D
Q
A
T
Site 8
T129
T
G
F
T
D
Q
A
T
Q
D
E
S
A
A
E
Site 9
S133
D
Q
A
T
Q
D
E
S
A
A
E
T
G
Q
S
Site 10
T137
Q
D
E
S
A
A
E
T
G
Q
S
F
L
F
D
Site 11
S140
S
A
A
E
T
G
Q
S
F
L
F
D
V
S
S
Site 12
S166
L
R
V
L
R
R
G
S
P
E
S
G
P
G
S
Site 13
S169
L
R
R
G
S
P
E
S
G
P
G
S
W
T
S
Site 14
S173
S
P
E
S
G
P
G
S
W
T
S
P
P
L
L
Site 15
T175
E
S
G
P
G
S
W
T
S
P
P
L
L
L
L
Site 16
Y196
A
R
A
P
R
L
L
Y
S
R
A
A
E
P
L
Site 17
S197
R
A
P
R
L
L
Y
S
R
A
A
E
P
L
V
Site 18
S243
A
V
A
G
P
V
P
S
P
L
A
L
R
R
L
Site 19
S260
G
W
P
G
G
G
G
S
A
A
E
E
R
A
V
Site 20
S271
E
R
A
V
L
V
V
S
S
R
T
Q
R
K
E
Site 21
T274
V
L
V
V
S
S
R
T
Q
R
K
E
S
L
F
Site 22
S279
S
R
T
Q
R
K
E
S
L
F
R
E
I
R
A
Site 23
T305
E
P
L
P
D
P
G
T
G
T
A
S
P
R
A
Site 24
T307
L
P
D
P
G
T
G
T
A
S
P
R
A
V
I
Site 25
S309
D
P
G
T
G
T
A
S
P
R
A
V
I
G
G
Site 26
T322
G
G
R
R
R
R
R
T
A
L
A
G
T
R
T
Site 27
T329
T
A
L
A
G
T
R
T
S
Q
G
S
G
G
G
Site 28
S330
A
L
A
G
T
R
T
S
Q
G
S
G
G
G
A
Site 29
S333
G
T
R
T
S
Q
G
S
G
G
G
A
G
R
G
Site 30
S347
G
H
G
R
R
G
R
S
R
C
S
R
K
P
L
Site 31
S350
R
R
G
R
S
R
C
S
R
K
P
L
H
V
D
Site 32
Y373
W
I
I
A
P
L
D
Y
E
A
Y
H
C
E
G
Site 33
Y376
A
P
L
D
Y
E
A
Y
H
C
E
G
L
C
D
Site 34
S388
L
C
D
F
P
L
R
S
H
L
E
P
T
N
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation