KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DHX29
Full Name:
ATP-dependent RNA helicase DHX29
Alias:
ATP-dependent RNA helicase DHX29: DEAH box protein 29: Nucleic acid helicase DDXx; DDX29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH box protein 29; Nucleic acid helicase DDXx
Type:
EC 3.6.1.-; Helicase
Mass (Da):
155236
Number AA:
1369
UniProt ID:
Q7Z478
International Prot ID:
IPI00217413
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008026
GO:0003743
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
V
R
A
A
V
S
A
S
R
A
K
S
A
E
A
Site 2
S27
V
S
A
S
R
A
K
S
A
E
A
G
I
A
G
Site 3
S38
G
I
A
G
E
A
Q
S
K
K
P
V
S
R
P
Site 4
S43
A
Q
S
K
K
P
V
S
R
P
A
T
A
A
A
Site 5
Y67
V
K
Q
G
P
K
I
Y
S
F
N
S
T
N
D
Site 6
S68
K
Q
G
P
K
I
Y
S
F
N
S
T
N
D
S
Site 7
S71
P
K
I
Y
S
F
N
S
T
N
D
S
S
G
P
Site 8
T72
K
I
Y
S
F
N
S
T
N
D
S
S
G
P
A
Site 9
S75
S
F
N
S
T
N
D
S
S
G
P
A
N
L
D
Site 10
S116
N
N
D
K
G
M
I
S
G
R
L
T
A
K
K
Site 11
T120
G
M
I
S
G
R
L
T
A
K
K
L
Q
D
L
Site 12
Y128
A
K
K
L
Q
D
L
Y
M
A
L
Q
A
F
S
Site 13
S135
Y
M
A
L
Q
A
F
S
F
K
T
K
D
I
E
Site 14
T146
K
D
I
E
D
A
M
T
N
T
L
L
Y
G
G
Site 15
S167
D
W
L
C
L
N
L
S
D
D
A
L
P
E
G
Site 16
S176
D
A
L
P
E
G
F
S
Q
E
F
E
E
Q
Q
Site 17
S186
F
E
E
Q
Q
P
K
S
R
P
K
F
Q
S
P
Site 18
S192
K
S
R
P
K
F
Q
S
P
Q
I
Q
A
T
I
Site 19
T198
Q
S
P
Q
I
Q
A
T
I
S
P
P
L
Q
P
Site 20
S200
P
Q
I
Q
A
T
I
S
P
P
L
Q
P
K
T
Site 21
T207
S
P
P
L
Q
P
K
T
K
T
Y
E
E
D
P
Site 22
T209
P
L
Q
P
K
T
K
T
Y
E
E
D
P
K
S
Site 23
S216
T
Y
E
E
D
P
K
S
K
P
K
K
E
E
K
Site 24
S251
E
K
N
E
N
S
K
S
L
E
E
E
E
K
F
Site 25
T280
D
A
K
E
Q
A
A
T
F
K
L
E
K
N
K
Site 26
T306
K
F
Q
R
E
M
E
T
L
E
D
H
P
V
F
Site 27
S347
N
F
N
L
F
E
K
S
A
A
A
T
E
E
E
Site 28
Y369
H
D
V
R
N
F
D
Y
T
A
R
S
W
T
G
Site 29
T370
D
V
R
N
F
D
Y
T
A
R
S
W
T
G
K
Site 30
S373
N
F
D
Y
T
A
R
S
W
T
G
K
S
P
K
Site 31
T375
D
Y
T
A
R
S
W
T
G
K
S
P
K
Q
F
Site 32
S378
A
R
S
W
T
G
K
S
P
K
Q
F
L
I
D
Site 33
S394
V
R
K
N
L
P
K
S
P
N
P
S
F
E
K
Site 34
S398
L
P
K
S
P
N
P
S
F
E
K
V
P
V
G
Site 35
S453
Y
R
L
V
K
G
Q
S
V
H
Q
L
L
P
P
Site 36
T461
V
H
Q
L
L
P
P
T
Y
R
D
V
W
L
E
Site 37
Y462
H
Q
L
L
P
P
T
Y
R
D
V
W
L
E
W
Site 38
S470
R
D
V
W
L
E
W
S
D
A
E
K
K
R
E
Site 39
T484
E
E
L
N
K
M
E
T
N
K
P
R
D
L
F
Site 40
S517
S
E
N
K
R
E
N
S
E
D
P
E
E
S
W
Site 41
S523
N
S
E
D
P
E
E
S
W
E
N
L
V
S
D
Site 42
S529
E
S
W
E
N
L
V
S
D
E
D
F
S
A
L
Site 43
S537
D
E
D
F
S
A
L
S
L
E
S
A
N
V
E
Site 44
T559
L
F
R
K
L
Q
S
T
P
K
Y
Q
K
L
L
Site 45
Y562
K
L
Q
S
T
P
K
Y
Q
K
L
L
K
E
R
Site 46
S580
P
V
F
K
H
R
D
S
I
V
E
T
L
K
R
Site 47
T584
H
R
D
S
I
V
E
T
L
K
R
H
R
V
V
Site 48
S602
G
E
T
G
S
G
K
S
T
Q
V
P
H
F
L
Site 49
T603
E
T
G
S
G
K
S
T
Q
V
P
H
F
L
L
Site 50
T628
S
K
C
N
I
V
C
T
Q
P
R
R
I
S
A
Site 51
S634
C
T
Q
P
R
R
I
S
A
V
S
L
A
N
R
Site 52
S637
P
R
R
I
S
A
V
S
L
A
N
R
V
C
D
Site 53
S657
N
G
P
G
G
R
N
S
L
C
G
Y
Q
I
R
Site 54
Y661
G
R
N
S
L
C
G
Y
Q
I
R
M
E
S
R
Site 55
S667
G
Y
Q
I
R
M
E
S
R
A
C
E
S
T
R
Site 56
S672
M
E
S
R
A
C
E
S
T
R
L
L
Y
C
T
Site 57
S708
V
D
E
V
H
E
R
S
V
Q
S
D
F
L
L
Site 58
S739
L
M
S
A
T
V
D
S
E
K
F
S
T
Y
F
Site 59
Y745
D
S
E
K
F
S
T
Y
F
T
H
C
P
I
L
Site 60
T747
E
K
F
S
T
Y
F
T
H
C
P
I
L
R
I
Site 61
S755
H
C
P
I
L
R
I
S
G
R
S
Y
P
V
E
Site 62
S781
G
F
V
L
E
K
D
S
E
Y
C
Q
K
F
L
Site 63
Y783
V
L
E
K
D
S
E
Y
C
Q
K
F
L
E
E
Site 64
T795
L
E
E
E
E
E
V
T
I
N
V
T
S
K
A
Site 65
Y808
K
A
G
G
I
K
K
Y
Q
E
Y
I
P
V
Q
Site 66
Y811
G
I
K
K
Y
Q
E
Y
I
P
V
Q
T
G
A
Site 67
Y826
H
A
D
L
N
P
F
Y
Q
K
Y
S
S
R
T
Site 68
Y829
L
N
P
F
Y
Q
K
Y
S
S
R
T
Q
H
A
Site 69
S831
P
F
Y
Q
K
Y
S
S
R
T
Q
H
A
I
L
Site 70
Y839
R
T
Q
H
A
I
L
Y
M
N
P
H
K
I
N
Site 71
S860
L
L
A
Y
L
D
K
S
P
Q
F
R
N
I
E
Site 72
Y884
L
A
H
I
Q
Q
L
Y
D
L
L
S
N
D
R
Site 73
S888
Q
Q
L
Y
D
L
L
S
N
D
R
R
F
Y
S
Site 74
Y894
L
S
N
D
R
R
F
Y
S
E
R
Y
K
V
I
Site 75
S895
S
N
D
R
R
F
Y
S
E
R
Y
K
V
I
A
Site 76
Y898
R
R
F
Y
S
E
R
Y
K
V
I
A
L
H
S
Site 77
T917
Q
D
Q
A
A
A
F
T
L
P
P
P
G
V
R
Site 78
Y956
G
R
T
K
E
N
K
Y
H
E
S
S
Q
M
S
Site 79
S959
K
E
N
K
Y
H
E
S
S
Q
M
S
S
L
V
Site 80
S960
E
N
K
Y
H
E
S
S
Q
M
S
S
L
V
E
Site 81
S963
Y
H
E
S
S
Q
M
S
S
L
V
E
T
F
V
Site 82
S964
H
E
S
S
Q
M
S
S
L
V
E
T
F
V
S
Site 83
Y994
D
G
F
C
F
R
M
Y
T
R
E
R
F
E
G
Site 84
Y1005
R
F
E
G
F
M
D
Y
S
V
P
E
I
L
R
Site 85
S1029
I
M
K
C
N
L
G
S
P
E
D
F
L
S
K
Site 86
S1035
G
S
P
E
D
F
L
S
K
A
L
D
P
P
Q
Site 87
S1047
P
P
Q
L
Q
V
I
S
N
A
M
N
L
L
R
Site 88
T1067
E
L
N
E
P
K
L
T
P
L
G
Q
H
L
A
Site 89
T1113
T
E
K
S
P
F
T
T
P
I
G
R
K
D
E
Site 90
S1133
S
A
L
A
M
A
D
S
D
H
L
T
I
Y
N
Site 91
T1137
M
A
D
S
D
H
L
T
I
Y
N
A
Y
L
G
Site 92
Y1139
D
S
D
H
L
T
I
Y
N
A
Y
L
G
W
K
Site 93
Y1154
K
A
R
Q
E
G
G
Y
R
S
E
I
T
Y
C
Site 94
S1156
R
Q
E
G
G
Y
R
S
E
I
T
Y
C
R
R
Site 95
T1159
G
G
Y
R
S
E
I
T
Y
C
R
R
N
F
L
Site 96
Y1160
G
Y
R
S
E
I
T
Y
C
R
R
N
F
L
N
Site 97
S1170
R
N
F
L
N
R
T
S
L
L
T
L
E
D
V
Site 98
T1173
L
N
R
T
S
L
L
T
L
E
D
V
K
Q
E
Site 99
S1191
L
V
K
A
A
G
F
S
S
S
T
T
S
T
S
Site 100
S1192
V
K
A
A
G
F
S
S
S
T
T
S
T
S
W
Site 101
S1193
K
A
A
G
F
S
S
S
T
T
S
T
S
W
E
Site 102
T1194
A
A
G
F
S
S
S
T
T
S
T
S
W
E
G
Site 103
T1195
A
G
F
S
S
S
T
T
S
T
S
W
E
G
N
Site 104
S1196
G
F
S
S
S
T
T
S
T
S
W
E
G
N
R
Site 105
T1197
F
S
S
S
T
T
S
T
S
W
E
G
N
R
A
Site 106
S1198
S
S
S
T
T
S
T
S
W
E
G
N
R
A
S
Site 107
S1205
S
W
E
G
N
R
A
S
Q
T
L
S
F
Q
E
Site 108
T1207
E
G
N
R
A
S
Q
T
L
S
F
Q
E
I
A
Site 109
S1209
N
R
A
S
Q
T
L
S
F
Q
E
I
A
L
L
Site 110
S1236
G
K
I
I
Y
T
K
S
V
D
V
T
E
K
L
Site 111
S1259
G
K
A
Q
V
H
P
S
S
V
N
R
D
L
Q
Site 112
S1260
K
A
Q
V
H
P
S
S
V
N
R
D
L
Q
T
Site 113
T1267
S
V
N
R
D
L
Q
T
H
G
W
L
L
Y
Q
Site 114
Y1273
Q
T
H
G
W
L
L
Y
Q
E
K
I
R
Y
A
Site 115
Y1279
L
Y
Q
E
K
I
R
Y
A
R
V
Y
L
R
E
Site 116
Y1283
K
I
R
Y
A
R
V
Y
L
R
E
T
T
L
I
Site 117
S1338
Q
L
R
V
L
I
D
S
V
L
R
K
K
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation