PhosphoNET

           
Protein Info 
   
Short Name:  CSMD2
Full Name:  CUB and sushi domain-containing protein 2
Alias:  CUB and sushi multiple domains protein 2
Type: 
Mass (Da):  380039
Number AA:  3487
UniProt ID:  Q7Z408
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16GPRWQVQSHHPRSAG
Site 2T27RSAGQNCTFQLHGPN
Site 3T36QLHGPNGTVESPGFP
Site 4S39GPNGTVESPGFPYGY
Site 5Y44VESPGFPYGYPNYAN
Site 6Y46SPGFPYGYPNYANCT
Site 7S81EEDFDVLSVFDGPPQ
Site 8T94PQPENLRTRLTGFQL
Site 9T97ENLRTRLTGFQLPAT
Site 10T130SAQGFHATYEVLPSH
Site 11Y131AQGFHATYEVLPSHT
Site 12S136ATYEVLPSHTCGNPG
Site 13S153PNGIQQGSTFNLGDK
Site 14T154NGIQQGSTFNLGDKV
Site 15Y163NLGDKVRYSCNLGFF
Site 16T178LEGHAVLTCHAGSEN
Site 17T188AGSENSATWDFPLPS
Site 18T205ADDACGGTLRGQSGI
Site 19S210GGTLRGQSGIISSPH
Site 20S214RGQSGIISSPHFPSE
Site 21S215GQSGIISSPHFPSEY
Site 22S220ISSPHFPSEYHNNAD
Site 23Y222SPHFPSEYHNNADCT
Site 24Y253DFQLEDGYDFLEVTG
Site 25T259GYDFLEVTGTEGSSL
Site 26S265VTGTEGSSLWFTGAS
Site 27T269EGSSLWFTGASLPAP
Site 28S300NHRQRGFSAQYQVKK
Site 29S313KKQIELKSRGVKLMP
Site 30S321RGVKLMPSKDNSQKT
Site 31S325LMPSKDNSQKTSVLT
Site 32S329KDNSQKTSVLTQVGV
Site 33T332SQKTSVLTQVGVSQG
Site 34S357ERGKRLGSDFRLGSS
Site 35S363GSDFRLGSSVQFTCN
Site 36S364SDFRLGSSVQFTCNE
Site 37T368LGSSVQFTCNEGYDL
Site 38Y373QFTCNEGYDLQGSKR
Site 39S378EGYDLQGSKRITCMK
Site 40T382LQGSKRITCMKVSDM
Site 41S413DAHLRGPSGIITSPN
Site 42T417RGPSGIITSPNFPIQ
Site 43S418GPSGIITSPNFPIQY
Site 44Y425SPNFPIQYDNNAHCV
Site 45Y457EFDLERGYDTLTVGD
Site 46T459DLERGYDTLTVGDGG
Site 47T461ERGYDTLTVGDGGQD
Site 48T473GQDGDQKTVLYILTG
Site 49T500QMWLLFQTDGSGSSL
Site 50S503LLFQTDGSGSSLGFK
Site 51S506QTDGSGSSLGFKASY
Site 52S512SSLGFKASYEEIEQG
Site 53Y513SLGFKASYEEIEQGS
Site 54Y529GDPGIPAYGRREGSR
Site 55S535AYGRREGSRFHHGDT
Site 56T542SRFHHGDTLKFECQP
Site 57S591SPSGVVLSPNYPEDY
Site 58Y594GVVLSPNYPEDYGNH
Site 59Y598SPNYPEDYGNHLHCV
Site 60S649APVLGTFSGNQLPSS
Site 61S655FSGNQLPSSITSSGH
Site 62S656SGNQLPSSITSSGHV
Site 63S659QLPSSITSSGHVARL
Site 64S660LPSSITSSGHVARLE
Site 65T670VARLEFQTDHSTGKR
Site 66S673LEFQTDHSTGKRGFN
Site 67T674EFQTDHSTGKRGFNI
Site 68S706NGKRFGDSLQLGSSI
Site 69S712DSLQLGSSISFLCDE
Site 70T731TQGSETITCVLKEGS
Site 71S760GGHLTSPSGTILSPG
Site 72T762HLTSPSGTILSPGWP
Site 73S765SPSGTILSPGWPGFY
Site 74Y772SPGWPGFYKDALSCA
Site 75T793PGYPIKITFDRFKTE
Site 76T799ITFDRFKTEVNYDTL
Site 77Y803RFKTEVNYDTLEVRD
Site 78T805KTEVNYDTLEVRDGR
Site 79T813LEVRDGRTYSAPLIG
Site 80Y814EVRDGRTYSAPLIGV
Site 81S815VRDGRTYSAPLIGVY
Site 82Y839ISTSNYLYLLFSTDK
Site 83S843NYLYLLFSTDKSHSD
Site 84S847LLFSTDKSHSDIGFQ
Site 85Y857DIGFQLRYETITLQS
Site 86T859GFQLRYETITLQSDH
Site 87T861QLRYETITLQSDHCL
Site 88Y884QRHGNDFYVGALVTF
Site 89Y897TFSCDSGYTLSDGEP
Site 90S900CDSGYTLSDGEPLEC
Site 91S919QWSRALPSCEALCGG
Site 92S937GSSGTILSPGFPDFY
Site 93Y944SPGFPDFYPNNLNCT
Site 94Y977HLESGHDYLLITENG
Site 95T981GHDYLLITENGSFTQ
Site 96S985LLITENGSFTQPLRQ
Site 97T994TQPLRQLTGSRLPAP
Site 98S996PLRQLTGSRLPAPIS
Site 99S1018TAQVRFISDFSMSYE
Site 100S1021VRFISDFSMSYEGFN
Site 101T1030SYEGFNITFSEYDLE
Site 102S1032EGFNITFSEYDLEPC
Site 103Y1047EEPEVPAYSIRKGLQ
Site 104S1048EPEVPAYSIRKGLQF
Site 105Y1069TFSCFPGYRLEGTAR
Site 106T1074PGYRLEGTARITCLG
Site 107T1078LEGTARITCLGGRRR
Site 108S1088GGRRRLWSSPLPRCV
Site 109S1089GRRRLWSSPLPRCVA
Site 110S1101CVAECGNSVTGTQGT
Site 111T1105CGNSVTGTQGTLLSP
Site 112S1111GTQGTLLSPNFPVNY
Site 113S1146KARAFELSEGDVLKV
Site 114Y1154EGDVLKVYDGNNNSA
Site 115S1160VYDGNNNSARLLGVF
Site 116T1176HSEMMGVTLNSTSSS
Site 117T1190SLWLDFITDAENTSK
Site 118S1196ITDAENTSKGFELHF
Site 119T1216IKCEDPGTPKFGYKV
Site 120Y1221PGTPKFGYKVHDEGH
Site 121S1232DEGHFAGSSVSFSCD
Site 122S1233EGHFAGSSVSFSCDP
Site 123S1235HFAGSSVSFSCDPGY
Site 124S1237AGSSVSFSCDPGYSL
Site 125Y1242SFSCDPGYSLRGSEE
Site 126S1243FSCDPGYSLRGSEEL
Site 127S1247PGYSLRGSEELLCLS
Site 128S1254SEELLCLSGERRTWD
Site 129T1259CLSGERRTWDRPLPT
Site 130S1280GTVRGEVSGQVLSPG
Site 131S1285EVSGQVLSPGYPAPY
Site 132Y1288GQVLSPGYPAPYEHN
Site 133Y1292SPGYPAPYEHNLNCI
Site 134T1354LPKDLHSTFNSVVLQ
Site 135S1384FSVSTATSCNDPGIP
Site 136S1395PGIPQNGSRSGDSWE
Site 137S1397IPQNGSRSGDSWEAG
Site 138S1400NGSRSGDSWEAGDST
Site 139S1406DSWEAGDSTVFQCDP
Site 140T1407SWEAGDSTVFQCDPG
Site 141Y1415VFQCDPGYALQGSAE
Site 142S1424LQGSAEISCVKIENR
Site 143S1458GPSGVILSPNYPEPY
Site 144Y1461GVILSPNYPEPYPPG
Site 145Y1465SPNYPEPYPPGKECD
Site 146T1476KECDWKVTVSPDYVI
Site 147Y1496IFNLEPGYDFLHIYD
Site 148Y1502GYDFLHIYDGRDSLS
Site 149S1507HIYDGRDSLSPLIGS
Site 150S1509YDGRDSLSPLIGSFY
Site 151Y1516SPLIGSFYGSQLPGR
Site 152S1526QLPGRIESSSNSLFL
Site 153S1528PGRIESSSNSLFLAF
Site 154S1530RIESSSNSLFLAFRS
Site 155Y1550NAGFVIDYTENPRES
Site 156T1551AGFVIDYTENPRESC
Site 157S1557YTENPRESCFDPGSI
Site 158S1563ESCFDPGSIKNGTRV
Site 159T1568PGSIKNGTRVGSDLK
Site 160S1572KNGTRVGSDLKLGSS
Site 161S1579SDLKLGSSVTYYCHG
Site 162T1581LKLGSSVTYYCHGGY
Site 163Y1582KLGSSVTYYCHGGYE
Site 164Y1583LGSSVTYYCHGGYEV
Site 165Y1588TYYCHGGYEVEGTST
Site 166S1632GSDGVVLSPNYPQNY
Site 167Y1635GVVLSPNYPQNYTSG
Site 168Y1639SPNYPQNYTSGQICL
Site 169S1679VEVHDGHSQHSRLLS
Site 170S1682HDGHSQHSRLLSSLS
Site 171S1686SQHSRLLSSLSGSHT
Site 172S1687QHSRLLSSLSGSHTG
Site 173S1689SRLLSSLSGSHTGES
Site 174S1691LLSSLSGSHTGESLP
Site 175T1693SSLSGSHTGESLPLA
Site 176S1696SGSHTGESLPLATSN
Site 177Y1724ARGFHFVYQAVPRTS
Site 178S1731YQAVPRTSATQCSSV
Site 179T1733AVPRTSATQCSSVPE
Site 180S1736RTSATQCSSVPEPRY
Site 181S1737TSATQCSSVPEPRYG
Site 182Y1743SSVPEPRYGKRLGSD
Site 183S1749RYGKRLGSDFSVGAI
Site 184S1763IVRFECNSGYALQGS
Site 185Y1765RFECNSGYALQGSPE
Site 186S1770SGYALQGSPEIECLP
Site 187T1801VPCGGNLTERRGTIL
Site 188T1806NLTERRGTILSPGFP
Site 189S1809ERRGTILSPGFPEPY
Site 190Y1816SPGFPEPYLNSLNCV
Site 191S1849VTEQNWDSLEVFDGA
Site 192T1861DGADNTVTMLGSFSG
Site 193S1879PALLNSTSNQLYLHF
Site 194Y1883NSTSNQLYLHFYSDI
Site 195Y1887NQLYLHFYSDISVSA
Site 196T1903GFHLEYKTVGLSSCP
Site 197S1907EYKTVGLSSCPEPAV
Site 198T1921VPSNGVKTGERYLVN
Site 199Y1939SFQCEPGYALQGHAH
Site 200Y1959GTVRRWNYPPPLCIA
Site 201S1981EMEGVILSPGFPGNY
Site 202Y1988SPGFPGNYPSNMDCS
Site 203Y2021STEPNHDYIEIRNGP
Site 204S2039SRMMGRFSGSELPSS
Site 205S2045FSGSELPSSLLSTSH
Site 206S2046SGSELPSSLLSTSHE
Site 207S2049ELPSSLLSTSHETTV
Site 208T2050LPSSLLSTSHETTVY
Site 209S2051PSSLLSTSHETTVYF
Site 210T2055LSTSHETTVYFHSDH
Site 211Y2057TSHETTVYFHSDHSQ
Site 212S2063VYFHSDHSQNRPGFK
Site 213Y2073RPGFKLEYQDLTYSH
Site 214T2077KLEYQDLTYSHQISS
Site 215Y2078LEYQDLTYSHQISSF
Site 216S2079EYQDLTYSHQISSFL
Site 217S2083LTYSHQISSFLRGFD
Site 218S2084TYSHQISSFLRGFDL
Site 219S2092FLRGFDLSELERTNS
Site 220T2097DLSELERTNSTPPVA
Site 221S2099SELERTNSTPPVAAS
Site 222T2100ELERTNSTPPVAASY
Site 223S2106STPPVAASYVWDLDP
Site 224Y2107TPPVAASYVWDLDPG
Site 225T2146YNVGQSVTFECLPGY
Site 226Y2153TFECLPGYQLTGHPV
Site 227T2162LTGHPVLTCQHGTNR
Site 228S2188PCGGNITSSNGTVYS
Site 229S2189CGGNITSSNGTVYSP
Site 230T2192NITSSNGTVYSPGFP
Site 231Y2194TSSNGTVYSPGFPSP
Site 232S2195SSNGTVYSPGFPSPY
Site 233S2200VYSPGFPSPYSSSQD
Site 234Y2202SPGFPSPYSSSQDCV
Site 235S2203PGFPSPYSSSQDCVW
Site 236S2204GFPSPYSSSQDCVWL
Site 237S2205FPSPYSSSQDCVWLI
Site 238S2225HGVRLNLSLLQTEPS
Site 239T2237EPSGDFITIWDGPQQ
Site 240T2253APRLGVFTRSMAKKT
Site 241S2255RLGVFTRSMAKKTVQ
Site 242T2260TRSMAKKTVQSSSNQ
Site 243S2265KKTVQSSSNQVLLKF
Site 244Y2341LTCKLGTYLQFEGPP
Site 245S2364TNELLTDSTGVILSQ
Site 246T2365NELLTDSTGVILSQS
Site 247S2370DSTGVILSQSYPGSY
Site 248S2372TGVILSQSYPGSYPQ
Site 249Y2373GVILSQSYPGSYPQF
Site 250S2376LSQSYPGSYPQFQTC
Site 251Y2377SQSYPGSYPQFQTCS
Site 252T2398PDYNISLTVEYFLSE
Site 253Y2401NISLTVEYFLSEKQY
Site 254S2404LTVEYFLSEKQYDEF
Site 255Y2408YFLSEKQYDEFEIFD
Site 256S2418FEIFDGPSGQSPLLK
Site 257S2421FDGPSGQSPLLKALS
Site 258S2443IVTSSSNSVYLRWSS
Site 259Y2445TSSSNSVYLRWSSDH
Site 260S2450SVYLRWSSDHAYNRK
Site 261Y2454RWSSDHAYNRKGFKI
Site 262Y2463RKGFKIRYSAPYCSL
Site 263S2464KGFKIRYSAPYCSLP
Site 264Y2467KIRYSAPYCSLPRAP
Site 265S2469RYSAPYCSLPRAPLH
Site 266T2485FILGQTSTQPGGSIH
Site 267S2490TSTQPGGSIHFGCNA
Site 268Y2499HFGCNAGYRLVGHSM
Site 269Y2516CTRHPQGYHLWSEAI
Site 270Y2555TVGTKAMYSCSEGYH
Site 271S2556VGTKAMYSCSEGYHL
Site 272T2576ATAECLDTGLWSNRN
Site 273S2597PVTCPDVSSISVEHG
Site 274S2598VTCPDVSSISVEHGR
Site 275S2600CPDVSSISVEHGRWR
Site 276Y2614RLIFETQYQFQAQLM
Site 277Y2628MLICDPGYYYTGQRV
Site 278Y2630ICDPGYYYTGQRVIR
Site 279S2645CQANGKWSLGDSTPT
Site 280S2649GKWSLGDSTPTCRII
Site 281T2650KWSLGDSTPTCRIIS
Site 282T2652SLGDSTPTCRIISCG
Site 283T2672PNGHRIGTLSVYGAT
Site 284T2689FSCNSGYTLVGSRVR
Site 285S2693SGYTLVGSRVRECMA
Site 286Y2732GHINGENYSYRGSVV
Site 287Y2734INGENYSYRGSVVYQ
Site 288Y2740SYRGSVVYQCNAGFR
Site 289T2766DHHWSGKTPFCVLVS
Site 290S2779VSCGHPGSPPHSQMS
Site 291S2783HPGSPPHSQMSGDSY
Site 292S2786SPPHSQMSGDSYTVG
Site 293Y2790SQMSGDSYTVGAVVR
Site 294T2791QMSGDSYTVGAVVRY
Site 295T2805YSCIGKRTLVGNSTR
Site 296S2810KRTLVGNSTRMCGLD
Site 297T2811RTLVGNSTRMCGLDG
Site 298S2823LDGHWTGSLPHCSGT
Site 299S2850HGIRLGDSFDPGTVM
Site 300T2855GDSFDPGTVMRFSCE
Site 301S2870AGHVLRGSSERTCQA
Site 302S2871GHVLRGSSERTCQAN
Site 303T2874LRGSSERTCQANGSW
Site 304S2880RTCQANGSWSGSQPE
Site 305S2884ANGSWSGSQPECGVI
Site 306S2892QPECGVISCGNPGTP
Site 307T2898ISCGNPGTPSNARVV
Site 308S2900CGNPGTPSNARVVFS
Site 309S2915DGLVFSSSIVYECRE
Site 310Y2918VFSSSIVYECREGYY
Site 311Y2924VYECREGYYATGLLS
Site 312Y2925YECREGYYATGLLSR
Site 313S2931YYATGLLSRHCSVNG
Site 314S2935GLLSRHCSVNGTWTG
Site 315T2939RHCSVNGTWTGSDPE
Site 316Y2970RLGNDFRYNKTVTYQ
Site 317Y2976RYNKTVTYQCVPGYM
Site 318Y2982TYQCVPGYMMESHRV
Site 319S2990MMESHRVSVLSCTKD
Site 320S2993SHRVSVLSCTKDRTW
Site 321T2995RVSVLSCTKDRTWNG
Site 322T2999LSCTKDRTWNGTKPV
Site 323T3003KDRTWNGTKPVCKAL
Site 324S3026PNGKVVGSDFMWGSS
Site 325Y3036MWGSSVTYACLEGYQ
Site 326S3057FTCEGNGSWTGELPQ
Site 327S3087RREDRGFSYRSSVSF
Site 328Y3088REDRGFSYRSSVSFS
Site 329S3090DRGFSYRSSVSFSCH
Site 330S3091RGFSYRSSVSFSCHP
Site 331S3093FSYRSSVSFSCHPPL
Site 332S3105PPLVLVGSPRRFCQS
Site 333S3112SPRRFCQSDGTWSGT
Site 334T3115RFCQSDGTWSGTQPS
Site 335T3119SDGTWSGTQPSCIDP
Site 336S3122TWSGTQPSCIDPTLT
Site 337S3145QFGIQNNSQGYQVGS
Site 338Y3148IQNNSQGYQVGSTVL
Site 339S3152SQGYQVGSTVLFRCQ
Site 340T3153QGYQVGSTVLFRCQK
Site 341Y3162LFRCQKGYLLQGSTT
Site 342S3167KGYLLQGSTTRTCLP
Site 343T3168GYLLQGSTTRTCLPN
Site 344T3171LQGSTTRTCLPNLTW
Site 345T3177RTCLPNLTWSGTPPD
Site 346T3181PNLTWSGTPPDCVPH
Site 347T3195HHCRQPETPTHANVG
Site 348T3212DLPSMGYTLIYSCQE
Site 349Y3215SMGYTLIYSCQEGFS
Site 350S3222YSCQEGFSLKGGSEH
Site 351S3227GFSLKGGSEHRTCKA
Site 352T3231KGGSEHRTCKADGSW
Site 353S3237RTCKADGSWTGKPPI
Site 354S3251ICLEVRPSGRPINTA
Site 355T3257PSGRPINTAREPPLT
Site 356T3264TAREPPLTQALIPGD
Site 357Y3283NSLWKGAYEYQGKKQ
Site 358S3361WALDGHVSSESSGAT
Site 359S3362ALDGHVSSESSGATF
Site 360S3364DGHVSSESSGATFIY
Site 361S3365GHVSSESSGATFIYQ
Site 362T3368SSESSGATFIYQGSV
Site 363Y3371SSGATFIYQGSVKGQ
Site 364S3374ATFIYQGSVKGQGFG
Site 365S3395LDLRLLESDPESIGR
Site 366S3399LLESDPESIGRHFAS
Site 367S3406SIGRHFASNSSSVAA
Site 368Y3432AGFVLYLYKHRRRPK
Site 369T3456ENTNVRATFENPMYD
Site 370Y3462ATFENPMYDRNIQPT
Site 371T3469YDRNIQPTDIMASEA
Site 372S3474QPTDIMASEAEFTVS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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