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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMC7
Full Name:
Transmembrane channel-like protein 7
Alias:
FLJ21240; transmembrane channel-like 7
Type:
Membrane, Integral membrane protein
Mass (Da):
83502
Number AA:
723
UniProt ID:
Q7Z402
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
E
S
S
G
S
A
L
Q
P
G
R
P
Site 2
S15
A
L
Q
P
G
R
P
S
R
Q
P
A
V
H
P
Site 3
S26
A
V
H
P
E
N
L
S
L
D
S
S
C
F
S
Site 4
S29
P
E
N
L
S
L
D
S
S
C
F
S
S
P
P
Site 5
S30
E
N
L
S
L
D
S
S
C
F
S
S
P
P
V
Site 6
S34
L
D
S
S
C
F
S
S
P
P
V
N
F
L
Q
Site 7
S45
N
F
L
Q
E
L
P
S
Y
R
S
I
A
R
R
Site 8
Y46
F
L
Q
E
L
P
S
Y
R
S
I
A
R
R
R
Site 9
S48
Q
E
L
P
S
Y
R
S
I
A
R
R
R
T
T
Site 10
T54
R
S
I
A
R
R
R
T
T
V
H
S
R
D
K
Site 11
T55
S
I
A
R
R
R
T
T
V
H
S
R
D
K
Q
Site 12
S58
R
R
R
T
T
V
H
S
R
D
K
Q
S
G
T
Site 13
T65
S
R
D
K
Q
S
G
T
L
L
K
P
T
D
S
Site 14
T70
S
G
T
L
L
K
P
T
D
S
Y
S
S
Q
L
Site 15
S72
T
L
L
K
P
T
D
S
Y
S
S
Q
L
E
D
Site 16
Y73
L
L
K
P
T
D
S
Y
S
S
Q
L
E
D
R
Site 17
S74
L
K
P
T
D
S
Y
S
S
Q
L
E
D
R
I
Site 18
S75
K
P
T
D
S
Y
S
S
Q
L
E
D
R
I
A
Site 19
S86
D
R
I
A
E
N
L
S
S
H
S
L
R
N
Y
Site 20
S87
R
I
A
E
N
L
S
S
H
S
L
R
N
Y
A
Site 21
S89
A
E
N
L
S
S
H
S
L
R
N
Y
A
L
N
Site 22
Y93
S
S
H
S
L
R
N
Y
A
L
N
I
S
E
K
Site 23
S98
R
N
Y
A
L
N
I
S
E
K
R
R
L
R
D
Site 24
T109
R
L
R
D
I
Q
E
T
Q
M
K
Y
L
S
E
Site 25
Y123
E
W
D
Q
W
K
R
Y
S
S
K
S
W
K
R
Site 26
S124
W
D
Q
W
K
R
Y
S
S
K
S
W
K
R
F
Site 27
S125
D
Q
W
K
R
Y
S
S
K
S
W
K
R
F
L
Site 28
S127
W
K
R
Y
S
S
K
S
W
K
R
F
L
E
K
Site 29
T139
L
E
K
A
R
E
M
T
T
H
L
E
L
W
R
Site 30
S151
L
W
R
E
D
I
R
S
I
E
G
K
F
G
T
Site 31
T158
S
I
E
G
K
F
G
T
G
I
Q
S
Y
F
S
Site 32
T214
K
D
M
D
K
Q
C
T
V
Y
P
V
S
S
S
Site 33
Y216
M
D
K
Q
C
T
V
Y
P
V
S
S
S
G
L
Site 34
T243
G
T
G
F
L
E
E
T
S
L
F
Y
G
H
Y
Site 35
S244
T
G
F
L
E
E
T
S
L
F
Y
G
H
Y
T
Site 36
S298
F
K
I
N
L
I
R
S
E
E
H
F
Q
S
Y
Site 37
Y305
S
E
E
H
F
Q
S
Y
C
N
K
I
F
A
G
Site 38
S329
M
A
D
L
K
H
S
S
L
R
Y
E
L
R
A
Site 39
S352
Q
K
I
A
E
R
T
S
E
E
T
I
R
I
Y
Site 40
T355
A
E
R
T
S
E
E
T
I
R
I
Y
S
L
R
Site 41
Y359
S
E
E
T
I
R
I
Y
S
L
R
L
F
L
N
Site 42
Y378
A
V
L
G
A
C
F
Y
A
I
Y
V
A
T
V
Site 43
Y381
G
A
C
F
Y
A
I
Y
V
A
T
V
F
S
Q
Site 44
Y431
I
F
A
K
I
I
R
Y
E
D
Y
S
P
G
F
Site 45
Y434
K
I
I
R
Y
E
D
Y
S
P
G
F
E
I
R
Site 46
S435
I
I
R
Y
E
D
Y
S
P
G
F
E
I
R
L
Site 47
S468
T
L
G
S
K
I
T
S
C
D
D
D
T
C
D
Site 48
Y585
V
K
E
W
S
L
L
Y
T
C
R
P
S
P
R
Site 49
T586
K
E
W
S
L
L
Y
T
C
R
P
S
P
R
P
Site 50
S590
L
L
Y
T
C
R
P
S
P
R
P
F
R
A
S
Site 51
S597
S
P
R
P
F
R
A
S
N
S
N
F
F
F
L
Site 52
S628
S
I
S
R
I
P
S
S
K
A
C
G
P
F
T
Site 53
T647
T
W
E
V
I
P
K
T
V
S
T
F
P
S
S
Site 54
S649
E
V
I
P
K
T
V
S
T
F
P
S
S
L
Q
Site 55
S653
K
T
V
S
T
F
P
S
S
L
Q
S
F
I
H
Site 56
S701
I
Q
L
R
E
Q
L
S
L
E
S
R
D
K
C
Site 57
Y709
L
E
S
R
D
K
C
Y
L
I
Q
K
L
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation