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Updated November 2019
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Protein Info
Short Name:
DENND4A
Full Name:
C-myc promoter-binding protein
Alias:
DENN domain-containing protein 4A; DENN/MADD domain containing 4A; IRLB; MYCPBP; MYCPP
Type:
Nucleus protein; Transcription protein
Mass (Da):
209244
Number AA:
1863
UniProt ID:
Q7Z401
International Prot ID:
IPI00396063
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
V
A
G
L
T
D
V
S
K
P
L
E
E
E
I
Site 2
T46
A
K
P
K
E
P
I
T
D
V
S
V
I
I
K
Site 3
Y63
G
E
E
V
P
Q
D
Y
I
C
I
D
V
T
P
Site 4
S81
S
A
D
L
N
N
G
S
L
V
G
P
Q
I
Y
Site 5
Y88
S
L
V
G
P
Q
I
Y
L
C
Y
R
R
G
R
Site 6
Y91
G
P
Q
I
Y
L
C
Y
R
R
G
R
D
K
P
Site 7
T101
G
R
D
K
P
P
L
T
D
L
G
V
L
Y
D
Site 8
Y107
L
T
D
L
G
V
L
Y
D
W
K
E
R
L
K
Site 9
S122
Q
G
C
E
I
I
Q
S
T
P
Y
G
R
P
A
Site 10
T123
G
C
E
I
I
Q
S
T
P
Y
G
R
P
A
N
Site 11
Y125
E
I
I
Q
S
T
P
Y
G
R
P
A
N
I
S
Site 12
S132
Y
G
R
P
A
N
I
S
G
S
T
S
S
Q
R
Site 13
S134
R
P
A
N
I
S
G
S
T
S
S
Q
R
I
Y
Site 14
S136
A
N
I
S
G
S
T
S
S
Q
R
I
Y
I
T
Site 15
S137
N
I
S
G
S
T
S
S
Q
R
I
Y
I
T
Y
Site 16
Y141
S
T
S
S
Q
R
I
Y
I
T
Y
R
R
A
S
Site 17
T143
S
S
Q
R
I
Y
I
T
Y
R
R
A
S
E
N
Site 18
Y144
S
Q
R
I
Y
I
T
Y
R
R
A
S
E
N
M
Site 19
T152
R
R
A
S
E
N
M
T
Q
N
T
L
A
V
T
Site 20
T155
S
E
N
M
T
Q
N
T
L
A
V
T
D
I
C
Site 21
S167
D
I
C
I
I
I
P
S
K
G
E
S
P
P
H
Site 22
S171
I
I
P
S
K
G
E
S
P
P
H
T
F
C
K
Site 23
T175
K
G
E
S
P
P
H
T
F
C
K
V
D
K
N
Site 24
S186
V
D
K
N
L
N
N
S
M
W
G
S
A
V
Y
Site 25
S190
L
N
N
S
M
W
G
S
A
V
Y
L
C
Y
K
Site 26
S199
V
Y
L
C
Y
K
K
S
V
A
K
T
N
T
V
Site 27
T203
Y
K
K
S
V
A
K
T
N
T
V
S
Y
K
A
Site 28
T205
K
S
V
A
K
T
N
T
V
S
Y
K
A
G
L
Site 29
Y221
C
R
Y
P
Q
E
D
Y
E
S
F
S
L
P
E
Site 30
S223
Y
P
Q
E
D
Y
E
S
F
S
L
P
E
S
V
Site 31
S225
Q
E
D
Y
E
S
F
S
L
P
E
S
V
P
L
Site 32
S246
A
T
I
E
C
W
P
S
N
S
K
Y
P
L
P
Site 33
Y250
C
W
P
S
N
S
K
Y
P
L
P
V
F
S
T
Site 34
Y276
Y
G
A
A
I
Q
F
Y
E
P
Y
S
E
E
N
Site 35
S280
I
Q
F
Y
E
P
Y
S
E
E
N
L
T
E
K
Site 36
T285
P
Y
S
E
E
N
L
T
E
K
Q
R
L
L
L
Site 37
T295
Q
R
L
L
L
G
L
T
S
A
D
G
K
S
D
Site 38
S296
R
L
L
L
G
L
T
S
A
D
G
K
S
D
S
Site 39
S301
L
T
S
A
D
G
K
S
D
S
S
K
T
I
H
Site 40
S303
S
A
D
G
K
S
D
S
S
K
T
I
H
T
N
Site 41
S304
A
D
G
K
S
D
S
S
K
T
I
H
T
N
K
Site 42
Y333
R
K
F
L
T
F
L
Y
R
Y
S
I
S
G
P
Site 43
S360
M
H
K
V
P
F
P
S
P
Q
R
P
R
I
L
Site 44
S379
P
H
D
N
L
I
L
S
Q
P
V
S
S
P
L
Site 45
T395
L
S
G
G
K
F
S
T
L
L
Q
N
L
G
P
Site 46
Y474
I
V
G
I
D
S
R
Y
F
D
L
Y
D
P
P
Site 47
Y478
D
S
R
Y
F
D
L
Y
D
P
P
P
D
V
S
Site 48
S485
Y
D
P
P
P
D
V
S
C
V
D
V
D
T
N
Site 49
T493
C
V
D
V
D
T
N
T
I
S
Q
I
G
D
K
Site 50
S495
D
V
D
T
N
T
I
S
Q
I
G
D
K
K
N
Site 51
T519
P
C
K
N
L
M
N
T
L
N
N
L
H
Q
Q
Site 52
Y547
M
D
L
A
I
N
D
Y
D
F
N
S
G
K
R
Site 53
S579
S
I
L
K
G
Y
R
S
Y
L
R
P
I
T
Q
Site 54
Y580
I
L
K
G
Y
R
S
Y
L
R
P
I
T
Q
A
Site 55
T585
R
S
Y
L
R
P
I
T
Q
A
P
S
E
T
A
Site 56
S589
R
P
I
T
Q
A
P
S
E
T
A
T
D
A
A
Site 57
T593
Q
A
P
S
E
T
A
T
D
A
A
S
L
F
A
Site 58
S607
A
L
Q
A
F
L
R
S
R
D
R
S
H
Q
K
Site 59
S611
F
L
R
S
R
D
R
S
H
Q
K
F
Y
N
M
Site 60
S633
I
R
F
I
E
E
C
S
F
V
S
D
K
D
A
Site 61
S657
D
K
V
D
M
D
K
S
G
E
V
R
L
I
E
Site 62
S668
R
L
I
E
L
D
E
S
F
K
S
E
H
T
V
Site 63
S671
E
L
D
E
S
F
K
S
E
H
T
V
F
V
T
Site 64
T674
E
S
F
K
S
E
H
T
V
F
V
T
P
P
E
Site 65
T678
S
E
H
T
V
F
V
T
P
P
E
I
P
H
L
Site 66
S696
E
E
P
P
L
Q
Y
S
Y
N
G
F
P
V
L
Site 67
S724
A
K
K
N
K
L
P
S
K
S
S
S
P
N
S
Site 68
S726
K
N
K
L
P
S
K
S
S
S
P
N
S
P
L
Site 69
S727
N
K
L
P
S
K
S
S
S
P
N
S
P
L
P
Site 70
S728
K
L
P
S
K
S
S
S
P
N
S
P
L
P
M
Site 71
S731
S
K
S
S
S
P
N
S
P
L
P
M
F
R
R
Site 72
T739
P
L
P
M
F
R
R
T
K
Q
E
I
K
S
A
Site 73
S745
R
T
K
Q
E
I
K
S
A
H
K
I
A
K
R
Site 74
S755
K
I
A
K
R
Y
S
S
I
P
Q
M
W
S
R
Site 75
S785
A
Y
V
K
V
C
H
S
K
V
R
A
L
K
T
Site 76
T792
S
K
V
R
A
L
K
T
A
Y
D
V
L
K
K
Site 77
S802
D
V
L
K
K
M
Q
S
K
K
M
D
P
P
D
Site 78
Y823
L
M
Q
L
C
G
Q
Y
D
Q
P
V
L
A
V
Site 79
S858
Y
N
K
A
V
L
E
S
T
W
P
S
R
S
R
Site 80
T859
N
K
A
V
L
E
S
T
W
P
S
R
S
R
S
Site 81
S862
V
L
E
S
T
W
P
S
R
S
R
S
G
Y
F
Site 82
S864
E
S
T
W
P
S
R
S
R
S
G
Y
F
L
W
Site 83
S866
T
W
P
S
R
S
R
S
G
Y
F
L
W
T
K
Site 84
Y868
P
S
R
S
R
S
G
Y
F
L
W
T
K
V
R
Site 85
S895
L
K
K
H
A
H
L
S
Q
T
T
L
S
G
G
Site 86
S900
H
L
S
Q
T
T
L
S
G
G
Q
S
D
L
G
Site 87
S904
T
T
L
S
G
G
Q
S
D
L
G
Y
N
S
L
Site 88
Y908
G
G
Q
S
D
L
G
Y
N
S
L
S
K
D
E
Site 89
S910
Q
S
D
L
G
Y
N
S
L
S
K
D
E
V
R
Site 90
S912
D
L
G
Y
N
S
L
S
K
D
E
V
R
R
G
Site 91
T921
D
E
V
R
R
G
D
T
S
T
E
D
I
Q
E
Site 92
S922
E
V
R
R
G
D
T
S
T
E
D
I
Q
E
E
Site 93
T923
V
R
R
G
D
T
S
T
E
D
I
Q
E
E
K
Site 94
S935
E
E
K
D
K
K
G
S
D
C
S
S
L
S
E
Site 95
S938
D
K
K
G
S
D
C
S
S
L
S
E
S
E
S
Site 96
S939
K
K
G
S
D
C
S
S
L
S
E
S
E
S
T
Site 97
S941
G
S
D
C
S
S
L
S
E
S
E
S
T
K
G
Site 98
S943
D
C
S
S
L
S
E
S
E
S
T
K
G
S
A
Site 99
S945
S
S
L
S
E
S
E
S
T
K
G
S
A
D
C
Site 100
S949
E
S
E
S
T
K
G
S
A
D
C
L
P
K
L
Site 101
S957
A
D
C
L
P
K
L
S
Y
Q
N
S
S
S
I
Site 102
Y958
D
C
L
P
K
L
S
Y
Q
N
S
S
S
I
V
Site 103
S961
P
K
L
S
Y
Q
N
S
S
S
I
V
R
L
T
Site 104
S963
L
S
Y
Q
N
S
S
S
I
V
R
L
T
G
T
Site 105
T968
S
S
S
I
V
R
L
T
G
T
S
N
N
S
A
Site 106
T970
S
I
V
R
L
T
G
T
S
N
N
S
A
G
K
Site 107
S971
I
V
R
L
T
G
T
S
N
N
S
A
G
K
I
Site 108
S974
L
T
G
T
S
N
N
S
A
G
K
I
S
G
E
Site 109
S982
A
G
K
I
S
G
E
S
M
E
S
T
P
E
L
Site 110
T986
S
G
E
S
M
E
S
T
P
E
L
L
L
I
S
Site 111
S994
P
E
L
L
L
I
S
S
L
E
D
T
N
E
T
Site 112
T998
L
I
S
S
L
E
D
T
N
E
T
R
N
I
Q
Site 113
S1015
C
F
R
K
R
H
K
S
D
N
E
T
N
L
Q
Site 114
T1019
R
H
K
S
D
N
E
T
N
L
Q
Q
Q
V
V
Site 115
S1035
G
N
R
N
R
N
L
S
G
G
V
L
M
G
F
Site 116
T1052
N
R
I
N
Q
E
A
T
P
G
D
I
V
E
K
Site 117
S1068
G
A
D
A
K
I
L
S
N
V
I
S
K
S
T
Site 118
S1072
K
I
L
S
N
V
I
S
K
S
T
R
P
N
T
Site 119
S1074
L
S
N
V
I
S
K
S
T
R
P
N
T
L
D
Site 120
T1079
S
K
S
T
R
P
N
T
L
D
I
G
K
P
P
Site 121
S1089
I
G
K
P
P
L
R
S
K
R
D
S
L
E
K
Site 122
S1093
P
L
R
S
K
R
D
S
L
E
K
E
S
S
D
Site 123
S1098
R
D
S
L
E
K
E
S
S
D
D
D
T
P
F
Site 124
S1099
D
S
L
E
K
E
S
S
D
D
D
T
P
F
D
Site 125
T1103
K
E
S
S
D
D
D
T
P
F
D
G
S
N
Y
Site 126
Y1110
T
P
F
D
G
S
N
Y
L
A
D
K
V
D
S
Site 127
S1128
F
D
L
E
D
L
D
S
E
T
D
V
S
K
A
Site 128
T1130
L
E
D
L
D
S
E
T
D
V
S
K
A
G
C
Site 129
S1133
L
D
S
E
T
D
V
S
K
A
G
C
V
A
T
Site 130
T1140
S
K
A
G
C
V
A
T
Q
N
P
K
R
I
Q
Site 131
S1151
K
R
I
Q
R
M
N
S
S
F
S
V
K
P
F
Site 132
S1152
R
I
Q
R
M
N
S
S
F
S
V
K
P
F
E
Site 133
S1154
Q
R
M
N
S
S
F
S
V
K
P
F
E
K
T
Site 134
T1161
S
V
K
P
F
E
K
T
D
V
A
T
G
F
D
Site 135
S1192
E
E
E
D
E
D
D
S
K
S
I
S
T
P
S
Site 136
S1194
E
D
E
D
D
S
K
S
I
S
T
P
S
A
R
Site 137
S1196
E
D
D
S
K
S
I
S
T
P
S
A
R
R
D
Site 138
T1197
D
D
S
K
S
I
S
T
P
S
A
R
R
D
L
Site 139
S1199
S
K
S
I
S
T
P
S
A
R
R
D
L
A
E
Site 140
Y1211
L
A
E
E
I
V
M
Y
M
N
N
M
S
S
P
Site 141
S1217
M
Y
M
N
N
M
S
S
P
L
T
S
R
T
P
Site 142
T1220
N
N
M
S
S
P
L
T
S
R
T
P
S
I
D
Site 143
S1221
N
M
S
S
P
L
T
S
R
T
P
S
I
D
L
Site 144
T1223
S
S
P
L
T
S
R
T
P
S
I
D
L
Q
R
Site 145
S1225
P
L
T
S
R
T
P
S
I
D
L
Q
R
A
C
Site 146
S1240
D
D
K
L
N
K
K
S
P
P
L
V
K
A
C
Site 147
S1250
L
V
K
A
C
R
R
S
S
L
P
P
N
S
P
Site 148
S1251
V
K
A
C
R
R
S
S
L
P
P
N
S
P
K
Site 149
S1256
R
S
S
L
P
P
N
S
P
K
P
V
R
L
T
Site 150
T1263
S
P
K
P
V
R
L
T
K
S
K
S
Y
T
K
Site 151
S1265
K
P
V
R
L
T
K
S
K
S
Y
T
K
S
E
Site 152
S1267
V
R
L
T
K
S
K
S
Y
T
K
S
E
E
K
Site 153
T1269
L
T
K
S
K
S
Y
T
K
S
E
E
K
P
R
Site 154
S1271
K
S
K
S
Y
T
K
S
E
E
K
P
R
D
R
Site 155
S1281
K
P
R
D
R
L
W
S
S
P
A
F
S
P
T
Site 156
S1282
P
R
D
R
L
W
S
S
P
A
F
S
P
T
C
Site 157
S1286
L
W
S
S
P
A
F
S
P
T
C
P
F
R
E
Site 158
T1288
S
S
P
A
F
S
P
T
C
P
F
R
E
E
S
Site 159
S1295
T
C
P
F
R
E
E
S
Q
D
T
L
T
H
S
Site 160
T1298
F
R
E
E
S
Q
D
T
L
T
H
S
S
P
S
Site 161
T1300
E
E
S
Q
D
T
L
T
H
S
S
P
S
F
N
Site 162
S1302
S
Q
D
T
L
T
H
S
S
P
S
F
N
L
D
Site 163
S1303
Q
D
T
L
T
H
S
S
P
S
F
N
L
D
T
Site 164
S1305
T
L
T
H
S
S
P
S
F
N
L
D
T
L
L
Site 165
S1322
K
L
D
V
L
R
N
S
M
F
T
A
G
K
G
Site 166
S1335
K
G
V
A
E
K
A
S
K
W
Y
S
R
F
T
Site 167
Y1338
A
E
K
A
S
K
W
Y
S
R
F
T
M
Y
T
Site 168
T1342
S
K
W
Y
S
R
F
T
M
Y
T
T
S
S
K
Site 169
Y1344
W
Y
S
R
F
T
M
Y
T
T
S
S
K
D
Q
Site 170
T1345
Y
S
R
F
T
M
Y
T
T
S
S
K
D
Q
S
Site 171
S1347
R
F
T
M
Y
T
T
S
S
K
D
Q
S
S
D
Site 172
S1348
F
T
M
Y
T
T
S
S
K
D
Q
S
S
D
R
Site 173
S1352
T
T
S
S
K
D
Q
S
S
D
R
T
S
L
S
Site 174
S1353
T
S
S
K
D
Q
S
S
D
R
T
S
L
S
S
Site 175
T1356
K
D
Q
S
S
D
R
T
S
L
S
S
V
G
A
Site 176
S1357
D
Q
S
S
D
R
T
S
L
S
S
V
G
A
Q
Site 177
S1359
S
S
D
R
T
S
L
S
S
V
G
A
Q
D
S
Site 178
S1360
S
D
R
T
S
L
S
S
V
G
A
Q
D
S
E
Site 179
S1366
S
S
V
G
A
Q
D
S
E
S
T
S
L
T
D
Site 180
S1368
V
G
A
Q
D
S
E
S
T
S
L
T
D
E
D
Site 181
S1370
A
Q
D
S
E
S
T
S
L
T
D
E
D
V
C
Site 182
T1372
D
S
E
S
T
S
L
T
D
E
D
V
C
H
E
Site 183
S1385
H
E
L
E
G
P
I
S
S
Q
E
T
S
A
T
Site 184
S1386
E
L
E
G
P
I
S
S
Q
E
T
S
A
T
S
Site 185
T1389
G
P
I
S
S
Q
E
T
S
A
T
S
G
T
K
Site 186
S1390
P
I
S
S
Q
E
T
S
A
T
S
G
T
K
R
Site 187
T1392
S
S
Q
E
T
S
A
T
S
G
T
K
R
I
D
Site 188
S1401
G
T
K
R
I
D
L
S
R
I
S
L
E
S
S
Site 189
S1404
R
I
D
L
S
R
I
S
L
E
S
S
A
S
L
Site 190
S1407
L
S
R
I
S
L
E
S
S
A
S
L
E
G
S
Site 191
S1408
S
R
I
S
L
E
S
S
A
S
L
E
G
S
L
Site 192
S1410
I
S
L
E
S
S
A
S
L
E
G
S
L
S
K
Site 193
S1414
S
S
A
S
L
E
G
S
L
S
K
F
A
L
P
Site 194
S1416
A
S
L
E
G
S
L
S
K
F
A
L
P
G
K
Site 195
S1424
K
F
A
L
P
G
K
S
E
V
T
S
S
F
N
Site 196
S1428
P
G
K
S
E
V
T
S
S
F
N
A
S
N
T
Site 197
S1429
G
K
S
E
V
T
S
S
F
N
A
S
N
T
N
Site 198
S1433
V
T
S
S
F
N
A
S
N
T
N
I
F
Q
N
Site 199
Y1504
D
L
R
R
P
G
R
Y
F
L
K
S
S
P
S
Site 200
S1508
P
G
R
Y
F
L
K
S
S
P
S
T
E
N
M
Site 201
S1509
G
R
Y
F
L
K
S
S
P
S
T
E
N
M
H
Site 202
S1511
Y
F
L
K
S
S
P
S
T
E
N
M
H
F
P
Site 203
T1512
F
L
K
S
S
P
S
T
E
N
M
H
F
P
S
Site 204
S1519
T
E
N
M
H
F
P
S
S
I
S
S
Q
T
R
Site 205
S1520
E
N
M
H
F
P
S
S
I
S
S
Q
T
R
Q
Site 206
S1523
H
F
P
S
S
I
S
S
Q
T
R
Q
S
C
I
Site 207
S1528
I
S
S
Q
T
R
Q
S
C
I
S
T
S
A
S
Site 208
S1531
Q
T
R
Q
S
C
I
S
T
S
A
S
G
L
D
Site 209
T1532
T
R
Q
S
C
I
S
T
S
A
S
G
L
D
T
Site 210
S1533
R
Q
S
C
I
S
T
S
A
S
G
L
D
T
S
Site 211
T1539
T
S
A
S
G
L
D
T
S
A
L
S
V
Q
G
Site 212
S1540
S
A
S
G
L
D
T
S
A
L
S
V
Q
G
N
Site 213
S1552
Q
G
N
F
D
L
N
S
K
S
K
L
Q
E
N
Site 214
S1554
N
F
D
L
N
S
K
S
K
L
Q
E
N
F
C
Site 215
T1562
K
L
Q
E
N
F
C
T
R
S
I
Q
I
P
A
Site 216
S1572
I
Q
I
P
A
N
R
S
K
T
A
M
S
K
C
Site 217
T1574
I
P
A
N
R
S
K
T
A
M
S
K
C
P
I
Site 218
S1587
P
I
F
P
M
A
R
S
I
S
T
S
G
P
L
Site 219
S1589
F
P
M
A
R
S
I
S
T
S
G
P
L
D
K
Site 220
T1590
P
M
A
R
S
I
S
T
S
G
P
L
D
K
E
Site 221
S1591
M
A
R
S
I
S
T
S
G
P
L
D
K
E
D
Site 222
T1599
G
P
L
D
K
E
D
T
G
R
Q
K
L
I
S
Site 223
S1606
T
G
R
Q
K
L
I
S
T
G
S
L
P
A
T
Site 224
S1609
Q
K
L
I
S
T
G
S
L
P
A
T
L
Q
G
Site 225
T1613
S
T
G
S
L
P
A
T
L
Q
G
A
T
D
S
Site 226
S1620
T
L
Q
G
A
T
D
S
L
G
L
E
W
H
L
Site 227
S1629
G
L
E
W
H
L
P
S
P
D
P
V
T
V
P
Site 228
S1649
T
G
R
Q
K
L
I
S
T
G
S
L
P
A
T
Site 229
T1660
N
E
G
D
H
A
I
T
V
A
D
F
V
D
H
Site 230
S1694
N
L
P
G
L
I
L
S
S
E
H
C
N
K
Y
Site 231
Y1701
S
S
E
H
C
N
K
Y
S
K
I
P
R
H
C
Site 232
S1710
K
I
P
R
H
C
M
S
E
D
S
K
Y
V
L
Site 233
Y1736
Q
D
P
G
Q
P
L
Y
I
L
W
N
A
H
T
Site 234
S1755
M
V
H
L
L
Q
K
S
D
N
S
F
N
Q
E
Site 235
S1758
L
L
Q
K
S
D
N
S
F
N
Q
E
L
L
K
Site 236
S1766
F
N
Q
E
L
L
K
S
M
V
K
S
I
K
M
Site 237
Y1777
S
I
K
M
N
D
V
Y
G
P
M
S
Q
I
L
Site 238
S1781
N
D
V
Y
G
P
M
S
Q
I
L
E
T
L
N
Site 239
T1786
P
M
S
Q
I
L
E
T
L
N
K
C
P
H
F
Site 240
S1798
P
H
F
K
R
Q
R
S
L
Y
R
E
I
L
F
Site 241
Y1800
F
K
R
Q
R
S
L
Y
R
E
I
L
F
L
S
Site 242
Y1825
I
D
A
F
D
K
E
Y
K
M
A
Y
D
R
L
Site 243
Y1829
D
K
E
Y
K
M
A
Y
D
R
L
T
P
S
Q
Site 244
T1833
K
M
A
Y
D
R
L
T
P
S
Q
V
K
S
T
Site 245
S1835
A
Y
D
R
L
T
P
S
Q
V
K
S
T
H
N
Site 246
S1839
L
T
P
S
Q
V
K
S
T
H
N
C
D
R
P
Site 247
T1849
N
C
D
R
P
P
S
T
G
V
M
E
C
R
K
Site 248
T1857
G
V
M
E
C
R
K
T
F
G
E
P
Y
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation