KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
POGZ
Full Name:
Pogo transposable element with ZNF domain
Alias:
KIAA0461; Nbla00003; Putative protein product of Nbla00003; SUHW5; Suppressor of hairy wing 5; Zinc finger protein 280E; ZNF280E; ZNF635m
Type:
Transcription factor
Mass (Da):
155344
Number AA:
1410
UniProt ID:
Q7Z3K3
International Prot ID:
IPI00410717
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0009889
GO:0010468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
L
E
P
W
Q
K
I
S
D
V
I
E
D
S
V
Site 2
S28
I
S
D
V
I
E
D
S
V
V
E
D
Y
N
S
Site 3
Y33
E
D
S
V
V
E
D
Y
N
S
V
D
K
T
T
Site 4
S35
S
V
V
E
D
Y
N
S
V
D
K
T
T
T
V
Site 5
T39
D
Y
N
S
V
D
K
T
T
T
V
S
V
S
Q
Site 6
T41
N
S
V
D
K
T
T
T
V
S
V
S
Q
Q
P
Site 7
S43
V
D
K
T
T
T
V
S
V
S
Q
Q
P
V
S
Site 8
S45
K
T
T
T
V
S
V
S
Q
Q
P
V
S
A
P
Site 9
S68
V
A
G
H
L
S
T
S
T
T
V
S
S
S
G
Site 10
T69
A
G
H
L
S
T
S
T
T
V
S
S
S
G
A
Site 11
T70
G
H
L
S
T
S
T
T
V
S
S
S
G
A
Q
Site 12
S72
L
S
T
S
T
T
V
S
S
S
G
A
Q
N
S
Site 13
S79
S
S
S
G
A
Q
N
S
D
S
T
K
K
T
L
Site 14
S81
S
G
A
Q
N
S
D
S
T
K
K
T
L
V
T
Site 15
T85
N
S
D
S
T
K
K
T
L
V
T
L
I
A
N
Site 16
T110
G
G
Q
P
L
I
L
T
Q
N
P
A
P
G
L
Site 17
S141
N
A
N
H
V
T
S
S
P
V
A
S
Q
P
I
Site 18
T210
P
Q
V
F
S
Q
M
T
P
V
R
P
G
S
T
Site 19
S216
M
T
P
V
R
P
G
S
T
M
P
V
R
P
T
Site 20
T223
S
T
M
P
V
R
P
T
T
N
T
F
T
T
V
Site 21
S239
P
A
T
L
T
I
R
S
T
V
P
Q
S
Q
S
Site 22
T240
A
T
L
T
I
R
S
T
V
P
Q
S
Q
S
Q
Site 23
S244
I
R
S
T
V
P
Q
S
Q
S
Q
Q
T
K
S
Site 24
S246
S
T
V
P
Q
S
Q
S
Q
Q
T
K
S
T
P
Site 25
S251
S
Q
S
Q
Q
T
K
S
T
P
S
T
S
T
T
Site 26
T252
Q
S
Q
Q
T
K
S
T
P
S
T
S
T
T
P
Site 27
T255
Q
T
K
S
T
P
S
T
S
T
T
P
T
A
T
Site 28
S256
T
K
S
T
P
S
T
S
T
T
P
T
A
T
Q
Site 29
T258
S
T
P
S
T
S
T
T
P
T
A
T
Q
P
T
Site 30
T260
P
S
T
S
T
T
P
T
A
T
Q
P
T
S
L
Site 31
T262
T
S
T
T
P
T
A
T
Q
P
T
S
L
G
Q
Site 32
S266
P
T
A
T
Q
P
T
S
L
G
Q
L
A
V
Q
Site 33
S274
L
G
Q
L
A
V
Q
S
P
G
Q
S
N
Q
T
Site 34
S278
A
V
Q
S
P
G
Q
S
N
Q
T
T
N
P
K
Site 35
T281
S
P
G
Q
S
N
Q
T
T
N
P
K
L
A
P
Site 36
T282
P
G
Q
S
N
Q
T
T
N
P
K
L
A
P
S
Site 37
S289
T
N
P
K
L
A
P
S
F
P
S
P
P
A
V
Site 38
S292
K
L
A
P
S
F
P
S
P
P
A
V
S
I
A
Site 39
S329
N
T
L
N
T
I
P
S
L
G
Q
S
P
G
P
Site 40
S333
T
I
P
S
L
G
Q
S
P
G
P
V
V
V
S
Site 41
S340
S
P
G
P
V
V
V
S
N
N
S
S
A
H
G
Site 42
S343
P
V
V
V
S
N
N
S
S
A
H
G
S
Q
R
Site 43
S344
V
V
V
S
N
N
S
S
A
H
G
S
Q
R
T
Site 44
S348
N
N
S
S
A
H
G
S
Q
R
T
S
G
P
E
Site 45
T351
S
A
H
G
S
Q
R
T
S
G
P
E
S
S
M
Site 46
S352
A
H
G
S
Q
R
T
S
G
P
E
S
S
M
K
Site 47
S356
Q
R
T
S
G
P
E
S
S
M
K
V
T
S
S
Site 48
S357
R
T
S
G
P
E
S
S
M
K
V
T
S
S
I
Site 49
T361
P
E
S
S
M
K
V
T
S
S
I
P
V
F
D
Site 50
Y404
C
C
P
E
M
V
E
Y
Q
K
K
G
K
S
L
Site 51
S410
E
Y
Q
K
K
G
K
S
L
D
S
E
P
S
V
Site 52
S413
K
K
G
K
S
L
D
S
E
P
S
V
P
S
A
Site 53
S416
K
S
L
D
S
E
P
S
V
P
S
A
A
K
P
Site 54
S419
D
S
E
P
S
V
P
S
A
A
K
P
P
S
P
Site 55
S425
P
S
A
A
K
P
P
S
P
E
K
T
A
P
V
Site 56
T429
K
P
P
S
P
E
K
T
A
P
V
A
S
T
P
Site 57
S434
E
K
T
A
P
V
A
S
T
P
S
S
T
P
I
Site 58
T435
K
T
A
P
V
A
S
T
P
S
S
T
P
I
P
Site 59
S437
A
P
V
A
S
T
P
S
S
T
P
I
P
A
L
Site 60
T439
V
A
S
T
P
S
S
T
P
I
P
A
L
S
P
Site 61
S445
S
T
P
I
P
A
L
S
P
P
T
K
V
P
E
Site 62
T448
I
P
A
L
S
P
P
T
K
V
P
E
P
N
E
Site 63
Y473
I
M
L
V
D
D
F
Y
Y
G
R
D
G
G
K
Site 64
Y474
M
L
V
D
D
F
Y
Y
G
R
D
G
G
K
V
Site 65
T485
G
G
K
V
A
Q
L
T
N
F
P
K
V
A
T
Site 66
T492
T
N
F
P
K
V
A
T
S
F
R
C
P
H
C
Site 67
S493
N
F
P
K
V
A
T
S
F
R
C
P
H
C
T
Site 68
S554
C
H
L
E
N
V
H
S
P
Y
E
S
T
T
K
Site 69
Y556
L
E
N
V
H
S
P
Y
E
S
T
T
K
C
K
Site 70
T582
F
L
Q
H
M
K
D
T
H
K
P
G
E
M
P
Site 71
Y590
H
K
P
G
E
M
P
Y
V
C
Q
V
C
Q
Y
Site 72
S599
C
Q
V
C
Q
Y
R
S
S
L
Y
S
E
V
D
Site 73
S600
Q
V
C
Q
Y
R
S
S
L
Y
S
E
V
D
V
Site 74
Y602
C
Q
Y
R
S
S
L
Y
S
E
V
D
V
H
F
Site 75
S603
Q
Y
R
S
S
L
Y
S
E
V
D
V
H
F
R
Site 76
Y638
G
N
A
F
Q
Q
H
Y
M
R
H
Q
K
R
N
Site 77
Y647
R
H
Q
K
R
N
V
Y
H
C
N
K
C
R
L
Site 78
T672
H
K
L
Q
H
H
K
T
F
R
K
P
K
Q
L
Site 79
T686
L
E
G
L
K
P
G
T
K
V
T
I
R
A
S
Site 80
T689
L
K
P
G
T
K
V
T
I
R
A
S
R
G
Q
Site 81
S693
T
K
V
T
I
R
A
S
R
G
Q
P
R
T
V
Site 82
T699
A
S
R
G
Q
P
R
T
V
P
V
S
S
N
D
Site 83
S703
Q
P
R
T
V
P
V
S
S
N
D
T
P
P
S
Site 84
S704
P
R
T
V
P
V
S
S
N
D
T
P
P
S
A
Site 85
T707
V
P
V
S
S
N
D
T
P
P
S
A
L
Q
E
Site 86
S710
S
S
N
D
T
P
P
S
A
L
Q
E
A
A
P
Site 87
T719
L
Q
E
A
A
P
L
T
S
S
M
D
P
L
P
Site 88
S746
K
R
A
V
R
K
M
S
V
M
G
R
Q
T
C
Site 89
S757
R
Q
T
C
L
E
C
S
F
E
I
P
D
F
P
Site 90
T780
C
S
L
C
R
Y
S
T
C
C
S
R
A
Y
A
Site 91
S799
N
N
H
V
P
R
K
S
P
K
Y
L
A
L
F
Site 92
Y802
V
P
R
K
S
P
K
Y
L
A
L
F
K
N
S
Site 93
S839
K
H
L
V
F
N
P
S
H
R
S
S
S
I
L
Site 94
S842
V
F
N
P
S
H
R
S
S
S
I
L
P
R
G
Site 95
S843
F
N
P
S
H
R
S
S
S
I
L
P
R
G
L
Site 96
S844
N
P
S
H
R
S
S
S
I
L
P
R
G
L
T
Site 97
T851
S
I
L
P
R
G
L
T
W
I
A
H
S
R
H
Site 98
Y874
D
R
N
V
K
N
M
Y
P
P
P
S
F
P
T
Site 99
S878
K
N
M
Y
P
P
P
S
F
P
T
N
K
A
A
Site 100
S889
N
K
A
A
T
V
K
S
A
G
A
T
P
A
E
Site 101
T893
T
V
K
S
A
G
A
T
P
A
E
P
E
E
L
Site 102
S913
P
A
L
P
S
P
A
S
T
A
T
P
P
P
T
Site 103
T914
A
L
P
S
P
A
S
T
A
T
P
P
P
T
P
Site 104
T916
P
S
P
A
S
T
A
T
P
P
P
T
P
T
H
Site 105
T920
S
T
A
T
P
P
P
T
P
T
H
P
Q
A
L
Site 106
S949
V
D
D
Q
D
E
G
S
P
V
T
Q
E
P
E
Site 107
T952
Q
D
E
G
S
P
V
T
Q
E
P
E
L
A
S
Site 108
S959
T
Q
E
P
E
L
A
S
G
G
G
G
S
G
G
Site 109
S974
V
G
K
K
E
Q
L
S
V
K
K
L
R
V
V
Site 110
S1013
W
L
R
R
F
Q
A
S
Q
G
E
N
L
E
G
Site 111
Y1022
G
E
N
L
E
G
K
Y
L
S
F
E
A
E
E
Site 112
S1024
N
L
E
G
K
Y
L
S
F
E
A
E
E
K
L
Site 113
T1037
K
L
A
E
W
V
L
T
Q
R
E
Q
Q
L
P
Site 114
Y1069
E
G
G
F
K
I
S
Y
E
W
A
V
R
F
M
Site 115
T1082
F
M
L
R
H
H
L
T
P
H
A
R
R
A
V
Site 116
T1092
A
R
R
A
V
A
H
T
L
P
K
D
V
A
E
Site 117
T1134
E
I
S
L
F
L
D
T
E
V
L
S
S
D
D
Site 118
S1139
L
D
T
E
V
L
S
S
D
D
R
K
E
N
A
Site 119
T1149
R
K
E
N
A
L
Q
T
V
G
T
G
E
P
W
Site 120
T1152
N
A
L
Q
T
V
G
T
G
E
P
W
C
D
V
Site 121
S1189
Q
P
A
N
M
P
D
S
I
L
L
E
A
K
E
Site 122
S1200
E
A
K
E
S
G
Y
S
D
D
E
I
M
E
L
Site 123
S1222
K
H
T
A
C
Q
R
S
K
G
M
L
V
M
D
Site 124
S1236
D
C
H
R
T
H
L
S
E
E
V
L
A
M
L
Site 125
S1259
V
V
P
A
G
C
S
S
K
I
Q
P
L
D
V
Site 126
T1271
L
D
V
C
I
K
R
T
V
K
N
F
L
H
K
Site 127
T1290
Q
A
R
E
M
A
D
T
A
C
D
S
D
V
L
Site 128
S1338
G
P
D
G
N
I
N
S
P
T
R
N
A
D
M
Site 129
T1340
D
G
N
I
N
S
P
T
R
N
A
D
M
Q
E
Site 130
S1352
M
Q
E
E
L
I
A
S
L
E
E
Q
L
K
L
Site 131
S1360
L
E
E
Q
L
K
L
S
G
E
H
S
E
S
S
Site 132
S1364
L
K
L
S
G
E
H
S
E
S
S
T
P
R
P
Site 133
S1366
L
S
G
E
H
S
E
S
S
T
P
R
P
R
S
Site 134
S1367
S
G
E
H
S
E
S
S
T
P
R
P
R
S
S
Site 135
T1368
G
E
H
S
E
S
S
T
P
R
P
R
S
S
P
Site 136
S1373
S
S
T
P
R
P
R
S
S
P
E
E
T
I
E
Site 137
S1374
S
T
P
R
P
R
S
S
P
E
E
T
I
E
P
Site 138
T1378
P
R
S
S
P
E
E
T
I
E
P
E
S
L
H
Site 139
S1383
E
E
T
I
E
P
E
S
L
H
Q
L
F
E
G
Site 140
S1392
H
Q
L
F
E
G
E
S
E
T
E
S
F
Y
G
Site 141
S1396
E
G
E
S
E
T
E
S
F
Y
G
F
E
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation