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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFTUD1
Full Name:
Elongation factor Tu GTP-binding domain-containing protein 1
Alias:
Elongation factor Tu GTP binding domain containing 1; ETUD1; FAM42A; FLJ13119; HsT19294; RIA1; Ribosome assembly 1
Type:
Protein synthesis elongation protein
Mass (Da):
125430
Number AA:
1120
UniProt ID:
Q7Z2Z2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0003746
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
H
V
D
H
G
K
T
T
L
A
D
C
L
I
S
Site 2
S48
S
S
N
G
I
I
S
S
R
L
A
G
K
L
R
Site 3
S59
G
K
L
R
Y
M
D
S
R
E
D
E
Q
I
R
Site 4
T69
D
E
Q
I
R
G
I
T
M
K
S
S
A
I
S
Site 5
S76
T
M
K
S
S
A
I
S
L
H
Y
A
T
G
N
Site 6
S100
S
P
G
H
V
D
F
S
S
E
V
S
T
A
V
Site 7
S101
P
G
H
V
D
F
S
S
E
V
S
T
A
V
R
Site 8
T105
D
F
S
S
E
V
S
T
A
V
R
I
C
D
G
Site 9
T158
L
I
V
E
L
K
F
T
P
Q
E
A
Y
S
H
Site 10
T194
E
E
R
A
E
R
E
T
E
S
Q
V
N
P
N
Site 11
S196
R
A
E
R
E
T
E
S
Q
V
N
P
N
S
E
Site 12
S202
E
S
Q
V
N
P
N
S
E
Q
G
E
Q
V
Y
Site 13
Y209
S
E
Q
G
E
Q
V
Y
D
W
S
T
G
L
E
Site 14
T218
W
S
T
G
L
E
D
T
D
D
S
H
L
Y
F
Site 15
S221
G
L
E
D
T
D
D
S
H
L
Y
F
S
P
E
Site 16
Y224
D
T
D
D
S
H
L
Y
F
S
P
E
Q
G
N
Site 17
S226
D
D
S
H
L
Y
F
S
P
E
Q
G
N
V
V
Site 18
Y252
I
E
H
F
A
R
I
Y
S
Q
K
I
G
I
K
Site 19
S253
E
H
F
A
R
I
Y
S
Q
K
I
G
I
K
K
Site 20
T266
K
K
E
V
L
M
K
T
L
W
G
D
Y
Y
I
Site 21
Y271
M
K
T
L
W
G
D
Y
Y
I
N
M
K
A
K
Site 22
Y272
K
T
L
W
G
D
Y
Y
I
N
M
K
A
K
K
Site 23
Y305
L
E
N
I
W
S
L
Y
D
A
V
L
K
K
D
Site 24
S335
G
A
R
E
A
R
H
S
D
P
K
V
Q
I
N
Site 25
T370
L
P
S
P
L
D
I
T
A
E
R
V
E
R
L
Site 26
S382
E
R
L
M
C
T
G
S
Q
T
F
D
S
F
P
Site 27
T384
L
M
C
T
G
S
Q
T
F
D
S
F
P
P
E
Site 28
S387
T
G
S
Q
T
F
D
S
F
P
P
E
T
Q
A
Site 29
T434
Q
N
K
P
R
P
L
T
Q
E
E
I
A
Q
R
Site 30
T473
Q
D
G
S
A
I
E
T
C
P
K
G
E
E
P
Site 31
T491
E
Q
Q
V
E
S
M
T
P
K
P
V
L
Q
E
Site 32
S504
Q
E
E
N
N
Q
E
S
F
I
A
F
A
R
V
Site 33
S530
F
V
L
G
P
K
Y
S
P
L
E
F
L
R
R
Site 34
S543
R
R
V
P
L
G
F
S
A
P
P
D
G
L
P
Site 35
Y557
P
Q
V
P
H
M
A
Y
C
A
L
E
N
L
Y
Site 36
Y573
L
M
G
R
E
L
E
Y
L
E
E
V
P
P
G
Site 37
T615
I
P
L
N
F
E
A
T
P
I
V
R
V
A
V
Site 38
T695
P
I
I
P
F
R
E
T
I
T
K
P
P
K
V
Site 39
S726
H
Q
M
K
E
D
Q
S
K
I
P
E
G
I
Q
Site 40
T744
D
G
L
I
T
I
T
T
P
N
K
L
A
T
L
Site 41
T750
T
T
P
N
K
L
A
T
L
S
V
R
A
M
P
Site 42
S752
P
N
K
L
A
T
L
S
V
R
A
M
P
L
P
Site 43
S770
T
Q
I
L
E
E
N
S
D
L
I
R
S
M
E
Site 44
S775
E
N
S
D
L
I
R
S
M
E
Q
L
T
S
S
Site 45
S781
R
S
M
E
Q
L
T
S
S
L
N
E
G
E
N
Site 46
S782
S
M
E
Q
L
T
S
S
L
N
E
G
E
N
T
Site 47
T789
S
L
N
E
G
E
N
T
H
M
I
H
Q
K
T
Site 48
T812
G
K
L
E
Q
H
L
T
G
R
R
W
R
N
I
Site 49
S840
P
N
I
L
V
N
K
S
E
D
F
Q
N
S
V
Site 50
S846
K
S
E
D
F
Q
N
S
V
W
T
G
P
A
D
Site 51
S856
T
G
P
A
D
K
A
S
K
E
A
S
R
Y
R
Site 52
S860
D
K
A
S
K
E
A
S
R
Y
R
D
L
G
N
Site 53
Y862
A
S
K
E
A
S
R
Y
R
D
L
G
N
S
I
Site 54
S868
R
Y
R
D
L
G
N
S
I
V
S
G
F
Q
L
Site 55
S879
G
F
Q
L
A
T
L
S
G
P
M
C
E
E
P
Site 56
S900
V
L
E
K
W
D
L
S
K
F
E
E
Q
G
A
Site 57
S908
K
F
E
E
Q
G
A
S
D
L
A
K
E
G
Q
Site 58
T920
E
G
Q
E
E
N
E
T
C
S
G
G
N
E
N
Site 59
S935
Q
E
L
Q
D
G
C
S
E
A
F
E
K
R
T
Site 60
S943
E
A
F
E
K
R
T
S
Q
K
G
E
S
P
L
Site 61
S948
R
T
S
Q
K
G
E
S
P
L
T
D
C
Y
G
Site 62
T951
Q
K
G
E
S
P
L
T
D
C
Y
G
P
F
S
Site 63
Y954
E
S
P
L
T
D
C
Y
G
P
F
S
G
Q
L
Site 64
Y971
T
M
K
E
A
C
R
Y
A
L
Q
V
K
P
Q
Site 65
Y1000
G
D
V
L
G
R
V
Y
A
V
L
S
K
R
E
Site 66
S1004
G
R
V
Y
A
V
L
S
K
R
E
G
R
V
L
Site 67
T1019
Q
E
E
M
K
E
G
T
D
M
F
I
I
K
A
Site 68
T1044
A
D
E
I
R
K
R
T
S
G
L
A
S
P
Q
Site 69
S1045
D
E
I
R
K
R
T
S
G
L
A
S
P
Q
L
Site 70
S1049
K
R
T
S
G
L
A
S
P
Q
L
V
F
S
H
Site 71
T1070
D
P
F
W
V
P
T
T
E
E
E
Y
L
H
F
Site 72
Y1074
V
P
T
T
E
E
E
Y
L
H
F
G
E
K
A
Site 73
S1083
H
F
G
E
K
A
D
S
E
N
Q
A
R
K
Y
Site 74
Y1090
S
E
N
Q
A
R
K
Y
M
N
A
V
R
K
R
Site 75
Y1101
V
R
K
R
K
G
L
Y
V
E
E
K
I
V
E
Site 76
T1115
E
H
A
E
K
Q
R
T
L
S
K
N
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation