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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERMP1
Full Name:
Endoplasmic reticulum metallopeptidase 1
Alias:
Felix-ina
Type:
Mass (Da):
100213
Number AA:
904
UniProt ID:
Q7Z2K6
International Prot ID:
IPI00257903
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005789
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0008233
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
E
P
L
V
D
G
C
S
G
G
G
R
T
R
K
Site 2
T49
G
C
S
G
G
G
R
T
R
K
R
S
P
G
G
Site 3
S53
G
G
R
T
R
K
R
S
P
G
G
S
G
G
A
Site 4
S57
R
K
R
S
P
G
G
S
G
G
A
S
R
G
A
Site 5
S61
P
G
G
S
G
G
A
S
R
G
A
G
T
G
L
Site 6
T66
G
A
S
R
G
A
G
T
G
L
S
E
V
R
A
Site 7
S69
R
G
A
G
T
G
L
S
E
V
R
A
A
L
G
Site 8
Y115
D
A
L
Q
A
R
D
Y
L
E
H
I
T
S
I
Site 9
S121
D
Y
L
E
H
I
T
S
I
G
P
R
T
T
G
Site 10
T126
I
T
S
I
G
P
R
T
T
G
S
P
E
N
E
Site 11
T127
T
S
I
G
P
R
T
T
G
S
P
E
N
E
I
Site 12
S129
I
G
P
R
T
T
G
S
P
E
N
E
I
L
T
Site 13
T136
S
P
E
N
E
I
L
T
V
H
Y
L
L
E
Q
Site 14
S151
I
K
L
I
E
V
Q
S
N
S
L
H
K
I
S
Site 15
S153
L
I
E
V
Q
S
N
S
L
H
K
I
S
V
D
Site 16
T165
S
V
D
V
Q
R
P
T
G
S
F
S
I
D
F
Site 17
S167
D
V
Q
R
P
T
G
S
F
S
I
D
F
L
G
Site 18
S169
Q
R
P
T
G
S
F
S
I
D
F
L
G
G
F
Site 19
T184
T
S
Y
Y
D
N
I
T
N
V
V
V
K
L
E
Site 20
S208
L
A
N
C
H
F
D
S
V
A
N
S
P
G
A
Site 21
S212
H
F
D
S
V
A
N
S
P
G
A
S
D
D
A
Site 22
S216
V
A
N
S
P
G
A
S
D
D
A
V
S
C
S
Site 23
T234
E
V
L
R
V
L
S
T
S
S
E
A
L
H
H
Site 24
Y302
N
P
W
L
V
Q
A
Y
V
S
A
A
K
H
P
Site 25
S326
F
Q
S
G
I
I
P
S
D
T
D
F
R
I
Y
Site 26
T328
S
G
I
I
P
S
D
T
D
F
R
I
Y
R
D
Site 27
Y333
S
D
T
D
F
R
I
Y
R
D
F
G
N
I
P
Site 28
Y357
G
Y
I
Y
H
T
K
Y
D
T
A
D
R
I
L
Site 29
T359
I
Y
H
T
K
Y
D
T
A
D
R
I
L
T
D
Site 30
T365
D
T
A
D
R
I
L
T
D
S
I
Q
R
A
G
Site 31
S367
A
D
R
I
L
T
D
S
I
Q
R
A
G
D
N
Site 32
S392
S
D
M
L
A
A
A
S
K
Y
R
H
G
N
M
Site 33
S418
A
Y
P
S
R
I
G
S
I
I
N
Y
M
V
V
Site 34
Y422
R
I
G
S
I
I
N
Y
M
V
V
M
G
V
V
Site 35
Y431
V
V
M
G
V
V
L
Y
L
G
K
K
F
L
Q
Site 36
Y446
P
K
H
K
T
G
N
Y
K
K
D
F
L
C
G
Site 37
Y514
H
T
L
A
K
R
F
Y
Y
M
N
A
S
A
Q
Site 38
Y515
T
L
A
K
R
F
Y
Y
M
N
A
S
A
Q
Y
Site 39
S613
F
T
P
I
L
G
R
S
G
S
E
I
P
P
D
Site 40
Y643
S
Y
F
I
N
F
I
Y
L
A
K
S
T
K
K
Site 41
S647
N
F
I
Y
L
A
K
S
T
K
K
T
M
L
T
Site 42
S675
S
G
T
F
F
P
Y
S
S
N
P
A
N
P
K
Site 43
S676
G
T
F
F
P
Y
S
S
N
P
A
N
P
K
P
Site 44
T723
Y
T
G
I
S
H
I
T
P
H
I
P
E
I
N
Site 45
S768
Y
L
P
A
P
E
V
S
P
R
N
P
P
H
F
Site 46
S779
P
P
H
F
R
L
I
S
K
E
Q
T
P
W
D
Site 47
T783
R
L
I
S
K
E
Q
T
P
W
D
S
I
K
L
Site 48
T791
P
W
D
S
I
K
L
T
F
E
A
T
G
P
S
Site 49
S801
A
T
G
P
S
H
M
S
F
Y
V
R
A
H
K
Site 50
Y803
G
P
S
H
M
S
F
Y
V
R
A
H
K
G
S
Site 51
S810
Y
V
R
A
H
K
G
S
T
L
S
Q
W
S
L
Site 52
T811
V
R
A
H
K
G
S
T
L
S
Q
W
S
L
G
Site 53
S813
A
H
K
G
S
T
L
S
Q
W
S
L
G
N
G
Site 54
S816
G
S
T
L
S
Q
W
S
L
G
N
G
T
P
V
Site 55
T821
Q
W
S
L
G
N
G
T
P
V
T
S
K
G
G
Site 56
T824
L
G
N
G
T
P
V
T
S
K
G
G
D
Y
F
Site 57
Y830
V
T
S
K
G
G
D
Y
F
V
F
Y
S
H
G
Site 58
Y834
G
G
D
Y
F
V
F
Y
S
H
G
L
Q
A
S
Site 59
Y868
T
V
A
I
A
A
H
Y
L
S
G
E
D
K
R
Site 60
S870
A
I
A
A
H
Y
L
S
G
E
D
K
R
S
P
Site 61
S876
L
S
G
E
D
K
R
S
P
Q
L
D
A
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation