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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OVCH1
Full Name:
Ovochymase-1
Alias:
Type:
Mass (Da):
125066
Number AA:
1134
UniProt ID:
Q7RTY7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
I
R
M
V
N
M
K
S
K
E
P
A
V
G
S
Site 2
S41
S
K
E
P
A
V
G
S
R
F
F
S
R
I
S
Site 3
S45
A
V
G
S
R
F
F
S
R
I
S
S
W
R
N
Site 4
S48
S
R
F
F
S
R
I
S
S
W
R
N
S
T
V
Site 5
S49
R
F
F
S
R
I
S
S
W
R
N
S
T
V
T
Site 6
S53
R
I
S
S
W
R
N
S
T
V
T
G
H
P
W
Site 7
T54
I
S
S
W
R
N
S
T
V
T
G
H
P
W
Q
Site 8
T56
S
W
R
N
S
T
V
T
G
H
P
W
Q
V
S
Site 9
S63
T
G
H
P
W
Q
V
S
L
K
S
D
E
H
H
Site 10
T84
I
Q
E
D
R
V
V
T
A
A
H
C
L
D
S
Site 11
S91
T
A
A
H
C
L
D
S
L
S
E
K
Q
L
K
Site 12
S93
A
H
C
L
D
S
L
S
E
K
Q
L
K
N
I
Site 13
T101
E
K
Q
L
K
N
I
T
V
T
S
G
E
Y
S
Site 14
S104
L
K
N
I
T
V
T
S
G
E
Y
S
L
F
Q
Site 15
Y107
I
T
V
T
S
G
E
Y
S
L
F
Q
K
D
K
Site 16
S108
T
V
T
S
G
E
Y
S
L
F
Q
K
D
K
Q
Site 17
S122
Q
E
Q
N
I
P
V
S
K
I
I
T
H
P
E
Site 18
T126
I
P
V
S
K
I
I
T
H
P
E
Y
N
S
R
Site 19
Y130
K
I
I
T
H
P
E
Y
N
S
R
E
Y
M
S
Site 20
Y135
P
E
Y
N
S
R
E
Y
M
S
P
D
I
A
L
Site 21
S137
Y
N
S
R
E
Y
M
S
P
D
I
A
L
L
Y
Site 22
S163
Q
P
I
C
L
P
D
S
D
D
K
V
E
P
G
Site 23
S182
S
S
G
W
G
K
I
S
K
T
S
E
Y
S
N
Site 24
T184
G
W
G
K
I
S
K
T
S
E
Y
S
N
V
L
Site 25
T206
M
D
D
R
A
C
N
T
V
L
K
S
M
N
L
Site 26
S266
V
A
G
C
A
G
G
S
V
P
V
R
N
N
H
Site 27
S277
R
N
N
H
V
K
A
S
L
G
I
F
S
K
V
Site 28
S306
L
D
R
G
Q
P
L
S
K
V
G
S
R
Y
I
Site 29
S310
Q
P
L
S
K
V
G
S
R
Y
I
T
K
A
L
Site 30
Y312
L
S
K
V
G
S
R
Y
I
T
K
A
L
S
S
Site 31
T314
K
V
G
S
R
Y
I
T
K
A
L
S
S
V
Q
Site 32
S326
S
V
Q
E
V
N
G
S
Q
R
G
K
G
I
L
Site 33
Y345
Q
V
G
C
D
H
D
Y
V
S
L
R
S
S
S
Site 34
S347
G
C
D
H
D
Y
V
S
L
R
S
S
S
G
V
Site 35
S350
H
D
Y
V
S
L
R
S
S
S
G
V
L
F
N
Site 36
S351
D
Y
V
S
L
R
S
S
S
G
V
L
F
N
Q
Site 37
S352
Y
V
S
L
R
S
S
S
G
V
L
F
N
Q
R
Site 38
S360
G
V
L
F
N
Q
R
S
L
M
E
D
D
G
K
Site 39
S394
E
A
M
V
P
F
V
S
D
T
E
D
S
G
S
Site 40
T396
M
V
P
F
V
S
D
T
E
D
S
G
S
G
F
Site 41
S399
F
V
S
D
T
E
D
S
G
S
G
F
E
L
T
Site 42
S401
S
D
T
E
D
S
G
S
G
F
E
L
T
V
T
Site 43
T406
S
G
S
G
F
E
L
T
V
T
A
V
Q
K
S
Site 44
T408
S
G
F
E
L
T
V
T
A
V
Q
K
S
E
A
Site 45
S413
T
V
T
A
V
Q
K
S
E
A
G
S
G
C
G
Site 46
Y436
G
T
N
H
S
A
K
Y
P
D
L
Y
P
S
N
Site 47
Y440
S
A
K
Y
P
D
L
Y
P
S
N
I
R
C
H
Site 48
T461
E
K
H
I
I
K
L
T
F
E
D
F
A
V
K
Site 49
Y512
S
S
N
M
T
V
I
Y
F
K
S
D
G
K
N
Site 50
S515
M
T
V
I
Y
F
K
S
D
G
K
N
R
L
Q
Site 51
T529
Q
G
F
K
A
R
F
T
I
L
P
S
E
S
L
Site 52
S535
F
T
I
L
P
S
E
S
L
N
K
F
E
P
K
Site 53
S551
P
P
Q
N
N
P
V
S
T
V
K
A
I
L
H
Site 54
T552
P
Q
N
N
P
V
S
T
V
K
A
I
L
H
D
Site 55
S567
V
C
G
I
P
P
F
S
P
Q
W
L
S
R
R
Site 56
S572
P
F
S
P
Q
W
L
S
R
R
I
A
G
G
E
Site 57
S625
Q
L
K
N
N
P
L
S
W
T
I
I
A
G
D
Site 58
S640
H
D
R
N
L
K
E
S
T
E
Q
V
R
R
A
Site 59
T658
I
V
H
E
D
F
N
T
L
S
Y
D
S
D
I
Site 60
S660
H
E
D
F
N
T
L
S
Y
D
S
D
I
A
L
Site 61
Y661
E
D
F
N
T
L
S
Y
D
S
D
I
A
L
I
Site 62
Y676
Q
L
S
S
P
L
E
Y
N
S
V
V
R
P
V
Site 63
S688
R
P
V
C
L
P
H
S
A
E
P
L
F
S
S
Site 64
S714
S
A
D
G
G
L
A
S
R
L
Q
Q
I
Q
V
Site 65
Y733
R
E
V
C
E
H
T
Y
Y
S
A
H
P
G
G
Site 66
Y734
E
V
C
E
H
T
Y
Y
S
A
H
P
G
G
I
Site 67
S816
S
K
I
N
G
P
A
S
L
Q
T
N
N
K
C
Site 68
T825
Q
T
N
N
K
C
K
T
L
K
Q
Q
L
P
P
Site 69
T834
K
Q
Q
L
P
P
P
T
P
S
P
D
S
A
S
Site 70
S836
Q
L
P
P
P
T
P
S
P
D
S
A
S
W
P
Site 71
S839
P
P
T
P
S
P
D
S
A
S
W
P
G
C
C
Site 72
S841
T
P
S
P
D
S
A
S
W
P
G
C
C
S
E
Site 73
S847
A
S
W
P
G
C
C
S
E
A
E
L
E
K
P
Site 74
T860
K
P
R
G
F
F
P
T
P
R
Y
L
L
D
Y
Site 75
Y863
G
F
F
P
T
P
R
Y
L
L
D
Y
R
G
R
Site 76
Y867
T
P
R
Y
L
L
D
Y
R
G
R
L
E
C
S
Site 77
S874
Y
R
G
R
L
E
C
S
W
V
L
R
V
S
P
Site 78
Y908
Q
D
S
V
L
I
I
Y
E
E
R
H
S
K
R
Site 79
S913
I
I
Y
E
E
R
H
S
K
R
K
T
A
G
G
Site 80
T917
E
R
H
S
K
R
K
T
A
G
G
L
H
G
R
Site 81
Y927
G
L
H
G
R
R
L
Y
S
M
T
F
M
S
P
Site 82
S928
L
H
G
R
R
L
Y
S
M
T
F
M
S
P
G
Site 83
T930
G
R
R
L
Y
S
M
T
F
M
S
P
G
P
L
Site 84
S965
K
V
L
G
P
K
D
S
K
I
T
R
L
S
Q
Site 85
S971
D
S
K
I
T
R
L
S
Q
S
S
N
R
E
H
Site 86
S973
K
I
T
R
L
S
Q
S
S
N
R
E
H
L
V
Site 87
S974
I
T
R
L
S
Q
S
S
N
R
E
H
L
V
P
Site 88
Y1042
C
H
G
H
L
R
V
Y
E
G
F
G
P
G
K
Site 89
Y1089
H
I
W
E
N
S
V
Y
D
N
V
R
S
V
G
Site 90
S1105
R
K
Q
K
K
F
A
S
N
L
S
Y
S
M
E
Site 91
S1108
K
K
F
A
S
N
L
S
Y
S
M
E
A
E
K
Site 92
S1116
Y
S
M
E
A
E
K
S
R
I
Q
V
P
A
D
Site 93
S1130
D
L
V
P
A
K
G
S
L
S
G
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation