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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STRC
Full Name:
Stereocilin
Alias:
DFNB16; stereocilin
Type:
Mass (Da):
192970
Number AA:
UniProt ID:
Q7RTU9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007605
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
L
A
P
T
G
P
H
S
L
D
P
G
L
S
F
Site 2
S44
S
F
L
K
S
L
L
S
T
L
D
Q
A
P
Q
Site 3
T45
F
L
K
S
L
L
S
T
L
D
Q
A
P
Q
G
Site 4
S53
L
D
Q
A
P
Q
G
S
L
S
R
S
R
F
F
Site 5
S55
Q
A
P
Q
G
S
L
S
R
S
R
F
F
T
F
Site 6
S57
P
Q
G
S
L
S
R
S
R
F
F
T
F
L
A
Site 7
S68
T
F
L
A
N
I
S
S
S
F
E
P
G
R
M
Site 8
S69
F
L
A
N
I
S
S
S
F
E
P
G
R
M
G
Site 9
T99
R
L
H
D
F
L
V
T
L
R
G
S
P
D
W
Site 10
T125
A
L
L
G
Q
E
Q
T
P
R
D
F
L
V
H
Site 11
T155
L
V
P
G
G
P
P
T
P
T
R
P
P
C
T
Site 12
T157
P
G
G
P
P
T
P
T
R
P
P
C
T
R
D
Site 13
T162
T
P
T
R
P
P
C
T
R
D
G
P
S
D
C
Site 14
S167
P
C
T
R
D
G
P
S
D
C
V
L
A
A
D
Site 15
S197
A
L
V
Q
V
Q
P
S
V
D
P
T
N
A
T
Site 16
T201
V
Q
P
S
V
D
P
T
N
A
T
G
L
D
G
Site 17
Y248
R
T
V
G
A
P
L
Y
A
A
F
Q
E
G
L
Site 18
T259
Q
E
G
L
L
R
V
T
H
S
L
Q
D
E
V
Site 19
S261
G
L
L
R
V
T
H
S
L
Q
D
E
V
F
S
Site 20
S268
S
L
Q
D
E
V
F
S
I
L
G
Q
P
E
P
Site 21
T277
L
G
Q
P
E
P
D
T
N
G
Q
C
Q
G
G
Site 22
S332
G
V
P
L
P
R
A
S
Q
P
S
A
H
I
S
Site 23
S335
L
P
R
A
S
Q
P
S
A
H
I
S
P
R
Q
Site 24
S339
S
Q
P
S
A
H
I
S
P
R
Q
R
R
A
I
Site 25
T347
P
R
Q
R
R
A
I
T
V
E
A
L
C
E
N
Site 26
Y362
H
L
G
P
A
P
P
Y
S
I
S
N
F
S
I
Site 27
S363
L
G
P
A
P
P
Y
S
I
S
N
F
S
I
H
Site 28
T380
C
Q
H
T
K
P
A
T
P
Q
P
H
P
S
T
Site 29
S386
A
T
P
Q
P
H
P
S
T
T
A
I
C
Q
T
Site 30
S431
I
C
S
N
L
S
F
S
A
L
S
G
S
N
R
Site 31
S434
N
L
S
F
S
A
L
S
G
S
N
R
R
L
V
Site 32
S436
S
F
S
A
L
S
G
S
N
R
R
L
V
K
R
Site 33
S454
G
L
L
P
P
P
T
S
C
P
E
G
L
P
P
Site 34
S489
E
R
L
C
G
E
A
S
L
Q
A
V
P
P
S
Site 35
S496
S
L
Q
A
V
P
P
S
N
Q
A
W
V
Q
H
Site 36
T509
Q
H
V
C
Q
G
P
T
P
D
V
T
A
S
P
Site 37
T513
Q
G
P
T
P
D
V
T
A
S
P
P
C
H
I
Site 38
S515
P
T
P
D
V
T
A
S
P
P
C
H
I
G
P
Site 39
S561
L
A
G
Q
C
R
I
S
R
G
G
N
D
T
C
Site 40
S609
S
Q
L
P
R
C
Q
S
S
V
P
A
L
A
H
Site 41
S610
Q
L
P
R
C
Q
S
S
V
P
A
L
A
H
P
Site 42
T628
H
Y
L
L
R
L
L
T
F
L
L
G
P
G
A
Site 43
S658
S
S
L
P
D
N
C
S
F
W
D
A
F
R
P
Site 44
S670
F
R
P
E
G
R
R
S
V
L
R
T
I
G
E
Site 45
T674
G
R
R
S
V
L
R
T
I
G
E
Y
L
E
Q
Site 46
Y678
V
L
R
T
I
G
E
Y
L
E
Q
D
E
E
Q
Site 47
T687
E
Q
D
E
E
Q
P
T
P
S
G
F
E
P
T
Site 48
T694
T
P
S
G
F
E
P
T
V
N
P
S
S
G
I
Site 49
S698
F
E
P
T
V
N
P
S
S
G
I
S
K
M
E
Site 50
S699
E
P
T
V
N
P
S
S
G
I
S
K
M
E
L
Site 51
S748
N
L
Q
Q
L
V
L
S
A
E
R
E
A
A
Q
Site 52
S775
G
K
L
Q
V
P
P
S
E
E
Q
A
L
G
R
Site 53
Y791
T
A
L
L
L
Q
R
Y
P
R
L
T
S
Q
L
Site 54
T795
L
Q
R
Y
P
R
L
T
S
Q
L
F
I
D
L
Site 55
S796
Q
R
Y
P
R
L
T
S
Q
L
F
I
D
L
S
Site 56
Y834
V
L
A
A
I
R
D
Y
S
P
G
M
R
P
E
Site 57
S835
L
A
A
I
R
D
Y
S
P
G
M
R
P
E
Q
Site 58
S886
L
E
N
F
L
Q
L
S
P
H
Q
I
Q
A
L
Site 59
S896
Q
I
Q
A
L
E
D
S
W
P
A
A
G
L
G
Site 60
S913
H
A
R
H
V
L
R
S
L
V
N
Q
S
V
Q
Site 61
S943
L
S
P
E
E
L
Q
S
L
V
P
L
S
D
P
Site 62
S948
L
Q
S
L
V
P
L
S
D
P
T
G
P
V
E
Site 63
T951
L
V
P
L
S
D
P
T
G
P
V
E
R
G
L
Site 64
T966
L
E
C
A
A
N
G
T
L
S
P
E
G
R
V
Site 65
S968
C
A
A
N
G
T
L
S
P
E
G
R
V
A
Y
Site 66
Y975
S
P
E
G
R
V
A
Y
E
L
L
G
V
L
R
Site 67
S990
S
S
G
G
A
V
L
S
P
R
E
L
R
V
W
Site 68
S1013
L
R
F
L
Q
E
L
S
E
P
Q
L
R
A
M
Site 69
T1066
L
P
G
L
S
P
Q
T
L
Q
A
I
P
R
R
Site 70
T1112
D
G
V
K
N
M
G
T
T
G
A
G
P
A
V
Site 71
T1129
P
G
Q
P
I
P
T
T
W
P
D
C
L
L
P
Site 72
S1147
L
K
L
L
Q
L
D
S
L
A
L
L
A
N
R
Site 73
Y1157
L
L
A
N
R
R
R
Y
W
E
L
P
W
S
E
Site 74
T1247
A
M
P
E
P
E
W
T
T
V
G
P
E
L
N
Site 75
T1248
M
P
E
P
E
W
T
T
V
G
P
E
L
N
G
Site 76
S1258
P
E
L
N
G
L
D
S
K
L
L
L
D
L
P
Site 77
T1315
Q
N
L
A
P
K
E
T
P
V
S
G
E
V
L
Site 78
S1318
A
P
K
E
T
P
V
S
G
E
V
L
E
T
L
Site 79
S1336
V
G
F
L
G
T
E
S
T
R
Q
I
P
L
Q
Site 80
S1382
L
G
K
P
E
L
W
S
Q
D
E
V
E
Q
A
Site 81
T1413
R
E
A
L
G
P
E
T
L
E
R
L
L
E
K
Site 82
S1423
R
L
L
E
K
Q
Q
S
W
E
Q
S
R
V
G
Site 83
S1427
K
Q
Q
S
W
E
Q
S
R
V
G
Q
L
C
R
Site 84
T1470
N
C
A
D
V
R
G
T
F
P
A
A
W
S
A
Site 85
S1486
Q
I
A
E
M
E
L
S
D
F
E
D
C
L
T
Site 86
T1493
S
D
F
E
D
C
L
T
L
F
A
G
D
P
G
Site 87
S1574
Q
L
R
I
V
V
S
S
F
L
R
Q
S
G
R
Site 88
S1579
V
S
S
F
L
R
Q
S
G
R
H
V
S
H
L
Site 89
S1584
R
Q
S
G
R
H
V
S
H
L
D
F
V
H
L
Site 90
S1610
P
E
E
L
Q
H
I
S
S
W
E
F
S
Q
A
Site 91
S1611
E
E
L
Q
H
I
S
S
W
E
F
S
Q
A
A
Site 92
S1629
G
T
L
H
L
Q
C
S
E
E
Q
L
E
V
L
Site 93
S1725
P
E
Q
M
A
F
L
S
P
E
Q
R
R
A
V
Site 94
S1742
A
Q
H
E
G
K
E
S
P
E
Q
Q
G
R
S
Site 95
T1750
P
E
Q
Q
G
R
S
T
A
W
G
L
Q
D
W
Site 96
S1761
L
Q
D
W
S
R
P
S
W
S
L
V
L
T
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation