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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NLRC3
Full Name:
Protein NLRC3
Alias:
CARD15-like protein;Caterpiller protein 16.2;Nucleotide-binding oligomerization domain protein 3
Type:
Mass (Da):
114658
Number AA:
1065
UniProt ID:
Q7RTR2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
E
A
G
Q
G
H
G
T
G
S
P
A
E
Q
V
Site 2
S20
G
Q
G
H
G
T
G
S
P
A
E
Q
V
K
A
Site 3
S37
D
L
L
A
G
K
G
S
Q
G
S
Q
A
P
Q
Site 4
S40
A
G
K
G
S
Q
G
S
Q
A
P
Q
A
L
D
Site 5
T49
A
P
Q
A
L
D
R
T
P
D
A
P
L
G
P
Site 6
S58
D
A
P
L
G
P
C
S
N
D
S
R
I
Q
R
Site 7
S61
L
G
P
C
S
N
D
S
R
I
Q
R
H
R
K
Site 8
S72
R
H
R
K
A
L
L
S
K
V
G
G
G
P
E
Site 9
T107
Q
L
R
E
H
D
F
T
Q
V
E
A
T
R
G
Site 10
T121
G
G
G
H
P
A
R
T
V
A
L
D
R
L
F
Site 11
S132
D
R
L
F
L
P
L
S
R
V
S
V
P
P
R
Site 12
T184
L
T
F
R
D
L
N
T
H
E
K
L
C
A
D
Site 13
T226
D
G
L
D
E
C
R
T
P
L
D
F
S
N
T
Site 14
T233
T
P
L
D
F
S
N
T
V
A
C
T
D
P
K
Site 15
S262
G
N
L
F
P
E
V
S
I
W
I
T
S
R
P
Site 16
T266
P
E
V
S
I
W
I
T
S
R
P
S
A
S
G
Site 17
S267
E
V
S
I
W
I
T
S
R
P
S
A
S
G
Q
Site 18
S270
I
W
I
T
S
R
P
S
A
S
G
Q
I
P
G
Site 19
S272
I
T
S
R
P
S
A
S
G
Q
I
P
G
G
L
Site 20
T284
G
G
L
V
D
R
M
T
E
I
R
G
F
N
E
Site 21
T347
G
H
L
W
R
S
R
T
G
P
Q
D
A
E
L
Site 22
T359
A
E
L
W
P
P
R
T
L
C
E
L
Y
S
W
Site 23
Y364
P
R
T
L
C
E
L
Y
S
W
Y
F
R
M
A
Site 24
S383
G
Q
E
K
G
K
A
S
P
R
I
E
Q
V
A
Site 25
T399
G
G
R
K
M
V
G
T
L
G
R
L
A
F
H
Site 26
Y413
H
G
L
L
K
K
K
Y
V
F
Y
E
Q
D
M
Site 27
Y416
L
K
K
K
Y
V
F
Y
E
Q
D
M
K
A
F
Site 28
S436
L
L
Q
G
A
P
C
S
C
F
L
Q
R
E
E
Site 29
T444
C
F
L
Q
R
E
E
T
L
A
S
S
V
A
Y
Site 30
S447
Q
R
E
E
T
L
A
S
S
V
A
Y
C
F
T
Site 31
S448
R
E
E
T
L
A
S
S
V
A
Y
C
F
T
H
Site 32
Y467
E
F
V
A
A
A
Y
Y
Y
G
A
S
R
R
A
Site 33
S471
A
A
Y
Y
Y
G
A
S
R
R
A
I
F
D
L
Site 34
T493
W
P
R
L
G
F
L
T
H
F
R
S
A
A
Q
Site 35
S497
G
F
L
T
H
F
R
S
A
A
Q
R
A
M
Q
Site 36
Y542
A
Q
G
E
H
Q
A
Y
R
T
Q
V
A
E
L
Site 37
T577
C
L
H
E
L
Q
H
T
E
L
A
R
S
V
E
Site 38
S582
Q
H
T
E
L
A
R
S
V
E
E
A
M
E
S
Site 39
S589
S
V
E
E
A
M
E
S
G
A
L
A
R
L
T
Site 40
T596
S
G
A
L
A
R
L
T
G
P
A
H
R
A
A
Site 41
S623
Q
E
A
N
L
S
L
S
L
S
Q
G
V
L
Q
Site 42
T646
C
R
K
L
R
L
D
T
N
Q
F
Q
D
P
V
Site 43
S662
E
L
L
G
S
V
L
S
G
K
D
C
R
I
Q
Site 44
S672
D
C
R
I
Q
K
I
S
L
A
E
N
Q
I
S
Site 45
S679
S
L
A
E
N
Q
I
S
N
K
G
A
K
A
L
Site 46
S695
R
S
L
L
V
N
R
S
L
T
S
L
D
L
R
Site 47
T697
L
L
V
N
R
S
L
T
S
L
D
L
R
G
N
Site 48
S698
L
V
N
R
S
L
T
S
L
D
L
R
G
N
S
Site 49
S705
S
L
D
L
R
G
N
S
I
G
P
Q
G
A
K
Site 50
T723
D
A
L
K
I
N
R
T
L
T
S
L
S
L
Q
Site 51
T725
L
K
I
N
R
T
L
T
S
L
S
L
Q
G
N
Site 52
S726
K
I
N
R
T
L
T
S
L
S
L
Q
G
N
T
Site 53
S728
N
R
T
L
T
S
L
S
L
Q
G
N
T
V
R
Site 54
T733
S
L
S
L
Q
G
N
T
V
R
D
D
G
A
R
Site 55
S741
V
R
D
D
G
A
R
S
M
A
E
A
L
A
S
Site 56
T751
E
A
L
A
S
N
R
T
L
S
M
L
H
L
Q
Site 57
S753
L
A
S
N
R
T
L
S
M
L
H
L
Q
K
N
Site 58
S761
M
L
H
L
Q
K
N
S
I
G
P
M
G
A
Q
Site 59
S779
D
A
L
K
Q
N
R
S
L
K
E
L
M
F
S
Site 60
S786
S
L
K
E
L
M
F
S
S
N
S
I
G
D
G
Site 61
S787
L
K
E
L
M
F
S
S
N
S
I
G
D
G
G
Site 62
S789
E
L
M
F
S
S
N
S
I
G
D
G
G
A
K
Site 63
S810
K
V
N
Q
G
L
E
S
L
D
L
Q
S
N
S
Site 64
S815
L
E
S
L
D
L
Q
S
N
S
I
S
D
A
G
Site 65
S817
S
L
D
L
Q
S
N
S
I
S
D
A
G
V
A
Site 66
S838
C
T
N
Q
T
L
L
S
L
S
L
R
E
N
S
Site 67
S840
N
Q
T
L
L
S
L
S
L
R
E
N
S
I
S
Site 68
S845
S
L
S
L
R
E
N
S
I
S
P
E
G
A
Q
Site 69
S847
S
L
R
E
N
S
I
S
P
E
G
A
Q
A
I
Site 70
T870
T
L
K
N
L
D
L
T
A
N
L
L
H
D
Q
Site 71
T893
V
R
E
N
R
T
L
T
S
L
H
L
Q
W
N
Site 72
S919
Q
A
L
Q
L
N
R
S
L
T
S
L
D
L
Q
Site 73
T921
L
Q
L
N
R
S
L
T
S
L
D
L
Q
E
N
Site 74
S1002
A
N
A
L
K
V
N
S
S
L
R
R
L
N
L
Site 75
S1003
N
A
L
K
V
N
S
S
L
R
R
L
N
L
Q
Site 76
S1045
Q
G
N
H
I
G
D
S
G
A
R
M
I
S
E
Site 77
S1051
D
S
G
A
R
M
I
S
E
A
I
K
T
N
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation