KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
MICAL3
Full Name:
Protein MICAL-3
Alias:
K1364; KIAA0819; KIAA1364; MICAL-3; MICAL3 protein; Microtubule associated monoxygenase, calponin and LIM domain containing 3
Type:
Mass (Da):
109911
Number AA:
976
UniProt ID:
Q7RTP6
International Prot ID:
IPI00177937
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0004497
GO:0008270
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
F
D
R
F
V
Q
A
T
T
C
K
G
T
L
K
Site 2
Y46
L
E
L
K
P
K
D
Y
R
S
F
Y
H
K
L
Site 3
Y50
P
K
D
Y
R
S
F
Y
H
K
L
K
S
K
L
Site 4
Y59
K
L
K
S
K
L
N
Y
W
K
A
K
A
L
W
Site 5
T73
I
A
K
R
L
R
G
T
P
E
R
I
E
L
E
Site 6
S74
A
K
L
D
K
R
G
S
H
K
D
Y
K
K
G
Site 7
Y78
K
R
G
S
H
K
D
Y
K
K
G
K
A
C
T
Site 8
S142
E
E
P
R
L
P
P
S
D
L
G
G
V
P
W
Site 9
S163
H
A
L
L
K
G
K
S
E
E
E
L
E
A
S
Site 10
T208
R
A
L
V
H
P
K
T
H
P
V
S
E
Y
E
Site 11
S212
H
P
K
T
H
P
V
S
E
Y
E
F
E
V
I
Site 12
Y214
K
T
H
P
V
S
E
Y
E
F
E
V
I
I
G
Site 13
T228
G
G
D
G
R
R
N
T
L
E
G
F
R
R
K
Site 14
T254
A
N
F
I
N
R
N
T
T
A
E
A
K
V
E
Site 15
T255
N
F
I
N
R
N
T
T
A
E
A
K
V
E
E
Site 16
S274
A
E
L
E
L
R
V
S
E
D
E
E
K
L
P
Site 17
T282
F
Q
E
L
R
E
A
T
G
I
D
L
E
N
I
Site 18
Y291
I
D
L
E
N
I
V
Y
Y
K
D
D
T
H
Y
Site 19
Y292
D
L
E
N
I
V
Y
Y
K
D
D
T
H
Y
F
Site 20
T295
E
R
G
P
S
Q
A
T
S
P
I
R
S
P
Q
Site 21
S296
R
G
P
S
Q
A
T
S
P
I
R
S
P
Q
E
Site 22
Y298
Y
Y
K
D
D
T
H
Y
F
V
M
T
A
K
K
Site 23
S326
A
D
T
E
L
L
L
S
R
E
N
V
D
Q
E
Site 24
S332
P
A
A
T
Q
E
K
S
P
E
E
R
L
F
P
Site 25
S337
V
D
Q
E
A
L
L
S
Y
A
R
E
A
A
D
Site 26
T347
R
E
A
A
D
F
S
T
Q
Q
Q
L
P
S
L
Site 27
S353
S
T
Q
Q
Q
L
P
S
L
D
F
A
I
N
H
Site 28
S361
S
D
L
K
A
V
H
S
P
I
R
S
Q
P
V
Site 29
Y361
L
D
F
A
I
N
H
Y
G
Q
P
D
V
A
M
Site 30
S418
T
V
P
S
P
T
Q
S
P
I
R
F
Q
P
A
Site 31
S427
D
S
A
W
M
V
R
S
W
S
L
G
T
S
P
Site 32
S429
A
W
M
V
R
S
W
S
L
G
T
S
P
L
E
Site 33
T429
F
Q
P
A
P
A
K
T
S
T
P
L
A
P
L
Site 34
T431
P
A
P
A
K
T
S
T
P
L
A
P
L
P
V
Site 35
S433
R
S
W
S
L
G
T
S
P
L
E
V
L
A
E
Site 36
S440
L
A
P
L
P
V
Q
S
Q
S
D
T
K
D
R
Site 37
S443
E
V
L
A
E
R
E
S
I
Y
R
L
L
P
Q
Site 38
T444
P
V
Q
S
Q
S
D
T
K
D
R
L
G
S
P
Site 39
S450
D
T
K
D
R
L
G
S
P
L
A
V
D
E
A
Site 40
T451
I
Y
R
L
L
P
Q
T
T
P
E
N
V
S
K
Site 41
T452
Y
R
L
L
P
Q
T
T
P
E
N
V
S
K
N
Site 42
S457
Q
T
T
P
E
N
V
S
K
N
F
S
Q
Y
S
Site 43
S461
E
N
V
S
K
N
F
S
Q
Y
S
I
D
P
V
Site 44
S464
S
K
N
F
S
Q
Y
S
I
D
P
V
T
R
Y
Site 45
T469
Q
Y
S
I
D
P
V
T
R
Y
P
N
I
N
V
Site 46
Y471
S
I
D
P
V
T
R
Y
P
N
I
N
V
N
F
Site 47
S477
K
S
A
E
I
R
R
S
L
G
L
T
P
V
D
Site 48
T481
I
R
R
S
L
G
L
T
P
V
D
R
S
K
G
Site 49
S482
N
V
N
F
L
R
P
S
Q
V
R
H
L
Y
D
Site 50
Y488
P
S
Q
V
R
H
L
Y
D
T
G
E
T
K
D
Site 51
T490
Q
V
R
H
L
Y
D
T
G
E
T
K
D
I
H
Site 52
S506
E
M
E
S
L
V
N
S
R
T
T
P
K
L
T
Site 53
S507
P
V
S
L
K
S
Y
S
V
E
K
S
P
Q
D
Site 54
T508
E
S
L
V
N
S
R
T
T
P
K
L
T
R
N
Site 55
T509
S
L
V
N
S
R
T
T
P
K
L
T
R
N
E
Site 56
S511
K
S
Y
S
V
E
K
S
P
Q
D
E
G
L
H
Site 57
T513
S
R
T
T
P
K
L
T
R
N
E
S
V
A
R
Site 58
S517
P
K
L
T
R
N
E
S
V
A
R
S
S
K
L
Site 59
S521
R
N
E
S
V
A
R
S
S
K
L
L
G
W
C
Site 60
S522
N
E
S
V
A
R
S
S
K
L
L
G
W
C
Q
Site 61
S524
L
H
L
L
K
P
L
S
I
P
K
R
L
G
L
Site 62
Y535
C
Q
R
Q
T
D
G
Y
A
G
V
N
V
T
D
Site 63
S569
P
D
L
I
D
F
D
S
L
D
E
Q
N
V
E
Site 64
S593
A
E
K
E
L
G
I
S
P
I
M
T
G
K
E
Site 65
T597
L
G
I
S
P
I
M
T
G
K
E
M
A
S
V
Site 66
S603
M
T
G
K
E
M
A
S
V
G
E
P
D
K
L
Site 67
S611
V
G
E
P
D
K
L
S
M
V
M
Y
L
T
Q
Site 68
S626
F
Y
E
M
F
K
D
S
L
P
S
S
D
T
L
Site 69
S630
F
K
D
S
L
P
S
S
D
T
L
D
L
N
A
Site 70
T632
D
S
L
P
S
S
D
T
L
D
L
N
A
E
E
Site 71
S646
E
K
A
V
L
I
A
S
T
R
S
P
I
S
F
Site 72
S649
V
L
I
A
S
T
R
S
P
I
S
F
L
S
K
Site 73
S652
A
S
T
R
S
P
I
S
F
L
S
K
L
G
Q
Site 74
S655
R
S
P
I
S
F
L
S
K
L
G
Q
T
I
S
Site 75
S662
S
K
L
G
Q
T
I
S
R
K
R
S
P
K
D
Site 76
S666
Q
T
I
S
R
K
R
S
P
K
D
K
K
E
K
Site 77
T684
G
A
G
K
R
R
K
T
S
Q
S
E
E
E
E
Site 78
S685
A
G
K
R
R
K
T
S
Q
S
E
E
E
E
A
Site 79
S687
K
R
R
K
T
S
Q
S
E
E
E
E
A
P
R
Site 80
T702
G
H
R
G
E
R
P
T
L
V
S
T
L
T
D
Site 81
S705
G
E
R
P
T
L
V
S
T
L
T
D
R
R
M
Site 82
T706
E
R
P
T
L
V
S
T
L
T
D
R
R
M
D
Site 83
T708
P
T
L
V
S
T
L
T
D
R
R
M
D
V
A
Site 84
Y724
G
N
Q
N
K
V
K
Y
M
A
T
Q
L
L
A
Site 85
T727
N
K
V
K
Y
M
A
T
Q
L
L
A
K
F
E
Site 86
T749
I
G
I
R
R
Q
L
T
Q
E
R
G
A
S
Q
Site 87
S755
L
T
Q
E
R
G
A
S
Q
P
S
C
C
L
P
Site 88
T770
G
Q
V
R
P
A
P
T
P
R
W
K
Q
G
S
Site 89
S780
R
K
A
S
S
A
P
S
Q
G
K
E
R
R
P
Site 90
Y793
L
G
G
S
D
T
C
Y
F
C
Q
K
R
V
Y
Site 91
Y800
Y
F
C
Q
K
R
V
Y
V
M
E
R
L
S
A
Site 92
S806
V
Y
V
M
E
R
L
S
A
E
G
K
F
F
H
Site 93
Y821
R
S
C
F
K
C
E
Y
C
A
T
T
L
R
L
Site 94
T825
K
C
E
Y
C
A
T
T
L
R
L
S
A
Y
A
Site 95
Y831
T
T
L
R
L
S
A
Y
A
Y
D
I
E
D
G
Site 96
Y833
L
R
L
S
A
Y
A
Y
D
I
E
D
G
K
F
Site 97
Y841
D
I
E
D
G
K
F
Y
C
K
P
H
Y
C
Y
Site 98
Y846
K
F
Y
C
K
P
H
Y
C
Y
R
L
S
G
Y
Site 99
T878
G
P
L
Q
D
G
A
T
T
D
A
N
G
R
A
Site 100
S891
R
A
N
A
V
A
S
S
T
E
R
T
P
G
S
Site 101
T892
A
N
A
V
A
S
S
T
E
R
T
P
G
S
G
Site 102
T895
V
A
S
S
T
E
R
T
P
G
S
G
V
N
G
Site 103
S898
S
T
E
R
T
P
G
S
G
V
N
G
L
E
E
Site 104
T903
D
D
K
S
C
P
S
T
P
S
S
G
A
T
V
Site 105
S907
V
N
G
L
E
E
P
S
I
A
K
R
L
R
G
Site 106
T915
I
A
K
R
L
R
G
T
P
E
R
I
E
L
E
Site 107
Y924
E
R
I
E
L
E
N
Y
R
L
S
L
R
Q
A
Site 108
S927
E
L
E
N
Y
R
L
S
L
R
Q
A
E
A
L
Site 109
S932
L
Q
L
R
R
Q
L
S
F
S
E
D
S
D
L
Site 110
S934
L
R
R
Q
L
S
F
S
E
D
S
D
L
S
S
Site 111
S937
Q
L
S
F
S
E
D
S
D
L
S
S
D
D
V
Site 112
S940
F
S
E
D
S
D
L
S
S
D
D
V
L
E
K
Site 113
S941
S
E
D
S
D
L
S
S
D
D
V
L
E
K
S
Site 114
T953
N
L
S
S
V
L
D
T
G
A
E
E
D
V
A
Site 115
S961
G
A
E
E
D
V
A
S
R
S
A
R
R
A
A
Site 116
S963
E
E
D
V
A
S
R
S
A
R
R
A
A
G
R
Site 117
S1142
K
G
F
S
L
N
W
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation