KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
EEPD1
Full Name:
Endonuclease/exonuclease/phosphatase family domain-containing protein 1
Alias:
Endonuclease/exonuclease/phosphatase family domain containing 1; Kiaa1706
Type:
Mass (Da):
62430
Number AA:
569
UniProt ID:
Q7L9B9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
S
T
L
G
C
H
R
S
I
P
R
D
P
S
D
Site 2
S16
R
S
I
P
R
D
P
S
D
L
S
H
S
R
K
Site 3
S19
P
R
D
P
S
D
L
S
H
S
R
K
F
S
A
Site 4
S21
D
P
S
D
L
S
H
S
R
K
F
S
A
A
C
Site 5
S25
L
S
H
S
R
K
F
S
A
A
C
N
F
S
N
Site 6
S31
F
S
A
A
C
N
F
S
N
I
L
V
N
Q
E
Site 7
T52
A
T
E
E
E
L
M
T
L
P
G
V
T
R
A
Site 8
S63
V
T
R
A
V
A
R
S
I
V
E
Y
R
E
Y
Site 9
Y70
S
I
V
E
Y
R
E
Y
I
G
G
F
K
K
V
Site 10
S101
V
K
F
E
I
C
V
S
S
K
G
S
S
A
Q
Site 11
S102
K
F
E
I
C
V
S
S
K
G
S
S
A
Q
H
Site 12
S105
I
C
V
S
S
K
G
S
S
A
Q
H
S
P
S
Site 13
S106
C
V
S
S
K
G
S
S
A
Q
H
S
P
S
S
Site 14
S110
K
G
S
S
A
Q
H
S
P
S
S
L
R
R
D
Site 15
S112
S
S
A
Q
H
S
P
S
S
L
R
R
D
L
L
Site 16
S113
S
A
Q
H
S
P
S
S
L
R
R
D
L
L
A
Site 17
T129
Q
Q
P
H
H
L
A
T
A
V
P
L
T
P
R
Site 18
T134
L
A
T
A
V
P
L
T
P
R
V
N
I
N
T
Site 19
T141
T
P
R
V
N
I
N
T
A
T
P
A
Q
L
M
Site 20
S149
A
T
P
A
Q
L
M
S
V
R
G
L
S
E
K
Site 21
S160
L
S
E
K
M
A
L
S
I
V
D
F
R
R
E
Site 22
S173
R
E
H
G
P
F
R
S
V
E
D
L
V
R
M
Site 23
S200
H
Q
V
F
A
E
R
S
R
P
P
S
T
H
T
Site 24
S204
A
E
R
S
R
P
P
S
T
H
T
N
G
G
L
Site 25
T205
E
R
S
R
P
P
S
T
H
T
N
G
G
L
T
Site 26
T212
T
H
T
N
G
G
L
T
F
T
A
K
P
H
P
Site 27
T214
T
N
G
G
L
T
F
T
A
K
P
H
P
S
P
Site 28
S220
F
T
A
K
P
H
P
S
P
T
S
L
S
L
Q
Site 29
S223
K
P
H
P
S
P
T
S
L
S
L
Q
S
E
D
Site 30
S225
H
P
S
P
T
S
L
S
L
Q
S
E
D
L
D
Site 31
S243
G
G
P
T
Q
I
I
S
T
R
P
S
V
E
A
Site 32
S247
Q
I
I
S
T
R
P
S
V
E
A
F
G
G
T
Site 33
T265
R
P
V
L
R
L
A
T
W
N
L
Q
G
C
S
Site 34
T313
E
A
L
E
K
F
C
T
E
L
N
Q
P
T
L
Site 35
S369
M
E
L
R
D
A
G
S
Q
E
S
S
P
S
N
Site 36
S372
R
D
A
G
S
Q
E
S
S
P
S
N
G
H
G
Site 37
S373
D
A
G
S
Q
E
S
S
P
S
N
G
H
G
K
Site 38
S375
G
S
Q
E
S
S
P
S
N
G
H
G
K
L
A
Site 39
S385
H
G
K
L
A
G
P
S
P
Y
L
G
R
F
K
Site 40
Y387
K
L
A
G
P
S
P
Y
L
G
R
F
K
V
G
Site 41
S413
A
A
L
T
L
L
G
S
E
N
P
S
K
N
H
Site 42
S417
L
L
G
S
E
N
P
S
K
N
H
S
D
G
H
Site 43
S421
E
N
P
S
K
N
H
S
D
G
H
R
L
A
S
Site 44
S428
S
D
G
H
R
L
A
S
F
A
Q
T
L
Q
E
Site 45
T432
R
L
A
S
F
A
Q
T
L
Q
E
T
L
K
G
Site 46
S455
D
F
G
Q
G
P
D
S
N
D
Y
D
I
L
R
Site 47
Y458
Q
G
P
D
S
N
D
Y
D
I
L
R
K
E
K
Site 48
T474
H
H
L
I
P
A
H
T
F
T
N
I
S
T
K
Site 49
T480
H
T
F
T
N
I
S
T
K
N
P
Q
G
S
K
Site 50
S488
K
N
P
Q
G
S
K
S
L
D
N
I
W
I
S
Site 51
S495
S
L
D
N
I
W
I
S
K
S
L
K
K
V
F
Site 52
S497
D
N
I
W
I
S
K
S
L
K
K
V
F
T
G
Site 53
T540
P
V
L
A
E
F
Y
T
E
K
D
W
S
K
K
Site 54
S554
K
D
A
P
R
N
G
S
G
V
A
L
E
R
S
Site 55
S561
S
G
V
A
L
E
R
S
E
A
N
I
K
H
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation