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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DET1
Full Name:
DET1 homolog
Alias:
De-etiolated-1 homolog
Type:
Mass (Da):
63848
Number AA:
550
UniProt ID:
Q7L5Y6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
R
L
E
R
R
R
I
S
S
G
K
A
G
T
H
Site 2
S29
L
E
R
R
R
I
S
S
G
K
A
G
T
H
W
Site 3
S66
P
C
F
L
R
K
F
S
P
D
G
R
Y
F
I
Site 4
Y71
K
F
S
P
D
G
R
Y
F
I
A
F
S
S
D
Site 5
S77
R
Y
F
I
A
F
S
S
D
Q
T
S
L
E
I
Site 6
T80
I
A
F
S
S
D
Q
T
S
L
E
I
Y
E
Y
Site 7
S81
A
F
S
S
D
Q
T
S
L
E
I
Y
E
Y
Q
Site 8
Y85
D
Q
T
S
L
E
I
Y
E
Y
Q
G
C
Q
A
Site 9
Y87
T
S
L
E
I
Y
E
Y
Q
G
C
Q
A
A
E
Site 10
Y100
A
E
D
L
L
Q
G
Y
E
G
E
I
L
S
N
Site 11
S106
G
Y
E
G
E
I
L
S
N
G
N
D
Q
R
S
Site 12
S113
S
N
G
N
D
Q
R
S
V
N
I
R
G
R
L
Site 13
S145
E
H
L
N
R
E
C
S
L
F
T
D
D
C
R
Site 14
Y174
H
P
P
F
F
E
V
Y
R
N
S
E
S
V
T
Site 15
S177
F
F
E
V
Y
R
N
S
E
S
V
T
P
N
P
Site 16
S179
E
V
Y
R
N
S
E
S
V
T
P
N
P
R
S
Site 17
T181
Y
R
N
S
E
S
V
T
P
N
P
R
S
P
L
Site 18
S186
S
V
T
P
N
P
R
S
P
L
E
D
Y
S
L
Site 19
Y191
P
R
S
P
L
E
D
Y
S
L
H
I
I
D
L
Site 20
S192
R
S
P
L
E
D
Y
S
L
H
I
I
D
L
H
Site 21
T200
L
H
I
I
D
L
H
T
G
R
L
C
D
T
R
Site 22
T208
G
R
L
C
D
T
R
T
F
K
C
D
K
V
V
Site 23
S217
K
C
D
K
V
V
L
S
H
N
Q
G
L
Y
L
Site 24
Y223
L
S
H
N
Q
G
L
Y
L
Y
K
N
I
L
A
Site 25
Y261
R
T
I
G
R
F
C
Y
E
D
D
L
L
T
V
Site 26
S279
F
P
E
V
Q
R
D
S
Q
T
G
M
A
N
P
Site 27
T281
E
V
Q
R
D
S
Q
T
G
M
A
N
P
F
R
Site 28
S294
F
R
D
P
F
I
N
S
L
K
H
R
L
L
V
Site 29
Y302
L
K
H
R
L
L
V
Y
L
W
R
R
A
E
Q
Site 30
S312
R
R
A
E
Q
D
G
S
A
M
A
K
R
R
F
Site 31
Y322
A
K
R
R
F
F
Q
Y
F
D
Q
L
R
Q
L
Site 32
T353
Y
T
S
E
D
V
V
T
L
R
V
T
D
P
S
Site 33
T357
D
V
V
T
L
R
V
T
D
P
S
Q
A
S
F
Site 34
T401
C
D
L
F
R
N
A
T
L
H
S
E
V
Q
F
Site 35
S404
F
R
N
A
T
L
H
S
E
V
Q
F
P
C
S
Site 36
S411
S
E
V
Q
F
P
C
S
A
S
S
N
N
F
A
Site 37
T428
I
Q
R
R
F
K
D
T
I
I
N
A
K
Y
G
Site 38
Y434
D
T
I
I
N
A
K
Y
G
G
H
T
E
A
V
Site 39
S454
Q
L
P
I
S
A
Q
S
Y
S
G
S
P
Y
L
Site 40
S456
P
I
S
A
Q
S
Y
S
G
S
P
Y
L
D
L
Site 41
S458
S
A
Q
S
Y
S
G
S
P
Y
L
D
L
S
L
Site 42
Y460
Q
S
Y
S
G
S
P
Y
L
D
L
S
L
F
S
Site 43
S464
G
S
P
Y
L
D
L
S
L
F
S
Y
D
D
K
Site 44
S467
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Site 45
S474
S
Y
D
D
K
W
V
S
V
M
E
R
P
K
T
Site 46
T481
S
V
M
E
R
P
K
T
C
G
D
H
P
I
R
Site 47
Y490
G
D
H
P
I
R
F
Y
A
R
D
S
G
L
L
Site 48
S531
P
F
E
P
F
A
I
S
V
Q
R
T
N
A
E
Site 49
Y539
V
Q
R
T
N
A
E
Y
V
V
N
F
H
M
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation