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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM194A
Full Name:
Protein FAM194A
Alias:
Type:
Mass (Da):
75255
Number AA:
663
UniProt ID:
Q7L0X2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
H
L
R
S
P
S
G
F
G
D
P
Site 2
S8
M
A
H
L
R
S
P
S
G
F
G
D
P
G
K
Site 3
T72
Q
E
L
E
A
P
E
T
F
S
E
E
Y
L
W
Site 4
Y87
K
V
T
D
I
G
D
Y
D
D
D
F
P
D
V
Site 5
S113
L
T
S
T
F
V
P
S
Q
S
A
T
S
T
E
Site 6
S115
S
T
F
V
P
S
Q
S
A
T
S
T
E
T
P
Site 7
T117
F
V
P
S
Q
S
A
T
S
T
E
T
P
S
A
Site 8
T119
P
S
Q
S
A
T
S
T
E
T
P
S
A
S
P
Site 9
T121
Q
S
A
T
S
T
E
T
P
S
A
S
P
P
S
Site 10
S123
A
T
S
T
E
T
P
S
A
S
P
P
S
S
T
Site 11
S125
S
T
E
T
P
S
A
S
P
P
S
S
T
S
S
Site 12
S128
T
P
S
A
S
P
P
S
S
T
S
S
H
K
S
Site 13
S129
P
S
A
S
P
P
S
S
T
S
S
H
K
S
F
Site 14
T130
S
A
S
P
P
S
S
T
S
S
H
K
S
F
P
Site 15
S131
A
S
P
P
S
S
T
S
S
H
K
S
F
P
K
Site 16
S132
S
P
P
S
S
T
S
S
H
K
S
F
P
K
I
Site 17
S135
S
S
T
S
S
H
K
S
F
P
K
I
F
Q
T
Site 18
T142
S
F
P
K
I
F
Q
T
F
R
K
D
M
S
E
Site 19
S151
R
K
D
M
S
E
M
S
I
D
R
N
I
H
R
Site 20
S161
R
N
I
H
R
N
L
S
P
G
I
P
V
S
V
Site 21
S167
L
S
P
G
I
P
V
S
V
Q
T
E
E
S
W
Site 22
S173
V
S
V
Q
T
E
E
S
W
L
Q
D
L
S
D
Site 23
S179
E
S
W
L
Q
D
L
S
D
K
V
Q
S
R
K
Site 24
S200
A
E
P
E
C
L
A
S
K
L
R
E
K
W
V
Site 25
Y219
E
S
K
L
N
I
L
Y
E
L
E
F
K
E
D
Site 26
T229
E
F
K
E
D
F
I
T
L
F
E
P
S
L
R
Site 27
S245
L
P
S
I
G
P
P
S
I
L
A
Y
K
E
E
Site 28
Y249
G
P
P
S
I
L
A
Y
K
E
E
S
S
N
L
Site 29
T267
F
K
D
E
E
E
E
T
S
P
K
C
E
F
C
Site 30
S268
K
D
E
E
E
E
T
S
P
K
C
E
F
C
G
Site 31
S276
P
K
C
E
F
C
G
S
D
L
R
A
F
F
S
Site 32
S283
S
D
L
R
A
F
F
S
N
V
D
V
S
S
E
Site 33
S288
F
F
S
N
V
D
V
S
S
E
P
K
G
H
A
Site 34
S289
F
S
N
V
D
V
S
S
E
P
K
G
H
A
S
Site 35
Y307
A
F
Q
N
L
I
D
Y
I
Y
E
E
Q
I
K
Site 36
Y309
Q
N
L
I
D
Y
I
Y
E
E
Q
I
K
T
K
Site 37
T315
I
Y
E
E
Q
I
K
T
K
P
P
K
A
E
L
Site 38
T365
A
I
I
S
R
E
Q
T
H
F
S
E
D
D
S
Site 39
S368
S
R
E
Q
T
H
F
S
E
D
D
S
K
R
L
Site 40
S372
T
H
F
S
E
D
D
S
K
R
L
K
T
I
S
Site 41
T377
D
D
S
K
R
L
K
T
I
S
Y
Q
L
S
V
Site 42
S379
S
K
R
L
K
T
I
S
Y
Q
L
S
V
D
I
Site 43
S383
K
T
I
S
Y
Q
L
S
V
D
I
P
E
K
Q
Site 44
Y430
N
E
L
L
E
K
H
Y
K
H
G
S
K
F
L
Site 45
S434
E
K
H
Y
K
H
G
S
K
F
L
T
S
F
P
Site 46
T438
K
H
G
S
K
F
L
T
S
F
P
D
G
T
T
Site 47
S439
H
G
S
K
F
L
T
S
F
P
D
G
T
T
Q
Site 48
T444
L
T
S
F
P
D
G
T
T
Q
I
F
Y
P
S
Site 49
T445
T
S
F
P
D
G
T
T
Q
I
F
Y
P
S
G
Site 50
Y449
D
G
T
T
Q
I
F
Y
P
S
G
N
L
A
I
Site 51
S490
V
L
D
S
S
G
R
S
S
C
Y
H
P
N
G
Site 52
S491
L
D
S
S
G
R
S
S
C
Y
H
P
N
G
N
Site 53
Y493
S
S
G
R
S
S
C
Y
H
P
N
G
N
V
W
Site 54
S511
N
I
L
G
G
Q
Y
S
D
Q
A
G
N
R
I
Site 55
S524
R
I
R
A
W
N
W
S
N
S
I
T
S
S
P
Site 56
S526
R
A
W
N
W
S
N
S
I
T
S
S
P
F
V
Site 57
S530
W
S
N
S
I
T
S
S
P
F
V
S
F
K
P
Site 58
T559
E
Q
D
K
I
S
I
T
F
L
A
M
G
Q
Q
Site 59
S570
M
G
Q
Q
A
R
I
S
V
G
T
K
V
K
L
Site 60
T573
Q
A
R
I
S
V
G
T
K
V
K
L
P
N
P
Site 61
S619
G
C
V
N
F
P
S
S
Q
V
W
E
K
L
K
Site 62
S629
W
E
K
L
K
Q
P
S
Y
L
S
S
L
S
L
Site 63
Y630
E
K
L
K
Q
P
S
Y
L
S
S
L
S
L
K
Site 64
S633
K
Q
P
S
Y
L
S
S
L
S
L
K
L
I
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation