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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEP68
Full Name:
Centrosomal protein of 68 kDa
Alias:
Type:
Uncharacterized
Mass (Da):
81102
Number AA:
757
UniProt ID:
Q76N32
International Prot ID:
IPI00554739
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
E
K
A
E
A
E
A
S
E
D
T
K
A
Q
S
Site 2
S20
S
E
D
T
K
A
Q
S
Y
G
R
G
S
C
R
Site 3
Y21
E
D
T
K
A
Q
S
Y
G
R
G
S
C
R
E
Site 4
S25
A
Q
S
Y
G
R
G
S
C
R
E
R
E
L
D
Site 5
S38
L
D
I
P
G
P
M
S
G
E
Q
P
P
R
L
Site 6
S53
E
A
E
G
G
L
I
S
P
V
W
G
A
E
G
Site 7
T70
A
P
T
C
W
I
G
T
D
P
G
G
P
S
R
Site 8
S76
G
T
D
P
G
G
P
S
R
A
H
Q
P
Q
A
Site 9
S84
R
A
H
Q
P
Q
A
S
D
A
N
R
E
P
V
Site 10
S95
R
E
P
V
A
E
R
S
E
P
A
L
S
G
L
Site 11
S100
E
R
S
E
P
A
L
S
G
L
P
P
A
T
M
Site 12
T106
L
S
G
L
P
P
A
T
M
G
S
G
D
L
L
Site 13
S115
G
S
G
D
L
L
L
S
G
E
S
Q
V
E
K
Site 14
S118
D
L
L
L
S
G
E
S
Q
V
E
K
T
K
L
Site 15
T123
G
E
S
Q
V
E
K
T
K
L
S
S
S
E
E
Site 16
S126
Q
V
E
K
T
K
L
S
S
S
E
E
F
P
Q
Site 17
S127
V
E
K
T
K
L
S
S
S
E
E
F
P
Q
T
Site 18
S128
E
K
T
K
L
S
S
S
E
E
F
P
Q
T
L
Site 19
T134
S
S
E
E
F
P
Q
T
L
S
L
P
R
T
T
Site 20
S136
E
E
F
P
Q
T
L
S
L
P
R
T
T
T
I
Site 21
T140
Q
T
L
S
L
P
R
T
T
T
I
C
S
G
H
Site 22
T141
T
L
S
L
P
R
T
T
T
I
C
S
G
H
D
Site 23
T142
L
S
L
P
R
T
T
T
I
C
S
G
H
D
A
Site 24
T151
C
S
G
H
D
A
D
T
E
D
D
P
S
L
A
Site 25
S156
A
D
T
E
D
D
P
S
L
A
D
L
P
Q
A
Site 26
S167
L
P
Q
A
L
D
L
S
Q
Q
P
H
S
S
G
Site 27
S172
D
L
S
Q
Q
P
H
S
S
G
L
S
C
L
S
Site 28
S173
L
S
Q
Q
P
H
S
S
G
L
S
C
L
S
Q
Site 29
S176
Q
P
H
S
S
G
L
S
C
L
S
Q
W
K
S
Site 30
S179
S
S
G
L
S
C
L
S
Q
W
K
S
V
L
S
Site 31
S183
S
C
L
S
Q
W
K
S
V
L
S
P
G
S
A
Site 32
S186
S
Q
W
K
S
V
L
S
P
G
S
A
A
Q
P
Site 33
S189
K
S
V
L
S
P
G
S
A
A
Q
P
S
S
C
Site 34
S194
P
G
S
A
A
Q
P
S
S
C
S
I
S
A
S
Site 35
S195
G
S
A
A
Q
P
S
S
C
S
I
S
A
S
S
Site 36
S197
A
A
Q
P
S
S
C
S
I
S
A
S
S
T
G
Site 37
S199
Q
P
S
S
C
S
I
S
A
S
S
T
G
S
S
Site 38
S201
S
S
C
S
I
S
A
S
S
T
G
S
S
L
Q
Site 39
S202
S
C
S
I
S
A
S
S
T
G
S
S
L
Q
G
Site 40
T203
C
S
I
S
A
S
S
T
G
S
S
L
Q
G
H
Site 41
S205
I
S
A
S
S
T
G
S
S
L
Q
G
H
Q
E
Site 42
S206
S
A
S
S
T
G
S
S
L
Q
G
H
Q
E
R
Site 43
S220
R
A
E
P
R
G
G
S
L
A
K
V
S
S
S
Site 44
S238
V
V
P
Q
E
P
S
S
V
V
G
L
G
P
R
Site 45
S249
L
G
P
R
P
Q
W
S
P
Q
P
V
F
S
G
Site 46
S255
W
S
P
Q
P
V
F
S
G
G
D
A
S
G
L
Site 47
S260
V
F
S
G
G
D
A
S
G
L
G
R
R
R
L
Site 48
S268
G
L
G
R
R
R
L
S
F
Q
A
E
Y
W
A
Site 49
Y273
R
L
S
F
Q
A
E
Y
W
A
C
V
L
P
D
Site 50
S281
W
A
C
V
L
P
D
S
L
P
P
S
P
D
R
Site 51
S285
L
P
D
S
L
P
P
S
P
D
R
H
S
P
L
Site 52
S290
P
P
S
P
D
R
H
S
P
L
W
N
P
N
K
Site 53
Y305
E
Y
E
D
L
L
D
Y
T
Y
P
L
R
P
G
Site 54
T306
Y
E
D
L
L
D
Y
T
Y
P
L
R
P
G
P
Site 55
Y307
E
D
L
L
D
Y
T
Y
P
L
R
P
G
P
Q
Site 56
S321
Q
L
P
K
H
L
D
S
R
V
P
A
D
P
V
Site 57
S332
A
D
P
V
L
Q
D
S
G
V
D
L
D
S
F
Site 58
S338
D
S
G
V
D
L
D
S
F
S
V
S
P
A
S
Site 59
S342
D
L
D
S
F
S
V
S
P
A
S
T
L
K
S
Site 60
S345
S
F
S
V
S
P
A
S
T
L
K
S
P
T
N
Site 61
T346
F
S
V
S
P
A
S
T
L
K
S
P
T
N
V
Site 62
S349
S
P
A
S
T
L
K
S
P
T
N
V
S
P
N
Site 63
S354
L
K
S
P
T
N
V
S
P
N
C
P
P
A
E
Site 64
T363
N
C
P
P
A
E
A
T
A
L
P
F
S
G
P
Site 65
S368
E
A
T
A
L
P
F
S
G
P
R
E
P
S
L
Site 66
S374
F
S
G
P
R
E
P
S
L
K
Q
W
P
S
R
Site 67
S380
P
S
L
K
Q
W
P
S
R
V
P
Q
K
Q
G
Site 68
S393
Q
G
G
M
G
L
A
S
W
S
Q
L
A
S
T
Site 69
S395
G
M
G
L
A
S
W
S
Q
L
A
S
T
P
R
Site 70
S399
A
S
W
S
Q
L
A
S
T
P
R
A
P
G
S
Site 71
T400
S
W
S
Q
L
A
S
T
P
R
A
P
G
S
R
Site 72
S406
S
T
P
R
A
P
G
S
R
D
A
R
W
E
R
Site 73
T426
R
G
A
K
D
R
L
T
I
G
K
H
L
D
M
Site 74
S435
G
K
H
L
D
M
G
S
P
Q
L
R
T
R
D
Site 75
S447
T
R
D
R
G
W
P
S
P
R
P
E
R
E
K
Site 76
S457
P
E
R
E
K
R
T
S
Q
S
A
R
R
P
T
Site 77
S459
R
E
K
R
T
S
Q
S
A
R
R
P
T
C
T
Site 78
T464
S
Q
S
A
R
R
P
T
C
T
E
S
R
W
K
Site 79
T466
S
A
R
R
P
T
C
T
E
S
R
W
K
S
E
Site 80
S468
R
R
P
T
C
T
E
S
R
W
K
S
E
E
E
Site 81
S472
C
T
E
S
R
W
K
S
E
E
E
V
E
S
D
Site 82
S478
K
S
E
E
E
V
E
S
D
D
E
Y
L
A
L
Site 83
Y482
E
V
E
S
D
D
E
Y
L
A
L
P
A
R
L
Site 84
S493
P
A
R
L
T
Q
V
S
S
L
V
S
Y
L
G
Site 85
T510
S
T
L
V
T
L
P
T
G
D
I
K
G
Q
S
Site 86
S517
T
G
D
I
K
G
Q
S
P
L
E
V
S
D
S
Site 87
S522
G
Q
S
P
L
E
V
S
D
S
D
G
P
A
S
Site 88
S524
S
P
L
E
V
S
D
S
D
G
P
A
S
F
P
Site 89
S529
S
D
S
D
G
P
A
S
F
P
S
S
S
S
Q
Site 90
S532
D
G
P
A
S
F
P
S
S
S
S
Q
S
Q
L
Site 91
S533
G
P
A
S
F
P
S
S
S
S
Q
S
Q
L
P
Site 92
S534
P
A
S
F
P
S
S
S
S
Q
S
Q
L
P
P
Site 93
S535
A
S
F
P
S
S
S
S
Q
S
Q
L
P
P
G
Site 94
S537
F
P
S
S
S
S
Q
S
Q
L
P
P
G
A
A
Site 95
S548
P
G
A
A
L
Q
G
S
G
D
P
E
G
Q
N
Site 96
S561
Q
N
P
C
F
L
R
S
F
V
R
A
H
D
S
Site 97
S568
S
F
V
R
A
H
D
S
A
G
E
G
S
L
G
Site 98
S573
H
D
S
A
G
E
G
S
L
G
S
S
Q
A
L
Site 99
S577
G
E
G
S
L
G
S
S
Q
A
L
G
V
S
S
Site 100
T589
V
S
S
G
L
L
K
T
R
P
S
L
P
A
R
Site 101
S592
G
L
L
K
T
R
P
S
L
P
A
R
L
D
R
Site 102
S603
R
L
D
R
W
P
F
S
D
P
D
V
E
G
Q
Site 103
S622
G
G
E
Q
G
K
E
S
L
V
Q
C
V
K
T
Site 104
T648
L
Y
N
V
A
D
V
T
D
H
G
T
A
A
R
Site 105
T652
A
D
V
T
D
H
G
T
A
A
R
S
N
L
T
Site 106
S656
D
H
G
T
A
A
R
S
N
L
T
S
L
K
S
Site 107
T659
T
A
A
R
S
N
L
T
S
L
K
S
S
L
Q
Site 108
S660
A
A
R
S
N
L
T
S
L
K
S
S
L
Q
L
Site 109
S663
S
N
L
T
S
L
K
S
S
L
Q
L
Y
R
Q
Site 110
S664
N
L
T
S
L
K
S
S
L
Q
L
Y
R
Q
F
Site 111
Y668
L
K
S
S
L
Q
L
Y
R
Q
F
K
K
D
I
Site 112
S680
K
D
I
D
E
H
Q
S
L
T
E
S
V
L
Q
Site 113
T682
I
D
E
H
Q
S
L
T
E
S
V
L
Q
K
G
Site 114
S684
E
H
Q
S
L
T
E
S
V
L
Q
K
G
E
I
Site 115
S714
L
G
R
I
A
K
Q
S
G
E
L
E
S
H
A
Site 116
S719
K
Q
S
G
E
L
E
S
H
A
D
R
L
Y
D
Site 117
Y725
E
S
H
A
D
R
L
Y
D
S
I
L
A
S
L
Site 118
S727
H
A
D
R
L
Y
D
S
I
L
A
S
L
D
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation