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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BC060632
Full Name:
MTSS1-like protein
Alias:
ABBA-1; actin-bundling protein with BAIAP2y; LOC92154; metastasis suppressor 1-like
Type:
Actin binding protein
Mass (Da):
79929
Number AA:
747
UniProt ID:
Q765P7
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0017124
GO:0003779
GO:0008093
PhosphoSite+
KinaseNET
Biological Process:
GO:0046847
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y26
V
N
D
M
K
S
S
Y
P
I
W
E
D
F
N
Site 2
S34
P
I
W
E
D
F
N
S
K
A
T
K
L
H
S
Site 3
S41
S
K
A
T
K
L
H
S
Q
L
R
T
T
V
L
Site 4
T65
Q
K
V
A
D
M
A
T
N
T
R
G
A
T
R
Site 5
T71
A
T
N
T
R
G
A
T
R
D
I
G
S
A
L
Site 6
S87
R
M
C
M
R
H
R
S
I
E
T
K
L
R
Q
Site 7
T96
E
T
K
L
R
Q
F
T
N
A
L
L
E
S
L
Site 8
Y129
D
K
D
H
A
K
E
Y
K
R
A
R
H
E
I
Site 9
S140
R
H
E
I
K
K
K
S
S
D
T
L
K
L
Q
Site 10
S141
H
E
I
K
K
K
S
S
D
T
L
K
L
Q
K
Site 11
T143
I
K
K
K
S
S
D
T
L
K
L
Q
K
K
A
Site 12
S166
D
L
Q
P
Q
L
D
S
A
L
Q
D
V
N
D
Site 13
Y175
L
Q
D
V
N
D
M
Y
L
L
L
E
E
T
E
Site 14
T199
E
E
R
G
R
F
C
T
F
I
T
F
L
Q
P
Site 15
S242
P
H
K
L
P
P
A
S
E
Q
V
I
K
D
L
Site 16
Y254
K
D
L
K
G
S
D
Y
S
W
S
Y
Q
T
P
Site 17
S255
D
L
K
G
S
D
Y
S
W
S
Y
Q
T
P
P
Site 18
S257
K
G
S
D
Y
S
W
S
Y
Q
T
P
P
S
S
Site 19
Y258
G
S
D
Y
S
W
S
Y
Q
T
P
P
S
S
P
Site 20
T260
D
Y
S
W
S
Y
Q
T
P
P
S
S
P
S
S
Site 21
S263
W
S
Y
Q
T
P
P
S
S
P
S
S
S
S
S
Site 22
S264
S
Y
Q
T
P
P
S
S
P
S
S
S
S
S
R
Site 23
S266
Q
T
P
P
S
S
P
S
S
S
S
S
R
K
S
Site 24
S267
T
P
P
S
S
P
S
S
S
S
S
R
K
S
S
Site 25
S268
P
P
S
S
P
S
S
S
S
S
R
K
S
S
M
Site 26
S269
P
S
S
P
S
S
S
S
S
R
K
S
S
M
C
Site 27
S270
S
S
P
S
S
S
S
S
R
K
S
S
M
C
S
Site 28
S273
S
S
S
S
S
R
K
S
S
M
C
S
A
P
S
Site 29
S274
S
S
S
S
R
K
S
S
M
C
S
A
P
S
S
Site 30
S277
S
R
K
S
S
M
C
S
A
P
S
S
S
S
S
Site 31
S280
S
S
M
C
S
A
P
S
S
S
S
S
A
K
G
Site 32
S281
S
M
C
S
A
P
S
S
S
S
S
A
K
G
G
Site 33
S282
M
C
S
A
P
S
S
S
S
S
A
K
G
G
G
Site 34
S284
S
A
P
S
S
S
S
S
A
K
G
G
G
A
P
Site 35
T298
P
W
P
G
G
A
Q
T
Y
S
P
S
S
T
C
Site 36
S300
P
G
G
A
Q
T
Y
S
P
S
S
T
C
R
Y
Site 37
S303
A
Q
T
Y
S
P
S
S
T
C
R
Y
R
S
L
Site 38
T304
Q
T
Y
S
P
S
S
T
C
R
Y
R
S
L
A
Site 39
Y307
S
P
S
S
T
C
R
Y
R
S
L
A
Q
P
A
Site 40
S309
S
S
T
C
R
Y
R
S
L
A
Q
P
A
T
T
Site 41
T315
R
S
L
A
Q
P
A
T
T
T
A
R
L
S
S
Site 42
S321
A
T
T
T
A
R
L
S
S
V
S
S
H
D
S
Site 43
S322
T
T
T
A
R
L
S
S
V
S
S
H
D
S
G
Site 44
S324
T
A
R
L
S
S
V
S
S
H
D
S
G
F
V
Site 45
S325
A
R
L
S
S
V
S
S
H
D
S
G
F
V
S
Site 46
S328
S
S
V
S
S
H
D
S
G
F
V
S
Q
D
A
Site 47
S332
S
H
D
S
G
F
V
S
Q
D
A
T
Y
S
K
Site 48
T336
G
F
V
S
Q
D
A
T
Y
S
K
P
P
S
P
Site 49
Y337
F
V
S
Q
D
A
T
Y
S
K
P
P
S
P
M
Site 50
S338
V
S
Q
D
A
T
Y
S
K
P
P
S
P
M
P
Site 51
S342
A
T
Y
S
K
P
P
S
P
M
P
S
D
I
T
Site 52
S346
K
P
P
S
P
M
P
S
D
I
T
S
Q
K
S
Site 53
T349
S
P
M
P
S
D
I
T
S
Q
K
S
S
S
S
Site 54
S350
P
M
P
S
D
I
T
S
Q
K
S
S
S
S
A
Site 55
S353
S
D
I
T
S
Q
K
S
S
S
S
A
S
S
E
Site 56
S354
D
I
T
S
Q
K
S
S
S
S
A
S
S
E
A
Site 57
S355
I
T
S
Q
K
S
S
S
S
A
S
S
E
A
S
Site 58
S356
T
S
Q
K
S
S
S
S
A
S
S
E
A
S
E
Site 59
S358
Q
K
S
S
S
S
A
S
S
E
A
S
E
T
C
Site 60
S359
K
S
S
S
S
A
S
S
E
A
S
E
T
C
Q
Site 61
S362
S
S
A
S
S
E
A
S
E
T
C
Q
S
V
S
Site 62
T364
A
S
S
E
A
S
E
T
C
Q
S
V
S
E
C
Site 63
S367
E
A
S
E
T
C
Q
S
V
S
E
C
S
S
P
Site 64
S369
S
E
T
C
Q
S
V
S
E
C
S
S
P
T
S
Site 65
S372
C
Q
S
V
S
E
C
S
S
P
T
S
D
W
S
Site 66
S373
Q
S
V
S
E
C
S
S
P
T
S
D
W
S
K
Site 67
S376
S
E
C
S
S
P
T
S
D
W
S
K
V
G
S
Site 68
S379
S
S
P
T
S
D
W
S
K
V
G
S
H
E
Q
Site 69
S383
S
D
W
S
K
V
G
S
H
E
Q
P
S
G
A
Site 70
S388
V
G
S
H
E
Q
P
S
G
A
T
L
Q
R
R
Site 71
T405
R
V
E
L
L
R
D
T
E
P
G
P
A
S
G
Site 72
S411
D
T
E
P
G
P
A
S
G
G
T
L
G
P
S
Site 73
T414
P
G
P
A
S
G
G
T
L
G
P
S
G
E
E
Site 74
S418
S
G
G
T
L
G
P
S
G
E
E
A
P
R
P
Site 75
S428
E
A
P
R
P
R
M
S
P
A
T
I
A
A
K
Site 76
T431
R
P
R
M
S
P
A
T
I
A
A
K
H
G
E
Site 77
S441
A
K
H
G
E
E
V
S
P
A
A
S
D
L
A
Site 78
S456
M
V
L
T
R
G
L
S
L
E
H
Q
K
S
S
Site 79
S462
L
S
L
E
H
Q
K
S
S
R
D
S
L
Q
Y
Site 80
S463
S
L
E
H
Q
K
S
S
R
D
S
L
Q
Y
S
Site 81
S466
H
Q
K
S
S
R
D
S
L
Q
Y
S
S
G
Y
Site 82
Y469
S
S
R
D
S
L
Q
Y
S
S
G
Y
S
T
Q
Site 83
S470
S
R
D
S
L
Q
Y
S
S
G
Y
S
T
Q
T
Site 84
S474
L
Q
Y
S
S
G
Y
S
T
Q
T
T
T
P
S
Site 85
T475
Q
Y
S
S
G
Y
S
T
Q
T
T
T
P
S
C
Site 86
T477
S
S
G
Y
S
T
Q
T
T
T
P
S
C
S
E
Site 87
T478
S
G
Y
S
T
Q
T
T
T
P
S
C
S
E
D
Site 88
T479
G
Y
S
T
Q
T
T
T
P
S
C
S
E
D
T
Site 89
S483
Q
T
T
T
P
S
C
S
E
D
T
I
P
S
Q
Site 90
T486
T
P
S
C
S
E
D
T
I
P
S
Q
G
S
D
Site 91
S492
D
T
I
P
S
Q
G
S
D
Y
D
C
Y
S
V
Site 92
Y494
I
P
S
Q
G
S
D
Y
D
C
Y
S
V
N
G
Site 93
Y497
Q
G
S
D
Y
D
C
Y
S
V
N
G
D
A
D
Site 94
S498
G
S
D
Y
D
C
Y
S
V
N
G
D
A
D
S
Site 95
S505
S
V
N
G
D
A
D
S
E
G
P
P
E
F
D
Site 96
S514
G
P
P
E
F
D
K
S
S
T
I
P
R
N
S
Site 97
S515
P
P
E
F
D
K
S
S
T
I
P
R
N
S
N
Site 98
T516
P
E
F
D
K
S
S
T
I
P
R
N
S
N
I
Site 99
S521
S
S
T
I
P
R
N
S
N
I
A
Q
N
Y
R
Site 100
Y527
N
S
N
I
A
Q
N
Y
R
R
L
I
Q
T
K
Site 101
T533
N
Y
R
R
L
I
Q
T
K
R
P
A
S
T
A
Site 102
S538
I
Q
T
K
R
P
A
S
T
A
G
L
P
T
A
Site 103
T539
Q
T
K
R
P
A
S
T
A
G
L
P
T
A
G
Site 104
T544
A
S
T
A
G
L
P
T
A
G
L
P
T
A
T
Site 105
T563
G
A
P
P
G
V
A
T
I
R
R
T
P
S
T
Site 106
T567
G
V
A
T
I
R
R
T
P
S
T
K
P
T
V
Site 107
S569
A
T
I
R
R
T
P
S
T
K
P
T
V
R
R
Site 108
T570
T
I
R
R
T
P
S
T
K
P
T
V
R
R
A
Site 109
T573
R
T
P
S
T
K
P
T
V
R
R
A
L
S
S
Site 110
S579
P
T
V
R
R
A
L
S
S
A
G
P
I
P
I
Site 111
S580
T
V
R
R
A
L
S
S
A
G
P
I
P
I
R
Site 112
T595
P
P
I
V
P
V
K
T
P
T
V
P
D
S
P
Site 113
T597
I
V
P
V
K
T
P
T
V
P
D
S
P
G
Y
Site 114
S601
K
T
P
T
V
P
D
S
P
G
Y
M
G
P
T
Site 115
Y604
T
V
P
D
S
P
G
Y
M
G
P
T
R
A
G
Site 116
T608
S
P
G
Y
M
G
P
T
R
A
G
S
E
E
C
Site 117
S612
M
G
P
T
R
A
G
S
E
E
C
V
F
Y
T
Site 118
Y618
G
S
E
E
C
V
F
Y
T
D
E
T
A
S
P
Site 119
T622
C
V
F
Y
T
D
E
T
A
S
P
L
A
P
D
Site 120
S624
F
Y
T
D
E
T
A
S
P
L
A
P
D
L
A
Site 121
S634
A
P
D
L
A
K
A
S
P
K
R
L
S
L
P
Site 122
S639
K
A
S
P
K
R
L
S
L
P
N
T
A
W
G
Site 123
T643
K
R
L
S
L
P
N
T
A
W
G
S
P
S
P
Site 124
S647
L
P
N
T
A
W
G
S
P
S
P
E
A
A
G
Site 125
S649
N
T
A
W
G
S
P
S
P
E
A
A
G
Y
P
Site 126
Y655
P
S
P
E
A
A
G
Y
P
G
A
G
A
E
D
Site 127
S673
Q
L
A
A
N
R
H
S
L
V
E
K
L
G
E
Site 128
S700
F
P
F
P
T
A
L
S
A
T
P
T
E
E
T
Site 129
T702
F
P
T
A
L
S
A
T
P
T
E
E
T
P
T
Site 130
T704
T
A
L
S
A
T
P
T
E
E
T
P
T
P
P
Site 131
T707
S
A
T
P
T
E
E
T
P
T
P
P
P
A
A
Site 132
T709
T
P
T
E
E
T
P
T
P
P
P
A
A
T
S
Site 133
S716
T
P
P
P
A
A
T
S
D
P
P
A
E
D
M
Site 134
T736
R
G
V
R
L
R
R
T
V
T
N
D
R
S
A
Site 135
T738
V
R
L
R
R
T
V
T
N
D
R
S
A
P
R
Site 136
S742
R
T
V
T
N
D
R
S
A
P
R
I
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation