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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PGAP1
Full Name:
GPI inositol-deacylase
Alias:
Post-GPI attachment to proteins factor 1
Type:
Mass (Da):
105383
Number AA:
922
UniProt ID:
Q75T13
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
E
N
K
C
S
M
S
Y
M
F
E
Y
P
E
Y
Site 2
Y45
S
M
S
Y
M
F
E
Y
P
E
Y
Q
K
I
E
Site 3
Y48
Y
M
F
E
Y
P
E
Y
Q
K
I
E
L
P
K
Site 4
Y61
P
K
K
L
A
K
R
Y
P
A
Y
E
L
Y
L
Site 5
Y64
L
A
K
R
Y
P
A
Y
E
L
Y
L
Y
G
E
Site 6
Y67
R
Y
P
A
Y
E
L
Y
L
Y
G
E
G
S
Y
Site 7
Y69
P
A
Y
E
L
Y
L
Y
G
E
G
S
Y
A
E
Site 8
S73
L
Y
L
Y
G
E
G
S
Y
A
E
E
H
K
I
Site 9
S97
F
L
P
G
N
A
G
S
Y
K
Q
V
R
S
I
Site 10
Y98
L
P
G
N
A
G
S
Y
K
Q
V
R
S
I
G
Site 11
S103
G
S
Y
K
Q
V
R
S
I
G
S
I
A
L
R
Site 12
Y119
A
E
D
I
D
F
K
Y
H
F
D
F
F
S
V
Site 13
T144
G
G
S
L
Q
K
Q
T
K
F
V
H
E
C
I
Site 14
S167
G
Q
E
F
A
P
K
S
V
A
I
I
G
H
S
Site 15
T216
M
P
L
D
R
F
I
T
D
F
Y
T
T
V
N
Site 16
Y219
D
R
F
I
T
D
F
Y
T
T
V
N
N
Y
W
Site 17
Y247
V
A
G
G
F
R
D
Y
Q
V
R
S
G
L
T
Site 18
T254
Y
Q
V
R
S
G
L
T
F
L
P
K
L
S
H
Site 19
S264
P
K
L
S
H
H
T
S
A
L
S
V
V
S
S
Site 20
T276
V
S
S
A
V
P
K
T
W
V
S
T
D
H
L
Site 21
T307
F
D
L
I
D
A
D
T
K
Q
I
T
Q
N
S
Site 22
S314
T
K
Q
I
T
Q
N
S
K
K
K
L
S
V
L
Site 23
S319
Q
N
S
K
K
K
L
S
V
L
Y
H
H
F
I
Site 24
Y322
K
K
K
L
S
V
L
Y
H
H
F
I
R
H
P
Site 25
Y359
V
K
V
S
K
W
T
Y
V
A
Y
N
E
S
E
Site 26
Y362
S
K
W
T
Y
V
A
Y
N
E
S
E
K
I
Y
Site 27
Y369
Y
N
E
S
E
K
I
Y
F
T
F
P
L
E
N
Site 28
T371
E
S
E
K
I
Y
F
T
F
P
L
E
N
H
R
Site 29
Y381
L
E
N
H
R
K
I
Y
T
H
V
Y
C
Q
S
Site 30
Y385
R
K
I
Y
T
H
V
Y
C
Q
S
T
M
L
D
Site 31
T422
W
K
A
E
L
L
P
T
I
K
Y
L
T
L
R
Site 32
Y425
E
L
L
P
T
I
K
Y
L
T
L
R
L
Q
D
Site 33
T427
L
P
T
I
K
Y
L
T
L
R
L
Q
D
Y
P
Site 34
S449
Y
V
P
S
V
R
G
S
K
F
V
V
D
C
E
Site 35
S522
A
V
K
E
E
I
T
S
I
Y
R
L
H
I
P
Site 36
Y524
K
E
E
I
T
S
I
Y
R
L
H
I
P
W
S
Site 37
S531
Y
R
L
H
I
P
W
S
Y
E
D
S
L
T
I
Site 38
S535
I
P
W
S
Y
E
D
S
L
T
I
A
Q
A
P
Site 39
T537
W
S
Y
E
D
S
L
T
I
A
Q
A
P
S
S
Site 40
S548
A
P
S
S
T
E
I
S
L
K
L
H
I
A
Q
Site 41
Y575
Y
T
S
S
D
C
R
Y
E
V
T
V
K
T
S
Site 42
T578
S
D
C
R
Y
E
V
T
V
K
T
S
F
S
Q
Site 43
S582
Y
E
V
T
V
K
T
S
F
S
Q
I
L
G
Q
Site 44
Y601
H
G
G
A
L
P
A
Y
V
V
S
N
I
L
L
Site 45
Y610
V
S
N
I
L
L
A
Y
R
G
Q
L
Y
S
L
Site 46
Y626
S
T
G
C
C
L
E
Y
A
T
M
L
D
K
E
Site 47
Y637
L
D
K
E
A
K
P
Y
K
V
D
P
F
V
I
Site 48
S719
W
L
A
L
K
R
P
S
E
L
P
K
D
I
K
Site 49
S729
P
K
D
I
K
M
I
S
P
D
L
P
F
L
T
Site 50
S769
K
V
V
H
L
Q
A
S
L
T
T
F
K
N
S
Site 51
T771
V
H
L
Q
A
S
L
T
T
F
K
N
S
Q
P
Site 52
T772
H
L
Q
A
S
L
T
T
F
K
N
S
Q
P
V
Site 53
S776
S
L
T
T
F
K
N
S
Q
P
V
N
P
K
H
Site 54
S784
Q
P
V
N
P
K
H
S
R
R
S
E
K
K
S
Site 55
S787
N
P
K
H
S
R
R
S
E
K
K
S
N
H
H
Site 56
S791
S
R
R
S
E
K
K
S
N
H
H
K
D
S
S
Site 57
S797
K
S
N
H
H
K
D
S
S
I
H
H
L
R
L
Site 58
S798
S
N
H
H
K
D
S
S
I
H
H
L
R
L
S
Site 59
S805
S
I
H
H
L
R
L
S
A
N
D
A
E
D
S
Site 60
S812
S
A
N
D
A
E
D
S
L
R
M
H
S
T
V
Site 61
S817
E
D
S
L
R
M
H
S
T
V
I
N
L
L
T
Site 62
Y844
W
L
K
N
L
R
Y
Y
F
K
L
N
P
D
P
Site 63
T871
A
I
L
G
N
T
Y
T
V
S
I
K
S
S
K
Site 64
S877
Y
T
V
S
I
K
S
S
K
L
L
K
T
T
S
Site 65
T882
K
S
S
K
L
L
K
T
T
S
Q
F
P
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation