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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CBLL1
Full Name:
E3 ubiquitin-protein ligase Hakai
Alias:
EC 6.3.2.-; Hakai
Type:
Mass (Da):
54519
Number AA:
491
UniProt ID:
Q75N03
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000151
GO:0005622
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004842
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0016337
GO:0019941
GO:0007162
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
T
D
N
E
L
Q
G
T
N
S
S
G
S
L
G
Site 2
S13
N
E
L
Q
G
T
N
S
S
G
S
L
G
G
L
Site 3
S14
E
L
Q
G
T
N
S
S
G
S
L
G
G
L
D
Site 4
S16
Q
G
T
N
S
S
G
S
L
G
G
L
D
V
R
Site 5
T44
K
A
K
P
A
P
R
T
Q
R
T
I
N
R
M
Site 6
Y65
G
D
E
E
G
F
D
Y
N
E
E
E
R
Y
D
Site 7
Y71
D
Y
N
E
E
E
R
Y
D
C
K
G
G
E
L
Site 8
T104
I
L
G
E
K
D
D
T
P
V
H
F
C
D
K
Site 9
Y119
C
G
L
P
I
K
I
Y
G
R
M
I
P
C
K
Site 10
S149
D
K
M
C
P
G
C
S
D
P
V
Q
R
I
E
Site 11
T159
V
Q
R
I
E
Q
C
T
R
G
S
L
F
M
C
Site 12
Y176
V
Q
G
C
K
R
T
Y
L
S
Q
R
D
L
Q
Site 13
S178
G
C
K
R
T
Y
L
S
Q
R
D
L
Q
A
H
Site 14
S201
G
K
P
V
T
R
A
S
L
E
N
V
H
P
P
Site 15
T214
P
P
I
A
P
P
P
T
E
I
P
E
R
F
I
Site 16
Y253
Q
H
V
P
H
E
H
Y
N
Q
P
H
E
D
I
Site 17
S268
R
A
P
P
A
E
L
S
M
A
P
P
P
P
R
Site 18
S276
M
A
P
P
P
P
R
S
V
S
Q
E
T
F
R
Site 19
S278
P
P
P
P
R
S
V
S
Q
E
T
F
R
I
S
Site 20
T281
P
R
S
V
S
Q
E
T
F
R
I
S
T
R
K
Site 21
S285
S
Q
E
T
F
R
I
S
T
R
K
H
S
N
L
Site 22
T286
Q
E
T
F
R
I
S
T
R
K
H
S
N
L
I
Site 23
S290
R
I
S
T
R
K
H
S
N
L
I
T
V
P
I
Site 24
T294
R
K
H
S
N
L
I
T
V
P
I
Q
D
D
S
Site 25
S301
T
V
P
I
Q
D
D
S
N
S
G
A
R
E
P
Site 26
S303
P
I
Q
D
D
S
N
S
G
A
R
E
P
P
P
Site 27
Y322
P
A
H
H
H
P
E
Y
Q
G
Q
P
V
V
S
Site 28
Y341
I
M
P
P
Q
Q
H
Y
A
P
P
P
P
P
P
Site 29
S352
P
P
P
P
P
P
I
S
H
P
M
P
H
P
P
Site 30
T364
H
P
P
Q
A
A
G
T
P
H
L
V
Y
S
Q
Site 31
Y369
A
G
T
P
H
L
V
Y
S
Q
A
P
P
P
P
Site 32
S370
G
T
P
H
L
V
Y
S
Q
A
P
P
P
P
M
Site 33
T378
Q
A
P
P
P
P
M
T
S
A
P
P
P
I
T
Site 34
S379
A
P
P
P
P
M
T
S
A
P
P
P
I
T
P
Site 35
T385
T
S
A
P
P
P
I
T
P
P
P
G
H
I
I
Site 36
Y398
I
I
A
Q
M
P
P
Y
M
N
H
P
P
P
G
Site 37
T417
Q
H
G
G
P
P
V
T
A
P
P
P
H
H
Y
Site 38
Y424
T
A
P
P
P
H
H
Y
N
P
N
S
L
P
Q
Site 39
S428
P
H
H
Y
N
P
N
S
L
P
Q
F
T
E
D
Site 40
T438
Q
F
T
E
D
Q
G
T
L
S
P
P
F
T
Q
Site 41
S440
T
E
D
Q
G
T
L
S
P
P
F
T
Q
P
G
Site 42
T444
G
T
L
S
P
P
F
T
Q
P
G
G
M
S
P
Site 43
S450
F
T
Q
P
G
G
M
S
P
G
I
W
P
A
P
Site 44
S471
P
R
L
Q
G
P
P
S
Q
T
P
L
P
G
P
Site 45
T473
L
Q
G
P
P
S
Q
T
P
L
P
G
P
H
H
Site 46
T484
G
P
H
H
P
D
Q
T
R
Y
R
P
Y
Y
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation