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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FRA10AC1
Full Name:
Protein FRA10AC1
Alias:
F10C1; Fragile site 10q23.3
Type:
Unknown function
Mass (Da):
37584
Number AA:
315
UniProt ID:
Q70Z53
International Prot ID:
IPI00425669
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
H
G
H
G
G
Y
D
S
D
F
S
D
D
Site 2
S9
H
G
H
G
G
Y
D
S
D
F
S
D
D
E
H
Site 3
S12
G
G
Y
D
S
D
F
S
D
D
E
H
C
G
E
Site 4
S21
D
E
H
C
G
E
S
S
K
R
K
K
R
T
V
Site 5
T27
S
S
K
R
K
K
R
T
V
E
D
D
L
L
L
Site 6
Y74
H
L
I
A
M
D
A
Y
Q
R
H
R
K
F
V
Site 7
Y84
H
R
K
F
V
N
D
Y
I
L
Y
Y
G
G
K
Site 8
Y87
F
V
N
D
Y
I
L
Y
Y
G
G
K
K
E
D
Site 9
Y88
V
N
D
Y
I
L
Y
Y
G
G
K
K
E
D
F
Site 10
T104
R
L
G
E
N
D
K
T
D
L
D
V
I
R
E
Site 11
T126
E
E
D
E
M
D
M
T
W
E
K
R
L
A
K
Site 12
Y135
E
K
R
L
A
K
K
Y
Y
D
K
L
F
K
E
Site 13
Y136
K
R
L
A
K
K
Y
Y
D
K
L
F
K
E
Y
Site 14
Y151
C
I
A
D
L
S
K
Y
K
E
N
K
F
G
F
Site 15
Y179
Q
F
F
C
G
N
K
Y
C
D
K
K
E
G
L
Site 16
S188
D
K
K
E
G
L
K
S
W
E
V
N
F
G
Y
Site 17
Y195
S
W
E
V
N
F
G
Y
I
E
H
G
E
K
R
Site 18
S229
H
R
R
K
E
I
K
S
K
K
R
K
D
K
T
Site 19
T236
S
K
K
R
K
D
K
T
K
K
D
C
E
E
S
Site 20
S243
T
K
K
D
C
E
E
S
S
H
K
K
S
R
L
Site 21
S244
K
K
D
C
E
E
S
S
H
K
K
S
R
L
S
Site 22
S248
E
E
S
S
H
K
K
S
R
L
S
S
A
E
E
Site 23
S251
S
H
K
K
S
R
L
S
S
A
E
E
A
S
K
Site 24
S252
H
K
K
S
R
L
S
S
A
E
E
A
S
K
K
Site 25
S257
L
S
S
A
E
E
A
S
K
K
K
D
K
G
H
Site 26
S265
K
K
K
D
K
G
H
S
S
S
K
K
S
E
D
Site 27
S266
K
K
D
K
G
H
S
S
S
K
K
S
E
D
S
Site 28
S267
K
D
K
G
H
S
S
S
K
K
S
E
D
S
L
Site 29
S270
G
H
S
S
S
K
K
S
E
D
S
L
L
R
N
Site 30
S273
S
S
K
K
S
E
D
S
L
L
R
N
S
D
E
Site 31
S278
E
D
S
L
L
R
N
S
D
E
E
E
S
A
S
Site 32
S283
R
N
S
D
E
E
E
S
A
S
E
S
E
L
W
Site 33
S285
S
D
E
E
E
S
A
S
E
S
E
L
W
K
G
Site 34
S287
E
E
E
S
A
S
E
S
E
L
W
K
G
P
L
Site 35
T297
W
K
G
P
L
P
E
T
D
E
K
S
Q
E
E
Site 36
S301
L
P
E
T
D
E
K
S
Q
E
E
E
F
D
E
Site 37
Y309
Q
E
E
E
F
D
E
Y
F
Q
D
L
F
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation