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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IKIP
Full Name:
Inhibitor of nuclear factor kappa-B kinase-interacting protein
Alias:
FLJ31051; i kappa b kinase interacting protein; IKBKB interacting protein; ikip; ikip1; IKK interacting protein
Type:
Adaptor/scaffold
Mass (Da):
39290
Number AA:
350
UniProt ID:
Q70UQ0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006917
GO:0010165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
E
V
K
S
R
K
K
S
G
P
K
Site 2
S10
E
V
K
S
R
K
K
S
G
P
K
G
A
P
A
Site 3
S24
A
A
E
P
G
K
R
S
E
G
G
K
T
P
V
Site 4
T29
K
R
S
E
G
G
K
T
P
V
A
R
S
S
G
Site 5
S34
G
K
T
P
V
A
R
S
S
G
G
G
G
W
A
Site 6
S35
K
T
P
V
A
R
S
S
G
G
G
G
W
A
D
Site 7
S91
N
E
F
Q
Q
L
Q
S
K
I
S
L
I
S
E
Site 8
S94
Q
Q
L
Q
S
K
I
S
L
I
S
E
K
W
Q
Site 9
S103
I
S
E
K
W
Q
K
S
E
A
I
M
E
Q
L
Site 10
T137
K
T
W
S
N
R
I
T
E
K
Q
D
I
L
N
Site 11
S146
K
Q
D
I
L
N
N
S
L
T
T
L
S
Q
D
Site 12
T148
D
I
L
N
N
S
L
T
T
L
S
Q
D
I
T
Site 13
S151
N
N
S
L
T
T
L
S
Q
D
I
T
K
V
D
Site 14
T155
T
T
L
S
Q
D
I
T
K
V
D
Q
S
T
T
Site 15
T177
L
K
I
T
S
V
K
T
D
I
R
R
I
S
G
Site 16
S183
K
T
D
I
R
R
I
S
G
L
V
T
D
V
I
Site 17
T187
R
R
I
S
G
L
V
T
D
V
I
S
L
T
D
Site 18
S191
G
L
V
T
D
V
I
S
L
T
D
S
V
Q
E
Site 19
T193
V
T
D
V
I
S
L
T
D
S
V
Q
E
L
E
Site 20
S195
D
V
I
S
L
T
D
S
V
Q
E
L
E
N
K
Site 21
S219
K
N
I
G
D
L
L
S
S
S
I
D
R
T
A
Site 22
S220
N
I
G
D
L
L
S
S
S
I
D
R
T
A
T
Site 23
S221
I
G
D
L
L
S
S
S
I
D
R
T
A
T
L
Site 24
T225
L
S
S
S
I
D
R
T
A
T
L
R
K
T
A
Site 25
T227
S
S
I
D
R
T
A
T
L
R
K
T
A
S
E
Site 26
T231
R
T
A
T
L
R
K
T
A
S
E
N
S
Q
R
Site 27
S233
A
T
L
R
K
T
A
S
E
N
S
Q
R
I
N
Site 28
S236
R
K
T
A
S
E
N
S
Q
R
I
N
S
V
K
Site 29
S241
E
N
S
Q
R
I
N
S
V
K
K
T
L
T
E
Site 30
T245
R
I
N
S
V
K
K
T
L
T
E
L
K
S
D
Site 31
T247
N
S
V
K
K
T
L
T
E
L
K
S
D
F
D
Site 32
S251
K
T
L
T
E
L
K
S
D
F
D
K
H
T
D
Site 33
T257
K
S
D
F
D
K
H
T
D
R
F
L
S
L
E
Site 34
S262
K
H
T
D
R
F
L
S
L
E
G
D
R
A
K
Site 35
T273
D
R
A
K
V
L
K
T
V
T
F
A
N
D
L
Site 36
S292
Y
N
L
K
K
D
F
S
R
L
E
P
L
V
N
Site 37
T310
L
R
I
G
R
L
V
T
D
L
L
Q
R
E
K
Site 38
S323
E
K
E
I
A
F
L
S
E
K
I
S
N
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation