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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CREB3L2
Full Name:
Cyclic AMP-responsive element-binding protein 3-like protein 2
Alias:
BBF2 human homologue on chromosome 7; BBF2H7; CR3L2
Type:
Transcription protein
Mass (Da):
57429
Number AA:
520
UniProt ID:
Q70SY1
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0046983
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006986
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
V
L
E
S
G
E
Q
G
V
L
Q
Site 2
S19
L
Q
W
D
R
K
L
S
E
L
S
E
P
G
D
Site 3
S22
D
R
K
L
S
E
L
S
E
P
G
D
G
E
A
Site 4
Y32
G
D
G
E
A
L
M
Y
H
T
H
F
S
E
L
Site 5
S44
S
E
L
L
D
E
F
S
Q
N
V
L
G
Q
L
Site 6
S58
L
L
N
D
P
F
L
S
E
K
S
V
S
M
E
Site 7
S61
D
P
F
L
S
E
K
S
V
S
M
E
V
E
P
Site 8
S63
F
L
S
E
K
S
V
S
M
E
V
E
P
S
P
Site 9
S69
V
S
M
E
V
E
P
S
P
T
S
P
A
P
L
Site 10
T71
M
E
V
E
P
S
P
T
S
P
A
P
L
I
Q
Site 11
S72
E
V
E
P
S
P
T
S
P
A
P
L
I
Q
A
Site 12
S84
I
Q
A
E
H
S
Y
S
L
C
E
E
P
R
A
Site 13
S93
C
E
E
P
R
A
Q
S
P
F
T
H
I
T
T
Site 14
T96
P
R
A
Q
S
P
F
T
H
I
T
T
S
D
S
Site 15
T99
Q
S
P
F
T
H
I
T
T
S
D
S
F
N
D
Site 16
S101
P
F
T
H
I
T
T
S
D
S
F
N
D
D
E
Site 17
S103
T
H
I
T
T
S
D
S
F
N
D
D
E
V
E
Site 18
Y115
E
V
E
S
E
K
W
Y
L
S
T
D
F
P
S
Site 19
S117
E
S
E
K
W
Y
L
S
T
D
F
P
S
T
S
Site 20
T118
S
E
K
W
Y
L
S
T
D
F
P
S
T
S
I
Site 21
S122
Y
L
S
T
D
F
P
S
T
S
I
K
T
E
P
Site 22
T131
S
I
K
T
E
P
I
T
D
E
P
P
P
G
L
Site 23
T151
L
T
I
T
A
I
S
T
P
L
E
K
E
E
P
Site 24
T164
E
P
P
L
E
M
N
T
G
V
D
S
S
C
Q
Site 25
S168
E
M
N
T
G
V
D
S
S
C
Q
T
I
I
P
Site 26
S169
M
N
T
G
V
D
S
S
C
Q
T
I
I
P
K
Site 27
S191
V
D
Q
F
L
N
F
S
P
K
E
A
P
V
D
Site 28
T205
D
H
L
H
L
P
P
T
P
P
S
S
H
G
S
Site 29
S208
H
L
P
P
T
P
P
S
S
H
G
S
D
S
E
Site 30
S209
L
P
P
T
P
P
S
S
H
G
S
D
S
E
G
Site 31
S212
T
P
P
S
S
H
G
S
D
S
E
G
S
L
S
Site 32
S214
P
S
S
H
G
S
D
S
E
G
S
L
S
P
N
Site 33
S217
H
G
S
D
S
E
G
S
L
S
P
N
P
R
L
Site 34
S219
S
D
S
E
G
S
L
S
P
N
P
R
L
H
P
Site 35
S228
N
P
R
L
H
P
F
S
L
P
Q
T
H
S
P
Site 36
T232
H
P
F
S
L
P
Q
T
H
S
P
S
R
A
A
Site 37
S234
F
S
L
P
Q
T
H
S
P
S
R
A
A
P
R
Site 38
S244
R
A
A
P
R
A
P
S
A
L
S
S
S
P
L
Site 39
S247
P
R
A
P
S
A
L
S
S
S
P
L
L
T
A
Site 40
S248
R
A
P
S
A
L
S
S
S
P
L
L
T
A
P
Site 41
T253
L
S
S
S
P
L
L
T
A
P
H
K
L
Q
G
Site 42
S261
A
P
H
K
L
Q
G
S
G
P
L
V
L
T
E
Site 43
T267
G
S
G
P
L
V
L
T
E
E
E
K
R
T
L
Site 44
T273
L
T
E
E
E
K
R
T
L
I
A
E
G
Y
P
Site 45
Y279
R
T
L
I
A
E
G
Y
P
I
P
T
K
L
P
Site 46
S288
I
P
T
K
L
P
L
S
K
S
E
E
K
A
L
Site 47
S290
T
K
L
P
L
S
K
S
E
E
K
A
L
K
K
Site 48
S307
R
K
I
K
N
K
I
S
A
Q
E
S
R
R
K
Site 49
S311
N
K
I
S
A
Q
E
S
R
R
K
K
K
E
Y
Site 50
Y318
S
R
R
K
K
K
E
Y
M
D
S
L
E
K
K
Site 51
S321
K
K
K
E
Y
M
D
S
L
E
K
K
V
E
S
Site 52
T331
K
K
V
E
S
C
S
T
E
N
L
E
L
R
K
Site 53
T346
K
V
E
V
L
E
N
T
N
R
T
L
L
Q
Q
Site 54
T359
Q
Q
L
Q
K
L
Q
T
L
V
M
G
K
V
S
Site 55
Y398
F
G
S
F
F
Q
G
Y
G
P
Y
P
S
A
T
Site 56
Y401
F
F
Q
G
Y
G
P
Y
P
S
A
T
K
M
A
Site 57
S403
Q
G
Y
G
P
Y
P
S
A
T
K
M
A
L
P
Site 58
T405
Y
G
P
Y
P
S
A
T
K
M
A
L
P
S
Q
Site 59
S411
A
T
K
M
A
L
P
S
Q
H
S
L
Q
E
P
Site 60
S414
M
A
L
P
S
Q
H
S
L
Q
E
P
Y
T
A
Site 61
T420
H
S
L
Q
E
P
Y
T
A
S
V
V
R
S
R
Site 62
S422
L
Q
E
P
Y
T
A
S
V
V
R
S
R
N
L
Site 63
S426
Y
T
A
S
V
V
R
S
R
N
L
L
I
Y
E
Site 64
Y432
R
S
R
N
L
L
I
Y
E
E
H
S
P
P
E
Site 65
S436
L
L
I
Y
E
E
H
S
P
P
E
E
S
S
S
Site 66
S441
E
H
S
P
P
E
E
S
S
S
P
G
S
A
G
Site 67
S442
H
S
P
P
E
E
S
S
S
P
G
S
A
G
E
Site 68
S443
S
P
P
E
E
S
S
S
P
G
S
A
G
E
L
Site 69
S446
E
E
S
S
S
P
G
S
A
G
E
L
G
G
W
Site 70
S457
L
G
G
W
D
R
G
S
S
L
L
R
V
S
G
Site 71
S458
G
G
W
D
R
G
S
S
L
L
R
V
S
G
L
Site 72
S463
G
S
S
L
L
R
V
S
G
L
E
S
R
P
D
Site 73
S467
L
R
V
S
G
L
E
S
R
P
D
V
D
L
P
Site 74
S479
D
L
P
H
F
I
I
S
N
E
T
S
L
E
K
Site 75
S487
N
E
T
S
L
E
K
S
V
L
L
E
L
Q
Q
Site 76
T506
A
K
L
E
G
N
E
T
L
K
V
V
E
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation