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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BBS12
Full Name:
Bardet-Biedl syndrome 12 protein
Alias:
Type:
Mass (Da):
79085
Number AA:
710
UniProt ID:
Q6ZW61
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
H
M
G
L
Q
Q
L
S
S
F
A
E
T
G
R
Site 2
S21
M
G
L
Q
Q
L
S
S
F
A
E
T
G
R
T
Site 3
T25
Q
L
S
S
F
A
E
T
G
R
T
F
L
G
P
Site 4
T28
S
F
A
E
T
G
R
T
F
L
G
P
L
K
S
Site 5
S124
S
E
G
L
N
F
C
S
E
E
V
V
S
L
H
Site 6
T144
I
F
D
C
M
D
S
T
K
T
F
S
Q
L
E
Site 7
T146
D
C
M
D
S
T
K
T
F
S
Q
L
E
T
F
Site 8
S148
M
D
S
T
K
T
F
S
Q
L
E
T
F
S
V
Site 9
S181
H
G
L
K
D
V
A
S
Q
T
L
T
I
S
N
Site 10
T185
D
V
A
S
Q
T
L
T
I
S
N
L
S
G
R
Site 11
S190
T
L
T
I
S
N
L
S
G
R
P
L
K
S
Y
Site 12
S196
L
S
G
R
P
L
K
S
Y
E
L
F
K
P
Q
Site 13
Y197
S
G
R
P
L
K
S
Y
E
L
F
K
P
Q
T
Site 14
T212
K
V
E
A
D
N
N
T
S
R
T
L
K
N
S
Site 15
T215
A
D
N
N
T
S
R
T
L
K
N
S
L
L
A
Site 16
S219
T
S
R
T
L
K
N
S
L
L
A
D
T
C
C
Site 17
T224
K
N
S
L
L
A
D
T
C
C
R
Q
S
I
L
Site 18
T240
H
S
R
H
F
N
R
T
D
N
T
E
G
V
S
Site 19
T243
H
F
N
R
T
D
N
T
E
G
V
S
K
P
D
Site 20
T257
D
G
F
Q
E
H
V
T
A
T
H
K
T
Y
R
Site 21
S281
G
L
S
H
G
D
H
S
S
M
K
L
V
E
E
Site 22
S282
L
S
H
G
D
H
S
S
M
K
L
V
E
E
A
Site 23
T364
V
L
I
E
G
D
L
T
E
N
Y
R
H
L
G
Site 24
Y367
E
G
D
L
T
E
N
Y
R
H
L
G
F
N
K
Site 25
S375
R
H
L
G
F
N
K
S
A
N
I
K
T
V
L
Site 26
T380
N
K
S
A
N
I
K
T
V
L
D
S
M
Q
L
Site 27
S384
N
I
K
T
V
L
D
S
M
Q
L
Q
E
D
S
Site 28
S391
S
M
Q
L
Q
E
D
S
S
E
E
L
W
A
N
Site 29
S392
M
Q
L
Q
E
D
S
S
E
E
L
W
A
N
H
Site 30
S477
C
V
T
F
W
R
S
S
P
L
D
V
V
D
R
Site 31
T501
T
E
G
I
N
L
V
T
A
V
L
T
N
P
V
Site 32
Y527
W
T
C
A
Y
R
L
Y
Y
A
L
K
E
E
K
Site 33
Y528
T
C
A
Y
R
L
Y
Y
A
L
K
E
E
K
V
Site 34
S557
L
H
I
L
A
E
Q
S
L
K
K
E
N
H
A
Site 35
S573
S
G
W
L
H
N
T
S
S
W
L
A
S
S
L
Site 36
S574
G
W
L
H
N
T
S
S
W
L
A
S
S
L
A
Site 37
S578
N
T
S
S
W
L
A
S
S
L
A
I
Y
R
P
Site 38
S579
T
S
S
W
L
A
S
S
L
A
I
Y
R
P
T
Site 39
Y598
L
A
N
G
W
Q
K
Y
L
S
T
L
L
Y
N
Site 40
Y604
K
Y
L
S
T
L
L
Y
N
T
A
N
Y
S
S
Site 41
T606
L
S
T
L
L
Y
N
T
A
N
Y
S
S
E
F
Site 42
S616
Y
S
S
E
F
E
A
S
T
Y
I
Q
H
H
L
Site 43
Y618
S
E
F
E
A
S
T
Y
I
Q
H
H
L
Q
N
Site 44
T627
Q
H
H
L
Q
N
A
T
D
S
G
S
P
S
S
Site 45
S629
H
L
Q
N
A
T
D
S
G
S
P
S
S
Y
I
Site 46
S631
Q
N
A
T
D
S
G
S
P
S
S
Y
I
L
N
Site 47
S633
A
T
D
S
G
S
P
S
S
Y
I
L
N
E
Y
Site 48
S634
T
D
S
G
S
P
S
S
Y
I
L
N
E
Y
S
Site 49
Y635
D
S
G
S
P
S
S
Y
I
L
N
E
Y
S
K
Site 50
S641
S
Y
I
L
N
E
Y
S
K
L
N
S
R
I
F
Site 51
S645
N
E
Y
S
K
L
N
S
R
I
F
N
S
D
I
Site 52
S650
L
N
S
R
I
F
N
S
D
I
S
N
K
L
E
Site 53
T667
P
R
V
Y
D
V
V
T
P
K
I
E
A
W
R
Site 54
T692
Q
T
D
S
E
I
I
T
G
H
G
H
T
Q
I
Site 55
S701
H
G
H
T
Q
I
N
S
Q
E
L
T
G
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation