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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C14orf145
Full Name:
Uncharacterized protein C14orf145
Alias:
CN145; Uncharacterized protein C14orf145
Type:
Uncharacterized
Mass (Da):
128015
Number AA:
1094
UniProt ID:
Q6ZU80
International Prot ID:
IPI00719446
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
E
S
S
S
E
S
D
H
F
R
C
R
D
Site 2
S18
F
R
C
R
D
R
L
S
P
W
A
A
R
S
T
Site 3
S24
L
S
P
W
A
A
R
S
T
H
R
G
T
R
S
Site 4
T25
S
P
W
A
A
R
S
T
H
R
G
T
R
S
L
Site 5
T29
A
R
S
T
H
R
G
T
R
S
L
P
T
V
E
Site 6
S31
S
T
H
R
G
T
R
S
L
P
T
V
E
V
T
Site 7
T34
R
G
T
R
S
L
P
T
V
E
V
T
E
K
V
Site 8
T43
E
V
T
E
K
V
N
T
I
T
S
T
L
Q
D
Site 9
T47
K
V
N
T
I
T
S
T
L
Q
D
T
S
R
N
Site 10
T51
I
T
S
T
L
Q
D
T
S
R
N
L
R
Q
V
Site 11
Y65
V
D
Q
M
L
G
R
Y
R
E
Y
S
N
G
Q
Site 12
Y68
M
L
G
R
Y
R
E
Y
S
N
G
Q
A
G
A
Site 13
S69
L
G
R
Y
R
E
Y
S
N
G
Q
A
G
A
I
Site 14
S82
A
I
E
H
L
K
E
S
L
E
Q
S
I
D
Q
Site 15
S86
L
K
E
S
L
E
Q
S
I
D
Q
L
R
S
Q
Site 16
S92
Q
S
I
D
Q
L
R
S
Q
R
L
L
R
N
S
Site 17
S99
S
Q
R
L
L
R
N
S
G
G
R
S
I
S
V
Site 18
S103
L
R
N
S
G
G
R
S
I
S
V
T
S
L
S
Site 19
S105
N
S
G
G
R
S
I
S
V
T
S
L
S
A
S
Site 20
T107
G
G
R
S
I
S
V
T
S
L
S
A
S
D
L
Site 21
S108
G
R
S
I
S
V
T
S
L
S
A
S
D
L
D
Site 22
S110
S
I
S
V
T
S
L
S
A
S
D
L
D
G
G
Site 23
S112
S
V
T
S
L
S
A
S
D
L
D
G
G
T
G
Site 24
T118
A
S
D
L
D
G
G
T
G
S
E
L
H
H
F
Site 25
S120
D
L
D
G
G
T
G
S
E
L
H
H
F
P
P
Site 26
S129
L
H
H
F
P
P
T
S
P
L
K
D
Y
G
D
Site 27
Y134
P
T
S
P
L
K
D
Y
G
D
P
Q
G
I
K
Site 28
S145
Q
G
I
K
R
M
R
S
R
T
G
V
R
F
V
Site 29
T147
I
K
R
M
R
S
R
T
G
V
R
F
V
Q
E
Site 30
T155
G
V
R
F
V
Q
E
T
D
D
M
T
Q
L
H
Site 31
S167
Q
L
H
G
F
H
Q
S
L
R
D
L
S
S
E
Site 32
S172
H
Q
S
L
R
D
L
S
S
E
Q
I
R
L
G
Site 33
S173
Q
S
L
R
D
L
S
S
E
Q
I
R
L
G
D
Site 34
S187
D
D
F
N
R
E
L
S
R
R
S
R
S
D
A
Site 35
S190
N
R
E
L
S
R
R
S
R
S
D
A
E
T
K
Site 36
S192
E
L
S
R
R
S
R
S
D
A
E
T
K
R
A
Site 37
T196
R
S
R
S
D
A
E
T
K
R
A
L
E
E
L
Site 38
S217
A
Q
K
Q
E
V
V
S
D
R
V
E
R
R
L
Site 39
S249
Q
D
Q
L
G
L
M
S
L
Q
L
Q
E
A
L
Site 40
T277
I
K
N
K
L
R
Q
T
E
T
E
K
N
Q
L
Site 41
S291
L
E
Q
E
L
E
L
S
R
R
L
L
N
Q
S
Site 42
S298
S
R
R
L
L
N
Q
S
E
G
S
R
E
T
L
Site 43
T304
Q
S
E
G
S
R
E
T
L
L
H
Q
V
E
E
Site 44
S331
K
G
L
Q
H
Q
V
S
Q
I
S
K
Q
Q
S
Site 45
S334
Q
H
Q
V
S
Q
I
S
K
Q
Q
S
N
Y
Q
Site 46
S338
S
Q
I
S
K
Q
Q
S
N
Y
Q
D
E
Q
G
Site 47
Y340
I
S
K
Q
Q
S
N
Y
Q
D
E
Q
G
E
D
Site 48
S366
Q
D
L
E
K
Q
M
S
D
L
R
V
Q
L
N
Site 49
S379
L
N
F
S
A
M
A
S
E
L
E
E
V
K
R
Site 50
S400
K
E
K
A
H
L
A
S
Q
V
E
N
L
T
R
Site 51
T432
E
I
Q
N
H
F
D
T
C
E
A
E
R
K
H
Site 52
Y461
A
T
K
Q
A
E
R
Y
L
S
E
L
Q
Q
S
Site 53
S463
K
Q
A
E
R
Y
L
S
E
L
Q
Q
S
E
A
Site 54
S468
Y
L
S
E
L
Q
Q
S
E
A
L
K
E
E
A
Site 55
S489
L
K
L
K
A
Q
E
S
I
R
Q
W
K
L
K
Site 56
T510
A
L
E
K
Q
S
E
T
V
D
E
L
T
G
K
Site 57
T515
S
E
T
V
D
E
L
T
G
K
N
N
Q
I
L
Site 58
Y533
D
E
L
K
T
Q
L
Y
A
A
L
Q
Q
I
E
Site 59
T551
K
E
L
N
D
V
L
T
K
R
A
L
Q
E
E
Site 60
S562
L
Q
E
E
E
L
H
S
K
E
E
K
L
R
D
Site 61
S572
E
K
L
R
D
I
K
S
H
Q
A
D
L
E
L
Site 62
S584
L
E
L
E
V
K
N
S
L
D
T
I
H
R
L
Site 63
T587
E
V
K
N
S
L
D
T
I
H
R
L
E
S
E
Site 64
S593
D
T
I
H
R
L
E
S
E
L
K
K
Q
S
K
Site 65
S599
E
S
E
L
K
K
Q
S
K
I
Q
S
Q
M
K
Site 66
S603
K
K
Q
S
K
I
Q
S
Q
M
K
V
E
K
A
Site 67
S622
E
I
A
E
L
K
K
S
Q
A
Q
D
K
A
K
Site 68
S636
K
L
L
E
M
Q
E
S
I
K
D
L
S
A
I
Site 69
S666
K
A
V
L
K
D
L
S
D
L
T
A
Q
A
K
Site 70
T669
L
K
D
L
S
D
L
T
A
Q
A
K
S
R
D
Site 71
T681
S
R
D
E
E
T
A
T
I
I
T
Q
L
K
L
Site 72
T701
Q
R
E
L
K
D
L
T
S
S
L
Q
S
V
K
Site 73
S702
R
E
L
K
D
L
T
S
S
L
Q
S
V
K
T
Site 74
S703
E
L
K
D
L
T
S
S
L
Q
S
V
K
T
K
Site 75
S706
D
L
T
S
S
L
Q
S
V
K
T
K
H
E
Q
Site 76
T709
S
S
L
Q
S
V
K
T
K
H
E
Q
N
I
Q
Site 77
S727
K
H
F
K
K
E
K
S
E
A
E
N
H
I
R
Site 78
S740
I
R
T
L
K
A
E
S
L
E
E
K
N
M
A
Site 79
S759
G
Q
L
E
K
L
K
S
Q
C
D
R
L
T
E
Site 80
T765
K
S
Q
C
D
R
L
T
E
E
L
T
Q
N
E
Site 81
Y782
N
K
K
L
K
L
K
Y
Q
C
L
K
D
Q
L
Site 82
S797
E
E
R
E
K
H
I
S
I
E
E
E
H
L
R
Site 83
T822
D
Q
L
L
C
L
E
T
E
Q
E
S
I
L
G
Site 84
T841
E
I
D
A
A
C
K
T
F
S
K
D
S
V
E
Site 85
S843
D
A
A
C
K
T
F
S
K
D
S
V
E
K
L
Site 86
S846
C
K
T
F
S
K
D
S
V
E
K
L
K
V
F
Site 87
S855
E
K
L
K
V
F
S
S
G
P
D
I
H
Y
D
Site 88
Y861
S
S
G
P
D
I
H
Y
D
P
H
R
W
L
A
Site 89
T872
R
W
L
A
E
S
K
T
K
L
Q
W
L
C
E
Site 90
T906
R
Q
Q
L
R
N
L
T
E
N
K
E
S
E
L
Site 91
S911
N
L
T
E
N
K
E
S
E
L
Q
C
L
F
Q
Site 92
T941
K
R
D
L
L
E
E
T
Q
R
K
D
E
E
M
Site 93
S950
R
K
D
E
E
M
G
S
L
Q
D
R
V
I
A
Site 94
S977
E
S
V
P
E
K
L
S
L
L
E
D
F
K
D
Site 95
S988
D
F
K
D
F
R
D
S
C
S
S
S
E
R
T
Site 96
S990
K
D
F
R
D
S
C
S
S
S
E
R
T
D
G
Site 97
S991
D
F
R
D
S
C
S
S
S
E
R
T
D
G
R
Site 98
S992
F
R
D
S
C
S
S
S
E
R
T
D
G
R
Y
Site 99
T995
S
C
S
S
S
E
R
T
D
G
R
Y
S
K
Y
Site 100
Y999
S
E
R
T
D
G
R
Y
S
K
Y
R
V
R
R
Site 101
S1000
E
R
T
D
G
R
Y
S
K
Y
R
V
R
R
N
Site 102
Y1002
T
D
G
R
Y
S
K
Y
R
V
R
R
N
S
L
Site 103
S1008
K
Y
R
V
R
R
N
S
L
Q
H
H
Q
D
D
Site 104
T1016
L
Q
H
H
Q
D
D
T
K
Y
R
T
K
S
F
Site 105
Y1018
H
H
Q
D
D
T
K
Y
R
T
K
S
F
K
G
Site 106
S1022
D
T
K
Y
R
T
K
S
F
K
G
D
R
T
F
Site 107
T1028
K
S
F
K
G
D
R
T
F
L
E
G
S
H
T
Site 108
S1033
D
R
T
F
L
E
G
S
H
T
R
G
L
D
H
Site 109
T1035
T
F
L
E
G
S
H
T
R
G
L
D
H
S
S
Site 110
S1041
H
T
R
G
L
D
H
S
S
S
W
Q
D
H
S
Site 111
S1042
T
R
G
L
D
H
S
S
S
W
Q
D
H
S
R
Site 112
S1043
R
G
L
D
H
S
S
S
W
Q
D
H
S
R
F
Site 113
S1048
S
S
S
W
Q
D
H
S
R
F
L
S
S
P
R
Site 114
S1052
Q
D
H
S
R
F
L
S
S
P
R
F
S
Y
V
Site 115
S1053
D
H
S
R
F
L
S
S
P
R
F
S
Y
V
N
Site 116
S1057
F
L
S
S
P
R
F
S
Y
V
N
S
F
T
K
Site 117
Y1058
L
S
S
P
R
F
S
Y
V
N
S
F
T
K
R
Site 118
S1061
P
R
F
S
Y
V
N
S
F
T
K
R
T
V
A
Site 119
T1066
V
N
S
F
T
K
R
T
V
A
P
D
S
A
S
Site 120
S1071
K
R
T
V
A
P
D
S
A
S
N
K
E
D
A
Site 121
S1073
T
V
A
P
D
S
A
S
N
K
E
D
A
T
M
Site 122
T1079
A
S
N
K
E
D
A
T
M
N
G
T
S
S
Q
Site 123
S1085
A
T
M
N
G
T
S
S
Q
P
K
K
E
E
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation