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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C9orf144B
Full Name:
Transmembrane protein C9orf144B
Alias:
Type:
Mass (Da):
148096
Number AA:
1335
UniProt ID:
Q6ZU69
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
I
I
W
Q
V
K
R
S
H
H
E
L
S
S
E
Site 2
S39
K
R
S
H
H
E
L
S
S
E
P
K
R
S
C
Site 3
S40
R
S
H
H
E
L
S
S
E
P
K
R
S
C
C
Site 4
S45
L
S
S
E
P
K
R
S
C
C
R
C
H
Q
K
Site 5
S62
Q
R
A
R
D
A
A
S
T
A
R
R
R
S
R
Site 6
T63
R
A
R
D
A
A
S
T
A
R
R
R
S
R
E
Site 7
S68
A
S
T
A
R
R
R
S
R
E
E
A
E
K
P
Site 8
S80
E
K
P
Q
K
L
L
S
I
I
K
S
Q
G
W
Site 9
S126
V
G
E
N
N
Q
I
S
L
T
L
S
G
P
L
Site 10
T128
E
N
N
Q
I
S
L
T
L
S
G
P
L
Q
G
Site 11
S130
N
Q
I
S
L
T
L
S
G
P
L
Q
G
S
S
Site 12
S137
S
G
P
L
Q
G
S
S
C
L
E
M
L
S
T
Site 13
S143
S
S
C
L
E
M
L
S
T
S
S
M
S
L
D
Site 14
T144
S
C
L
E
M
L
S
T
S
S
M
S
L
D
Q
Site 15
S146
L
E
M
L
S
T
S
S
M
S
L
D
Q
S
L
Site 16
S148
M
L
S
T
S
S
M
S
L
D
Q
S
L
E
F
Site 17
S152
S
S
M
S
L
D
Q
S
L
E
F
H
S
W
H
Site 18
S164
S
W
H
T
R
E
L
S
L
S
S
V
T
P
T
Site 19
S166
H
T
R
E
L
S
L
S
S
V
T
P
T
L
S
Site 20
S167
T
R
E
L
S
L
S
S
V
T
P
T
L
S
Q
Site 21
T171
S
L
S
S
V
T
P
T
L
S
Q
L
T
D
Q
Site 22
S173
S
S
V
T
P
T
L
S
Q
L
T
D
Q
K
S
Site 23
S180
S
Q
L
T
D
Q
K
S
L
T
Q
S
A
A
Q
Site 24
T182
L
T
D
Q
K
S
L
T
Q
S
A
A
Q
S
T
Site 25
S184
D
Q
K
S
L
T
Q
S
A
A
Q
S
T
Y
A
Site 26
S188
L
T
Q
S
A
A
Q
S
T
Y
A
D
G
I
Q
Site 27
Y197
Y
A
D
G
I
Q
D
Y
W
A
D
H
L
Q
L
Site 28
T219
D
V
L
R
G
P
N
T
I
A
S
S
R
I
E
Site 29
S222
R
G
P
N
T
I
A
S
S
R
I
E
K
P
R
Site 30
S240
N
Q
E
E
M
T
Q
S
N
P
S
L
V
Q
G
Site 31
S243
E
M
T
Q
S
N
P
S
L
V
Q
G
N
Q
G
Site 32
S256
Q
G
Q
H
H
L
N
S
Q
V
S
L
L
S
L
Site 33
S259
H
H
L
N
S
Q
V
S
L
L
S
L
N
P
E
Site 34
S262
N
S
Q
V
S
L
L
S
L
N
P
E
T
L
N
Site 35
T267
L
L
S
L
N
P
E
T
L
N
R
M
H
P
M
Site 36
S317
L
P
R
R
V
E
E
S
L
R
Q
L
M
P
N
Site 37
Y328
L
M
P
N
P
P
L
Y
Y
Q
P
G
N
D
Q
Site 38
S338
P
G
N
D
Q
P
V
S
F
N
L
K
N
T
P
Site 39
T344
V
S
F
N
L
K
N
T
P
Q
V
S
L
H
R
Site 40
S348
L
K
N
T
P
Q
V
S
L
H
R
F
E
T
I
Site 41
T371
V
A
G
Q
P
I
Q
T
F
W
V
S
E
W
S
Site 42
T391
Q
R
H
H
C
Q
Q
T
P
N
P
M
A
L
A
Site 43
S408
S
P
A
L
K
A
L
S
G
P
H
P
Q
S
G
Site 44
S414
L
S
G
P
H
P
Q
S
G
G
Q
D
N
D
S
Site 45
S421
S
G
G
Q
D
N
D
S
G
S
D
L
Q
Q
K
Site 46
S423
G
Q
D
N
D
S
G
S
D
L
Q
Q
K
Y
S
Site 47
Y429
G
S
D
L
Q
Q
K
Y
S
Q
L
F
C
G
L
Site 48
S430
S
D
L
Q
Q
K
Y
S
Q
L
F
C
G
L
P
Site 49
T483
F
P
Q
L
L
P
K
T
S
P
Q
S
A
P
P
Site 50
S484
P
Q
L
L
P
K
T
S
P
Q
S
A
P
P
S
Site 51
S487
L
P
K
T
S
P
Q
S
A
P
P
S
S
P
L
Site 52
S491
S
P
Q
S
A
P
P
S
S
P
L
S
P
N
W
Site 53
S492
P
Q
S
A
P
P
S
S
P
L
S
P
N
W
M
Site 54
S495
A
P
P
S
S
P
L
S
P
N
W
M
S
P
S
Site 55
S500
P
L
S
P
N
W
M
S
P
S
D
H
Q
R
A
Site 56
S502
S
P
N
W
M
S
P
S
D
H
Q
R
A
Q
I
Site 57
S561
E
P
C
G
K
A
Q
S
P
E
T
T
T
A
S
Site 58
T564
G
K
A
Q
S
P
E
T
T
T
A
S
Q
T
G
Site 59
T565
K
A
Q
S
P
E
T
T
T
A
S
Q
T
G
K
Site 60
S568
S
P
E
T
T
T
A
S
Q
T
G
K
S
I
S
Site 61
S573
T
A
S
Q
T
G
K
S
I
S
V
L
T
R
E
Site 62
S575
S
Q
T
G
K
S
I
S
V
L
T
R
E
L
L
Site 63
T626
L
T
S
T
D
Q
Q
T
V
S
S
S
S
T
A
Site 64
S628
S
T
D
Q
Q
T
V
S
S
S
S
T
A
L
A
Site 65
S678
Q
V
K
A
I
L
Q
S
H
I
D
S
K
C
G
Site 66
S719
P
F
P
C
I
P
E
S
Q
F
L
E
L
Q
T
Site 67
T754
Q
Q
Q
A
L
P
G
T
V
T
E
H
P
K
L
Site 68
T756
Q
A
L
P
G
T
V
T
E
H
P
K
L
L
R
Site 69
T775
E
A
I
E
K
L
E
T
T
L
R
H
K
H
L
Site 70
T776
A
I
E
K
L
E
T
T
L
R
H
K
H
L
A
Site 71
S816
V
I
T
E
M
E
P
S
P
V
E
I
P
A
E
Site 72
S837
S
F
E
E
Q
C
I
S
L
G
P
C
P
Q
G
Site 73
T875
T
L
P
L
E
S
Q
T
H
P
T
S
P
H
S
Site 74
T878
L
E
S
Q
T
H
P
T
S
P
H
S
L
Q
T
Site 75
S879
E
S
Q
T
H
P
T
S
P
H
S
L
Q
T
H
Site 76
S882
T
H
P
T
S
P
H
S
L
Q
T
H
I
L
T
Site 77
T889
S
L
Q
T
H
I
L
T
K
L
N
F
H
L
R
Site 78
S913
I
P
I
R
A
R
K
S
R
E
Q
T
V
A
A
Site 79
T917
A
R
K
S
R
E
Q
T
V
A
A
P
E
N
I
Site 80
S925
V
A
A
P
E
N
I
S
T
Q
K
S
L
E
S
Site 81
T926
A
A
P
E
N
I
S
T
Q
K
S
L
E
S
L
Site 82
S929
E
N
I
S
T
Q
K
S
L
E
S
L
N
H
Q
Site 83
S932
S
T
Q
K
S
L
E
S
L
N
H
Q
G
E
T
Site 84
T950
E
L
P
I
P
P
D
T
L
P
A
P
N
P
E
Site 85
S988
S
K
A
V
P
Q
G
S
A
H
S
V
S
K
I
Site 86
S991
V
P
Q
G
S
A
H
S
V
S
K
I
S
Q
P
Site 87
S993
Q
G
S
A
H
S
V
S
K
I
S
Q
P
S
G
Site 88
S996
A
H
S
V
S
K
I
S
Q
P
S
G
D
M
T
Site 89
T1003
S
Q
P
S
G
D
M
T
E
A
H
M
P
C
V
Site 90
S1020
E
A
N
V
N
K
P
S
L
E
E
P
C
G
P
Site 91
S1031
P
C
G
P
E
P
Q
S
P
S
K
S
K
D
P
Site 92
S1033
G
P
E
P
Q
S
P
S
K
S
K
D
P
A
H
Site 93
S1035
E
P
Q
S
P
S
K
S
K
D
P
A
H
V
P
Site 94
S1070
G
D
A
G
F
G
R
S
S
T
R
E
E
R
R
Site 95
S1071
D
A
G
F
G
R
S
S
T
R
E
E
R
R
P
Site 96
T1072
A
G
F
G
R
S
S
T
R
E
E
R
R
P
A
Site 97
T1092
A
G
M
L
P
N
K
T
P
R
G
S
W
R
W
Site 98
S1096
P
N
K
T
P
R
G
S
W
R
W
S
R
S
F
Site 99
S1100
P
R
G
S
W
R
W
S
R
S
F
H
L
A
D
Site 100
S1112
L
A
D
P
C
Q
H
S
P
Q
H
H
P
Q
L
Site 101
S1141
S
E
K
D
L
Q
D
S
Q
T
K
L
T
V
I
Site 102
T1146
Q
D
S
Q
T
K
L
T
V
I
L
E
P
A
T
Site 103
T1160
T
I
P
E
N
A
Q
T
V
L
P
Q
A
S
Q
Site 104
S1173
S
Q
G
Q
P
F
L
S
Q
P
T
Q
A
K
P
Site 105
S1205
V
H
A
Q
K
K
P
S
L
T
E
S
S
F
R
Site 106
T1207
A
Q
K
K
P
S
L
T
E
S
S
F
R
N
K
Site 107
S1209
K
K
P
S
L
T
E
S
S
F
R
N
K
I
K
Site 108
S1210
K
P
S
L
T
E
S
S
F
R
N
K
I
K
C
Site 109
T1226
L
Q
H
I
N
P
K
T
K
G
K
G
H
E
D
Site 110
S1234
K
G
K
G
H
E
D
S
M
F
S
A
A
A
K
Site 111
S1253
R
K
E
N
V
A
K
S
L
A
P
A
K
S
P
Site 112
S1259
K
S
L
A
P
A
K
S
P
V
G
R
S
K
T
Site 113
S1264
A
K
S
P
V
G
R
S
K
T
E
K
P
T
G
Site 114
T1266
S
P
V
G
R
S
K
T
E
K
P
T
G
C
S
Site 115
S1273
T
E
K
P
T
G
C
S
K
A
Q
S
R
P
A
Site 116
S1277
T
G
C
S
K
A
Q
S
R
P
A
Q
K
L
V
Site 117
S1294
A
F
L
D
G
P
Q
S
L
D
D
K
L
R
L
Site 118
S1303
D
D
K
L
R
L
H
S
R
Q
P
G
S
A
S
Site 119
S1308
L
H
S
R
Q
P
G
S
A
S
A
L
G
Y
P
Site 120
S1310
S
R
Q
P
G
S
A
S
A
L
G
Y
P
R
H
Site 121
Y1314
G
S
A
S
A
L
G
Y
P
R
H
C
P
R
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation