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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTLL7
Full Name:
Tubulin polyglutamylase TTLL7
Alias:
Testis development protein NYD-SP30;Tubulin--tyrosine ligase-like protein 7
Type:
Mass (Da):
102999
Number AA:
887
UniProt ID:
Q6ZT98
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
G
V
I
Q
G
P
S
P
L
D
L
N
T
E
Site 2
T20
P
S
P
L
D
L
N
T
E
L
P
Y
Q
S
T
Site 3
T27
T
E
L
P
Y
Q
S
T
M
K
R
K
V
R
K
Site 4
T65
D
E
M
G
F
M
K
T
P
D
E
D
E
T
S
Site 5
Y92
K
I
S
E
L
Q
N
Y
Q
R
I
N
H
F
P
Site 6
T115
D
F
L
A
R
N
M
T
K
M
I
K
S
R
P
Site 7
Y125
I
K
S
R
P
L
D
Y
T
F
V
P
R
T
W
Site 8
T126
K
S
R
P
L
D
Y
T
F
V
P
R
T
W
I
Site 9
Y144
E
Y
T
Q
F
Q
N
Y
V
K
E
L
K
K
K
Site 10
T156
K
K
K
R
K
Q
K
T
F
I
V
K
P
A
N
Site 11
S171
G
A
M
G
H
G
I
S
L
I
R
N
G
D
K
Site 12
S181
R
N
G
D
K
L
P
S
Q
D
H
L
I
V
Q
Site 13
T230
D
G
L
V
R
M
G
T
E
K
Y
I
P
P
N
Site 14
Y233
V
R
M
G
T
E
K
Y
I
P
P
N
E
S
N
Site 15
T242
P
P
N
E
S
N
L
T
Q
L
Y
M
H
L
T
Site 16
Y245
E
S
N
L
T
Q
L
Y
M
H
L
T
N
Y
S
Site 17
Y251
L
Y
M
H
L
T
N
Y
S
V
N
K
H
N
E
Site 18
T265
E
H
F
E
R
D
E
T
E
N
K
G
S
K
R
Site 19
S270
D
E
T
E
N
K
G
S
K
R
S
I
K
W
F
Site 20
S273
E
N
K
G
S
K
R
S
I
K
W
F
T
E
F
Site 21
T278
K
R
S
I
K
W
F
T
E
F
L
Q
A
N
Q
Site 22
Y314
E
P
H
V
L
H
A
Y
R
M
C
R
P
G
Q
Site 23
S325
R
P
G
Q
P
P
G
S
E
S
V
C
F
E
V
Site 24
S327
G
Q
P
P
G
S
E
S
V
C
F
E
V
L
G
Site 25
S355
L
E
I
N
R
A
P
S
F
G
T
D
Q
K
I
Site 26
Y364
G
T
D
Q
K
I
D
Y
D
V
K
R
G
V
L
Site 27
S383
K
L
L
N
I
R
T
S
D
K
R
R
N
L
A
Site 28
Y401
A
E
A
Q
R
R
L
Y
G
Q
N
S
I
K
R
Site 29
S405
R
R
L
Y
G
Q
N
S
I
K
R
L
L
P
G
Site 30
S413
I
K
R
L
L
P
G
S
S
D
W
E
Q
Q
R
Site 31
S414
K
R
L
L
P
G
S
S
D
W
E
Q
Q
R
H
Site 32
Y454
E
N
R
H
M
G
N
Y
R
R
I
Y
P
P
E
Site 33
Y458
M
G
N
Y
R
R
I
Y
P
P
E
D
K
A
L
Site 34
S487
F
L
S
G
R
A
A
S
F
Q
R
E
L
N
N
Site 35
T523
E
K
L
M
G
K
T
T
K
T
R
G
P
K
P
Site 36
T525
L
M
G
K
T
T
K
T
R
G
P
K
P
L
C
Site 37
S533
R
G
P
K
P
L
C
S
M
P
E
S
T
E
I
Site 38
S537
P
L
C
S
M
P
E
S
T
E
I
M
K
R
P
Site 39
Y546
E
I
M
K
R
P
K
Y
C
S
S
D
S
S
Y
Site 40
S548
M
K
R
P
K
Y
C
S
S
D
S
S
Y
D
S
Site 41
S549
K
R
P
K
Y
C
S
S
D
S
S
Y
D
S
S
Site 42
S551
P
K
Y
C
S
S
D
S
S
Y
D
S
S
S
S
Site 43
S552
K
Y
C
S
S
D
S
S
Y
D
S
S
S
S
S
Site 44
Y553
Y
C
S
S
D
S
S
Y
D
S
S
S
S
S
S
Site 45
S555
S
S
D
S
S
Y
D
S
S
S
S
S
S
E
S
Site 46
S556
S
D
S
S
Y
D
S
S
S
S
S
S
E
S
D
Site 47
S557
D
S
S
Y
D
S
S
S
S
S
S
E
S
D
E
Site 48
S558
S
S
Y
D
S
S
S
S
S
S
E
S
D
E
N
Site 49
S559
S
Y
D
S
S
S
S
S
S
E
S
D
E
N
E
Site 50
S560
Y
D
S
S
S
S
S
S
E
S
D
E
N
E
K
Site 51
S562
S
S
S
S
S
S
E
S
D
E
N
E
K
E
E
Site 52
Y570
D
E
N
E
K
E
E
Y
Q
N
K
K
R
E
K
Site 53
T580
K
K
R
E
K
Q
V
T
Y
N
L
K
P
S
N
Site 54
Y581
K
R
E
K
Q
V
T
Y
N
L
K
P
S
N
H
Site 55
S586
V
T
Y
N
L
K
P
S
N
H
Y
K
L
I
Q
Site 56
S596
Y
K
L
I
Q
Q
P
S
S
I
R
R
S
V
S
Site 57
S597
K
L
I
Q
Q
P
S
S
I
R
R
S
V
S
C
Site 58
S601
Q
P
S
S
I
R
R
S
V
S
C
P
R
S
I
Site 59
S603
S
S
I
R
R
S
V
S
C
P
R
S
I
S
A
Site 60
S607
R
S
V
S
C
P
R
S
I
S
A
Q
S
P
S
Site 61
S609
V
S
C
P
R
S
I
S
A
Q
S
P
S
S
G
Site 62
S612
P
R
S
I
S
A
Q
S
P
S
S
G
D
T
R
Site 63
S614
S
I
S
A
Q
S
P
S
S
G
D
T
R
P
F
Site 64
S615
I
S
A
Q
S
P
S
S
G
D
T
R
P
F
S
Site 65
T618
Q
S
P
S
S
G
D
T
R
P
F
S
A
Q
Q
Site 66
S622
S
G
D
T
R
P
F
S
A
Q
Q
M
I
S
V
Site 67
S628
F
S
A
Q
Q
M
I
S
V
S
R
P
T
S
A
Site 68
S630
A
Q
Q
M
I
S
V
S
R
P
T
S
A
S
R
Site 69
T633
M
I
S
V
S
R
P
T
S
A
S
R
S
H
S
Site 70
S634
I
S
V
S
R
P
T
S
A
S
R
S
H
S
L
Site 71
S636
V
S
R
P
T
S
A
S
R
S
H
S
L
N
R
Site 72
S638
R
P
T
S
A
S
R
S
H
S
L
N
R
A
S
Site 73
S640
T
S
A
S
R
S
H
S
L
N
R
A
S
S
Y
Site 74
S645
S
H
S
L
N
R
A
S
S
Y
M
R
H
L
P
Site 75
S646
H
S
L
N
R
A
S
S
Y
M
R
H
L
P
H
Site 76
Y647
S
L
N
R
A
S
S
Y
M
R
H
L
P
H
S
Site 77
S659
P
H
S
N
D
A
C
S
T
N
S
Q
V
S
E
Site 78
S662
N
D
A
C
S
T
N
S
Q
V
S
E
S
L
R
Site 79
S667
T
N
S
Q
V
S
E
S
L
R
Q
L
K
T
K
Site 80
T673
E
S
L
R
Q
L
K
T
K
E
Q
E
D
D
L
Site 81
T681
K
E
Q
E
D
D
L
T
S
Q
T
L
F
V
L
Site 82
S682
E
Q
E
D
D
L
T
S
Q
T
L
F
V
L
K
Site 83
S699
K
I
R
F
P
G
K
S
D
A
E
S
E
L
L
Site 84
S703
P
G
K
S
D
A
E
S
E
L
L
I
E
D
I
Site 85
Y716
D
I
I
D
N
W
K
Y
H
K
T
K
V
A
S
Site 86
S731
Y
W
L
I
K
L
D
S
V
K
Q
R
K
V
L
Site 87
Y764
D
V
E
E
V
N
L
Y
R
I
F
N
R
V
F
Site 88
S795
D
S
G
S
S
W
E
S
I
F
N
K
S
P
E
Site 89
S800
W
E
S
I
F
N
K
S
P
E
V
V
T
P
L
Site 90
T805
N
K
S
P
E
V
V
T
P
L
Q
L
Q
C
C
Site 91
Y829
C
L
L
V
V
Y
K
Y
A
T
D
K
R
G
S
Site 92
T831
L
V
V
Y
K
Y
A
T
D
K
R
G
S
L
S
Site 93
S836
Y
A
T
D
K
R
G
S
L
S
G
I
G
P
D
Site 94
S838
T
D
K
R
G
S
L
S
G
I
G
P
D
W
G
Site 95
S847
I
G
P
D
W
G
N
S
R
Y
L
L
P
G
S
Site 96
Y849
P
D
W
G
N
S
R
Y
L
L
P
G
S
T
Q
Site 97
S854
S
R
Y
L
L
P
G
S
T
Q
F
F
L
R
T
Site 98
T861
S
T
Q
F
F
L
R
T
P
T
Y
N
L
K
Y
Site 99
T863
Q
F
F
L
R
T
P
T
Y
N
L
K
Y
N
S
Site 100
Y864
F
F
L
R
T
P
T
Y
N
L
K
Y
N
S
P
Site 101
Y868
T
P
T
Y
N
L
K
Y
N
S
P
G
M
T
R
Site 102
S870
T
Y
N
L
K
Y
N
S
P
G
M
T
R
S
N
Site 103
T874
K
Y
N
S
P
G
M
T
R
S
N
V
L
F
T
Site 104
S876
N
S
P
G
M
T
R
S
N
V
L
F
T
S
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation