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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GM879
Full Name:
Protein shisa-6 homolog
Alias:
FLJ45455; shisa 6
Type:
Unknown function
Mass (Da):
55746
Number AA:
500
UniProt ID:
Q6ZSJ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
E
S
L
D
L
L
P
S
V
H
G
A
R
G
R
Site 2
T61
G
G
R
E
L
N
G
T
A
R
A
P
G
I
P
Site 3
T234
I
A
H
C
E
R
E
T
I
S
A
I
D
T
S
Site 4
S236
H
C
E
R
E
T
I
S
A
I
D
T
S
P
K
Site 5
T240
E
T
I
S
A
I
D
T
S
P
K
E
N
T
P
Site 6
S241
T
I
S
A
I
D
T
S
P
K
E
N
T
P
V
Site 7
T246
D
T
S
P
K
E
N
T
P
V
R
S
S
S
K
Site 8
S250
K
E
N
T
P
V
R
S
S
S
K
N
H
Y
T
Site 9
S251
E
N
T
P
V
R
S
S
S
K
N
H
Y
T
P
Site 10
S252
N
T
P
V
R
S
S
S
K
N
H
Y
T
P
V
Site 11
Y256
R
S
S
S
K
N
H
Y
T
P
V
R
T
A
K
Site 12
T257
S
S
S
K
N
H
Y
T
P
V
R
T
A
K
Q
Site 13
T261
N
H
Y
T
P
V
R
T
A
K
Q
T
P
E
K
Site 14
T265
P
V
R
T
A
K
Q
T
P
E
K
P
R
M
N
Site 15
T276
P
R
M
N
N
I
L
T
S
A
T
E
P
Y
D
Site 16
S285
A
T
E
P
Y
D
L
S
F
S
R
S
F
Q
N
Site 17
S289
Y
D
L
S
F
S
R
S
F
Q
N
L
A
H
L
Site 18
S299
N
L
A
H
L
P
P
S
Y
E
S
A
V
K
T
Site 19
Y300
L
A
H
L
P
P
S
Y
E
S
A
V
K
T
N
Site 20
T306
S
Y
E
S
A
V
K
T
N
P
S
K
Y
S
S
Site 21
S309
S
A
V
K
T
N
P
S
K
Y
S
S
L
K
R
Site 22
S313
T
N
P
S
K
Y
S
S
L
K
R
L
T
D
K
Site 23
T318
Y
S
S
L
K
R
L
T
D
K
E
A
D
E
Y
Site 24
Y325
T
D
K
E
A
D
E
Y
Y
M
R
R
R
H
L
Site 25
Y326
D
K
E
A
D
E
Y
Y
M
R
R
R
H
L
P
Site 26
S349
P
L
N
V
I
Q
M
S
Q
Q
K
P
L
P
R
Site 27
S367
R
R
P
I
R
A
M
S
Q
D
R
V
L
S
P
Site 28
S373
M
S
Q
D
R
V
L
S
P
D
R
G
L
P
D
Site 29
S383
R
G
L
P
D
E
F
S
M
P
Y
D
R
I
L
Site 30
Y386
P
D
E
F
S
M
P
Y
D
R
I
L
S
D
E
Site 31
S391
M
P
Y
D
R
I
L
S
D
E
Q
L
L
S
T
Site 32
S397
L
S
D
E
Q
L
L
S
T
E
R
L
H
S
Q
Site 33
T398
S
D
E
Q
L
L
S
T
E
R
L
H
S
Q
D
Site 34
S403
L
S
T
E
R
L
H
S
Q
D
P
L
L
S
P
Site 35
S409
H
S
Q
D
P
L
L
S
P
E
R
T
A
F
P
Site 36
T413
P
L
L
S
P
E
R
T
A
F
P
E
Q
S
L
Site 37
S419
R
T
A
F
P
E
Q
S
L
S
R
A
I
S
H
Site 38
S421
A
F
P
E
Q
S
L
S
R
A
I
S
H
T
D
Site 39
S425
Q
S
L
S
R
A
I
S
H
T
D
V
F
V
S
Site 40
T427
L
S
R
A
I
S
H
T
D
V
F
V
S
T
P
Site 41
T433
H
T
D
V
F
V
S
T
P
V
L
D
R
Y
R
Site 42
Y439
S
T
P
V
L
D
R
Y
R
M
S
K
M
H
S
Site 43
S442
V
L
D
R
Y
R
M
S
K
M
H
S
H
P
S
Site 44
S446
Y
R
M
S
K
M
H
S
H
P
S
A
S
N
N
Site 45
S449
S
K
M
H
S
H
P
S
A
S
N
N
S
Y
A
Site 46
S454
H
P
S
A
S
N
N
S
Y
A
T
L
G
Q
S
Site 47
Y455
P
S
A
S
N
N
S
Y
A
T
L
G
Q
S
Q
Site 48
S461
S
Y
A
T
L
G
Q
S
Q
T
A
A
K
R
H
Site 49
T463
A
T
L
G
Q
S
Q
T
A
A
K
R
H
A
F
Site 50
S472
A
K
R
H
A
F
A
S
R
R
H
N
T
V
E
Site 51
T477
F
A
S
R
R
H
N
T
V
E
Q
L
H
Y
I
Site 52
Y491
I
P
G
H
H
T
C
Y
T
A
S
K
T
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation