KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FAM196A
Full Name:
Protein FAM196A
Alias:
Type:
Mass (Da):
52909
Number AA:
479
UniProt ID:
Q6ZSG2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
D
T
G
K
C
I
L
T
T
S
E
S
E
V
E
Site 2
S14
G
K
C
I
L
T
T
S
E
S
E
V
E
P
A
Site 3
T62
A
Q
N
E
Q
R
D
T
Q
L
S
S
G
Q
L
Site 4
S65
E
Q
R
D
T
Q
L
S
S
G
Q
L
G
E
K
Site 5
S79
K
R
E
A
K
P
V
S
C
R
A
A
Y
R
K
Site 6
Y84
P
V
S
C
R
A
A
Y
R
K
Y
M
T
V
P
Site 7
Y87
C
R
A
A
Y
R
K
Y
M
T
V
P
A
R
R
Site 8
S95
M
T
V
P
A
R
R
S
I
P
N
V
T
K
S
Site 9
T100
R
R
S
I
P
N
V
T
K
S
T
G
V
Q
T
Site 10
S102
S
I
P
N
V
T
K
S
T
G
V
Q
T
S
P
Site 11
T103
I
P
N
V
T
K
S
T
G
V
Q
T
S
P
D
Site 12
S108
K
S
T
G
V
Q
T
S
P
D
L
K
K
C
Y
Site 13
Y115
S
P
D
L
K
K
C
Y
Q
T
F
P
L
D
R
Site 14
S129
R
K
K
G
N
L
K
S
L
P
A
A
D
P
F
Site 15
S138
P
A
A
D
P
F
K
S
Q
N
N
G
F
L
T
Site 16
T145
S
Q
N
N
G
F
L
T
D
A
K
E
K
N
E
Site 17
T170
G
A
G
R
V
H
K
T
T
A
L
V
F
H
S
Site 18
T171
A
G
R
V
H
K
T
T
A
L
V
F
H
S
N
Site 19
T183
H
S
N
Q
H
M
N
T
V
D
Q
P
L
G
V
Site 20
T193
Q
P
L
G
V
N
C
T
E
P
C
K
S
P
E
Site 21
S198
N
C
T
E
P
C
K
S
P
E
P
L
S
Y
G
Site 22
S203
C
K
S
P
E
P
L
S
Y
G
E
A
A
L
Q
Site 23
Y204
K
S
P
E
P
L
S
Y
G
E
A
A
L
Q
N
Site 24
S212
G
E
A
A
L
Q
N
S
T
R
P
P
S
E
E
Site 25
T213
E
A
A
L
Q
N
S
T
R
P
P
S
E
E
P
Site 26
S217
Q
N
S
T
R
P
P
S
E
E
P
D
Y
Q
L
Site 27
Y222
P
P
S
E
E
P
D
Y
Q
L
L
G
R
A
K
Site 28
S237
Q
D
R
G
R
P
N
S
E
E
P
A
P
P
A
Site 29
S262
T
V
Y
A
P
A
L
S
A
R
A
P
E
P
G
Site 30
S271
R
A
P
E
P
G
L
S
D
S
A
A
A
S
Q
Site 31
S273
P
E
P
G
L
S
D
S
A
A
A
S
Q
W
S
Site 32
S280
S
A
A
A
S
Q
W
S
L
C
P
A
D
D
E
Site 33
T292
D
D
E
R
R
R
A
T
H
L
N
G
L
Q
A
Site 34
S315
S
P
P
M
Q
C
L
S
P
E
C
S
E
Q
P
Site 35
S319
Q
C
L
S
P
E
C
S
E
Q
P
S
Q
T
H
Site 36
S323
P
E
C
S
E
Q
P
S
Q
T
H
T
P
P
G
Site 37
T325
C
S
E
Q
P
S
Q
T
H
T
P
P
G
L
G
Site 38
T327
E
Q
P
S
Q
T
H
T
P
P
G
L
G
N
Q
Site 39
S336
P
G
L
G
N
Q
P
S
P
T
A
V
A
A
G
Site 40
S370
Q
M
M
E
N
L
I
S
S
S
Q
E
T
I
K
Site 41
S397
E
A
H
R
E
G
L
S
Y
R
T
G
Q
D
T
Site 42
Y398
A
H
R
E
G
L
S
Y
R
T
G
Q
D
T
A
Site 43
T400
R
E
G
L
S
Y
R
T
G
Q
D
T
A
N
C
Site 44
T404
S
Y
R
T
G
Q
D
T
A
N
C
D
T
C
R
Site 45
T409
Q
D
T
A
N
C
D
T
C
R
N
S
A
C
I
Site 46
S449
E
E
T
Q
V
I
P
S
P
Y
S
Q
E
T
Y
Site 47
S452
Q
V
I
P
S
P
Y
S
Q
E
T
Y
S
S
T
Site 48
T455
P
S
P
Y
S
Q
E
T
Y
S
S
T
P
K
Q
Site 49
Y456
S
P
Y
S
Q
E
T
Y
S
S
T
P
K
Q
K
Site 50
S457
P
Y
S
Q
E
T
Y
S
S
T
P
K
Q
K
S
Site 51
S458
Y
S
Q
E
T
Y
S
S
T
P
K
Q
K
S
K
Site 52
T459
S
Q
E
T
Y
S
S
T
P
K
Q
K
S
K
T
Site 53
S464
S
S
T
P
K
Q
K
S
K
T
E
S
K
K
H
Site 54
T466
T
P
K
Q
K
S
K
T
E
S
K
K
H
G
R
Site 55
S468
K
Q
K
S
K
T
E
S
K
K
H
G
R
W
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation