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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF509
Full Name:
Zinc finger and BTB domain-containing protein 49
Alias:
ZN509
Type:
Mass (Da):
85062
Number AA:
765
UniProt ID:
Q6ZSB9
International Prot ID:
IPI00152157
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
A
F
S
Q
Y
F
R
S
L
F
Q
N
S
S
S
Site 2
S57
F
R
S
L
F
Q
N
S
S
S
Q
K
N
D
V
Site 3
S58
R
S
L
F
Q
N
S
S
S
Q
K
N
D
V
F
Site 4
S59
S
L
F
Q
N
S
S
S
Q
K
N
D
V
F
H
Site 5
Y83
G
Q
I
L
D
F
M
Y
T
S
H
L
D
L
N
Site 6
S132
P
P
G
M
P
C
N
S
T
L
S
L
Q
S
T
Site 7
T133
P
G
M
P
C
N
S
T
L
S
L
Q
S
T
L
Site 8
S135
M
P
C
N
S
T
L
S
L
Q
S
T
L
T
P
Site 9
T139
S
T
L
S
L
Q
S
T
L
T
P
D
A
T
C
Site 10
T145
S
T
L
T
P
D
A
T
C
V
I
S
E
N
Y
Site 11
Y152
T
C
V
I
S
E
N
Y
P
P
H
L
L
Q
E
Site 12
S161
P
H
L
L
Q
E
C
S
A
D
A
Q
Q
N
K
Site 13
T169
A
D
A
Q
Q
N
K
T
L
D
E
S
H
P
H
Site 14
S173
Q
N
K
T
L
D
E
S
H
P
H
A
S
P
S
Site 15
S178
D
E
S
H
P
H
A
S
P
S
V
N
R
H
H
Site 16
S180
S
H
P
H
A
S
P
S
V
N
R
H
H
S
A
Site 17
S186
P
S
V
N
R
H
H
S
A
G
E
I
S
K
Q
Site 18
T197
I
S
K
Q
A
P
D
T
S
D
G
S
C
T
E
Site 19
S198
S
K
Q
A
P
D
T
S
D
G
S
C
T
E
L
Site 20
S201
A
P
D
T
S
D
G
S
C
T
E
L
P
F
K
Site 21
T203
D
T
S
D
G
S
C
T
E
L
P
F
K
Q
P
Site 22
Y212
L
P
F
K
Q
P
N
Y
Y
Y
K
L
R
N
F
Site 23
Y213
P
F
K
Q
P
N
Y
Y
Y
K
L
R
N
F
Y
Site 24
Y214
F
K
Q
P
N
Y
Y
Y
K
L
R
N
F
Y
S
Site 25
Y220
Y
Y
K
L
R
N
F
Y
S
K
Q
Y
H
K
H
Site 26
S232
H
K
H
A
A
G
P
S
Q
E
R
V
V
E
Q
Site 27
T250
F
S
T
S
T
D
L
T
T
V
E
S
Q
P
C
Site 28
T251
S
T
S
T
D
L
T
T
V
E
S
Q
P
C
A
Site 29
S254
T
D
L
T
T
V
E
S
Q
P
C
A
V
S
H
Site 30
S260
E
S
Q
P
C
A
V
S
H
S
E
C
I
L
E
Site 31
S262
Q
P
C
A
V
S
H
S
E
C
I
L
E
S
P
Site 32
S268
H
S
E
C
I
L
E
S
P
E
H
L
P
S
N
Site 33
S274
E
S
P
E
H
L
P
S
N
F
L
A
Q
P
V
Site 34
S284
L
A
Q
P
V
N
D
S
A
P
H
P
E
S
D
Site 35
S290
D
S
A
P
H
P
E
S
D
A
T
C
Q
Q
P
Site 36
T293
P
H
P
E
S
D
A
T
C
Q
Q
P
V
K
Q
Site 37
S317
K
K
L
N
F
L
K
S
Q
K
Y
A
E
Q
V
Site 38
Y320
N
F
L
K
S
Q
K
Y
A
E
Q
V
S
E
P
Site 39
S325
Q
K
Y
A
E
Q
V
S
E
P
K
S
D
D
G
Site 40
S329
E
Q
V
S
E
P
K
S
D
D
G
L
T
K
R
Site 41
T334
P
K
S
D
D
G
L
T
K
R
L
E
S
A
S
Site 42
S339
G
L
T
K
R
L
E
S
A
S
K
N
T
L
E
Site 43
S341
T
K
R
L
E
S
A
S
K
N
T
L
E
K
A
Site 44
T344
L
E
S
A
S
K
N
T
L
E
K
A
S
S
Q
Site 45
S350
N
T
L
E
K
A
S
S
Q
S
A
E
E
K
E
Site 46
S358
Q
S
A
E
E
K
E
S
E
E
V
V
S
C
E
Site 47
T373
N
F
N
C
I
S
E
T
E
R
P
E
D
P
A
Site 48
S386
P
A
A
L
E
D
Q
S
Q
T
L
Q
S
Q
R
Site 49
S391
D
Q
S
Q
T
L
Q
S
Q
R
Q
Y
A
C
E
Site 50
Y395
T
L
Q
S
Q
R
Q
Y
A
C
E
L
C
G
K
Site 51
S408
G
K
P
F
K
H
P
S
N
L
E
L
H
K
R
Site 52
T418
E
L
H
K
R
S
H
T
G
E
K
P
F
E
C
Site 53
T440
S
Q
A
G
N
L
Q
T
H
L
R
R
H
S
G
Site 54
S446
Q
T
H
L
R
R
H
S
G
E
E
P
Y
I
C
Site 55
Y451
R
H
S
G
E
E
P
Y
I
C
E
I
C
G
K
Site 56
S489
D
I
C
G
R
G
F
S
N
F
S
N
L
K
E
Site 57
T500
N
L
K
E
H
K
K
T
H
T
A
D
K
V
F
Site 58
T530
V
K
H
R
I
R
H
T
G
E
R
P
Y
S
C
Site 59
Y535
R
H
T
G
E
R
P
Y
S
C
S
A
C
G
K
Site 60
S536
H
T
G
E
R
P
Y
S
C
S
A
C
G
K
C
Site 61
S547
C
G
K
C
F
G
G
S
G
D
L
R
R
H
V
Site 62
T556
D
L
R
R
H
V
R
T
H
T
G
E
K
P
Y
Site 63
T558
R
R
H
V
R
T
H
T
G
E
K
P
Y
T
C
Site 64
T564
H
T
G
E
K
P
Y
T
C
E
I
C
N
K
C
Site 65
S592
H
C
K
A
G
D
E
S
P
D
V
L
E
E
L
Site 66
S600
P
D
V
L
E
E
L
S
Q
A
I
E
T
S
D
Site 67
S606
L
S
Q
A
I
E
T
S
D
L
E
K
S
Q
S
Site 68
S611
E
T
S
D
L
E
K
S
Q
S
S
D
S
F
S
Site 69
S613
S
D
L
E
K
S
Q
S
S
D
S
F
S
Q
D
Site 70
S614
D
L
E
K
S
Q
S
S
D
S
F
S
Q
D
T
Site 71
S616
E
K
S
Q
S
S
D
S
F
S
Q
D
T
S
V
Site 72
S618
S
Q
S
S
D
S
F
S
Q
D
T
S
V
T
L
Site 73
S622
D
S
F
S
Q
D
T
S
V
T
L
M
P
V
S
Site 74
S640
P
V
H
P
V
E
N
S
V
A
E
F
D
S
H
Site 75
S646
N
S
V
A
E
F
D
S
H
S
G
G
S
Y
C
Site 76
S648
V
A
E
F
D
S
H
S
G
G
S
Y
C
K
L
Site 77
S651
F
D
S
H
S
G
G
S
Y
C
K
L
R
S
M
Site 78
Y652
D
S
H
S
G
G
S
Y
C
K
L
R
S
M
I
Site 79
S657
G
S
Y
C
K
L
R
S
M
I
Q
P
H
G
V
Site 80
S665
M
I
Q
P
H
G
V
S
D
Q
E
K
L
S
L
Site 81
S671
V
S
D
Q
E
K
L
S
L
D
P
G
K
L
A
Site 82
T697
Y
A
Y
S
D
V
D
T
P
A
G
G
E
P
L
Site 83
S729
H
G
G
D
P
L
G
S
R
A
S
S
T
T
Y
Site 84
S732
D
P
L
G
S
R
A
S
S
T
T
Y
R
N
S
Site 85
S733
P
L
G
S
R
A
S
S
T
T
Y
R
N
S
E
Site 86
T734
L
G
S
R
A
S
S
T
T
Y
R
N
S
E
G
Site 87
T735
G
S
R
A
S
S
T
T
Y
R
N
S
E
G
Q
Site 88
Y736
S
R
A
S
S
T
T
Y
R
N
S
E
G
Q
F
Site 89
S739
S
S
T
T
Y
R
N
S
E
G
Q
F
F
S
S
Site 90
S745
N
S
E
G
Q
F
F
S
S
M
T
L
W
G
L
Site 91
T756
L
W
G
L
A
M
K
T
L
Q
N
E
N
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation