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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC73
Full Name:
Coiled-coil domain-containing protein 73
Alias:
Sarcoma antigen NY-SAR-79
Type:
Mass (Da):
124154
Number AA:
1079
UniProt ID:
Q6ZRK6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
E
S
N
F
N
T
E
S
S
S
T
F
T
Site 2
S9
E
S
N
F
N
T
E
S
S
S
T
F
T
L
Q
Site 3
S10
S
N
F
N
T
E
S
S
S
T
F
T
L
Q
S
Site 4
S11
N
F
N
T
E
S
S
S
T
F
T
L
Q
S
S
Site 5
T12
F
N
T
E
S
S
S
T
F
T
L
Q
S
S
S
Site 6
T14
T
E
S
S
S
T
F
T
L
Q
S
S
S
E
T
Site 7
S17
S
S
T
F
T
L
Q
S
S
S
E
T
L
F
S
Site 8
S19
T
F
T
L
Q
S
S
S
E
T
L
F
S
I
Q
Site 9
S24
S
S
S
E
T
L
F
S
I
Q
L
L
D
F
K
Site 10
S33
Q
L
L
D
F
K
T
S
L
L
E
A
L
E
E
Site 11
Y51
R
R
E
A
E
I
H
Y
E
E
Q
I
G
K
I
Site 12
Y108
L
E
E
E
K
G
K
Y
Q
L
A
T
E
I
K
Site 13
S135
A
L
Q
V
S
K
Y
S
L
Q
K
K
V
S
E
Site 14
Y157
H
L
L
A
K
E
D
Y
H
K
Q
L
S
E
I
Site 15
S162
E
D
Y
H
K
Q
L
S
E
I
E
K
Y
Y
A
Site 16
Y167
Q
L
S
E
I
E
K
Y
Y
A
T
I
T
G
Q
Site 17
Y168
L
S
E
I
E
K
Y
Y
A
T
I
T
G
Q
F
Site 18
S195
N
V
R
E
A
I
Q
S
N
K
R
L
S
A
L
Site 19
S200
I
Q
S
N
K
R
L
S
A
L
N
K
K
Q
E
Site 20
S222
K
E
L
K
K
A
A
S
D
L
I
K
S
K
V
Site 21
T314
V
L
K
E
N
N
Q
T
L
E
R
D
N
E
L
Site 22
S366
N
K
I
K
N
E
L
S
S
L
K
E
T
H
I
Site 23
T371
E
L
S
S
L
K
E
T
H
I
K
L
Q
E
H
Site 24
T387
N
K
L
C
N
Q
K
T
F
E
E
D
K
K
F
Site 25
T409
N
E
N
S
E
M
S
T
E
K
S
E
N
T
I
Site 26
S412
S
E
M
S
T
E
K
S
E
N
T
I
I
Q
K
Site 27
Y420
E
N
T
I
I
Q
K
Y
N
T
E
Q
E
I
R
Site 28
S436
E
N
M
E
N
F
C
S
D
T
E
Y
R
E
K
Site 29
T438
M
E
N
F
C
S
D
T
E
Y
R
E
K
E
E
Site 30
Y440
N
F
C
S
D
T
E
Y
R
E
K
E
E
K
K
Site 31
S450
K
E
E
K
K
E
G
S
F
I
E
E
I
I
I
Site 32
S466
D
L
Q
L
F
E
K
S
F
K
N
E
I
D
T
Site 33
T473
S
F
K
N
E
I
D
T
V
V
S
Q
D
E
N
Site 34
S476
N
E
I
D
T
V
V
S
Q
D
E
N
Q
S
E
Site 35
S482
V
S
Q
D
E
N
Q
S
E
I
S
L
S
K
T
Site 36
S485
D
E
N
Q
S
E
I
S
L
S
K
T
L
S
L
Site 37
S487
N
Q
S
E
I
S
L
S
K
T
L
S
L
D
K
Site 38
T489
S
E
I
S
L
S
K
T
L
S
L
D
K
E
V
Site 39
S498
S
L
D
K
E
V
I
S
Q
G
Q
T
S
N
V
Site 40
T506
Q
G
Q
T
S
N
V
T
D
N
R
K
S
V
T
Site 41
S511
N
V
T
D
N
R
K
S
V
T
T
E
I
K
D
Site 42
T514
D
N
R
K
S
V
T
T
E
I
K
D
K
I
C
Site 43
T563
R
G
L
D
V
H
H
T
D
V
N
L
E
V
E
Site 44
T574
L
E
V
E
N
N
K
T
S
F
N
S
I
L
N
Site 45
S575
E
V
E
N
N
K
T
S
F
N
S
I
L
N
E
Site 46
T610
Q
F
R
L
L
P
G
T
R
E
H
A
L
E
K
Site 47
T620
H
A
L
E
K
E
I
T
N
S
D
Q
T
K
A
Site 48
S622
L
E
K
E
I
T
N
S
D
Q
T
K
A
D
L
Site 49
S631
Q
T
K
A
D
L
D
S
S
L
D
I
K
K
N
Site 50
S632
T
K
A
D
L
D
S
S
L
D
I
K
K
N
P
Site 51
Y645
N
P
V
P
C
Q
K
Y
S
L
R
N
S
S
N
Site 52
S646
P
V
P
C
Q
K
Y
S
L
R
N
S
S
N
V
Site 53
S650
Q
K
Y
S
L
R
N
S
S
N
V
M
L
D
D
Site 54
S651
K
Y
S
L
R
N
S
S
N
V
M
L
D
D
K
Site 55
S679
S
E
C
S
I
L
L
S
K
Q
T
S
D
F
L
Site 56
T692
F
L
Q
V
C
N
D
T
L
E
K
S
E
L
T
Site 57
S696
C
N
D
T
L
E
K
S
E
L
T
V
P
C
D
Site 58
S726
S
K
L
L
L
K
N
S
D
K
N
V
H
S
M
Site 59
S732
N
S
D
K
N
V
H
S
M
S
M
L
V
K
P
Site 60
S734
D
K
N
V
H
S
M
S
M
L
V
K
P
N
S
Site 61
S741
S
M
L
V
K
P
N
S
S
P
G
G
K
T
M
Site 62
S742
M
L
V
K
P
N
S
S
P
G
G
K
T
M
C
Site 63
T747
N
S
S
P
G
G
K
T
M
C
K
N
M
S
D
Site 64
Y766
Q
F
N
N
C
L
G
Y
L
E
N
T
N
V
N
Site 65
S784
L
H
L
N
N
E
N
S
H
A
S
Q
A
K
D
Site 66
T794
S
Q
A
K
D
V
K
T
A
V
H
M
K
T
C
Site 67
T800
K
T
A
V
H
M
K
T
C
T
E
T
E
F
S
Site 68
T802
A
V
H
M
K
T
C
T
E
T
E
F
S
N
K
Site 69
T819
Q
I
D
E
N
Q
V
T
E
A
T
K
N
D
L
Site 70
S831
N
D
L
F
L
F
V
S
I
N
E
R
Q
H
T
Site 71
T838
S
I
N
E
R
Q
H
T
L
L
N
N
T
E
K
Site 72
S848
N
N
T
E
K
T
E
S
L
N
D
I
V
S
G
Site 73
S854
E
S
L
N
D
I
V
S
G
K
M
F
S
E
G
Site 74
S866
S
E
G
Q
L
E
E
S
H
S
F
H
I
E
P
Site 75
S868
G
Q
L
E
E
S
H
S
F
H
I
E
P
S
G
Site 76
S881
S
G
D
L
V
N
R
S
G
R
S
T
F
D
L
Site 77
S884
L
V
N
R
S
G
R
S
T
F
D
L
S
T
S
Site 78
T885
V
N
R
S
G
R
S
T
F
D
L
S
T
S
D
Site 79
S889
G
R
S
T
F
D
L
S
T
S
D
K
K
T
E
Site 80
T890
R
S
T
F
D
L
S
T
S
D
K
K
T
E
K
Site 81
S891
S
T
F
D
L
S
T
S
D
K
K
T
E
K
T
Site 82
T895
L
S
T
S
D
K
K
T
E
K
T
P
V
Y
M
Site 83
T898
S
D
K
K
T
E
K
T
P
V
Y
M
N
F
S
Site 84
Y901
K
T
E
K
T
P
V
Y
M
N
F
S
D
P
G
Site 85
S905
T
P
V
Y
M
N
F
S
D
P
G
P
W
S
K
Site 86
S911
F
S
D
P
G
P
W
S
K
V
N
H
I
E
S
Site 87
S918
S
K
V
N
H
I
E
S
Q
T
A
S
S
S
T
Site 88
T920
V
N
H
I
E
S
Q
T
A
S
S
S
T
P
C
Site 89
S922
H
I
E
S
Q
T
A
S
S
S
T
P
C
I
S
Site 90
S923
I
E
S
Q
T
A
S
S
S
T
P
C
I
S
L
Site 91
S924
E
S
Q
T
A
S
S
S
T
P
C
I
S
L
L
Site 92
S929
S
S
S
T
P
C
I
S
L
L
L
K
E
R
P
Site 93
S940
K
E
R
P
L
D
P
S
E
N
K
K
I
I
S
Site 94
T967
G
K
D
I
G
P
D
T
T
S
I
N
R
V
A
Site 95
S969
D
I
G
P
D
T
T
S
I
N
R
V
A
D
T
Site 96
T1000
E
K
N
A
M
A
K
T
F
Y
D
S
S
F
P
Site 97
Y1002
N
A
M
A
K
T
F
Y
D
S
S
F
P
T
E
Site 98
S1004
M
A
K
T
F
Y
D
S
S
F
P
T
E
H
V
Site 99
S1005
A
K
T
F
Y
D
S
S
F
P
T
E
H
V
K
Site 100
T1008
F
Y
D
S
S
F
P
T
E
H
V
K
T
K
P
Site 101
T1013
F
P
T
E
H
V
K
T
K
P
L
I
S
T
P
Site 102
S1018
V
K
T
K
P
L
I
S
T
P
L
Q
S
H
L
Site 103
T1019
K
T
K
P
L
I
S
T
P
L
Q
S
H
L
Q
Site 104
T1030
S
H
L
Q
A
I
K
T
T
K
N
T
S
G
D
Site 105
S1042
S
G
D
D
D
W
Q
S
L
I
T
N
Q
L
N
Site 106
S1051
I
T
N
Q
L
N
K
S
E
N
L
L
S
L
E
Site 107
S1056
N
K
S
E
N
L
L
S
L
E
N
D
N
Q
P
Site 108
T1071
K
K
R
K
A
E
E
T
L
E
K
N
N
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation