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Updated November 2019
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Protein Info
Short Name:
ZNF493
Full Name:
Zinc finger protein 493
Alias:
Type:
Mass (Da):
75342
Number AA:
646
UniProt ID:
Q6ZR52
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
G
Y
N
E
L
N
Q
Y
L
T
T
T
Q
S
K
Site 2
T19
N
E
L
N
Q
Y
L
T
T
T
Q
S
K
I
F
Site 3
T20
E
L
N
Q
Y
L
T
T
T
Q
S
K
I
F
Q
Site 4
T21
L
N
Q
Y
L
T
T
T
Q
S
K
I
F
Q
C
Site 5
S23
Q
Y
L
T
T
T
Q
S
K
I
F
Q
C
D
K
Site 6
Y31
K
I
F
Q
C
D
K
Y
V
K
V
F
H
K
L
Site 7
T46
L
N
S
N
R
H
N
T
K
H
T
G
K
K
P
Site 8
T105
T
R
H
R
R
V
H
T
G
E
K
S
Y
K
Y
Site 9
S109
R
V
H
T
G
E
K
S
Y
K
Y
E
C
G
K
Site 10
Y112
T
G
E
K
S
Y
K
Y
E
C
G
K
S
F
N
Site 11
S122
G
K
S
F
N
Q
D
S
N
L
T
T
H
K
R
Site 12
T126
N
Q
D
S
N
L
T
T
H
K
R
I
H
T
G
Site 13
T132
T
T
H
K
R
I
H
T
G
Q
K
P
Y
K
C
Site 14
Y137
I
H
T
G
Q
K
P
Y
K
C
E
E
C
G
T
Site 15
Y147
E
E
C
G
T
S
F
Y
Q
F
S
Y
L
T
R
Site 16
S150
G
T
S
F
Y
Q
F
S
Y
L
T
R
H
K
L
Site 17
Y170
K
P
Y
K
C
E
Q
Y
G
K
T
F
N
Q
S
Site 18
T173
K
C
E
Q
Y
G
K
T
F
N
Q
S
S
T
L
Site 19
S177
Y
G
K
T
F
N
Q
S
S
T
L
T
G
H
K
Site 20
S178
G
K
T
F
N
Q
S
S
T
L
T
G
H
K
I
Site 21
T179
K
T
F
N
Q
S
S
T
L
T
G
H
K
I
I
Site 22
T181
F
N
Q
S
S
T
L
T
G
H
K
I
I
H
N
Site 23
Y193
I
H
N
G
E
K
P
Y
K
C
E
E
C
G
K
Site 24
S203
E
E
C
G
K
A
F
S
I
F
S
T
P
T
K
Site 25
S206
G
K
A
F
S
I
F
S
T
P
T
K
H
K
I
Site 26
T207
K
A
F
S
I
F
S
T
P
T
K
H
K
I
I
Site 27
T237
Y
K
E
S
S
H
L
T
T
H
K
R
I
H
T
Site 28
T238
K
E
S
S
H
L
T
T
H
K
R
I
H
T
G
Site 29
T244
T
T
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 30
S259
E
E
C
G
K
A
F
S
I
F
S
T
L
T
K
Site 31
S289
C
G
K
A
Y
K
E
S
S
H
L
T
T
H
K
Site 32
S290
G
K
A
Y
K
E
S
S
H
L
T
T
H
K
R
Site 33
Y333
I
H
T
E
E
K
P
Y
K
C
E
E
C
G
K
Site 34
S346
G
K
A
F
K
R
S
S
T
L
T
K
H
R
I
Site 35
T347
K
A
F
K
R
S
S
T
L
T
K
H
R
I
I
Site 36
T349
F
K
R
S
S
T
L
T
K
H
R
I
I
H
T
Site 37
S373
C
G
K
A
F
N
Q
S
S
T
L
S
I
H
K
Site 38
S374
G
K
A
F
N
Q
S
S
T
L
S
I
H
K
I
Site 39
T375
K
A
F
N
Q
S
S
T
L
S
I
H
K
I
I
Site 40
S377
F
N
Q
S
S
T
L
S
I
H
K
I
I
H
T
Site 41
T384
S
I
H
K
I
I
H
T
G
E
K
P
Y
K
C
Site 42
S401
C
G
K
A
F
K
R
S
S
T
L
T
I
H
K
Site 43
S402
G
K
A
F
K
R
S
S
T
L
T
I
H
K
M
Site 44
T403
K
A
F
K
R
S
S
T
L
T
I
H
K
M
I
Site 45
T405
F
K
R
S
S
T
L
T
I
H
K
M
I
H
T
Site 46
T412
T
I
H
K
M
I
H
T
G
E
K
P
Y
K
C
Site 47
S429
C
G
K
A
F
N
R
S
S
H
L
T
T
H
K
Site 48
S430
G
K
A
F
N
R
S
S
H
L
T
T
H
K
R
Site 49
T433
F
N
R
S
S
H
L
T
T
H
K
R
I
H
T
Site 50
T434
N
R
S
S
H
L
T
T
H
K
R
I
H
T
G
Site 51
T440
T
T
H
K
R
I
H
T
G
H
K
P
Y
K
C
Site 52
Y445
I
H
T
G
H
K
P
Y
K
C
K
E
C
G
K
Site 53
S453
K
C
K
E
C
G
K
S
F
S
V
F
S
T
L
Site 54
S455
K
E
C
G
K
S
F
S
V
F
S
T
L
T
K
Site 55
S485
C
G
K
A
F
N
R
S
S
I
L
S
I
H
K
Site 56
S486
G
K
A
F
N
R
S
S
I
L
S
I
H
K
K
Site 57
S489
F
N
R
S
S
I
L
S
I
H
K
K
I
H
T
Site 58
T496
S
I
H
K
K
I
H
T
G
E
K
P
Y
K
C
Site 59
S513
C
G
K
A
F
K
R
S
S
H
L
A
G
H
K
Site 60
S514
G
K
A
F
K
R
S
S
H
L
A
G
H
K
Q
Site 61
Y557
I
H
T
E
E
K
P
Y
K
C
E
K
C
G
K
Site 62
Y567
E
K
C
G
K
T
F
Y
R
F
S
N
L
N
T
Site 63
S598
G
K
A
F
N
H
S
S
N
L
I
K
H
K
L
Site 64
Y613
I
H
T
G
D
K
P
Y
K
C
E
A
C
G
K
Site 65
S625
C
G
K
A
F
R
R
S
S
H
L
S
R
H
K
Site 66
S626
G
K
A
F
R
R
S
S
H
L
S
R
H
K
I
Site 67
S629
F
R
R
S
S
H
L
S
R
H
K
I
I
H
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation