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Updated November 2019
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Protein Info
Short Name:
WDR87
Full Name:
WD repeat-containing protein 87
Alias:
Testis development protein NYD-SP11
Type:
Mass (Da):
333185
Number AA:
2873
UniProt ID:
Q6ZQQ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
L
K
L
L
L
N
D
T
I
N
K
S
K
Q
P
Site 2
S24
L
N
D
T
I
N
K
S
K
Q
P
S
E
D
P
Site 3
S28
I
N
K
S
K
Q
P
S
E
D
P
K
N
C
L
Site 4
T60
E
D
M
V
E
K
R
T
F
S
M
T
E
R
L
Site 5
S62
M
V
E
K
R
T
F
S
M
T
E
R
L
P
P
Site 6
T64
E
K
R
T
F
S
M
T
E
R
L
P
P
I
Q
Site 7
S72
E
R
L
P
P
I
Q
S
M
V
H
A
G
S
F
Site 8
T197
L
G
E
V
K
R
F
T
S
T
S
S
G
S
S
Site 9
S198
G
E
V
K
R
F
T
S
T
S
S
G
S
S
I
Site 10
T199
E
V
K
R
F
T
S
T
S
S
G
S
S
I
T
Site 11
S200
V
K
R
F
T
S
T
S
S
G
S
S
I
T
C
Site 12
S201
K
R
F
T
S
T
S
S
G
S
S
I
T
C
C
Site 13
Y218
C
F
D
Q
G
F
L
Y
A
G
N
Q
A
G
E
Site 14
S230
A
G
E
I
Q
V
W
S
L
Q
Q
G
H
P
L
Site 15
S239
Q
Q
G
H
P
L
H
S
F
Q
A
H
Q
S
G
Site 16
S252
S
G
V
I
C
I
R
S
R
P
E
A
H
T
L
Site 17
T258
R
S
R
P
E
A
H
T
L
L
T
A
G
S
D
Site 18
S264
H
T
L
L
T
A
G
S
D
S
L
I
K
E
W
Site 19
S266
L
L
T
A
G
S
D
S
L
I
K
E
W
N
L
Site 20
T274
L
I
K
E
W
N
L
T
S
G
S
L
L
R
R
Site 21
S277
E
W
N
L
T
S
G
S
L
L
R
R
L
E
L
Site 22
Y289
L
E
L
G
E
E
L
Y
R
L
Q
F
I
D
S
Site 23
S306
F
F
C
Q
T
A
H
S
F
S
L
H
R
L
P
Site 24
S324
S
L
F
N
V
C
G
S
A
P
Q
Q
L
R
R
Site 25
Y378
D
Q
A
V
D
W
A
Y
D
P
G
K
E
E
L
Site 26
S391
E
L
F
V
A
T
G
S
S
E
V
L
V
F
D
Site 27
S392
L
F
V
A
T
G
S
S
E
V
L
V
F
D
T
Site 28
Y408
R
C
P
C
P
A
K
Y
L
L
G
T
S
P
N
Site 29
S413
A
K
Y
L
L
G
T
S
P
N
S
Q
D
F
V
Site 30
Y494
C
S
Y
G
M
D
D
Y
V
H
L
S
E
A
V
Site 31
S550
W
K
F
H
D
F
L
S
S
G
S
Q
N
G
L
Site 32
S551
K
F
H
D
F
L
S
S
G
S
Q
N
G
L
K
Site 33
S553
H
D
F
L
S
S
G
S
Q
N
G
L
K
F
I
Site 34
S590
V
T
G
S
A
D
G
S
V
R
I
W
D
F
H
Site 35
T625
D
R
G
D
L
L
V
T
F
N
Q
S
L
Y
L
Site 36
Y679
E
T
M
F
V
P
K
Y
I
Y
P
G
Q
A
Q
Site 37
Y681
M
F
V
P
K
Y
I
Y
P
G
Q
A
Q
Q
K
Site 38
S706
R
A
I
A
F
D
H
S
V
P
H
V
I
E
E
Site 39
S718
I
E
E
D
E
E
G
S
P
V
L
L
R
S
S
Site 40
S724
G
S
P
V
L
L
R
S
S
M
H
Y
S
L
Q
Site 41
S725
S
P
V
L
L
R
S
S
M
H
Y
S
L
Q
D
Site 42
Y728
L
L
R
S
S
M
H
Y
S
L
Q
D
M
E
D
Site 43
S729
L
R
S
S
M
H
Y
S
L
Q
D
M
E
D
W
Site 44
Y747
S
K
R
Y
Q
C
H
Y
V
L
P
P
Q
L
Q
Site 45
T756
L
P
P
Q
L
Q
L
T
S
W
D
G
L
N
P
Site 46
S757
P
P
Q
L
Q
L
T
S
W
D
G
L
N
P
Y
Site 47
Y764
S
W
D
G
L
N
P
Y
Q
I
L
R
Y
Y
F
Site 48
Y769
N
P
Y
Q
I
L
R
Y
Y
F
G
H
G
R
E
Site 49
Y770
P
Y
Q
I
L
R
Y
Y
F
G
H
G
R
E
W
Site 50
T799
A
R
L
W
P
E
G
T
P
I
Y
L
Q
C
N
Site 51
Y802
W
P
E
G
T
P
I
Y
L
Q
C
N
L
H
A
Site 52
S833
H
S
R
V
R
A
I
S
N
T
E
Y
P
K
N
Site 53
T835
R
V
R
A
I
S
N
T
E
Y
P
K
N
K
E
Site 54
Y837
R
A
I
S
N
T
E
Y
P
K
N
K
E
E
D
Site 55
S853
H
F
L
E
M
R
L
S
K
D
V
T
Y
S
V
Site 56
T857
M
R
L
S
K
D
V
T
Y
S
V
L
T
D
G
Site 57
Y858
R
L
S
K
D
V
T
Y
S
V
L
T
D
G
A
Site 58
S859
L
S
K
D
V
T
Y
S
V
L
T
D
G
A
N
Site 59
S868
L
T
D
G
A
N
R
S
W
L
G
R
K
M
S
Site 60
S875
S
W
L
G
R
K
M
S
E
I
T
I
N
S
M
Site 61
S915
I
F
A
S
Y
Q
V
S
P
A
L
R
S
E
T
Site 62
T922
S
P
A
L
R
S
E
T
A
R
R
L
L
N
D
Site 63
T930
A
R
R
L
L
N
D
T
T
N
S
N
P
L
I
Site 64
T931
R
R
L
L
N
D
T
T
N
S
N
P
L
I
R
Site 65
T974
D
E
R
V
R
I
K
T
L
S
L
M
A
E
I
Site 66
S985
M
A
E
I
G
I
H
S
R
T
S
L
L
Q
L
Site 67
S988
I
G
I
H
S
R
T
S
L
L
Q
L
T
Q
K
Site 68
T993
R
T
S
L
L
Q
L
T
Q
K
Q
E
T
F
R
Site 69
T998
Q
L
T
Q
K
Q
E
T
F
R
E
M
Q
Q
Q
Site 70
T1039
Q
R
L
N
E
N
L
T
L
S
H
R
D
E
K
Site 71
S1041
L
N
E
N
L
T
L
S
H
R
D
E
K
P
A
Site 72
S1050
R
D
E
K
P
A
F
S
L
D
V
S
M
P
S
Site 73
S1054
P
A
F
S
L
D
V
S
M
P
S
E
L
K
S
Site 74
S1057
S
L
D
V
S
M
P
S
E
L
K
S
S
L
K
Site 75
S1061
S
M
P
S
E
L
K
S
S
L
K
P
P
T
V
Site 76
S1062
M
P
S
E
L
K
S
S
L
K
P
P
T
V
S
Site 77
T1067
K
S
S
L
K
P
P
T
V
S
E
E
S
E
V
Site 78
S1069
S
L
K
P
P
T
V
S
E
E
S
E
V
A
I
Site 79
S1093
Q
A
G
V
K
K
H
S
Q
K
W
L
R
G
L
Site 80
T1103
W
L
R
G
L
K
K
T
K
E
R
D
S
K
Q
Site 81
S1108
K
K
T
K
E
R
D
S
K
Q
M
S
T
E
P
Site 82
S1112
E
R
D
S
K
Q
M
S
T
E
P
G
L
L
E
Site 83
T1113
R
D
S
K
Q
M
S
T
E
P
G
L
L
E
D
Site 84
S1122
P
G
L
L
E
D
E
S
G
T
E
A
A
P
I
Site 85
S1135
P
I
E
M
E
E
A
S
V
Y
S
Q
W
S
S
Site 86
Y1137
E
M
E
E
A
S
V
Y
S
Q
W
S
S
S
T
Site 87
S1138
M
E
E
A
S
V
Y
S
Q
W
S
S
S
T
S
Site 88
S1141
A
S
V
Y
S
Q
W
S
S
S
T
S
V
I
K
Site 89
S1142
S
V
Y
S
Q
W
S
S
S
T
S
V
I
K
L
Site 90
S1143
V
Y
S
Q
W
S
S
S
T
S
V
I
K
L
S
Site 91
S1145
S
Q
W
S
S
S
T
S
V
I
K
L
S
K
D
Site 92
S1150
S
T
S
V
I
K
L
S
K
D
V
D
S
Q
E
Site 93
S1155
K
L
S
K
D
V
D
S
Q
E
K
D
I
S
K
Site 94
S1161
D
S
Q
E
K
D
I
S
K
D
H
I
A
L
T
Site 95
T1168
S
K
D
H
I
A
L
T
L
K
R
L
Q
K
I
Site 96
T1184
D
K
R
D
K
K
A
T
A
Q
K
L
K
K
K
Site 97
T1207
K
V
I
N
E
E
T
T
P
P
V
M
E
Q
P
Site 98
T1216
P
V
M
E
Q
P
V
T
K
K
V
K
I
Q
G
Site 99
S1227
K
I
Q
G
R
G
A
S
G
I
S
G
R
R
S
Site 100
S1230
G
R
G
A
S
G
I
S
G
R
R
S
T
A
G
Site 101
S1234
S
G
I
S
G
R
R
S
T
A
G
D
G
S
S
Site 102
T1235
G
I
S
G
R
R
S
T
A
G
D
G
S
S
W
Site 103
S1241
S
T
A
G
D
G
S
S
W
R
D
D
L
C
R
Site 104
S1255
R
L
M
A
L
R
I
S
G
S
Q
T
K
M
S
Site 105
S1257
M
A
L
R
I
S
G
S
Q
T
K
M
S
E
N
Site 106
T1259
L
R
I
S
G
S
Q
T
K
M
S
E
N
L
N
Site 107
S1283
M
L
V
D
R
H
P
S
W
E
L
F
Q
E
I
Site 108
T1395
S
K
K
E
E
K
K
T
F
Q
K
S
P
K
Q
Site 109
S1399
E
K
K
T
F
Q
K
S
P
K
Q
G
R
K
A
Site 110
T1421
G
K
I
K
R
E
M
T
K
E
E
R
D
M
S
Site 111
S1428
T
K
E
E
R
D
M
S
E
E
V
E
E
M
A
Site 112
T1436
E
E
V
E
E
M
A
T
L
E
E
K
V
V
K
Site 113
T1454
K
L
V
M
I
E
R
T
P
S
W
Q
D
W
K
Site 114
T1474
W
K
Q
V
H
G
E
T
R
K
S
W
K
A
W
Site 115
S1504
H
Q
A
G
E
K
L
S
P
E
E
E
M
L
Q
Site 116
S1530
Q
V
W
E
N
M
L
S
S
K
S
K
E
Q
Q
Site 117
S1531
V
W
E
N
M
L
S
S
K
S
K
E
Q
Q
Y
Site 118
S1533
E
N
M
L
S
S
K
S
K
E
Q
Q
Y
K
D
Site 119
Y1538
S
K
S
K
E
Q
Q
Y
K
D
E
E
E
V
T
Site 120
T1545
Y
K
D
E
E
E
V
T
L
E
E
E
V
S
R
Site 121
S1551
V
T
L
E
E
E
V
S
R
E
G
E
E
K
E
Site 122
T1562
E
E
K
E
Q
Q
V
T
E
E
Q
R
H
I
Q
Site 123
Y1620
E
R
K
L
A
Q
A
Y
V
K
I
T
Q
D
D
Site 124
S1652
A
Q
R
G
E
K
L
S
Q
E
A
E
K
L
A
Site 125
S1729
E
W
D
M
E
E
L
S
W
K
E
E
E
L
N
Site 126
S1764
A
W
Q
R
E
K
L
S
E
E
E
T
K
L
A
Site 127
S1822
K
R
E
R
W
I
N
S
M
E
E
L
T
K
N
Site 128
Y1834
T
K
N
K
M
I
L
Y
Q
K
K
N
L
A
Q
Site 129
Y1862
Q
R
K
E
N
L
L
Y
N
K
E
R
L
T
H
Site 130
T1868
L
Y
N
K
E
R
L
T
H
S
K
K
Q
L
V
Site 131
T1896
A
Q
V
E
E
K
L
T
Q
E
K
E
T
V
I
Site 132
S1922
K
L
V
Q
V
E
D
S
L
A
K
K
Q
E
K
Site 133
T1983
R
L
V
E
G
K
E
T
L
S
K
G
E
T
P
Site 134
S1985
V
E
G
K
E
T
L
S
K
G
E
T
P
E
T
Site 135
T1989
E
T
L
S
K
G
E
T
P
E
T
S
R
Q
R
Site 136
T1992
S
K
G
E
T
P
E
T
S
R
Q
R
K
M
T
Site 137
S1993
K
G
E
T
P
E
T
S
R
Q
R
K
M
T
Q
Site 138
T1999
T
S
R
Q
R
K
M
T
Q
V
E
Q
E
L
F
Site 139
S2011
E
L
F
E
R
K
L
S
L
E
E
K
I
L
L
Site 140
S2029
R
I
L
A
M
E
E
S
E
I
A
K
G
K
L
Site 141
S2065
K
L
I
K
K
R
E
S
L
S
K
E
P
A
K
Site 142
S2067
I
K
K
R
E
S
L
S
K
E
P
A
K
L
N
Site 143
T2091
T
R
D
E
R
K
L
T
Q
E
E
I
K
M
T
Site 144
T2098
T
Q
E
E
I
K
M
T
K
M
K
R
A
L
F
Site 145
S2112
F
V
K
E
R
R
L
S
I
E
Q
S
K
L
D
Site 146
S2116
R
R
L
S
I
E
Q
S
K
L
D
I
K
E
W
Site 147
S2126
D
I
K
E
W
D
F
S
E
K
R
S
E
L
T
Site 148
S2130
W
D
F
S
E
K
R
S
E
L
T
K
D
E
K
Site 149
T2161
I
N
K
E
E
K
M
T
E
E
E
S
K
L
A
Site 150
S2172
S
K
L
A
R
K
H
S
E
V
I
L
D
D
E
Site 151
S2215
K
P
K
E
K
F
S
S
Q
V
D
E
V
E
S
Site 152
S2222
S
Q
V
D
E
V
E
S
E
E
H
F
S
E
E
Site 153
S2227
V
E
S
E
E
H
F
S
E
E
M
E
S
L
L
Site 154
S2232
H
F
S
E
E
M
E
S
L
L
D
E
L
E
K
Site 155
S2242
D
E
L
E
K
Q
E
S
L
S
S
E
E
E
E
Site 156
S2244
L
E
K
Q
E
S
L
S
S
E
E
E
E
E
R
Site 157
S2245
E
K
Q
E
S
L
S
S
E
E
E
E
E
R
E
Site 158
S2314
E
E
K
E
E
I
M
S
E
E
E
T
E
S
L
Site 159
T2318
E
I
M
S
E
E
E
T
E
S
L
S
D
E
E
Site 160
S2320
M
S
E
E
E
T
E
S
L
S
D
E
E
E
E
Site 161
S2322
E
E
E
T
E
S
L
S
D
E
E
E
E
E
E
Site 162
S2330
D
E
E
E
E
E
E
S
C
S
L
E
E
E
V
Site 163
S2332
E
E
E
E
E
S
C
S
L
E
E
E
V
D
R
Site 164
S2359
L
Q
E
Q
R
R
K
S
L
R
G
R
E
R
V
Site 165
S2368
R
G
R
E
R
V
L
S
I
L
R
G
V
P
H
Site 166
S2395
S
P
L
K
K
L
M
S
T
A
L
E
M
K
E
Site 167
T2404
A
L
E
M
K
E
K
T
P
V
P
V
P
E
K
Site 168
S2414
P
V
P
E
K
Q
I
S
W
E
D
K
K
A
T
Site 169
T2421
S
W
E
D
K
K
A
T
V
V
E
I
P
R
K
Site 170
T2432
I
P
R
K
F
L
G
T
M
D
K
E
R
E
V
Site 171
Y2443
E
R
E
V
M
G
K
Y
E
P
I
P
P
H
V
Site 172
S2457
V
L
G
T
V
L
E
S
Q
A
Q
D
L
K
T
Site 173
T2464
S
Q
A
Q
D
L
K
T
P
F
M
S
H
I
L
Site 174
T2474
M
S
H
I
L
R
R
T
V
E
A
E
E
L
Q
Site 175
S2509
T
E
V
Q
L
P
L
S
Q
I
P
A
K
E
Q
Site 176
S2521
K
E
Q
H
A
D
V
S
L
S
D
V
E
W
I
Site 177
S2523
Q
H
A
D
V
S
L
S
D
V
E
W
I
R
H
Site 178
S2542
M
E
A
G
E
Q
L
S
R
D
G
F
H
R
L
Site 179
S2558
Q
L
L
K
D
L
A
S
K
G
N
L
E
W
L
Site 180
Y2575
A
K
H
E
A
I
V
Y
R
H
R
Q
A
L
E
Site 181
S2583
R
H
R
Q
A
L
E
S
Q
D
T
R
I
S
S
Site 182
T2586
Q
A
L
E
S
Q
D
T
R
I
S
S
R
Q
S
Site 183
S2589
E
S
Q
D
T
R
I
S
S
R
Q
S
M
S
P
Site 184
S2590
S
Q
D
T
R
I
S
S
R
Q
S
M
S
P
K
Site 185
S2593
T
R
I
S
S
R
Q
S
M
S
P
K
Y
L
K
Site 186
S2595
I
S
S
R
Q
S
M
S
P
K
Y
L
K
V
I
Site 187
Y2598
R
Q
S
M
S
P
K
Y
L
K
V
I
P
P
I
Site 188
S2624
L
A
V
P
T
Q
K
S
P
L
A
T
K
R
I
Site 189
T2628
T
Q
K
S
P
L
A
T
K
R
I
P
D
P
R
Site 190
S2648
L
L
G
E
P
Y
R
S
E
R
A
Q
Q
I
S
Site 191
S2655
S
E
R
A
Q
Q
I
S
I
A
H
K
E
M
E
Site 192
Y2665
H
K
E
M
E
M
Q
Y
F
Y
P
A
T
R
D
Site 193
Y2667
E
M
E
M
Q
Y
F
Y
P
A
T
R
D
I
F
Site 194
S2676
A
T
R
D
I
F
P
S
A
H
A
S
V
E
K
Site 195
T2713
L
P
K
L
E
K
K
T
Q
P
I
S
K
K
K
Site 196
S2717
E
K
K
T
Q
P
I
S
K
K
K
E
E
L
P
Site 197
T2728
E
E
L
P
L
W
E
T
F
V
A
L
Y
H
V
Site 198
Y2733
W
E
T
F
V
A
L
Y
H
V
L
R
M
L
Q
Site 199
Y2743
L
R
M
L
Q
Q
R
Y
P
K
D
S
T
A
W
Site 200
Y2761
F
Y
Q
L
M
D
L
Y
Q
L
K
S
P
R
I
Site 201
S2765
M
D
L
Y
Q
L
K
S
P
R
I
Q
K
L
L
Site 202
Y2788
P
Q
P
Q
E
I
I
Y
E
E
A
L
K
A
T
Site 203
T2814
L
F
C
G
S
S
H
T
P
R
S
P
Q
E
F
Site 204
S2817
G
S
S
H
T
P
R
S
P
Q
E
F
Q
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation