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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC141
Full Name:
Coiled-coil domain-containing protein 141
Alias:
Type:
Mass (Da):
100581
Number AA:
875
UniProt ID:
Q6ZP82
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
S
L
K
E
F
Y
E
T
E
I
P
Q
K
E
Q
Site 2
S28
D
A
K
A
K
H
C
S
D
S
A
E
K
Q
W
Site 3
S30
K
A
K
H
C
S
D
S
A
E
K
Q
W
Q
L
Site 4
S42
W
Q
L
F
L
K
K
S
F
I
T
Q
D
L
G
Site 5
Y72
L
D
V
K
N
E
V
Y
L
M
K
N
T
M
E
Site 6
S89
K
A
E
R
E
E
L
S
L
L
R
L
A
W
Q
Site 7
S173
V
Q
Y
I
M
K
E
S
E
E
L
T
G
R
G
Site 8
T177
M
K
E
S
E
E
L
T
G
R
G
A
P
V
K
Site 9
S187
G
A
P
V
K
E
K
S
Q
Q
L
K
D
L
I
Site 10
Y207
Q
K
E
R
I
Q
D
Y
E
D
I
L
Y
K
V
Site 11
Y212
Q
D
Y
E
D
I
L
Y
K
V
V
Q
F
H
Q
Site 12
S230
E
L
G
R
L
I
K
S
R
E
L
E
F
V
E
Site 13
S255
V
Q
I
H
L
R
C
S
Q
E
K
Q
A
R
V
Site 14
S304
L
E
L
L
E
E
D
S
M
K
W
R
A
K
A
Site 15
Y314
W
R
A
K
A
E
E
Y
G
R
T
L
S
R
S
Site 16
T317
K
A
E
E
Y
G
R
T
L
S
R
S
V
E
Y
Site 17
S319
E
E
Y
G
R
T
L
S
R
S
V
E
Y
C
A
Site 18
S321
Y
G
R
T
L
S
R
S
V
E
Y
C
A
M
R
Site 19
S337
E
I
N
E
L
K
D
S
F
K
D
I
K
K
K
Site 20
S359
Y
T
K
K
N
E
K
S
R
N
L
K
A
L
K
Site 21
Y367
R
N
L
K
A
L
K
Y
Q
I
Q
Q
V
D
M
Site 22
Y375
Q
I
Q
Q
V
D
M
Y
A
E
K
M
Q
A
L
Site 23
S390
K
R
K
M
E
K
V
S
N
K
T
S
D
S
F
Site 24
S394
E
K
V
S
N
K
T
S
D
S
F
L
N
Y
P
Site 25
S396
V
S
N
K
T
S
D
S
F
L
N
Y
P
S
D
Site 26
Y400
T
S
D
S
F
L
N
Y
P
S
D
K
V
N
V
Site 27
Y429
F
D
K
V
V
T
D
Y
K
K
N
L
D
L
T
Site 28
T436
Y
K
K
N
L
D
L
T
E
H
F
Q
E
V
I
Site 29
Y450
I
E
E
C
H
F
W
Y
E
D
A
S
A
T
V
Site 30
T456
W
Y
E
D
A
S
A
T
V
V
R
V
G
K
Y
Site 31
S464
V
V
R
V
G
K
Y
S
T
E
C
K
T
K
E
Site 32
T499
E
E
R
I
Q
E
A
T
D
L
A
Q
H
L
Y
Site 33
Y506
T
D
L
A
Q
H
L
Y
G
L
E
E
G
Q
K
Site 34
Y514
G
L
E
E
G
Q
K
Y
I
E
K
I
V
T
K
Site 35
T520
K
Y
I
E
K
I
V
T
K
H
K
E
V
L
E
Site 36
S528
K
H
K
E
V
L
E
S
V
T
E
L
C
E
S
Site 37
S535
S
V
T
E
L
C
E
S
L
T
E
L
E
E
K
Site 38
Y560
P
N
L
E
D
F
H
Y
D
Y
I
D
L
L
K
Site 39
Y562
L
E
D
F
H
Y
D
Y
I
D
L
L
K
E
P
Site 40
S609
L
P
Q
D
L
K
V
S
T
D
K
E
G
G
V
Site 41
S627
L
L
P
E
D
M
L
S
G
E
E
Y
E
C
V
Site 42
Y631
D
M
L
S
G
E
E
Y
E
C
V
S
P
D
D
Site 43
S635
G
E
E
Y
E
C
V
S
P
D
D
I
S
L
P
Site 44
S640
C
V
S
P
D
D
I
S
L
P
P
L
P
G
S
Site 45
S647
S
L
P
P
L
P
G
S
P
E
S
P
L
A
P
Site 46
S650
P
L
P
G
S
P
E
S
P
L
A
P
S
D
M
Site 47
S665
E
V
E
E
P
V
S
S
S
L
S
L
H
I
S
Site 48
S666
V
E
E
P
V
S
S
S
L
S
L
H
I
S
S
Site 49
S668
E
P
V
S
S
S
L
S
L
H
I
S
S
Y
G
Site 50
T680
S
Y
G
V
Q
A
G
T
S
S
P
G
D
A
Q
Site 51
S682
G
V
Q
A
G
T
S
S
P
G
D
A
Q
E
S
Site 52
S689
S
P
G
D
A
Q
E
S
V
L
P
P
P
V
A
Site 53
T707
A
C
N
D
K
R
E
T
F
S
S
H
F
E
R
Site 54
S709
N
D
K
R
E
T
F
S
S
H
F
E
R
P
Y
Site 55
S710
D
K
R
E
T
F
S
S
H
F
E
R
P
Y
L
Site 56
Y716
S
S
H
F
E
R
P
Y
L
Q
F
K
A
E
P
Site 57
T726
F
K
A
E
P
P
L
T
S
R
G
F
V
E
K
Site 58
S734
S
R
G
F
V
E
K
S
T
A
L
H
R
I
S
Site 59
S741
S
T
A
L
H
R
I
S
A
E
H
P
E
S
M
Site 60
S747
I
S
A
E
H
P
E
S
M
M
S
E
V
H
E
Site 61
S750
E
H
P
E
S
M
M
S
E
V
H
E
R
A
L
Site 62
T783
A
D
N
N
F
T
K
T
Q
D
R
L
H
A
S
Site 63
S790
T
Q
D
R
L
H
A
S
S
D
A
F
S
G
L
Site 64
S791
Q
D
R
L
H
A
S
S
D
A
F
S
G
L
R
Site 65
S795
H
A
S
S
D
A
F
S
G
L
R
F
Q
S
G
Site 66
S801
F
S
G
L
R
F
Q
S
G
T
S
R
G
Y
Q
Site 67
T803
G
L
R
F
Q
S
G
T
S
R
G
Y
Q
R
Q
Site 68
Y807
Q
S
G
T
S
R
G
Y
Q
R
Q
M
V
P
R
Site 69
S819
V
P
R
E
E
I
K
S
T
S
A
K
S
S
V
Site 70
T820
P
R
E
E
I
K
S
T
S
A
K
S
S
V
V
Site 71
S821
R
E
E
I
K
S
T
S
A
K
S
S
V
V
S
Site 72
S824
I
K
S
T
S
A
K
S
S
V
V
S
L
A
D
Site 73
S825
K
S
T
S
A
K
S
S
V
V
S
L
A
D
Q
Site 74
S828
S
A
K
S
S
V
V
S
L
A
D
Q
A
P
N
Site 75
S841
P
N
F
S
R
L
L
S
N
V
T
V
M
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation