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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FRRS1
Full Name:
Ferric-chelate reductase 1
Alias:
Stromal cell-derived receptor 2
Type:
Mass (Da):
66114
Number AA:
592
UniProt ID:
Q6ZNA5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
H
I
S
Y
V
A
N
Y
P
N
G
K
V
T
Q
Site 2
S42
M
I
P
E
H
G
H
S
P
Q
S
V
P
V
H
Site 3
S45
E
H
G
H
S
P
Q
S
V
P
V
H
D
I
Y
Site 4
Y52
S
V
P
V
H
D
I
Y
V
S
Q
M
T
F
R
Site 5
T57
D
I
Y
V
S
Q
M
T
F
R
P
G
D
Q
I
Site 6
T67
P
G
D
Q
I
E
V
T
L
S
G
H
P
F
K
Site 7
S69
D
Q
I
E
V
T
L
S
G
H
P
F
K
G
F
Site 8
T106
S
E
V
S
Q
L
L
T
C
E
D
I
Q
G
S
Site 9
S113
T
C
E
D
I
Q
G
S
A
V
S
H
R
S
A
Site 10
S116
D
I
Q
G
S
A
V
S
H
R
S
A
S
K
K
Site 11
S119
G
S
A
V
S
H
R
S
A
S
K
K
T
E
I
Site 12
S121
A
V
S
H
R
S
A
S
K
K
T
E
I
K
V
Site 13
Y129
K
K
T
E
I
K
V
Y
W
N
A
P
S
S
A
Site 14
Y153
V
V
E
K
Y
K
I
Y
W
V
K
I
P
G
P
Site 15
S187
L
P
T
L
P
P
V
S
H
L
T
K
P
F
S
Site 16
T190
L
P
P
V
S
H
L
T
K
P
F
S
A
S
D
Site 17
S194
S
H
L
T
K
P
F
S
A
S
D
C
G
N
K
Site 18
S196
L
T
K
P
F
S
A
S
D
C
G
N
K
K
F
Site 19
S207
N
K
K
F
C
I
R
S
P
L
N
C
D
P
E
Site 20
S218
C
D
P
E
K
E
A
S
C
V
F
L
S
F
T
Site 21
S223
E
A
S
C
V
F
L
S
F
T
R
D
D
Q
S
Site 22
S230
S
F
T
R
D
D
Q
S
V
M
V
E
M
S
G
Site 23
S236
Q
S
V
M
V
E
M
S
G
P
S
K
G
Y
L
Site 24
Y242
M
S
G
P
S
K
G
Y
L
S
F
A
L
S
H
Site 25
S244
G
P
S
K
G
Y
L
S
F
A
L
S
H
D
Q
Site 26
Y259
W
M
G
D
D
D
A
Y
L
C
I
H
E
D
Q
Site 27
Y269
I
H
E
D
Q
T
V
Y
I
Q
P
S
H
L
T
Site 28
T276
Y
I
Q
P
S
H
L
T
G
R
S
H
P
V
M
Site 29
S279
P
S
H
L
T
G
R
S
H
P
V
M
D
S
R
Site 30
T288
P
V
M
D
S
R
D
T
L
E
D
M
A
W
R
Site 31
T310
C
S
F
R
R
N
I
T
L
P
G
V
K
N
R
Site 32
T322
K
N
R
F
D
L
N
T
S
Y
Y
I
F
L
A
Site 33
Y324
R
F
D
L
N
T
S
Y
Y
I
F
L
A
D
G
Site 34
Y339
A
A
N
D
G
R
I
Y
K
H
S
Q
Q
P
L
Site 35
S342
D
G
R
I
Y
K
H
S
Q
Q
P
L
I
T
Y
Site 36
Y352
P
L
I
T
Y
E
K
Y
D
V
T
D
S
P
K
Site 37
T355
T
Y
E
K
Y
D
V
T
D
S
P
K
N
I
G
Site 38
S357
E
K
Y
D
V
T
D
S
P
K
N
I
G
G
S
Site 39
S364
S
P
K
N
I
G
G
S
H
S
V
L
L
L
K
Site 40
S511
P
G
L
N
L
P
D
S
W
K
T
Y
A
M
T
Site 41
Y536
V
V
L
E
V
H
A
Y
R
L
S
R
K
V
E
Site 42
S539
E
V
H
A
Y
R
L
S
R
K
V
E
I
L
D
Site 43
S555
D
R
I
Q
I
L
Q
S
F
T
A
V
E
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation