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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF574
Full Name:
Zinc finger protein 574
Alias:
FLJ22059; Zinc finger 574; ZN574
Type:
Unknown function
Mass (Da):
98900
Number AA:
896
UniProt ID:
Q6ZN55
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
T
E
E
S
E
E
T
V
L
Y
I
E
H
R
Site 2
Y11
E
S
E
E
T
V
L
Y
I
E
H
R
Y
V
C
Site 3
Y16
V
L
Y
I
E
H
R
Y
V
C
S
E
C
N
Q
Site 4
Y25
C
S
E
C
N
Q
L
Y
G
S
L
E
E
V
L
Site 5
S27
E
C
N
Q
L
Y
G
S
L
E
E
V
L
M
H
Site 6
T58
D
P
G
V
T
V
A
T
D
T
A
S
G
T
G
Site 7
S62
T
V
A
T
D
T
A
S
G
T
G
L
Y
Q
T
Site 8
T69
S
G
T
G
L
Y
Q
T
L
V
Q
E
S
Q
Y
Site 9
Y76
T
L
V
Q
E
S
Q
Y
Q
C
L
E
C
G
Q
Site 10
S87
E
C
G
Q
L
L
M
S
P
S
Q
L
L
E
H
Site 11
S89
G
Q
L
L
M
S
P
S
Q
L
L
E
H
Q
E
Site 12
S113
E
A
V
P
A
E
P
S
P
K
A
P
P
L
S
Site 13
S120
S
P
K
A
P
P
L
S
S
S
T
I
H
Y
E
Site 14
S122
K
A
P
P
L
S
S
S
T
I
H
Y
E
C
V
Site 15
Y126
L
S
S
S
T
I
H
Y
E
C
V
D
C
K
A
Site 16
S137
D
C
K
A
L
F
A
S
Q
E
L
W
L
N
H
Site 17
T147
L
W
L
N
H
R
Q
T
H
L
R
A
T
P
T
Site 18
T152
R
Q
T
H
L
R
A
T
P
T
K
A
P
A
P
Site 19
T154
T
H
L
R
A
T
P
T
K
A
P
A
P
V
V
Site 20
S164
P
A
P
V
V
L
G
S
P
V
V
L
G
P
P
Site 21
S182
A
R
V
A
V
E
H
S
Y
R
K
A
E
E
G
Site 22
Y183
R
V
A
V
E
H
S
Y
R
K
A
E
E
G
G
Site 23
Y214
T
E
V
E
L
L
L
Y
K
C
S
E
C
S
Q
Site 24
S220
L
Y
K
C
S
E
C
S
Q
L
F
Q
L
P
A
Site 25
T235
D
F
L
E
H
Q
A
T
H
F
P
A
P
V
P
Site 26
S244
F
P
A
P
V
P
E
S
Q
E
P
A
L
Q
Q
Site 27
S257
Q
Q
E
V
Q
A
S
S
P
A
E
V
P
V
S
Site 28
S264
S
P
A
E
V
P
V
S
Q
P
D
P
L
P
A
Site 29
S272
Q
P
D
P
L
P
A
S
D
H
S
Y
E
L
R
Site 30
S275
P
L
P
A
S
D
H
S
Y
E
L
R
N
G
E
Site 31
Y276
L
P
A
S
D
H
S
Y
E
L
R
N
G
E
A
Site 32
S298
R
R
A
R
R
N
N
S
G
E
A
G
G
A
A
Site 33
S320
A
C
D
Q
L
F
L
S
P
H
Q
L
Q
Q
H
Site 34
S330
Q
L
Q
Q
H
L
R
S
H
R
E
G
V
F
K
Site 35
S347
L
C
S
R
V
F
P
S
P
S
S
L
D
Q
H
Site 36
S349
S
R
V
F
P
S
P
S
S
L
D
Q
H
L
G
Site 37
S350
R
V
F
P
S
P
S
S
L
D
Q
H
L
G
D
Site 38
S359
D
Q
H
L
G
D
H
S
S
E
S
H
F
L
C
Site 39
S360
Q
H
L
G
D
H
S
S
E
S
H
F
L
C
V
Site 40
T387
L
A
H
R
R
A
H
T
P
N
P
L
H
S
C
Site 41
Y408
V
N
L
T
K
F
L
Y
H
R
R
T
H
G
V
Site 42
T412
K
F
L
Y
H
R
R
T
H
G
V
G
G
V
P
Site 43
T422
V
G
G
V
P
L
P
T
T
P
V
P
P
E
E
Site 44
T423
G
G
V
P
L
P
T
T
P
V
P
P
E
E
P
Site 45
S453
E
A
P
E
P
P
V
S
E
E
T
S
A
G
P
Site 46
S457
P
P
V
S
E
E
T
S
A
G
P
A
A
P
G
Site 47
S508
G
K
M
F
K
K
K
S
H
V
R
N
H
L
R
Site 48
T516
H
V
R
N
H
L
R
T
H
T
G
E
R
P
F
Site 49
T518
R
N
H
L
R
T
H
T
G
E
R
P
F
P
C
Site 50
S529
P
F
P
C
P
D
C
S
K
P
F
N
S
P
A
Site 51
S534
D
C
S
K
P
F
N
S
P
A
N
L
A
R
H
Site 52
T544
N
L
A
R
H
R
L
T
H
T
G
E
R
P
Y
Site 53
Y551
T
H
T
G
E
R
P
Y
R
C
G
D
C
G
K
Site 54
T561
G
D
C
G
K
A
F
T
Q
S
S
T
L
R
Q
Site 55
S563
C
G
K
A
F
T
Q
S
S
T
L
R
Q
H
R
Site 56
S564
G
K
A
F
T
Q
S
S
T
L
R
Q
H
R
L
Site 57
T565
K
A
F
T
Q
S
S
T
L
R
Q
H
R
L
V
Site 58
Y592
G
V
R
F
H
R
P
Y
R
L
L
M
H
R
Y
Site 59
Y599
Y
R
L
L
M
H
R
Y
H
H
T
G
E
Y
P
Site 60
Y605
R
Y
H
H
T
G
E
Y
P
Y
K
C
R
E
C
Site 61
Y607
H
H
T
G
E
Y
P
Y
K
C
R
E
C
P
R
Site 62
S615
K
C
R
E
C
P
R
S
F
L
L
R
R
L
L
Site 63
S640
R
Q
P
H
R
C
P
S
C
G
A
A
F
P
S
Site 64
S647
S
C
G
A
A
F
P
S
S
L
R
L
R
E
H
Site 65
S648
C
G
A
A
F
P
S
S
L
R
L
R
E
H
R
Site 66
T671
P
R
R
F
E
C
G
T
C
G
K
K
V
G
S
Site 67
S678
T
C
G
K
K
V
G
S
A
A
R
L
Q
A
H
Site 68
T711
A
P
R
A
P
R
A
T
R
A
P
V
A
S
P
Site 69
S717
A
T
R
A
P
V
A
S
P
A
A
L
G
S
T
Site 70
T724
S
P
A
A
L
G
S
T
A
T
A
S
P
A
A
Site 71
S728
L
G
S
T
A
T
A
S
P
A
A
P
A
R
R
Site 72
S741
R
R
R
G
L
E
C
S
E
C
K
K
L
F
S
Site 73
S748
S
E
C
K
K
L
F
S
T
E
T
S
L
Q
V
Site 74
S752
K
L
F
S
T
E
T
S
L
Q
V
H
R
R
I
Site 75
T761
Q
V
H
R
R
I
H
T
G
E
R
P
Y
P
C
Site 76
Y766
I
H
T
G
E
R
P
Y
P
C
P
D
C
G
K
Site 77
S778
C
G
K
A
F
R
Q
S
T
H
L
K
D
H
R
Site 78
T779
G
K
A
F
R
Q
S
T
H
L
K
D
H
R
R
Site 79
T789
K
D
H
R
R
L
H
T
G
E
R
P
F
A
C
Site 80
S806
C
G
K
A
F
A
I
S
M
R
L
A
E
H
R
Site 81
T817
A
E
H
R
R
I
H
T
G
E
R
P
Y
S
C
Site 82
Y822
I
H
T
G
E
R
P
Y
S
C
P
D
C
G
K
Site 83
S823
H
T
G
E
R
P
Y
S
C
P
D
C
G
K
S
Site 84
S830
S
C
P
D
C
G
K
S
Y
R
S
F
S
N
L
Site 85
Y831
C
P
D
C
G
K
S
Y
R
S
F
S
N
L
W
Site 86
S835
G
K
S
Y
R
S
F
S
N
L
W
K
H
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation